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Knocks in Medical News

Burn Machine Speed Bag Knocks 'em Out at Shriners Wheelchair Bodybuilding Camp

REDFORD, Mich., Dec. 3 /PRNewswire/ -- Representatives from the fitness company Burn Machine ( www.TheBurnMachine.com ) paid a visit to the Shriners Hospitals for Children in Chicago last month to contribute to an extraordinary, albeit unique, cause; The Burn Machine donated more than $1500 worth ...

Combo Therapy Knocks Out Melanoma Tumors

Chemo was more effective after a protein in growths was inhibited, researchers say SUNDAY, June 1 (HealthDay News) -- Chemotherapy may be more effective on melanoma tumors if a protein frequently found in the growth can first be disabled, a new study reports. Researchers at the Duk...

New drug candidate knocks out resistant form of chronic myeloid leukemia

PORTLAND, Ore. Oregon Health & Science University Cancer Institute researchers have found a new, experimental drug candidate it to be effective against a highly resistant mutation in chronic myeloid leukemia (CML). This drug candidate could build on the legacy of Gleevec, which has been the ...

The Tech Savvy Patient Knocks on the Doors of Telemedicine and Virtual Clinics

Britain: Technology savvy patients are experimenting with medical consultations and patients are seen tapping the online medium// to seek solutions to many of their medial ailments, especially ones they would like to hide in the closet. Thrush, ringworm and urinary infections scored very high...

Pot, Cigarette Smoke Wreaks Havoc on Lungs

... most impressive finding is the synergism between tobacco and marijuana smoking." "A modest amount of pot smoking added to cigarette smoking really knocks your lungs for a loop," Edelman added. "One wonders if this is a chemical synergism or behavioral -- those who smoke both pot and tobacco inhale each ...

Researchers Report Progress in Fight Against Fat

...s for food. But, Ozcan said, it turned out that fat people -- and fat mice -- were immune to the hormone's effects. "Leptin comes to the brain and knocks on the door, but the brain doesn't hear it," he said. For the new study, Ozcan and his colleagues found that two existing, FDA-approved drugs coul...

Spinal Surgery and Determination Save Lioness

... SARASOTA, Fla., May 28 /PRNewswire/ -- Olla has had some hard knocks in her life, including those that shattered her canine teeth, a legacy from one of her owners. Then, in March, the 400-pound lioness lost the use of h...

Chemotherapy might help cancer vaccines work

...ctiveness of this promising type of cancer therapy, according to a study by researchers in the Duke Comprehensive Cancer Center. Chemotherapy first knocks out T regulatory cells that suppress immune function and we speculated that this might have a complementary effect when used in conjunction with vacci...

OHSU Cancer Institute researchers pinpoint how smoking causes cancer

...or, Grover Bagby, M.D., further stated that: Dr. Hays work shows that FANCD2 is an important protein in protecting against cancer, and cigarette smoke knocks out its production. Although there are probably other proteins involved in this process, we know this is a key one because cells with very high levels...

Liver cancer marker could yield blood test for early detection

... altered by environmental circumstances and is not inherited. Since the cells protein making system cant access the gene, hypermethylation effectively knocks out the tumor-suppressing RASSF1A gene, which is then unable to stop cells from becoming cancerous. While hypermethylated RASSF1A would make a use...
Knocks in Biological News

New drug agent knocks out multiple enzymes in cancer pathway

A team of 24 researchers from the U.S., Europe, Taiwan and Japan and led by University of Illinois scientists has engineered a new anti-cancer agent that is about 200 times more active in killing tumor cells than similar drugs used in recent clinical trials. The study appears this week in the ...

UCSF researchers identify new drug target for Kaposi's sarcoma

... well as other members of this viral family. "All known herpes virus proteases are structurally similar," Craik explained. "The inhibitor we found knocks out not only KS, but also the cytomegalovirus protease, so the site we've identified here could be a target for a broad-acting inhibitor against the e...

A natural approach for HIV vaccine

...ity have laid out a new approach. They have identified a diverse team of antibodies in "slow-progressing" HIV patients whose coordinated pack hunting knocks down the virus just as well as their super-antibody cousins fighting solo. By showcasing the dynamic, natural immune response in these exceptional...

Researchers identify 4 genetic hotspots associated with psoriasis

...of polymorphisms (mutations) in the IL-12/23 pathways. Third, we now find a third polymorphism in this same cluster, IL-23A. Fourth, a treatment that knocks down IL-12 and IL-23 recently has been shown to be a very effective treatment for psoriasis." This, plus the clustering of polymorphisms the IL-1...

