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LEADseeker in Biological Technology

Integration of the LEADseeker Multimodality Imaging System with automated plate loading and incubation using Overlord Instrument software

Key words: LEADseeker • imagin g • automatio n • integratio n The LEADseeker™ Multimodality Imaging System is a CCD-based optical imaging instrument that efficiently detects and quantitates light from a range of radiometric, lum...

Development of a CRF1 neuropeptide receptor binding assay using LEADseeker Multimodality Imaging System

Key words: CRF 1 • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads In the mammalian brain, the corticotrophin-releasing factor (CRF) system comprises four CRF-related peptides (CRF and urocortin 1, 2, and 3...

Development of an adrenergic α2a receptor binding assay using the LEADseeker Multimodality Imaging System

Key words: α 2c receptor • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads The α 2 -adrenergic receptors are G protein-coupled receptors that play a key role in the control of numerous physiol...

The development of a serotonin 5-HT2C receptor-binding assay using the LEADseeker Multimodality Imaging System

Key words: serotonin • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads In mammals, serotonin (5-hydroxytryptamine, 5-HT) is a regulator of neural transmission which induces its biological effect by binding to ...

The development of a somatostatin sst4 receptor-binding assay using the LEADseeker Multimodality Imaging System

Key words: somatostatin • receptor binding assay • LEADseeker • SPA Imaging Beads Somatostatin (SS) is a neurotransmitter/hormone with a wide range of biological actions (1–3) and a reduction in cortical SS levels has been re...

Development of an NK2 neuropeptide receptor binding assay using LEADseeker Multimodality Imaging System

Key words: NK2 • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads Neurokinins, also known as tackykinins, are a family of small neuropeptides. Members of this family include peptides, substance P (SP), neurokin...

Use of BRET2 luminescence cell-based assays with LEADseeker Multimodality Imaging System

Key words: luminescence • BRET 2 • LEADseeker • DeepBlueC• cell-based assays Competitive pressure is forcing organizations to continually increase screening throughput. Yet accuracy and sensitivity remain vital concerns, par...

Use of the HitHunter EFC Chemiluminescent Detection Kits with LEADseeker Multimodality Imaging System

Key words: EFC chemiluminescence • HitHunter • LEADseeker Competitive pressure is forcing organizations to continually increase screening throughput. Yet accuracy and sensitivity remain vital concerns, particularly for common screens such...

Performance of fluorescent dyes with LEADseeker Multimodality Imaging System

Key words: fluorescence • LEADseeker • Cy • Alexa Fluor • TAMRA • Brij Flexible and scalable uHTS programs demand that organizations be able to select the most appropriate or cost-effective fluorescent reagents for t...

Development of a histamine H1 receptor binding assay using the LEADseeker Multimodality Imaging System

Key words: H 1 receptor • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads Histamine is a biogenic amine that plays important pathophysiological roles in central and peripheral tissues. Generally released from stimul...

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LEADseeker in Biological Products

Wheat Germ Agglutinin (WGA) PS SPA Imaging Bead from GE Healthcare, formerly Amersham Biosciences

Description:... Wheat Germ Agglutinin (WGA) PS SPA Imaging Bead, 2 g. Category: leadseeker Beads....
Company:GE Healthcare, formerly Amersham Biosciences
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(Date:11/25/2009)...matology (ASH) is pleased to recognize the followi...bstracts in the categories of undergraduate studen...ysician, and post-doctoral,fellow. Merit Award wi...g,travel reimbursement. , The 2009 Merit Award ...imberly Fan , Donor Dendritic Cells Home to Lymph...
(Date:11/25/2009)... , An innovative treatment for HIV patients dev...ers has passed its first clinical trial with flyin...stomized for each individual patient, and was deve...e of the MUHC in collaboration with Dr. R. Skaly f...ade for the individual patient an "haute couture"...
(Date:11/25/2009)...atients with liver lesions, researchers find , ...ding the drug cetuximab to neoadjuvant chemotherap...ul surgery in colorectal cancer patients with inop...ests. , , Tumors spread to other parts of the ... cancer. Most commonly, the cancer spreads to the ...
Breaking Medicine News(10 mins):Health News:dazzlesmile Sues Epic Advertising and Jesse Willms 2Health News:Lung Cancer Alliance-California Releases 2nd Annual State-Specific Report Card On Lung Cancer 2Health News:ASH announces 2009 Merit Award winners 2Health News:Tailor-made HIV/AIDS treatment closer to reality 2Health News:Cetuximab Helps Treat Colorectal Cancer 2
(Date:11/23/2009)...e of day matters to forest trees dealing with drou...ch team led by Professor Malcolm Campbell, Univers...search and colleagues in the department of cell an...Capitalizing on their previous work to decode the ...ned how poplar trees use their 45,000 genes to res...
(Date:11/23/2009)...ipants gathered this week for the seventh annual N...ce. This year,s topic, "Synthetic Biology," brough...archers to explore the engineering, scientific, an...synthetic biology. , Bonnie L. Bassler, professo... this year,s conference chair, challenged the atte...
(Date:11/23/2009)...s "incontrovertible evidence" that the volcanic su...t 73,000 years ago deforested much of central Indi...s report. , The volcano ejected an estimated 800...ing a crater (now the world,s largest volcanic lak...ide. Ash from the event has been found in India, t...
Breaking Biology News(10 mins):Time of day matters to thirsty trees, U of T researcher discovers 2Synthetic biology offers new opportunities for interdisciplinary collaboration 2Supervolcano eruption -- in Sumatra -- deforested India 73,000 years ago 2Bausch 26 Lomb Vision Care Strengthens Its Commitment to ReNu 28R 29 Brand and the Eye Care Community 50159 1Bausch 26 Lomb Vision Care Strengthens Its Commitment to ReNu 28R 29 Brand and the Eye Care Community 50159 2Bausch 26 Lomb Vision Care Strengthens Its Commitment to ReNu 28R 29 Brand and the Eye Care Community 50159 3Positive CHMP Opinion for JAVLOR 28R 29 in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum Containing Regimen 50155 1Positive CHMP Opinion for JAVLOR 28R 29 in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum Containing Regimen 50155 2Positive CHMP Opinion for JAVLOR 28R 29 in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum Containing Regimen 50155 3RainEarth Obtains Patent Approvals for Its Core Technology 50153 1RainEarth Obtains Patent Approvals for Its Core Technology 50153 2RainEarth Obtains Patent Approvals for Its Core Technology 50153 3
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