Enzyme allows B cells to resist death, leading to leukemia
B cell chronic lymphocytic leukemia (B-CLL)is the most common leukemia in adults and is characterized by theprogressive accumulation of mature B lymphocytes in the blood, bonemarrow, and lymphatic tissues. It is believed that in the early stagesof disease, B-CLL is the result of an undefined defect in theprogrammed signals that trigger normal B cell death (apoptosis). LivioTrentin and colle...Scientists document complex genomic events leading to the birth of new genes
A team of scientists led by Peer Bork, Ph.D., Senior Bioinformatics Scientist at the European Molecular Biology Laboratory, report today in the journal Genome Research that they have identified a new primate-specific gene family that spans about 10% of human chromosome 2. Comprised of eight family members, the RGP gene cluster may help to explain what sets apart humans and other primates from the...Genetic links could unlock clues to leading cause of blindness
Age-related macular degeneration is the leading cause of blindness in older adults, yet researchers are still in the dark about many of the factors that cause this incurable disease. But new insight from University of Florida and German researchers bout a genetic link between rhesus monkeys with macular degeneration and humans could unlock secrets about the earliest stages of the disease,...Leading scientists rank endangered dolphins, porpoises most in need of immediate action
Leading marine scientists for the first time have assessed dolphin and porpoise populations around the world which are severely threatened by entanglement in fishing gear and recommended nine urgent priorities for action in a report commissioned by the World Wildlife Fund. These nine projects highlight species threatened by bycatch that will most likely benefit from immediate action and will cont...Why do aneurysms form? New studies suggest leading role for white blood cells
Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out. But despite the deadly toll of this condition, called abdominal aortic aneurysm or AAA ("triple A"), experts know very...Visions, Part II: Preizler sees IT leading incremental health system change
: We hear a lot about interoperability of information technology systems between health f...Waisman director leading early stages of the Wisconsin Institutes for Discovery
But even as architects design the (WID), campus leaders are busy forging its identity....NimbleGen partners with leading researchers
The company has announced a number of limited-access partnerships, opening the door for organizations like Yale Univer...Leading global Big Pharma companies of 2005
I always look forward to writing this particular article with great anticipation! Why, you say? It is part of an annual ritual that I have followed with eagerness as I grew up in the pharmaceutical industry, initiating in my 10 years at Pfizer (way before Pfizer was the juggernaut it is today). At Pfizer, we were all anxious to see the annual company ranking results...Leading cancer institute to install three TomoTherapy systems
The , based at the University of South Florida in Tampa, will install three of TomoThera...Is Diabetes the Leading Cause of Kidney Failure in India
No one knows the answer to this one as we do not have collective data, however diabetes is the number one cause of kidney failure in the United States, accounting for more than 40 percent of the new cases of end-stage renal disease (ESRD)each year. People with ESRD require regular dialysis or a kidney transplant to stay alive. Almost 25% of patients suffering from diabetes will get kidney problem...Misleading Advertisements for Prescription Drugs
In direct-to-consumer advertisements of prescription drugs, statements about drug benefits are often overblown and misleading. "These advertisements rarely quantify the medications' expected benefit; instead, they make an emotional appeal," Dr. Steven Woloshin from Dartmouth Medical School, Hanover, New Hampshire. // Instead of telling the consumer how likely it is that the medicine i...The Effects Of Smoking Misleading
A new study shows that smokers who think that they might be taking a step in the right direction by switching to a “ light “ or “ mild “ cigarette // might not be actually as beneficial as thought . Researchers say the reduction in nicotine is minimal, and in the end, the light or mild cigarette could actually increase a person’s risk for problems. Previous studies have shown that low-yield cigar...Antidepressant Medication Leading To Suicidal Thoughts
The antidepressant Seroxat has been linked to increased suicide attempts among adults and it has been suggested that appropriate warning should be given to doctors and patients regarding this peculiar adverse effect of the drug. // The drug has already been banned for use in children and adolescents due to an increased risk of self-harm. The above study was conducted in a group of 916...