Sex Ends as Seasons Shift and Kisspeptin Levels Plummet
A hormone implicated in the onset of human puberty also appears to control reproductive activity in seasonally breeding rodents, report Indiana University Bloomington and// University of California at Berkeley scientists in the issue of Endocrinology. The paper is now accessible online via the jour...
Hormone Might Help Restore Female Fertility
spurs healthy ovulation, researchers explain
...DAY, March 17 (HealthDay News) -- A hormone called kisspeptin
may offer a new treatment for infertility, accordi... researchers injected the participants with either kisspeptin
or saline and then measured levels of two sex horm...
Predicting the future in ovarian cancer
and its receptor GPR54 predict a favourable clinic...umours. In this study, researchers have shown that kisspeptin
and GPR54 are independent prognostic biomarkers sp...They analysed the samples using antibodies against kisspeptin
and the G-protein-coupled receptor GPR54. Cases th...
Puberty may be due to GPR54 gene and KiSS-1 Molecule
...claim that the meeting of a gene and a molecule appear to trigger off puberty. "We now have very good evidence that the GPR54 gene and its switch, the kisspeptin
protein molecule produced by KiSS-1, are key to the initiation of puberty, when GnRH (Gonadotropin-Releasing Hormone) is released," Said Tony Plant, a...
News tips from the Journal of Neuroscience
...pment of sexually dimorphic traits. Gonadotropin-releasing hormone (GnRH) neurons were activated and released leutinizing hormone after treatment with kisspeptin
in wild-type male mice but not in micelacking GPR54 . GPR54- deficient males showed the expected male sexual behavior after treatment with testoste...
A gene's first 'kiss' sets off that affair known as puberty
...d evidence that the GPR54 gene and its switch, the kisspeptin
protein molecule produced by KiSS-1, are key to th... the researchers also found that by giving animals kisspeptin
they could, essentially wake up the reproductive h... their childhood hibernation. Within 30 minutes of kisspeptin
being administered to male monkeys, LH, one of the...