What are protective effects of anti-ricin A-chain aptamer?

... Ricin, a lectin from the castor bean plant Ricinus communis is considered one of the most potent plant toxins. Ricin poisoning can cause severe tissue damage and infl...

New molecular insight into amboebic dysentery

...an's team discovered that EhROM1 processes surface lectin proteins, and collaborators at Stanford University found that it re-localizes posteriorly during lectin shedding. These findings suggest that EhROM1 facilitates lectin shedding and host immune system evasion by this pa...

How Montezuma gets his revenge

...M1 does cut one particular lectin, and the more EhROM1 they added, the more lectin pieces resulted. Every cell has on its surface proteins recognizable by...ing researchers at Stanford University then looked to see if EhROM1 follows lectin and sure enough found that EhROM1 clusters at the capthe cluster of surface...

JCI table of contents: May 22, 2008

...onal studies indicated that the molecule, which was named dendritic cell NK lectin group receptor-1 (DNGR-1), was an endocytic receptor and that if an antibod...umor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin AUTHOR CONTACT: Caetano Reis e Sousa Cancer Research UK, London, Unite...

Protein Helps ID Thyroid Cancer Nodules

...tin-3 finds them sooner, could cut unnecessary surgeries MONDAY, May 19 (HealthDay News) -- Testing thyroid nodules for the presence of a lectin molecule called galectin-3 could help improve identification of nodules with cancer and reduce the number of unnecessary surgeries, according to an It...

Mushroom Extract Protects Poultry From Parasite Diseases

... recent issue of the journal Poultry Science. The scientists injected lectin extracted from Fomitella fraxinea (a wood-rotting mushroom seen mostly on b...t loss and reduced fecal shedding of live parasites. This particular lectin is usually prepared under less-stringent conditions than are other mushroom...

Chronic Sinusitis Resulting From Weakene Immune System

...ts who benefited from surgery with nine who did not, the Hopkins team discovered suppressed levels of human beta defensin 2 (HBD2) and mannose binding lectin (MBL) in those whose symptoms returned. The proteins are naturally produced in the nose whenever the immune system detects foreign bacteria or fungi, ...

Breast feeding can prevent HIV infection transmission

...will be published in Journal of Clinical Investigation. The authors show that human milk can block the binding of HIV to the DC-SIGN (DC-SIGN, a DC lectin receptor, interacts with HIV and is found at high expression levels in tonsillar tissue), molecule expressed on dendritic cells and potently inhibit t...

Lectin in Biological News

Wheat can fatally starve insect predators

...arbohydrate complex in the Hessian fly larvae. The lectin acts as a key to the carbohydrate structure, known...n the larvae attack a resistant plant, the plant's lectin production quickly increases by as much as 3,000 t...d virulent, are capable of ridding their bodies of lectin and surviving. Avirulent larvae are unable to deac...

A healthier start to a pig's life

...a. A radical solution has been found by using a lectin obtained from the red kidney bean plant. Lectins a...ult diet." The EUREKA study showed that giving the lectin to piglets at 11-12 days old enhanced successful w...ied pig behaviour and the practical application of lectin in Swedish pig production. Professor Pierzynowski ...

Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria

...ng. They analyzed each strain of bacteria using lectin microarrays--small glass plates covered with dots of sugar-binding proteins called lectins. The lectin dots act like microbe Velcro. Bacteria with a surface sugar that matches a specific lectin stick to that...

The brain is broadly wired for reproduction

... a genetic tracing method that they previously developed for charting neural pathways. They first engineered mice in which GnRH neurons produce barley lectin (BL), a tracer molecule that travels upstream and downstream to connected neurons, and green fluorescent protein (GFP), to mark the producing cells. B...

Lectin in Biological Technology

Affitech and Omeros Enter Into Antibody Discovery and Development Agreement

...ted serine protease-2, mediates activation of the complement system via the lectin pathway and is linked to multiple potential indications across a wide range...or the function of, a principal complement activation pathway, known as the lectin pathway. Importantly, inhibition of MASP-2 does not appear to interfere wit...

The iCycler iQ and Amplifluor Detection Systems for Analysis of Genetically Modified Organisms in Foodstuffs, Rev A

... Primers were chosen to amplify part of the soy lectin gene. The master mix contained: ...es) 90 l dNTPs (2.5 mM) 90 l lectin gene forward primer (2.5 M) 90 l lectin gene reverse primer (including recognition sequenc...

Detection of Genetically Modified Soybean in Processed Foods Using Real-Time Quantitative PCR with SYBR Green I Dye on the DNA Engine Opticon 2 System

...ers that amplified a portion of the soy lectin gene were used to normalize the amount ... level. Comparing the relative C(t)s of lectin and EPSPS reactions from the GMO concentration ... when measured at 495nm. Primers for soy lectin and EPSPS were ordered from Sigma Genosys (The ...

Lectin in Biological Definition

Immune system

...group of serum proteins which is activated in a cascade fashion. Three different pathways, the classical , alternative , and mannose-binding lectin pathways, are involved in complement activation. The first recognizes antigen-antibody complexes, the second spontaneously activates on contact with...

Lectin in Biological Dictionary

Vitelline membrane

...ine membrane was found in Taber's Medical Dictionary Online, along with 60,000 other medical and nursing definitions and dictionary terms. ... A lectin with an affinity for certain sulphated polysaccharides, such as fucoidin and dextran sulphate, has been isolated from the vitelline membrane of he...

Avidin

... NeutrAvidin protein is a deglycosylated version of avidin , with a mass of approximately 60,000 daltons. As a result of carbohydrate removal, lectin binding is reduced to undetectable levels, yet biotin binding affinity is retained because the carbohydrate is not necessary for this activity. Ne...

Acrosome reaction

... the ... capacitation is not necessary for an agonist-induced acrosome reaction . ... Spontaneous acrosome reaction was assessed by FITC-PNA lectin before and after ... ...