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Leiden in Medical News

No Benefit in Testing for Genes Linked to Leg Clots

...tentially dangerous blood clots called deep vein thrombosis, a new U.S. government report shows. The presence of two gene mutations called Factor V leiden and prothrombin G20210A can signal continued risk of blood clots, according to background information in the study. But Agency for Healthcare Resea...

People With Huntington's Report Discrimination

...discrimination Act to prevent the use of genetic information by health insurance companies or employers. An accompanying editorial by Aad Tibben of leiden University in the Netherlands discusses the benefits of genetic testing, saying it "gives a person at risk the opportunity to take more responsibility...

Cepheid Receives Health Canada License for Xpert(R) HemosIL(R) FII & FV Test

... that Health Canada has issued Cepheid a medical device license for its Xpert HemosIL FII & FV test. The test detects Factor II (FII) and Factor V leiden (FV) genetic variations associated with thrombophilia, an increased risk of blood clots (thrombosis). Xpert HemosIL FII & FV delivers results in j...

Researchers call for new space headache category following astronauts' survey

...rwise super healthy subjects" says lead researcher Dr Alla Vein from Professor Michel Ferrari's Headache Research team at the Department of Neurology, leiden University Medical Center, The Netherlands. "We propose to classify space headache as a separate entity among the secondary headaches attributed to...

Some Antidepressants May Thwart Tamoxifen's Effect on Breast Cancer

...percent of those receiving tamoxifen alone; that translates into an almost twofold increase in risk. The second study, conducted by researchers at leiden University Medical Center in the Netherlands, collected information on almost 2,000 breast cancer patients using tamoxifen, 215 of whom had used an SS...

Stem Cells May Offer New Way to Treat Blocked Arteries

...o options left," said Dr. Douwe E. Atsma, an interventional cardiologist at leiden University Medical Center and an author of the study, which appears in the ... SOURCES: Douwe E. Atsma, M.D., Ph.D., interventional cardiologist, leiden University Medical Center, The Netherlands; Amit Patel, M.D., director, car...

Boston Scientific Announces European Approval and First Implants of New Defibrillation Lead System Designed to Simplify the Surgical Process

... Johannes Heintze, M.D., Herz und Diabeteszentrum Nordrhein-Westfalen Bad Oeynhausen, Bad Oeynhausen, Germany Lieselot van Erven, M.D., leiden University Medical Center, Leiden, The Netherlands Boston Scientific is a worldwide developer, manufacturer and marketer of medica...

Instrumentation Laboratory Wins Patent Infringement and Unfair Competition Trial Against Diagnostica Stago Relating to Reagents for Hemostasis Diagnostics

...IL and Chromogenix reagent product line offers a broad spectrum of diagnostic tests, including assays for the detection of APC resistance and factor V leiden mutations. We are committed to providing current and future customers around the world with these tests, to ensure that all hemostasis labs have acce...

Genetic risk factors play role in autoantibody-negative rheumatoid arthritis

...s variant from autoantibody-negative RA, which is less destructive, is considered increasingly important. A new study led by Diane van der Woude of leiden University Medical Center in The Netherlands examined 148 twin pairs in which one twin had RA. Participants were tested for antibodies known as anti-c...

Grapefruit-Heavy Diet Helped Spur Dangerous Clot

... Dr. Raul Mendez, another physician involved in the case, recommended a series of follow-up tests. One of them showed that the woman had the factor V leiden mutation, which also increases the risk of blood clots. So it was the combination of grapefruit juice, the estrogen in the birth control pill, the ...
Leiden in Medical Technology

Value of Genetic Testing for Preventing Blood Clots Unproven, According to New AHRQ Study

..., also failed to find any benefit from genetic testing of family members of patients who have at least one of the two mutations -- known as Factor V leiden (FVL) and prothrombin G20210A -- as well as a history of deep-vein thrombosis. As many as 600,000 Americans each year may have deep-vein throm...

