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LHRH in Medical News

Immune Boost With LHRH To Help Cancer And Transplant Patients

A simple technique to rejuvenate the immune system, to increase its output and enhance response of the T cells has been developed by Australian scientists. This could help cancer and HIV patients fight their disease// better. It is also hoped to reduce the risk of rejection in transplant patient...

Watson Pharmaceuticals Receives a Complete Response Letter for Its 24-Week Formulation of TRELSTAR(R) (triptorelin pamoate) NDA from US FDA

...ion In clinical trials, the most common adverse events occurring in patients were hot flushes, skeletal pain, impotence and headache. As with all lhrh agonists, triptorelin causes an initial transient increase in testosterone levels and may initiate or worsen symptoms during this transient period. Ra...

Interviewed Experts Expect Taxotere to Increase Overall Survival More Than Other Drugs, Including Lupron Depot, in Stage III Prostate Cancer

...te cancer. Clinical data and the opinions of interviewed thought leaders indicate that Sanofi-Aventis's Taxotere has advantages in this attribute over lhrh agonists, including Abbott's Lupron Depot, the sales-leading agent in the market. The new report entitled Stage III Prostate Cancer: Oncologists...

Ferring Pharmaceuticals Announces Immediate Availability of Degarelix for the Treatment of Advanced Prostate Cancer

...llicle-stimulating hormone (FSH), and subsequently, testosterone levels.(4) Degarelix also reduces levels of prostate-specific antigen (PSA). Unlike lhrh agonists, such as leuprolide, an established treatment for prostate cancer, degarelix does not induce an initial testosterone surge. Degarelix is adm...

Watson Announces the NDA for a 6-Month Formulation of TRELSTAR(R) Accepted for Filing by FDA for the Treatment of Advanced Prostate Cancer

...mation In clinical trials, the most common adverse events occurring in patients were hot flushes, skeletal pain, impotence and headache. As with all lhrh agonists, triptorelin causes an initial transient increase in testosterone levels and may initiate or worsen symptoms during this transient period. Ra...

AEterna Zentaris Announces First Patient Dosing for Safety Trial of Phase 3 Program with Cetrorelix in Benign Prostatic Hyperplasia

...dverse events. About Cetrorelix Cetrorelix is part of AEterna Zentaris' lhrh antagonist therapeutic approach that has demonstrated in Phase 2 studies to...Cetrorelix acetate is marketed under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of in vitro fertilization p...

Did Medicare Reimbursement Changes Affect Prostate Cancer Treatment?

...ame thing," he said. The use of only one of the lhrh agonists -- triptorelin -- increased after the Med...tments are equal, the choice is the patient's." lhrh agonists render the testicles as inactive as surgi...at "changing a recommendation to a patient from an lhrh agonist to surgical castration solely for economic...

Indevus Pharmaceuticals Licenses European Rights for VANTAS(R) to Orion Corporation

...d. In Europe, prostate cancer is the fourth most commonly diagnosed cancer with an estimated 242,960 men diagnosed in 2006. According to IMS data, the lhrh market in Europe is over $1 Billion. About Indevus Pharmaceuticals, Inc. Indevus Pharmaceuticals, Inc. is a specialty pharmaceutical company engag...

A Fresh Alternative to Painful Chemotherapy Developed in UK

... for the patient. Now researchers say that lhrh agonists like the drug Zoladex switch off the ovar...trols sex hormones in both men and women. Thus, an lhrh agonist serves in a manner similar to lhrh to control the same sex hormones. Four Lon...
LHRH in Medical Technology

AEterna Zentaris Reaches 2nd Stage of Patient Recruitment for Phase 2 Trial in Ovarian Cancer with the Innovative LHRH Receptor Targeted Conjugate, AEZS-108

QUEBEC CITY, Oct. 2 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today reported that it has entered the second stage of patient recruitment for its Phase 2 trial in ovarian cancer with A...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... Study results : EP-100 consists of an lhrh receptor-targeting ligand conjugated to a novel me...as tested in vitro and in vivo for activity in lhrh receptor over-expressing and multi-drug resistant ...VCAR-3). As a negative control, the study utilized lhrh receptor negative SKOV-3 ovarian cancer cells. In ...

