Epilepsy Drug Valproate and Lamotrigine Linked To Malformed Fetus

In a study in the March issue of Neurology, the epilepsy drug Valproate has been linked to malformation of fetus //when prescribed to pregnant ladies. For pregnant women with epileptic seizures, often the drug Valproate is prescribed. The new study shows that women who took the drug in their ...

FDA Approves Lamictal(R)XR(TM); An Extended-Release Once-Daily, New Generation Treatment for Epilepsy

...nt of the stomach, leading to a gradual release of lamotrigine into the bloodstream. Safety Information ...have occurred. In particular, the name Lamictal or lamotrigine can be confused with the names of other commonly u...ictal XR if they have had an allergic reaction to lamotrigine or to any of the inactive ingredients. Com...

FDA Approves Lamictal(R) ODT(TM) Orally Disintegrating Tablets

...s involving Lamictal have occurred. In particular, the name Lamictal or lamotrigine can be confused with the names of other commonly used medications. Medicati...ake Lamictal or Lamictal ODT if they have had an allergic reaction to lamotrigine or to any of the inactive ingredients. Common side effects include ...

For Bipolar Depression, Surveyed Experts Indicate That Current and Emerging Therapies Have No Advantage Over Seroquel in Decreasing the Severity of Symptoms

... clinical gold standard for bipolar depression was lamotrigine (GlaxoSmithKline's Lamictal, generics). Based on available data and expert opinion, lamotrigine will retain gold standard status through 2017. Whi...Owing to its efficacy and tolerability advantages, lamotrigine edged out Seroquel, its closest competitor, to bec...

Epilepsy Drug Impairs Baby's Intelligence

... epilepsy medications during pregnancy, including valproate, carbamazapine, lamotrigine and phenytoin. The researchers plan to assess the children periodically...e other medications. The average IQ for children exposed in the womb to lamotrigine was 101, for phenytoin it was 99, and for carbamazepine it was 98. Children...

New research suggests common anti-seizure medications may increase risk of cardiovascular problems

... patients taking either one of those two drugs who were being switched over to one of two newer anti-seizure drugs which do not widely affect enzymes lamotrigine (Lamictal) or levetiracetam (Keppra). The goal was to determine if the change affected the patients' cholesterol levels and other key markers of cardi...

Mylan Receives Final FDA Approvals for Generic Versions of Lamictal(R) Tablets and Lamictal(R) CD

...heir Abbreviated New Drug Applications (ANDAs) for lamotrigine Tablets. Genpharm also received final FDA approval for its ANDA for a separate lamotrigine product, lamotrigine Tablets Chewable Dispersible (CD). Mylan Pha...

Epilepsy Drug May Raise Autism Risk in Offspring

...orders among the children of women who had taken another anti-seizure drug, lamotrigine (brand name Lamictal), while pregnant. Drugs for this condition have enc...lamotrigine, one to phenytoid (Dilantin among other brand names) and one to lamotrigine alone. Just over 6.3 percent of children exposed to valproate alone have...

FDA Advisers Don't Back 'Black Box' Warning for Epilepsy Drugs

...FDA were: Carbamazepine (marketed as Carbatrol, Equetro, Tegretol, Tegretol XR), Felbamate (marketed as Felbatol), Gabapentin (marketed as Neurontin), lamotrigine (marketed as Lamictal), Levetiracetam (marketed as Keppra), Oxcarbazepine (marketed as Trileptal), Pregabalin (marketed as Lyrica), Tiagabine (markete...

FDA Advisers Don't Back Epilepsy Drug Warnings

...FDA were: Carbamazepine (marketed as Carbatrol, Equetro, Tegretol, Tegretol XR), Felbamate (marketed as Felbatol), Gabapentin (marketed as Neurontin), lamotrigine (marketed as Lamictal), Levetiracetam (marketed as Keppra), Oxcarbazepine (marketed as Trileptal), Pregabalin (marketed as Lyrica), Tiagabine (markete...

Lamotrigine in Medical Technology

New Data Shows Once a Day Lamictal XR is Effective in Treating Patients with Partial Seizures

...immediate release, a 2 week treatment phase with Lamictal XR and a 1 week treatment phase with Lamictal immediate release. The study outcomes included lamotrigine pharmacokinetics upon conversion and seizure frequency during each treatment phase. Results showed the steady state trough concentrations for Lamict...

Lamotrigine in Biological News

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

...pproval by the Food and Drug Administration (FDA) and wide dissemination to patients. These have included the anticonvulsants valproate (Depakote) and lamotrigine (Lamictal), and the atypical antipsychotic quetiapine (Seroquel). These agents have vastly enlarged our treatment armamentarium and provided new optio...

Lamotrigine in Biological Technology

Mylan Announces Tentative FDA Approval for Lamotrigine Tablets

PITTSBURGH, Dec. 12 /PRNewswire-FirstCall/ -- Mylan Inc. (NYSE: MYL ) today announced that Mylan Pharmaceuticals Inc. has received tentative approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Lamotrigine Tablets, 25 mg, 100 mg, 150 mg...

Multiple Vimpat(R) (lacosamide) Studies Presented at American Epilepsy Society Annual Meeting

... study entry, mainly carbamazepine (35.2 percent), lamotrigine (31.2 percent), levetiracetam (29.0 percent), valp... 400 mg/day vs. 21.7 percent with placebo) -- lamotrigine (33.3 percent vs. 18.3 percent) -- Levetiracet...400 mg/day vs. 26.4 percent placebo) -- lamotrigine (34.2 percent vs. 19.0 percent) -- Levetiracet...