Dealing deadly cancers a knockout punch
New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers. Reovirus, a non-pathogenic virus under development at Calgary, Alberta-based Oncolytics Biotech, has shown powerful anti-cancer activity against cultured tumor cells, in animal models, and in human clinical trials. Oncolytics' proprietary reoviru...TargeTron Gene Knockout System from Sigma-Aldrich
Description:The TargeTron(TM) Gene Knockout System provides optimized reagents and protocols for the rapid and specific disruption of bacterial genes by insertion of group II introns. The method exploits the retrohoming ability of group II introns and utilizes a simple PCR step to re-target the TargeTron group II intron for specific insertion into the host genome. Utility of the technology has been demonstra...Chilean President's Cousin Successfully Tests Allergy 'Knockout' Technique on Mice
A doctoral student at the Hebrew University of Jerusalem School of Pharmacy, who is the first cousin of Chilean President Michelle Bachelet, has been conferred a prestigious research prize for developing a new approach that may help eliminate allergies like the common cold and asthma. Chilean-born Ido Bachelet has been honoured with the Barenholz Prize, which is named for the dono...