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LCQ in Biological Technology

Determination of Acepromazine and its Major Metabolite in Equine Serum by LC-MS/MS using the Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

Chromatography and Mass Spectrometry Application Report Key Words Sensitivity Quantitation Finnigan LCQ Deca XP Plus Equine serum Acepromazine Gargi Choudhary, Thermo Electron Corporation, San Jose, CA USA Wayne Skinner and Scott Stanley, Universi...

Fully Automated Nano-Electrospray Coupled with a Finnigan LCQ Deca XP Plus for Sub-fmol Proteomic Analysis

Dirk Chelius, Terry Zhang, and Ken Miller; Thermo Electron Corporation, San Jose, CA Key Words Sensitivity Proteomics Finnigan LCQ Deca XP Plus PepFinder Kit Finnigan Surveyor HPLC LC/MS/MS Introduction Detection limits of mass spectro...

Sensitivity and Quantitation using a Finnigan LCQ Deca XP Plus Ion Trap Mass Spectrometer

Gargi Choudhary, Tania A. Sasaki, and Julian J. Phillips, Thermo Electron Corporation, San Jose, CA Chromatography and Mass Spectrometry Application Report Introduction Ion trap mass spectrometry is widely recognized for solving analytical problems requi...

Analyzing Trace-Level Impurities of a Pharmaceutical Intermediate Using an LCQ Deca Ion Trap Mass Spectrometer and the Mass Frontier Software Package

Mark R. Kagan 1 , Julian Phillips 2 , Carrie Liu 3 1Thermo Finnigan, Piscataway, NJ; 2Thermo Finnigan, San Jose, CA; 3Eisai Research Institute, Andover, MA Chemical Structure Validation ...

Complex Peptide Mixture Analysis on the Finnigan LTQ Linear Ion Trap Mass Spectrometer

... quadrupole ion trap systems, such as the Finnigan lcq Deca XP Plus and the Finnigan ProteomeX. Recent de... Mass Spectrometers Finnigan LTQ, and Finnigan lcq Deca XP Plus Ionization mode: NanoSpray...rent LC gradients on the Finnigan LTQ and Finnigan lcq Deca XP Plus. Figure 1 shows a four-fold increase ...

Use of On-line Size Exclusion Chromatography (SEC) for Sample Clean-up in LC/MS Analyses

...ughput screening to ADME/Tox studies. The Finnigan lcq series ion trap mass spectrometers meet the demand... Surveyor MS Pump and Autosampler and a Finnigan lcq Deca XP Plus mass spectrometer operated in both fu...p technology, have increased the ruggedness of the lcq Series mass spectrometers. They are capable of wit...

Detection and Identification of Phosphorylation Sites in Proteins Using LC/MS/MS with Neutral Fragment Loss Mapping

...can be acquired using any Thermo Finnigan lcq Series ion trap mass spectrometer. ...c flow splitter (Michrom) Thermo Finnigan lcq Deca XP mass spectrometer fitted with NanoSpray Io...automated coupling of the Surveyor LC and lcq Deca XP. The data acquisition process included a f...

Characterization of Protein Oligosaccharides Using MSn

...ted here can be acquired using the Thermo Finnigan lcq Series of ion trap mass spectrometers. ...other fragments. The MS n capabilities of the lcq Series present a powerful solution to these prob... and higher relative intensity. As a result, the lcq Series reveals structural details otherwise lost...

In-Vitro Metabolism Studies Using Data-Dependent LC/MSn

...ted here can be acquired using the Thermo Finnigan lcq Series of ion trap mass spectrometers. ...a candidate molecule. The Thermo Finnigan lcq Series, with their ability to perform multi-stage ...greater specificity. An additional strength of the lcq Series is their ability to perform automa...

Enhancing Ruggedness and Full-Scan MS Sensitivity Using Ion Sweep Technology

...e can be acquired using a Thermo Finnigan lcq Advantage, lcq Deca XP, and Deca XP Plus ion trap mass s... Ion Sweep technology that is now standard on both lcq Deca XP Plus and...
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