Navigation Links
Kinesin in Medical News

Motor proteins may be vehicles for drug delivery

...ins to the rest of the molecule is longer in kinesin-2 motors than in other kinesin proteins, which prevents efficient mechanical coordination between the two ...hereby slow the growth of tumors." The researchers also believe that the kinesin transport system could in the future be engineered onto microchips. "Our...

NYP/Columbia physician-scientists present at ASCO 44th annual meeting

...risk AML or following reduced-intensity AlloSCT in standard-risk AML. kinesin Spindle Protein (KSP) for Hodgkin's Lymphoma Dr. Owen O'Connor Director ...y College of Physicians and Surgeons A Phase 1 dose-escalation trial of kinesin Spindle Protein (KSP), a drug that targets a unique aspect of cancer cell d...

Research shines spotlight on a key player in the dance of chromosomes

...It turns out its like a little person it walks with its two feet, one in front of the other. I was interested to know whether the normal rules of how kinesin walks apply to these different kinds of kinesins. In vivo studies are hampered by the presence of lots of other proteins, making it hard to study h...

Tug of war in the cells

...e always involved in the tug-of-war over a cargo - for example, some of the kinesin type and some of the dynein type. The kinesin motors move to the end of the microtubule that biologists call the positive...

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

...portant role in Alzheimers disease. Dynein and kinesin proteins transport cellular cargo towards opposite...oes awry. The transport performed by dynein and kinesin is required for continuously providing new protein...ules are abundantly decorated with tau. Dynein and kinesin encounter the tau molecules on their travels along...

Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells

... family of "motor proteins," called kinesins. Each kinesin facilitates the transport of specific surface mark...nderstanding of processes directed by the specific kinesin family members marks a big step forward in develop... its environment," Dr. Kreitzer explains. These kinesin "trains" work by moving their cargoes along filame...

Experimental cancer pharmaceuticals under trial

... A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell...apy, they say. The experimental drug, GSK923295A, inhibits the mitotic kinesin centromere-associated protein E (CENP-E), which is required during mitosis,...
Kinesin in Medical Technology

Cytokinetics Announces Non-clinical Data to be Presented at the 2007 AACR Annual Meeting

...nt data evaluating ispinesib, a novel inhibitor of kinesin Spindle Protein (KSP), in models of multiple myelo...l Meeting Ispinesib: Abstract #1435: kinesin Spindle Protein Inhibition for the Treatment of ...rative research activities directed to the mitotic kinesin centromere-associated protein E (CENP-E). GSK-9232...

Cytokinetics Reports Additional Clinical Trials Data for Ispinesib

...ibitor of kinesin spindle protein (KSP), a mitotic kinesin essential for proper cell division. Ispinesib has...rial are expected in 2007. Background on Mitotic kinesin Inhibitors Since their introduction over 40 year...ispinesib and SB-743921, each a novel inhibitor of kinesin spindle protein (KSP), a mitotic kinesin. Ispines...
Kinesin in Biological News

Dartmouth researchers find new protein function

...his study on NOD provided evidence for a new way a kinesin motor could function," said Jared Cochran, a postd...ir paper is titled, "ATPase Cycle of the Nonmotile kinesin NOD Allows Microtubule End Tracking and Drives Chr...nt." "Before this study, it had been shown that kinesin motors either walked along their microtubule track...

Media highlights in the January issues of Biophysical Journal

...ing their phosphorylation status. Likewise numerous biophysical studies have explored the mechanics of single motor proteins of the myosin, dynein and kinesin families involved. Here, a biomechanical approach is taken, where in living cells the tension of the cytoskeletal network is monitored by atomic f...

Biophysical Society announces winners of 2008 Student Travel Awards

...Known to Cause Familial Hypertrophic Cardiomyopathy. Nicholas R. Guydosh, Stanford University, Direct Observation of Individual Head Motions in kinesin Dimers. Sejin Han, University of Maryland, College Park, Abnormal Formation and Remodeling of Fibers Containing Type I Collagen Homotrimers. ...

Researchers image molecular motor structural changes

...s. For the study, Endow and her colleagues chose a kinesin found in baker's yeast that closely resembles kine...resolution models and combined them with models of kinesin and microtubule structures rendered using another ... defects in kinesins. Finding methods to stimulate kinesin activity might help in the treatment of these huma...

Biological motors sort molecules one by one on a chip

... 15 micrometers in length) were then transported over the 'carpet' of motors. The microtubules are, as it were, 'crowd surfing' over the sea of small kinesin motors. A particular challenge of the research was to ensure beforehand that the microtubule tubes could be transported in a determined direction and ...

A new way of looking at molecular motors

...dness and kidney disease to neurodegenerative disorders and parasitic diseases such as malaria. All complex organisms use myosin and its relatives, kinesin and dynein, to move substances around inside cells and to help cells move from one place to the other. Myosins also help parasites enter and infect ho...

