Determination of Acepromazine and its Major Metabolite in Equine Serum by LC-MS/MS using the Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer
...promazine in horse serum. Acepromazine was detected in horse serum for up to 2 hr after dosing whereas its metabolite was detected for up to 6 hr. The lod
achieved for acepromazine in horse serum was determined to be 0.5 ng/mL, while the LOQ for its metabolite was 0.5 ng/mL.
Trace Analysis Optimizing Sensitivity Finnigan Surveyor PDA Detector
...entration that can be detected. If it is possible to increase the signal with no significant increase in the noise level, substantial decreases in the lod
will be seen which will allow better accuracy and precision at the limit of quantitation (LOQ). Noise is made up of two components: short-term and lon...
Sensitivity and Quantitation using a Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer
... the analyte (m/z 274 + 281) and the internal standard (m/z 279 + 286). The lod
was determined to be 500 fg for alprazolam, with a signal-tonoise of 5 to 1...olam. The CV was around 5-7% except near the LOQ, where the CV was 15%. The lod
and LOQ for alprazolam is 500 fg and 1 pg, respectively whereas that for te...
SNPs Powerful Tools for Association Studies
...the phenotype being studied.
scores are used to measure the degree of linkage ...locus and a putative disease locus. The higher the lod
score, the more likely the two are linked. In humans, a lod
score > 3 is often considered significant and a...
Fast Analysis of Phenoxyacetic and Phenoxypropionic Herbicides in Vegetable Matrix by Negative Ion Electrospray LC/MS/MS
...ellent linearity for all the herbicides from 0.1 to 5 ppb as shown for dichlorprop in Figure 4. The developed MRM method is also very sensitive with a lod
of 0.1 ppb for all the pesticides under the described instrument conditions.
Analysis Of Chloramphenicol by Negative Ion Electrospray LC/MS/MS
Z. Yang, Varian, Inc.
Chloramphenicol (CAP) is a potent, broad-spectrum antibiotic and potential carcinogen used in humans only at therapeutic doses for treatment of serious infections. Its use in meatproducing animals, food producing insects, aquacultu...
Detection of Alprazolam and Temazepam in a Bovine Plasma Matrix Using the Varian 500-MS Ion Trap Mass Spectrometer
...column). The Signal-to-Noise (S/N P-P) ratio of temazepam in the spiked matrix was determined to be 16:1 at 500 fg on column.
(limit of detection) values for the three different types of matrix environments are summarized in Table 1. A calibration curve of Alprazolam in a bef...
Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System
...nt over the 7-in-1 experiment performed on the API III+. The remaining five compounds were all detected on the API 3000 LC/MS/MS System well above the lod
at the 24 hour sampling time.
These experiments demonstrate the feasibility of using shorter dwell times...
Determination of Polar Organophosphorus Pesticides in Aqueous Samples by Direct Injection Using HPLC/MS/MS
...are directly injected onto a LC-MS system. By direct injection of 1 ml, the lod
(S/N = 3) varied between 0.01 and 0.03 μg/l depending on the analyte and applied resolution. It may be possible to further lower the lod
by injection of even larger volumes, directly on the analytical column or b...
The Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) by LC/MS/MS Using
an Atmospheric Pressure Photoionization Source
...gure 1). Under
optimized LC/MS/MS conditions for both reversed phase and normal phase chromatographic
conditions, the performance, linearity and lod
levels were determined. The most
abundant single positive transition for each PAH compound was used to construct
an +MRM method. Concentrations ...
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score method for estimating recombination frequency. 4 Recombination frequency ... lod
Score Method of Estimating Linkage Distances .....
...the group ... For the purpose of finding linkage groups , MAPMAKER considers linkage transitive. ... 4> group Linkage Groups at min lod
3.00, max Distance 50.0 ... We assigned zebrafish genetic linkage groups to specific chromosomes using ... Table 2 Chromosomes and Linkage ...
...rices. Free shipping on all items. Linkage and Distored Mendelian Ratios. Estimating Distances Between Genes. Estimating Linkage From Three ... lod
Score Method of Estimating Linkage Distances ... Most linkage programs on the market today force you to use proprietary macros, and work ... wi...