TriLink BioTechnologies, Inc. Announces Supply Agreement With Osmetech Molecular Diagnostics

...lable while planned menu expansion includes an extended warfarin panel with the proprietary 4F2 marker, a venous thrombosis panel (Factor II, Factor V leiden and MTHFR) and a RESPLEX(R) respiratory pathogen assay marketed in collaboration with Qiagen that is capable of detecting Swine Flu. For more informa...

Athera Biotechnologies and Dyax Announce a Collaboration to Discover and Develop Antibodies for Cardiovascular Inflammation

...ead by Karolinska Institutet. The project involves 10 academic and industrial partners, including Phadia GmbH, Johannes Gutenberg-University Mainz and leiden University Medical Center. For further information see http://www.athera.se . Contact: Carina Schmidt, CEO, Phone: +46705525115, Mail: c.schmidt@at...

Cell Therapeutics Announces that the European Organization for Research and Treatment of Cancer Completes Enrollment in Phase II Clinical Trial of Brostallicin as First Line Therapy for Advanced or Metastatic Soft Tissue Sarcoma

...vanced or metastatic soft tissue sarcoma." Hans Gelderblom, M.D., Ph.D., of leiden University Medical Center in the Netherlands, is the Principal Investigator... E: sandrine.marreaud@eortc.be Study Coordinator Jans Gelderblom leiden University Medical Centre T: +31 71 526 34 86 F: +31 71 526 67 60 E: ...

Aeras, Crucell and South African Tuberculosis Vaccine Initiative Announce Encouraging Preliminary Results of Tuberculosis Vaccine Clinical Trial in South Africa

...he biopharmaceutical industry. Important partners and licensees include DSM Biologics, sanofi aventis, GSK and Merck & Co. Crucell is headquartered in leiden (the Netherlands), with subsidiaries in Switzerland, Spain, Italy, Sweden, Korea and the US. The Company employs over a 1000 people. For more informat...

Sanofi Pasteur Initiates Phase II Trial of Cell Culture-Based Seasonal Influenza Vaccine

...ldwide. The company licenses its PER.C6(R) production technology and other technologies to the biopharmaceutical industry. Crucell is headquartered in leiden (The Netherlands) and employs over a 1000 people. For more information, please visit http://www.crucell.com . About sanofi-aventis Sanofi-aventis, ...

Intercell AG: Novel tuberculosis Vaccine Shows Promising Immunogenicity and Safety Profile

... the 3rd Vienna Vaccines Conference by co-investigator Prof. Tom Ottenhoff, leiden University Medical Center, Netherlands. Based on these results the partners... the Department of Infectious Diseases (headed by Prof. Jaap van Dissel) at leiden University Medical Center in the Netherlands and was supported by the Europ...
Leiden in Medical Products

Pefakit APC-R Factor V Leiden Control

Description: Controls for APC Resistance / Factor V Leiden Functional Assay...
Company:Centerchem, Inc.

Factor V Leiden Functional Assay with Reflex to PCR

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Factor V Leiden by PCR & Fluorescence Monitoring

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Factor V Leiden Functional Assay

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

APC Resistance Profile with Reflex to Factor V Leiden

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Pefakit APC-R Factor V Leiden

Description: Pefakit APC-R FVL is a new functional test which exhibits 100% sensitivity and 100% specificity for Activated Protein C Resistance caused by the Factor V Leiden mutation (FV:Q506). In contrast to other commercially available methods, Pefakit APC-R FVL shows no interference from protein C or S, Lupu...
Company:Centerchem, Inc.

Coatest APC Resistance V Kit

Features:...ation analyzers. Validated, FDA cleared test kit removes the uncertainty of in-house research methods. Normal plasma control and heterozygous FV leiden control provided for verifying results. aPTT based assay is faster, more convenient and cost effective than PCR. Strongly reduces the influence ...
Company:DiaPharma Group, Inc.

ACL Advance Coagulation Analyzer

Features:...proved operator safety with the protective transparent cover Superior test menu including special assays, such as D-Dimer, new free Protein S, APCR-V leiden and von Willebrand. ...
Company:Beckman Coulter, Inc.