Marathon of nano-sprinters

...ded by the hydrolysis of ATP, which can be considered the fuel of the cell. kinesin and dynein motors move along microtubules and myosins move along actin fila... function of the maximum number of motors that can pull this par-ticle. For kinesin motors, for example, calculations show that only seven or eight motors are ...

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...discovered that two molecular motors -- dynein and kinesin -- do not compete for control, even though they wa...l motors measured outside the cell." Dynein and kinesin are biomolecular motors that haul cargo from one p...es material from the cell membrane to the nucleus; kinesin moves material from the cell nucleus to the cell m...
Kinesin in Biological Definition

Dynein

...ing within flagellar microtubules , whereas the cytoplasmic dynein is implicated in moving toward the negative end of a microtubule. See also: kinesin External links How Cilia and Flagella Work (axonemal dynein) Microtubule Based Movement (cytoplasmic dynein) ...

List of gene families

...g immune system proteins Major histocompatibility complex (MHC) Related protein families Motor proteins Myosin kinesin Dynein Signal transducing proteins Receptor tyrosine kinases G-proteins Transporters ABC proteins ...
Kinesin in Biological Dictionary

Transport protein

... protein . From Wikipedia, the free encyclopedia. Jump to: navigation, search ... Categories: Disambiguation pages | Transport proteins ... kinesin accomplishes transport by essentially "walking" along a ... Biology Proteins Vesicles Carrier Protein Transport Cytoskeleton M...

Dynein

...orkshop 2009 have been announced! ... Cytoplasmic dynein is a protein complex responsible for the transport of a large ... Dynein , along with kinesin (see previous ALS highlight, "Kinesin Action ... AAA+ Ring and Linker Swing Mechanism in the Dynein Motor ... Single-Molecule Analysis of Dynein...

Cell biology

...copy. Interactive... Cell Models. Mitosis ... Funding opportunities for students & fellows. Postdoc Job Opportunities. Confocal Reservations. kinesin Home. 2009 Stem Cell Symposium Registration ... Cell structures and functions. A visual tour inside the cell that highlights each organelle. ...
Other Tags
(Date:7/11/2014)... Ticket Down is a reliable source for ... When it comes to the summer concert schedule, it just isn’t ... is one of the biggest names in country music and one ... out on his “That’s My Kind of Night” tour featuring Lee ... be making through the rest of the summer and into the ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 According to ... & Application Market by Communication Technology (ZigBee, Z-Wave, Bluetooth, ... Electronics, Industrial, Automotive & Transportation, Agriculture) & Geography - ... value of Internet of Things market was worth $1029.5 ... Billion by 2020, at an estimated CAGR of 4.08% ...
(Date:7/11/2014)... Presently, disposable medical suppliers call for the biggest ... During the past two decades, the world market for ... 12.5% per year), primarily owing to the importance of ... the largest market for disposable medical supplies in the ... position is held by Europe with a 29% market ...
(Date:7/11/2014)... 2014) Obese and overweight firefighters are not ... providers, according to new research from The University ... , National guidelines state that health care professionals ... maintaining a healthy weight. Firefighters have high rates ... cause of line-of-duty deaths in firefighters. This study ...
(Date:7/11/2014)... to repair damage to the anterior cruciate ligament (ACL) -- ... could increase a young athlete,s risk for further injuries, researchers ... aged 8 to 16, who had ACL reconstruction surgery. Of ... their injury, 37 had surgery six to 12 weeks after, ... their injury. The youngsters who had surgery later had ...
Breaking Medicine News(10 mins):Health News:Luke Bryan Ticket Prices Slashed at Concord Pavilion 2Health News:Luke Bryan Ticket Prices Slashed at Concord Pavilion 3Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 2Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 3Health News:Delaying Kid's Knee Surgery Could Be a Bad Play, Study Finds 2
(Date:7/11/2014)... July 11, 2014 Research and Markets ... Biometrics Technology Market - Industry Analysis Size Share Growth ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... has created a need for high level security in ... personnel authentication such as username and passwords, tokens etc. ...
(Date:7/11/2014)... de Janeiro, Brazil- In the brains of all ... that allows an electric or chemical signal to ... Chemical synapses, which are the most abundant type ... Synapse formation is crucial for learning, memory, perception ... inhibitory synapses critical for brain function. For ...
(Date:7/10/2014)... 27, 2014  The American Academy of Forensic ... Standards and Technology (NIST) and the Department of ... and forensic science expert members to the Forensic ... element of the NIST,s Organization of Scientific Area ... first appointments made to the new FSSB that ...
Breaking Biology News(10 mins):International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2Blame it on the astrocytes 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
Other Contents