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LABA in Medical News

News briefs from the August issue of Chest

...ans. NEW REVIEW DEBATES NEED FOR ADDITIONAL laba SAFETY TRIALS In a new commentary, Malcolm R. Se...DA of safety outcomes of 60,954 individuals in 110 laba trials. Results of the analysis found that laba used with mandatory inhaled corticosteroid (ICS) w...

News briefs from the July issue of CHEST

...ic persistent asthma. However, in a metaanalysis of 32 studies (n=1,105 patients), researchers from McMaster University in Ontario, Canada, found that laba therapy had no effect on sputum, bronchoalveolar lavage (BAL), or mucosal inflammatory cell findings in adults or children. LABAs did decrease exhaled...

Perforomist(R) Inhalation Solution Data in Patients With Moderate to Severe COPD to Be Presented at the International Conference of the American Thoracic Society

...ts (LABAs). LABAs may increase the risk of asthma-related death. Data from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with ...

Dey, L.P. Highlights Perforomist(R) Inhalation Solution Data to Be Presented at the International Conference of the American Thoracic Society

...onists (LABAs). LABAs may increase the risk of asthma-related death. Data from a large placebo-controlled U.S. study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with ...

GlaxoSmithKline Statement on FDA Advisory Committee Vote on Use of Asthma Medicines Containing Long-Acting Beta-Agonists

...his recommendation is consistent with national treatment guidelines -- based on evidence and developed by experts -- that support the combination of a laba and ICS as a preferred treatment for children and adults with persistent asthma. We will continue to work with physicians to encourage broader underst...

Experts Highlight New Tool as a Timely Addition to Asthma Treatment

...y during the last decade. Recent concern raised by the FDA has the potential to affect the prescribing habits of physicians who may elect to utilize a laba with an ICS preparation. In view of the potential change in the landscape of therapy for bronchial asthma, measurement of the level of inflammation us...

Concomitant treatment with nebulized formoterol fumarate & tio-significant improvements -- COPD

...inergic) in 130 adults with moderate to severe COPD. These data provide additional insight into the additive benefit of concomitant therapy with a laba and a long-acting anticholinergic, said Dr. Donald Tashkin, MD, FACP, FCCP, Professor of Medicine, David Geffen School of Medicine at the University o...

Study analyzed SYMBICORT in children with persistent asthma

...ave their sleep affected by asthma symptoms,6 said Kathy Lampl, MD, Director, Clinical Research, AstraZeneca. Combination therapy with inhaled ICS and laba is one of the recommended regimens for children who have moderate to severe persistent asthma or are not controlled with ICS therapy alone, according ...

Clinical Trial Data for Perforomist(TM) Inhalation Solution to be Presented at ATS on May 20, 2008

...ta from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD tre...

News briefs: May issue of the journal Chest

...reduced severe exacerbations by 21%, and patients given LABAs did not differ in all-cause or respiratory-related mortality. The review also found that laba treatment was associated with significantly more severe COPD exacerbations compared with tiotropium. This study is published in the May issue of the j...
LABA in Medical Technology

GlaxoSmithKline and Theravance Announce Start of Large Phase 2B ICS and LABA Studies for Asthma in the Horizon Program

Compound 642444 and Compound 685698 advance in clinical development for the treatment of asthma LONDON, PHILADELPHIA and SAN FRANCISCO, Jan. 3 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: GSK ) and Theravance, Inc. (Nasdaq: THRX ) today announced the start of large...

Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma

... receive one of three Aerovant doses (1 mg, 3 mg or 10 mg) or placebo by inhalation twice daily for 12 weeks, during which time their standard ICS and laba therapies will be gradually withdrawn. The primary endpoint is exacerbation incidence on Aerovant therapy as compared to placebo. Secondary endpoint...

Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged Bronchodilation and Increased Patient Satisfaction Compared to Albuterol/Ipratropium MDI

...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this COPD treatme...ta from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in...

Results From One-Year Study Suggest Advair(R) Provides Important Benefits for African American Patients With Asthma

...irst prospective study to assess the addition of a laba to an ICS compared to ICS alone in African America...t treatment guidelines recommend the addition of a laba to an ICS in patients with moderate to severe asth... on an ICS alone. Taken in combination, an ICS and laba fight the two main components of asthma -- inflamm...

Study Analyzed SYMBICORT(R) in Children with Persistent Asthma

...their sleep affected by asthma symptoms,"(6) said Kathy Lampl, MD, Director, Clinical Research, AstraZeneca. "Combination therapy with inhaled ICS and laba is one of the recommended regimens for children who have moderate to severe persistent asthma or are not controlled with ICS therapy alone, according ...

Concomitant Treatment With Nebulized Formoterol Fumarate and Tiotropium Provides Clinically Significant Improvements for COPD Patients

... additional insight into the additive benefit of concomitant therapy with a laba and a long-acting anticholinergic," said Dr. Donald Tashkin, MD, FACP, FCCP...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD tre...

Concomitant Use of Nebulized Formoterol Fumarate and Tiotropium Provides Significant Improvement in Dyspnea, COPD Symptoms and Rescue Medication Use over Tiotropium Alone

...ta from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD tre...

Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD

...ta from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD tre...

Data from Three Clinical Trials for Perforomist(TM) Inhalation Solution to be Presented at CHEST 2007 on October 24, 2007

...ta from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in...stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD tre...

Clinical Trial Data for Perforomist Inhalation Solution to be Presented at ATS on May 20, 2007

...ed treatment option for the millions of COPD patients at earlier treatment stages who would benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, the clinical benefit of this new COPD treatment may be a valuable clinical option for patien...
LABA in Biological Technology

Nebulized Formoterol Fumarate Has Comparable Pharmacokinetic and Pharmacodynamic Profile to Dry Powder Formulation

...e widely used treatment option for many COPD patients at earlier treatment stages who could benefit from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For example, this new COPD treatment may be a valuable clinical option for many patients whose symptoms a...

PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday

...c agonists (LABAs). LABAs may increase the risk of asthma-related death. Data from a large placebo-controlled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with ...

Mylan Inc. Subsidiary, Dey, L.P., Announces that Perforomist(TM) (Formoterol Fumarate) Inhalation Solution is Now Available for Maintenance Treatment of COPD

...eatment guidelines recommend that physicians use a laba (such as Perforomist(TM) Inhalation Solution) as a...ontrolled US study comparing the safety of another laba (salmeterol) or placebo added to usual asthma ther...from twice-daily maintenance dosing of a nebulized laba such as Perforomist(TM) Inhalation Solution. For e...
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