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LOD in Biological Technology

Determination of Acepromazine and its Major Metabolite in Equine Serum by LC-MS/MS using the Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

...promazine in horse serum. Acepromazine was detected in horse serum for up to 2 hr after dosing whereas its metabolite was detected for up to 6 hr. The lod achieved for acepromazine in horse serum was determined to be 0.5 ng/mL, while the LOQ for its metabolite was 0.5 ng/mL. Acknowledgments ...

Trace Analysis Optimizing Sensitivity Finnigan Surveyor PDA Detector

...entration that can be detected. If it is possible to increase the signal with no significant increase in the noise level, substantial decreases in the lod will be seen which will allow better accuracy and precision at the limit of quantitation (LOQ). Noise is made up of two components: short-term and lon...

Sensitivity and Quantitation using a Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

... the analyte (m/z 274 + 281) and the internal standard (m/z 279 + 286). The lod was determined to be 500 fg for alprazolam, with a signal-tonoise of 5 to 1...olam. The CV was around 5-7% except near the LOQ, where the CV was 15%. The lod and LOQ for alprazolam is 500 fg and 1 pg, respectively whereas that for te...

SNPs Powerful Tools for Association Studies

...the phenotype being studied. lod scores are used to measure the degree of linkage ...locus and a putative disease locus. The higher the lod score, the more likely the two are linked. In humans, a lod score > 3 is often considered significant and a...

Fast Analysis of Phenoxyacetic and Phenoxypropionic Herbicides in Vegetable Matrix by Negative Ion Electrospray LC/MS/MS

...ellent linearity for all the herbicides from 0.1 to 5 ppb as shown for dichlorprop in Figure 4. The developed MRM method is also very sensitive with a lod of 0.1 ppb for all the pesticides under the described instrument conditions. Conclusion This ...

Analysis Of Chloramphenicol by Negative Ion Electrospray LC/MS/MS

Z. Yang, Varian, Inc. Introduction Chloramphenicol (CAP) is a potent, broad-spectrum antibiotic and potential carcinogen used in humans only at therapeutic doses for treatment of serious infections. Its use in meatproducing animals, food producing insects, aquacultu...

Detection of Alprazolam and Temazepam in a Bovine Plasma Matrix Using the Varian 500-MS Ion Trap Mass Spectrometer

...column). The Signal-to-Noise (S/N P-P) ratio of temazepam in the spiked matrix was determined to be 16:1 at 500 fg on column. The lod (limit of detection) values for the three different types of matrix environments are summarized in Table 1. A calibration curve of Alprazolam in a bef...

Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System

...nt over the 7-in-1 experiment performed on the API III+. The remaining five compounds were all detected on the API 3000 LC/MS/MS System well above the lod at the 24 hour sampling time. Conclusions These experiments demonstrate the feasibility of using shorter dwell times...

Determination of Polar Organophosphorus Pesticides in Aqueous Samples by Direct Injection Using HPLC/MS/MS

...are directly injected onto a LC-MS system. By direct injection of 1 ml, the lod (S/N = 3) varied between 0.01 and 0.03 μg/l depending on the analyte and applied resolution. It may be possible to further lower the lod by injection of even larger volumes, directly on the analytical column or b...

The Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) by LC/MS/MS Using an Atmospheric Pressure Photoionization Source

...gure 1). Under optimized LC/MS/MS conditions for both reversed phase and normal phase chromatographic conditions, the performance, linearity and lod levels were determined. The most abundant single positive transition for each PAH compound was used to construct an +MRM method. Concentrations ...
LOD in Biological Dictionary

LOD score

... (Redirected from lod score ) Jump to: navigation, search ... 3 lod score method for estimating recombination frequency. 4 Recombination frequency ... lod Score Method of Estimating Linkage Distances .....

Linkage group

...the group ... For the purpose of finding linkage groups , MAPMAKER considers linkage transitive. ... 4> group Linkage Groups at min lod 3.00, max Distance 50.0 ... We assigned zebrafish genetic linkage groups to specific chromosomes using ... Table 2 Chromosomes and Linkage ...

Linkage

...rices. Free shipping on all items. Linkage and Distored Mendelian Ratios. Estimating Distances Between Genes. Estimating Linkage From Three ... lod Score Method of Estimating Linkage Distances ... Most linkage programs on the market today force you to use proprietary macros, and work ... wi...
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