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Linearity in Medical News

GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.

...active and total inhibitors were attained within 2 to 4 hours of dose administration. While the recommended therapeutic dose range is 10 to 80 mg/day, linearity of inhibitory activity in the general circulation was established by a single dose study employing lovastatin tablet dosages from 60 to as high as 120...
Linearity in Medical Technology

Genaera Releases Phase 1 Data and New Preclinical Data on the CNS Function of Trodusquemine (MSI-1436) at CBI Obesity Summit

...arameters. Moreover, PK profiles of MSI-1436 in the four cohorts of the study showed a consistent pattern with minimal subject-to-subject variability. linearity of peak trodusquemine concentration (Cmax) was observed across the range of doses studied. Values for a wide range of endocrine and metabolic biomarke...

Ekkyo Describes the First Benefits of Controlled Hyperthermia in Humans in "Lasers in Surgery and Medicine"

... Patients were treated with doses ranging between 80 and 120 J/cm2. Scar appearance was evaluated for inflammation, thickness, width, discretion and linearity by surgeon and patient at 10 days, 3 months, and 12 months. The final scar analysis at 12 months after laser treatment showed that the treated porti...

Genaera Corporation Provides Highlights of Positive Phase 1 Trodusquemine (MSI-1436) Data from the North American Association for the Study of Obesity Annual Meeting

... profiles of trodusquemine in the first five cohorts of the study showed a consistent pattern with minimal subject-to-subject variability and linearity was observed across the range of doses studied. Values for a wide range of endocrine and metabolic biomarkers as well as evaluations of mood a...

Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference

...dose groups. According to Dr. DelConte, PK profiles from the study thus far show a predictable pattern with minimal subject-to-subject variability and linearity across the range of doses studied. To date, no serious adverse events have been reported. It was emphasized that further study is needed to establish ...

BDSI Announces Positive Phase III Clinical Trial Results for BEMA Fentanyl

...red in these patients. The results also demonstrated that the dosage form was convenient and comfortable to use. Importantly, we believe that the dose linearity (i.e. double the dose and double the plasma concentration of the drug) demonstrated in our previously announced pharmacokinetic studies up to the 1200...

Tight Glycemic Control in the ICU

...esults appear in 26 seconds. Studies have shown that the Accu-Chek meter is accurate over a wide range of glucose concentrations. QC tests include a linearity kit, and glucose control solutions that come with the test strips. The meter has a rechargeable battery, barcode scanner, and memory of 4000 measurem...
Linearity in Medical Products

Sugar-Chex Linearity Glucose Control

Description: Sugar-Chex Linearity is a whole blood formulation designed to cover the linear reportable range of the most popular glucose meters. The product meets CAP recommendations of using a control matrix that closely resembles patient samples. Sugar-Chex Linearity is packaged in ready-to-use dropper vials ...
Company:Streck

Retic-Chex Linearity Control

Description: Retic-Chex Linearity is designed to establish the patient reportable range and establish the analytic linearity of the system. Retic-Chex Linearity is available in five-vial sets with values assigned for Abbott CELL-DYN 3200, 3500, 3700 and 4000; Bayer ADVIA 120; Coulter STKS, MAXM, HmX, GENS and L...
Company:Streck

CVA and CVA for CELL-DYN Linearity Control Kits

Description: CVA and CVA for CELL-DYN are assayed linearity control kits that are used to assess calibration and to verify patient reportable range of three- and five-part hematology instruments. The kits also measure the linear performance of the analyzer. CVA and CVA for CELL-DYN kits have customized ranges a...
Company:Streck

Microalbumin Linearity Control

Description: Microalbumin Linearity Control...
Company:Kamiya Biomedical Company

Lyphochek Hemoglobin A1C Linearity Set

Description: Lyphochek® Hemoglobin A1C Linearity Set is a human whole blood based product designed to verify linearity throughout the patient reportable range of hemoglobin A1C assays....
Company:Bio-Rad Laboratories

CVC 9005 Hematocrit Calibration Verification Control (for use with the IRMA TRUpoint Blood Analysis System)

Description:... CVC 9005 Hematocrit Calibration Verification Controls are materials used for verifying the calibration and linearity of hematocrit sensors in IRMA TRUpoint cartridges for systems using software version 7.0 or higher....
Company:RNA Medical

CVC 123 Calibration Verification Controls

Description:... CVC 123 is an assayed quality control material used for confirming the calibration and linearity of blood gas, electrolyte, and metabolite instrumentation....
Company:RNA Medical

CVC 223 CO-Oximeter Calibration Verification Controls

Description:... CVC 223 is an assayed quality control material used for confirming the calibration and linearity of CO-Oximeter instrumentation....
Company:RNA Medical

5mm ENDOlap™ Laparoscopes

Description:... ENDOlap™ laparoscopes provide excellent image linearity and flatness of field....
Company:Cardinal Health, Inc.