Watson Announces Positive Data for Its New Investigational Products for Benign Prostatic Hyperplasia and Overactive Bladder

...ature. In clinical trials, the most common adverse events occurring in patients were hot flushes, skeletal pain, impotence and headache. As with all lhrh agonists, triptorelin causes an initial transient increase in testosterone levels and may initiate or worsen symptoms during this transient period. Ra...

Access Pharmaceuticals Demonstrates Ability to Significantly Reduce Glucose Levels in Pre-clinical Testing of Cobalamin(TM) Oral Insulin

... would develop in partnership with a collaborator, we believe that our Cobalamin technology has applicability to a variety of cancer products, such as lhrh which are part of our developing cancer and supportive care franchise." About Access: Access Pharmaceuticals, Inc. is an emerging biopharmaceutica...

AEterna Zentaris Reports Positive Results with Cetrorelix in BPH for Japanese Phase 2a Trial

...esource, cetrorelix is currently the most advanced lhrh antagonist in development for the treatment of BPH...trorelix Cetrorelix is part of AEterna Zentaris' lhrh antagonist therapeutic approach. This peptide-base...keted under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of...

Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session

...ally, once daily, to chemotherapy-naive patients with castration refractory prostate cancer (CRPC), who had progressive disease despite treatment with lhrh analogues and multiple other hormonal therapies, including antiandrogens, diethylstilboestrol and dexamethasone. To date a total of 38 patients have b...

Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at AUA Annual Meeting

...ally, once daily, to chemotherapy-naive patients with castration refractory prostate cancer (CRPC), who had progressive disease despite treatment with lhrh analogues and multiple other hormonal therapies, including antiandrogens, diethylstilboestrol and dexamethasone. To date a total of 38 patients have b...

AEterna Zentaris' Partner, Spectrum, Discloses Detailed Phase 2 Data for Ozarelix, in BPH at Annual AUA Meeting

...Eterna Zentaris. "With cetrorelix in an ongoing Phase 3 program and ozarelix completing a Phase 2b trial this year, we are fortunate to be leading the lhrh antagonist class with two very promising compounds for the treatment of BPH." Details The abstract #93629 (Poster #1552) titled, "The efficacy ...

Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ASCO Annual Meeting

...rally, once daily, to chemotherapy-naive patients with castration resistant prostate cancer (CRPC), who had progressive disease despite treatment with lhrh analogues and multiple other hormonal therapies, including antiandrogens, diethylstilboestrol and dexamethasone. To date, a total of 42 patients have ...

Phase III Clinical Trial with 4-Month Long-Acting Formulation of Triptorelin: Ipsen Decides Not to Perform Further Administration

...one secreted in a pulsatile fashion. Upon binding to its pituitary receptor lhrh triggers the release of luteinizing hormone, a key factor for the regulation of reproductive function. Continuous administration of exogenous lhrh or its agonists such as triptorelin leads to a rapid desensitization of its...
LHRH in Medical Dictionary

Hypogonadism

... can ... Hypogonadism . Hypopituitarism. Hypothyroidism. Non-Functioning Tumors ... Hypogonadotropic hypogonadism - Idiopathic gonadotropin or lhrh deficiency or ... A look at hypogonadism , a hormonal abnormality that often results in male infertility. ... Hypogonadism . Anti Sperm Antibo...
LHRH in Biological News

Olfactory system detects pheromones that control reproduction

...size luteinizing hormone releasing hormone (LHRH). lhrh controls the onset of puberty. In females it also ...roduction. "One of the classical dogmas is that lhrh neurons receive inputs from the vomeronasal system...the vomeronasal system are directly connected with lhrh neurons, and thus carry the modulatory effect of p...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...Breast Cancer and Metastases with a Combination of lhrh and Lytic Peptide, Hecate, bound to Iron Oxide Nan...urfaces and created a molecular complex, combining lhrh with a 10 nm nanoparticle ?superparamagnetic irono...surface was covered with alternating "sun rays" of lhrh and Hecate. In the other, the nanoparticle was bou...
LHRH in Biological Technology

AEterna Zentaris Reaches 2nd Stage of Patient Recruitment for Phase 2 Trial in Endometrial Cancer with the Innovative LHRH Receptor Targeted Conjugate, AEZS-108

QUEBEC CITY, Nov. 3 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today reported that it has entered the second stage of patient recruitment for its Phase 2 trial in endometrial cancer wi...