ACL 100 Coagulation Analyzer

Features:... Fully automated to increase efficiency Clotting assays include Lupus and APCR-V leiden Proven technology provides accurate results 110 throughput per hour for PT and Fibrinogen Minimum maintenance required ...
Company:Beckman Coulter, Inc.

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Leiden in Medical Dictionary

Hypercoagulable states

...ndary hypercoagulable states consist of a heterogeneous ... Inherited Hypercoagulable States . Resistance to activated protein C/factor V leiden ... Hypercoagulable state associated with other clinical conditions ... Topics: Introduction | Hypercoagulable States | Prophylaxis of Ven...
Leiden in Biological News

Leicester research paves way for first use in Europe of an insect to fight invasive plant

... at Leicester had shown that the European Japanese Knotweed was probably introduced from Japan as a garden plant by PF von Siebold from his nursery in leiden in the 1850s. The molecular tools to discover the origin of Japanese Knotweed were in place and the trip to Japan already arranged. That Japanese ...

Discovery to aid in future treatments of third-world parasites

...h2 responses but is unable to initiate them. However, new findings from an international study between Mohrs, Schramm, and Maria Yazdanbaksh of the leiden University Medical Center in the Netherlands have now shown that omega-1, a single protein secreted from schistosome eggs, recapitulates the activitie...

New drug agent knocks out multiple enzymes in cancer pathway

...owth and invasiveness. Tadahiko Kubo, of Hiroshima University, then found that BPH-715 also killed tumor cells in mice. And Socrates Papapoulos, of leiden University, the Netherlands, showed that the compound had a very low chemical affinity for bone. In humans, compounds like BPH-715 and zoledronate...

Synthesizing the most natural of all skin creams

... Prof. Joke Bouwstra, a specialist in the skin barrier and its synthesis at leiden University, and her colleague Robert Rimann set out to study VC in detail a... beamline at the ESRF (European Synchrotron Radiation Facility) allowed the leiden researchers to find the proportions of the various forms in the cream, even...

Climate change opens new avenue for spread of invasive plants

...ly Morrin and Wim van der Putten of The Netherlands Institute of Ecology, with collaborators from the University of Florida, Wageningen University and leiden University, the researchers compared exotic plant species that had recently established in Millingerwaard, a nature preserve in The Netherlands, with ...

Study looks at psychological impact of gene test for breast cancer

...testing for hereditary breast canceran increasingly used genetic test in which an "inconclusive" result is common. Sandra van Dijk, M.A., Ph.D., of leiden University Medical Center, The Netherlands, assessed psychological adjustment in 215 women who underwent DNA testing for BRCA gene mutations associate...

Killer whales, blind bats, discriminating dolphins, mating birds

... common in urban environments in the future, and which will retreat to quieter habitats. Hans Slabbekoorn ( H.W.Slabbekoorn@Biology.LeidenUniv.NL ) of leiden University in The Netherlands studies variations in birdsong; birds rely on these vocalizations to defend their territory and attract a mate, but more...

EuroDYNA takes lid off the genome

...nucleus is only now becoming clear, as is its relevance both for cell replication and gene expression. At the EuroDYNA conference, John van Noort from leiden University in the Netherlands reported that the DNA molecule, which in humans and most mammals is about two metres in length but only 2 nanometres in ...

Leiden scientists sequence first female DNA

... Geneticists of leiden University Medical Centre (LUMC) are the first to ...nt. This has been installed in January 2007 in the leiden Genome Technology Center, the genomics facility of.... Dr. Johan den Dunnen, project leader at the leiden Genome Technology Center: 'This high coverage is n...

Living with lions

...close to 1000 US$ per family each year. Scientists from the Resource Ecology Group, Wageningen University and the Institute of Environmental Sciences, leiden University, investigated the factors that contributed to these losses and why pastoralists continued to graze their herds close to the lions hunting g...
Leiden in Biological Technology

First step to converting solar energy using 'artificial leaf'

...he online Early Edition of the PNAS journal in the week starting 29 June. leiden researcher Swapna Ganapathy has obtained her PhD based on this subject, und...a Spirulina, such that they resembled the pigments of bacteria. De Groot's leiden group then studied the structure of these semi-synthetic light antennae. ...

