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New treatment option for latent tuberculosis

This release is available in French . Montreal, December 31st, 2008 Patients who are infected with the latent form of tuberculosis (TB) show no symptoms and are not contagious, yet they pose the biggest challenge when it comes to controlling the disease. The latest study by Dr. Dick Menzi...

New Latent TB Drug Saves Lives, Money

Rifampin improved compliance, reduced side effects, saved $10,000 per patient TUESDAY, May 20 (HealthDay News) -- Using the drug Rifampin to treat people with latent tuberculosis saves time, money and lives, new research shows. "We found that using a therapy of four months of Rifa...

Rifampin: Latent TB treatment saves time money and lives

ATS 2008, TORONTOA new way to treat patients with latent tuberculosis (TB), who are infected with TB but without symptoms, can effectively treat it in less than half the time and at a lower cost than the current standard treatment, according to researchers who conducted a multi-center, randomized ...

New chemical can kill latent tuberculosis bacteria

NEW YORK (March 13, 2008) -- Success in the laboratory suggests that a new compound can point the way to preventing active tuberculosis in people infected with the latent form of the bacterium, says a team led by researchers at Weill Cornell Medical College in New York City. A drug with such prope...

High Rates of Latent TB Infection Found in Russian Health Workers

Testing for tuberculosis has revealed that nearly 40% of the doctors in one Russian city have latent infection, with even higher levels// in those who work in TB clinics. The research has been published in PLoS Medicine. TB disease is a growing problem worldwide. Russia is one country where i...

Detecting Latent Tuberculosis Effective With Blood Tests

Italian researchers claim the superiority of blood tests over skin tests for detecting people with latent tuberculosis. //According to them blood tests are effective, reliable and therefore holds promise in detecting latent TB. Though the numerous people with the dormant TB infection never actu...

New Drug Promises Hope In Multiple Drug Resistant And Latent TB Treatment

FAS20013, a tuberculosis drug, currently in the experimental phase has offered hope in the treatment of multiple drug resistant and latent infections as well. The mechanism of action of the new drug is different // than those used for conventional treatment. The drug targets slow growing myco...

Valporic Acid Blocks Latent HIV Replication

Researchers at the University of North Carolina have found that administrating Valporic acid can kill dormant HIV persistent in the infected cells. HAART (Highly Active Antiretroviral Therapy), which is administered to AIDS patients acts by blocking the virus replication and also enhances the immun...

Treating Latent Herpes With Licorice

Most viruses, including herpes, cause both active infections and also hide within the body for long periods of time, causing no immediate infection // but can strike again whenever resistance is lowered. The latent infections thus pose repeated problems for those infected. Based on findings of a...

U.S. Debut: Holistic Health And Beauty From The Rainforest - New Book Reveals Closely Guarded Malaysian Health and Beauty Secrets Introducing the World to Time-Honored Tradition of Ramuan

... down the idea that food possesses "hot" or "cold" values; the terms hot and cold are not specifically associated with temperature but rather indicate latent properties associated with certain dietary items. In order to bring balance to the body, "cold" foods like cucumber and eggplant, and "hot" foods li...
Latent in Medical Technology

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

...uated for the risk of tuberculosis (TB), including latent tuberculosis, prior to initiation of SIMPONI. If ...B is diagnosed, SIMPONI must not be initiated. If latent TB is suspected then the benefit/risk balance should be considered for the following: treatment of latent tuberculosis infection should be initiated prior t...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

...the following: Tuberculosis (TB) or have been near someone who has TB. Doctors will check for TB with a skin test. If a patient has latent (inactive) TB, TB treatment should begin before starting REMICADE. Lived in a region where certain fungal infections like histoplasmosis or co...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

...l advantages, including faster availability, lower incidence and severity of acute graft versus host disease, lower risk of transmitting infections by latent viruses, lack of donor attrition and no risk to the donor. CB is commonly used for pediatric patients; however, it is used less frequently for adults...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

... Active tuberculosis, including reactivation of latent tuberculosis. Patients with tuberculosis have freq...rapulmonary disease. Patients should be tested for latent tuberculosis before CIMZIA use and during therapy. Treatment for latent infection should be initiated prior to CIMZIA use....

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

...atients for tuberculosis risk factors and test for latent tuberculosis infection prior to initiating CIMZIA and during therapy. Initiate treatment of latent tuberculosis infection prior to therapy with CIMZI...ation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course ...

CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients

...atients for tuberculosis risk factors and test for latent tuberculosis infection prior to initiating CIMZIA and during therapy. Initiate treatment of latent tuberculosis infection prior to therapy with CIMZI...ation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course ...

CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients

...atients for tuberculosis risk factors and test for latent tuberculosis infection prior to initiating CIMZIA and during therapy. Initiate treatment of latent tuberculosis infection prior to therapy with CIMZI...ation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course ...

Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment

...ions are controlled. HUMIRA should not be used by patients with active TB or other severe infections such as sepsis and opportunistic infections. If latent tuberculosis is diagnosed, appropriate treatment for latent tuberculosis must be initiated with anti-tuberculosis prophylaxis therapy before starting ...

Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohn's Disease

...atal. Anti-tuberculosis treatment of patients with latent tuberculosis infection reduces the risk of reactiv...atients for tuberculosis risk factors and test for latent tuberculosis infection prior to initiating Cimzia(R) and during therapy. Initiate treatment of latent tuberculosis infection prior to therapy with Cimzi...

Gates Foundation Seeks Proposals for Innovative Global Health Research

...he basis for latency in TB: Unconventional approaches to understanding latent TB infection, with the goal of discovering new ways to identify and eliminate latent infection, and break the cycle of TB transmission. Grant proposals fo...
Latent in Medical Products

biokitHSV-2 Rapid Test

Description:...unological experience and to aid in the diagnosis of HSV associated disease. This assay will not differentiate whether infection is currently in a latent or active state....
Company:Biokit
Latent in Medical Dictionary

Zoster

...ath often ... Zoster : Related Diseases ... Herpes zoster (commonly referred to as "shingles") and postherpetic neuralgia ... Reactivation of latent varicella- zoster virus from dorsal root ganglia is ... Shingles, also known as herpes zoster , gets its name from both Latin and French ....

Tuberculosis

...s. What is tuberculosis ? ... Tuberculosis (TB) is an infection caused by slow-growing bacteria that grow best ... Tuberculosis is either latent or active. ... Tuberculosis (TB) is making a comeback in the United States today - particularly ... Another type of infection is called reacti...

Fluorescein

...type of dye laser as the gain medium, in forensics and serology to detect latent blood stains, and in dye tracing. Fluorescein has an absorption maxim... the eye Fluorescein is useful as a presumptive searching reagent for latent bloodstains. ... Spraying with fluorescein does not affect retrieval of D...

Coccidioidin

...optive transfer of coccidioidin sensitivity to tolerant animals by ... 2. Repeated intradermal coccidioidin testing of reactors with weak or latent ... allergic inflammatory response to coccidioidin need not necessarily be ... Coccidioidin skin test. Definition. The coccidiodin skin te...

Autoimmune hepatitis

...a disease in which the body's immune system attacks liver cells. ... Genetic distinctions between types 1 and 2 autoimmune hepatitis ... latent autoimmune hepatitis triggered during interferon therapy in patients with ... Autoimmune hepatitis was first described in 1950 as a dis...
Latent in Biological News

Tuberculosis drug shows promise against latent bacteria

A new study has shown that an investigational drug (R207910, currently in clinical trials against multi-drug resistant tuberculosis strains) is quite effective at killing latent bacteria. This revelation suggests that R207910 may lead to improved and shortened treatments for this globally prevale...

Synthetic peptide targets latent papilloma virus infections

While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected and at constant risk of genital wa...

A simple feedback resistor switch keeps latent HIV from awakening

Upon entering a cell, a virus often becomes dormant, turning off its genes and laying low until awakened by som e trigger from its environment. When that trigger is pulled, the virus quickly ramps up production of proteins through built-in positive-feedback loops that turn up gene transcription. (I...

Treating populations infected with HIV and latent TB could speed the emergence of drug-resistant TB

In 2005, 46 regional Ministers of Health in Africa declared that a dramatic rise in tuberculosis (TB) cases was cause for emergency. In some African countries, annual TB case notifications have increased as much as four-fold over the past 15 years. The main culprit? The emergence of HIV. When indiv...

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

An experimental tuberculosis drug may be effective against not only multi drug-resistant forms of the disease but could also be the first compound to treat the latent stage of infection as well. Researchers report their results today at the 2006 ASM Biodefense Research Meeting. "The class of wh...

How A Latent Virus Eludes Immune Defenses

For a virus to survive, it must elude the ever vigilant immune sentinels of its host. A latent virus can escape immune detection if it resides in nondividing cells and doesn’t produce any proteins. No viral proteins means no red flags for immune cells. If the virus targets one of the many cell type...

AGU journal highlights -- Aug. 6, 2009

...ibed land cover reflecting conditions in 1870 and in 1992. The authors find that in all models, LCC has a statistically significant regional effect on latent heat flux and near-surface temperature. Furthermore, they find that LCC affect temperature only in the region where the land cover change took place, ...

'Shock and kill' research gives new hope for HIV-1 eradication

... latent HIV genes can be 'smoked out' of human cells. The so-called 'shock and kill' technique, described in a preclinical study in BioMed Central's open acce...

Preclinical work shows how one gene causes severe mental retardation

... findings suggest that brain cells in Angelman syndrome patients maintain a latent ability to express plasticity. We are now collaborating to find a way to tap into this latent plasticity, as this could offer a treatment, or even a cure, for Angelman s...

Some vocal-mimicking animals, particularly parrots, can move to a musical beat

...gh for a bird to keep a beat, although the researchers aren't yet certain why some parrots can dance and not others. It may be that all parrots have a latent capacity, but need certain experiences or social motivation, according to Schachner. Schachner says that these birds do not seem to move in synchro...