Rare cancer-causing syndrome found, for the first time, in Singapore

...th LFS are at increased risk for developing multiple primary tumors of many different origins. In cancer patients who do not have LFS, cancer normally knocks out the normal function of p53 in order to grow and metastasize. But when a person only has one working copy of the gene to begin with, the chance tha...

From a lowly yeast, researchers divine a clue to human disease

...es strung along a single length of DNA are separated by gaps to mark boundaries. As the polymerase reaches the end of a gene, Sen1 flips a switch and knocks it off the DNA track. The group, led by Brow and Eric Steinmetz, compared normal yeast to a strain with a mutated form of Sen1 that does not see t...

New light microscope sharpens scientists' focus

...esion proteins, mitochondria, and the Golgi apparatus. "Performance-wise, it's just astounding. And simplicity-wise it's astounding," Betzig said. "It knocks the socks off of standard fluorescence microscopy from a resolution perspective." Hess added, "This level of detail was previously only obtainabl...

ANU scientists crack DNA replication mystery

...f how TUS stops the replisome in this directional manner. "When the replisome comes along from one direction, separation of the two DNA strands simply knocks the TUS off as you'd expect. But when it comes from the other direction, the strand separation near TUS leads to one of the DNA bases flipping over an...

Mice lacking social memory molecule take bullying in stride

...eered to lack this memory molecule continued to welcome strangers in spite of repeated social defeat. Their unaltered peers subjected to the same hard knocks became confirmed loners ?unless the researchers treated them with antidepressants. "For both mice and men, social status is important; for mice, l...

Master genetic switch found for chronic pain

... experiments with mice, researchers have found that eliminating what appears to be a master genetic switch for the development of pain-sensing neurons knocks out the animals' response to "neuropathic pain." Such pain is abnormal pain that outlasts the injury and is associated with nerve and/or central nervo...
Knocks in Biological Technology

MIT, BU team combats antibiotic resistance with engineered viruses

...developing antibiotic resistance and help kill those that have already become resistant. Researchers from both schools have engineered a virus that knocks out bacterial defense systems, enhancing the effectiveness of antibiotics. The work is reported in the March 2 online issue of the Proceedings of the...

Wisconsin Manufacturing and the Machinery for Change

...onsin got a much-needed boost from a recent Barrons Magazine story entitled Rust Removal. The Milwaukee Journal Sentinel published, Barrons article knocks the rust of state manufacturing outlook , in which I discussed some of the economic reasons for a Wisconsin and Midwestern manufacturing recovery, inc...

Hey Willie, Wisconsin Manufacturing Doesnt Need an Aid Concert!

...ew round of Wisconsin economic growth. Six months ago I wrote an article which the Milwaukee Journal Sentinel published, entitled Barrons Article knocks the Rust Off State Manufacturing Outlook, that recounted the predictions of a hedge-fund manager named Jeff Gendell in an interview from a December ed...

UW-M engineering dean heads for promising medical business

... a certain tissue. Today coming up with a solution to one of his experiments and estimating those properties takes him about 15 minutes; his technique knocks that down to 1 second. "That's one of the reason I'm excited about this," Chris said. The other reason is that NovaScan's research has the potentia...

Brand Bullies- Entrepreneurs draw legal action over common words

...e to this litigation, we were forced to give up use of the word, and to rename our company, and still be in litigation with them," Smith says. "So, it knocks you off your rhythm, and that's their whole goal." For Part II of this story, see Beware -- Use of the word 'entrepreneur' can put you in a legal...

Embracing failure is a necessary step for successful entrepreneurs

...ailures for what those mistakes taught them and used the experience to move to the next idea. Embracing failure as a teacher in the school of hard knocks was the theme of last weeks Ideas to Profits conference at UW-Whitewater, where the Wisconsin Innovation Service Center marked its 25th year of helpin...

9 tips for making 90 seconds count in an investment pitch

...evator Pitch Olympics, a yearly event at the Wisconsin Early-Stage Symposium . This year, a panel of eight investors dished out advice and a few hard knocks to hopeful entrepreneurs who presented their businesses in front of an audience. Most people speak at between 100 and 200 words per minute. Think a...

Early-stage quality brings investment, Meier says

...le now starting their second and third companies, Meier noted. They either have gone through programs here in the state, or through the school of hard knocks they have learned what's necessary to actually get a company on that high-growth path. Life science bias Teresa Esser, managing director of S...
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