Lycera Closes $36 Million Series A Financing

... this program into Lycera generates an unparalleled opportunity for finding small molecules that selectively target this pathway." Clarus's Dr. leiden added, "Lycera combines two of the most exciting, new small-molecule approaches for treating autoimmune diseases. The company will leverage the compl...

Results of the Annual General Meeting Held on September 24, 2008

... 156,784 Kappler as a Director of the Company 6. To elect Dr Jeffrey 331,221,109 138,828 154,951 leiden as a Director of the Company 7. To elect Mr Patrick 330,949,493 412,089 153,306 Langlois as a Director of t...

Athera Biotechnology Founder Johan Frostegard and His Colleagues Win NACB Distinguished Abstract Award at AACC 2008

...ead by Karolinska Institutet. The project involves 10 academic and industrial partners, including Phadia GmbH, Johannes Gutenberg-University Mainz and leiden University Medical Center. ...

AMT Appoints Director Global Marketing and Sales

...h and marketing of a product for Crohn's disease. She started her career at Gist-Brocades in the Netherlands. She is a graduate of the University of leiden (the Netherlands), where she studied physics and obtained her medical degree from the University's Medical School with honors in 1986. About Amsterd...

Large-scale community protein annotation -- WikiProteins

...vides a method for community annotation on a huge scale. The article is written by Barend Mons of the Erasmus Medical Center in Rotterdam, and the leiden University Medical Center, The Netherlands, and his co-authors from Brazil, The Netherlands, Switzerland, the UK and the USA. They include Amos Bairoc...

Boost for Malaria Vaccine Development by Combining Strengths of Dutch and American Researchers

...nd, Radboud University Nijmegen Medical Centre and leiden University Medical Center. Sanaria Inc. is exclusi... at Radboud University Nijmegen Medical Centre and leiden University Medical Center (research led by Dr. Chr... Driven by knowledge, empowered by people. About leiden University Medical Center ...

Professor Strauf's research is Nature Photonics’ cover article

...rtment of Physics & Engineering Physics at Stevens Institute of Technology, along with colleagues from the University of California, Santa Barbara and leiden University (Netherlands), has authored the article, High-frequency single-photon source with polarization control, the cover article of the December 2...

Life Sciences Leader Joins Millennium Board of Directors

...9991220/MLNMLOGO ) "It is a pleasure to have Dr. leiden join the Millennium Board of Directors," said Debo... Prior to joining Abbott Laboratories in 2000, Dr. leiden was the Elkan R. Blout Professor of Biological Sci...deliver important drugs to patients in need." Dr. leiden earned both his medical degree and Ph.D. from the ...

A Large-Scale Research Project by a Dutch Consortium Addressing a Global Problem

...uticals B.V., Nobilon International B.V., OctoPlus N.V., ViroClinics B.V., Virosome Biologicals B.V., the Erasmus University Medical Center Rotterdam, leiden University, the University Medical Center Groningen, Utrecht University and the Netherlands Vaccine Institute. The project is an initiative of Top In...
Leiden in Biological Definition

Physiology

...ding the beginning of experimental physiology. Herman Boerhaave is sometimes referred to as the father of physiology due to his exemplary teaching in leiden and textbook 'Institutiones medicae'(1708). Areas of physiology Physiology has several independent subdivisions. Electrophysiology deals with...
Leiden in Biological Dictionary

Heterozygote

...y dictionary has ecology, physiology, ... Combined heterozygote factor V leiden mutation and anticardiolipin antibody ... Definition of heterozygot... Advantage at Major Histocompatibility ... Combined heterozygote factor V leiden ... The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2007, Colu...

Heterozygosity

...ociated. with high mean growth rate, but in ... Heterozygosity for the leiden mutation in the factor V gene (FVL) is common and ... Heterozygosity refers to the situation when an individual has a single leiden ... ... 3, which is affected by loss of heterozygosity (LOH) in variou...
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