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Latent in Biological Technology

ChemImage Works to Improve Existing Methods of Imaging Untreated Fingerprints on Paper Substrates

...nfigurations resulting in the enhancement of more ridge detail of untreated latent prints on paper. "The results are very promising," said John Belechak,...vious publications demonstrates a noteworthy step forward in the science of latent print examination." The CONDOR Hyperspectral Imaging System utilizes l...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... Active tuberculosis, including reactivation of latent tuberculosis. Patients with tuberculosis have fre...apulmonary disease. Patients should be tested for latent tuberculosis before CIMZIA use and during therapy. Treatment for latent infection should be initiated prior to CIMZIA use....

Astellas Receives FDA Approval for Use of Prograf(R) (Tacrolimus) in Conjunction With Mycophenolate Mofetil (MMF) in Kidney Transplant Recipients

...rior reversible encephalopathy syndrome (PRES). If PRES is suspected or diagnosed, immediate reduction of immunosuppression is advised. Activation of latent viral infections, including BK virus-associated nephropathy and JC virus-associated progressive multifocal leukoencephalopathy (PML), has also been re...

Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... evaluated for the risk of tuberculosis, including latent tuberculosis, prior to initiation of SIMPONI. Treatment of latent tuberculosis infection should be initiated prior t...atment, including patients who tested negative for latent tuberculosis infections. The use of TNF blocking a...

aTyr Pharma to Present at ChinaBio(R) Investor Forum in Hong Kong

...ities, roles and functions for this ancient class of enzymes and reported the first evidence that fragments and splice variants of these proteins have latent extracellular activities distinct from their intracellular roles in protein synthesis. With a wide variety of cell signaling activities, this class o...

Dr. James Cai Joins aTyr Pharma to Drive Clinical Development in Asia

...ities, roles and functions for this ancient class of enzymes and reported the first evidence that fragments and splice variants of these proteins have latent extracellular activities distinct from their intracellular roles in protein synthesis. With a wide variety of cell signaling activities, this class o...

Sirion Therapeutics New Drug Application for Ganciclovir is Accepted for Review by the FDA for the Treatment of Ocular Herpes

...utbreaks, with 20,000 primary cases of ocular herpes diagnosed in the U.S. each year. After the primary infection, ocular HSV typically becomes latent until triggers such as stress, UV radiation, and hormonal changes reactivate the virus and cause recurrent outbreaks. Those recurrences account for an...

New Biologic STELARA(TM) Receives Approval in Europe for Treatment of Moderate to Severe Plaque Psoriasis

...Important Safety Information STELARA is a selective immunosuppressant and may have the potential to increase the risk of infections and reactivate latent infections. Serious infections have been observed in patients receiving STELARA in clinical trials. Do not start STELARA during an active infection....

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

...atal. Anti-tuberculosis treatment of patients with latent tuberculosis infection reduces the risk of reactiv...atients for tuberculosis risk factors and test for latent tuberculosis infection prior to initiating CIMZI... (R) and during therapy. Initiate treatment of latent tuberculosis infection prior to therapy with CIM...

The Plasmodium vivax genome provides new routes and challenges in the global fight against malaria

... P falciparum . Furthermore, the larger public health problem in controlling P vivax lies in the fact that this parasite can reside in the liver in latent form and, months or years later, when the primary infection has been overcome, can cause clinical relapses. P vivax therefore has serious consequenc...
Latent in Biological Definition

Virus classification

...iroid 1 Family Avsunviroidae Genus Avsunviroid ; type species: Avocado sunblotch viroid Genus Pelamoviroid ; type species: Peach latent mosaic viroid Satellites Satellite viruses Single-stranded RNA satellite viruses Sugroup 1: Chronic bee-paralysis satellite vir...
Latent in Biological Dictionary

RNA virus

...his disparate group of viruses , providing for the first time a single resource reviewing dsRNA ... Double-stranded RNA viruses . Retroviruses. latent Viruses . Lysogeny. Transduction. Viruses ... Either DNA or RNA , never both. DNA viruses can be further divided into ... Information about ...

Prophage

.... A temperate phage integrated into the host chromosome or existing as an extrachromosomal plasmid. This is a latent... prophage ( ) n. The latent form of a bacteriophage in which the viral genes are incorporated into the bacterial chromosomes without causing disruption Prophage content ...

N Terminus

... sequences is to put the C-terminal end on the right and write the sequence from N - to C- terminus . The N terminus prevents folding to the latent state ... Together, these data suggest that the N terminus of tengpin is not required for ... Its N terminus is tyrosine-sulfated, as are m...

Melting temperature

... temperature of some common metals and alloys ... latent Heat of Melting of some common Materials The latent heat of fusion when ... Melting and boiling point temperatures , latent evaporation and melting heat of some common subs...

Lytic cycle

...roduction (the lytic Viruses can multiply by two alternate mechanisms: the lytic or the lysogenic cycle . ... the virus to break out of its latent state and enter the lytic cycle . ... Lytic cycle antigens were predominantly derived from structural proteins of the ... The lytic c...
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