10mm ENDOlap™ Millennium Laparoscopes

Description:... ENDOlap™ laparoscopes provide excellent image linearity and flatness of field....
Company:Cardinal Health, Inc.
Linearity in Biological Technology

One of Nation's Oldest Blood Services Providers Turns to Sysmex America

...t (direct) and platelet count. It has the extended linearity capabilities required for the concentrated cell pr...y-to-use operating system and an extended platelet linearity of up to 5,000 x 10/ul and HCT linearity up to 75%. Sysmex's state-of-the-art Interlaborato...

Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column

...ng for a substantial decrease in column "break-in" time from two weeks to 4 days as well as better peak area reproducibility and linearity of both monomer and aggregate species. As a precaution, a more rigorous cleaning protocol consisting of flushing ...

The New Affymetrix GeneChip Scanner 3000

...ed design improvements resulting in: Space savings Increased speed Integrated sample tracking Automation Robust linearity Higher resolution Greater data integrity Improved assay performance Many of the technical features and specifications o...

The Affymetrix GeneChip Scanner 3000 New Advances in Scanner Design for Superior Performance, Reliability, and Dynamic Range

...ly locate each fluorescent pixel. Optic aberrations and galvanometer imperfections no longer dominate scan linearity; thus, consistently accurate scan linearity and excellent gridding performance are ensured. The scan arm is physically small, enabling the objective, a low-mass, high-Numerical Aperture (...

New statistical algorithms for Monitoring Gene Expression on GeneChip® Probe Arrays

...nsitivity and specificity may be varied in a predictable fashion by varying the default setting for p-value cutoff. Figure 4 illustrates the linearity of dose response from the 14 spiked transcripts and the upper and lower confidence limits. It also demonstrates that signal calculation in the statist...

Determination of Acepromazine and its Major Metabolite in Equine Serum by LC-MS/MS using the Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

.... Quantitation and Linear Dynamic Range Figures 2 and 3 show calibration curves for ACE and HEPS in horse serum with linearity over four orders of magnitude, i.e., 0.2 200 ng/mL. The R2 value is 0.9952 for ACE and 0.9922 for HEPS. These calibration curves were generated with ...

Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS

...ting yielded the following equation: y = 5.5997 10 4 + 0.0206125x. The correlation coefficient for this curve was r 2 =0.9999, indicating excellent linearity across the four order-of-magnitude dynamic range. Table 1 lists the statistical results for the acrylamide calibration curve. At the LOQ, the accuracy...

Sensitivity and Quantitation using a Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

...lprazolam over the entire range of the assay is shown in Figure 5, with the linearity over the dynamic range from 500 fg to 5 ng on-column. The correlation coeff...s in biological matrices. Benzodiazapines were successfully quantified with linearity over four orders of magnitude for alprazolam. The CV was around 5-7% except...

Microdetermination of Phosphorus Using the SpectraMax Plus Microplate Spectrophotometer: Choice of Microplate, Cuvette, or Test Tube Assay Formats (MaxLine Application Note #24)

...read in 12 x 75 glass tubes and in a microplate. Both curves have excellent linearity from 1 mg/dL to 25 mg/dL based on the concentration of the original samples... tubes or transferred to a standard 1 cm cuvette. All curves have excellent linearity from 0.078 g/mL to 5 g/mL. The standards have slightly higher absorbance wh...

LIVE/DEAD Viability/Cytotoxicity Assay for Animal Cells Using the SpectraMax Gemini XS Fluorescence Microplate Reader (MaxLine Application Note #43)

...spectively. All of the wells containing live cells, dead cells and PBS only were scanned under optimal Ex/Em conditions for each dye to determine the linearity (Tables 1A, B). The CV% for all cell dilutions was well below 10%. The linear curve for live cells was compared to that obtained with the same number ...
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(Date:10/1/2014)... protein beta-amyloid is strongly associated with Alzheimer,s disease; however, ... peptide is the causal agent of the onset and ... confirmation is that beta-amyloid is not harmful when found ... when it self-assembles to form the so-called amyloid fibrils ... beta-amyloid alone, but with multiple ones because each aggregate ...
(Date:10/1/2014)... Philadelphia, PA, October 1, 2014 Patients with ... treatment, have a greatly increased risk of depression. ... therapy for chronic hepatitis C virus infection causes ... Omega-3 fatty acids, more commonly known as fish ... including lowering the risk of heart disease and ...
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(Date:9/30/2014)... it comes to using marijuana, new research, involving mice ... Journal of Leukocyte Biology , suggests ... that you should. That,s because a team of Italian ... do serious long-term damage to the immune system. This ... diseases, such as multiple sclerosis, inflammatory bowel disease and ...
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Breaking Biology News(10 mins):Adolescent exposure to thc may cause immune systems to go up in smoke 2Spectra Automation Introduces RECONN Bioprocess Manager 2Slim cigarette smokers not exposed to more harmful chemicals 2
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