New Report Just Published: World Prostate Cancer Therapeutics Market Report

...herapy II-32 Medical Hormone Therapy II-32 lhrh Analogs II-33 Dose of lhrh Agonists for Advance Prostate Carcinoma Treatment ...s III-48 Overview III-48 Anti-Androgen and lhrh Analogs Drive the French Market III-48 Current...

AEterna Zentaris to Report Data from Safety Study of Phase 3 Program in Benign Prostatic Hyperplasia with Cetrorelix Ahead of Schedule

... Andrew Schally, currently of the U.S. Veterans Administration in Miami. Cetrorelix acetate is marketed under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of in vitro fertilization programs (controlled ovulation stimulation/assisted reproductive technologie...

AEterna Zentaris Opens Extended Study for Cetrorelix in Benign Prostatic Hyperplasia

... Andrew Schally, currently of the U.S. Veterans Administration in Miami. Cetrorelix acetate is marketed under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of in vitro fertilization programs (controlled ovulation stimulation/assisted reproductive technologie...

AEterna Zentaris Presents Data Supporting Evaluation of AEZS-108 in Prostate Cancer at ASCO Meeting

...ida. The poster (#5163) entitled, "Expression of lhrh receptors in prostate cancer cells prior to therap... following castration, or following treatment with lhrh agonists," S. Liu, A. V. Schally, S. Xiong, R. Cot...e (LHRH) receptors following prolonged exposure to lhrh agonists. "Results presented are important for t...

AEterna Zentaris to Present Data Supporting Evaluation of AEZS-108 in Prostate Cancer at Upcoming ASCO Meeting

...n prostate cancer specimens after prolonged use of lhrh agonists; these data provide further support to th... Sunday, May 31, 2009: # 5103: Expression of lhrh receptors in prostate cancer cells prior to therap... following castration, or following treatment with lhrh agonists Lead Author: Stephen Liu, MD Poster S...

AEterna Zentaris and Sanofi-Aventis Sign a Development, Commercialization and Licensing Agreement for Cetrorelix in Benign Prostatic Hyperplasia

... Andrew Schally, currently of the U.S. Veterans Administration in Miami. Cetrorelix acetate is marketed under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of in vitro fertilization programs (controlled ovulation stimulation/assisted reproductive technologie...

AEterna Zentaris Completes Patient Recruitment for Second Efficacy Trial of its Phase 3 Program with Cetrorelix in Benign Prostatic Hyperplasia

... Andrew Schally, currently of the U.S. Veterans Administration in Miami. Cetrorelix acetate is marketed under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of in vitro fertilization programs (controlled ovulation stimulation/assisted reproductive technologie...

AEterna Zentaris: Article on Phase 2 Trial with Cetrorelix in BPH to be Published in European Urology Journal

...nging Phase 2 study of subcutaneously administered lhrh antagonist cetrorelix in patients with symptomatic...trorelix Cetrorelix is part of AEterna Zentaris' lhrh antagonist therapeutic approach that has demonstra...keted under the brand name Cetrotide(R), the first lhrh antagonist approved for therapeutic use as part of...

FDA Approves MIXJECT(TM), a Convenient, Easy-to-Use Drug Delivery System For Watson Pharmaceutical's TRELSTAR(R) DEPOT and TRELSTAR(R) LA

...mation In clinical trials, the most common adverse events occurring in patients were hot flushes, skeletal pain, impotence and headache. As with all lhrh agonists, triptorelin causes an initial transient increase in testosterone levels and may initiate or worsen symptoms during this transient period. Ra...
LHRH in Biological Dictionary

Complementary RNA

... encoded by angiotensin II complementary RNA does not interfere with angiotensin II action. ... decapeptide encoded by an RNA complementary to lhrh mRNA. ... ...
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