Elusive HIV shape change revealed; Key clue to how virus infects cells
Structural biologists at Children's Hospital Boston and Harvard Medical School have shown how a key part of the human immunodeficiency virus (HIV) changes shape, triggering other changes that allow the AIDS virus to enter and infect cells. Their findings, published in the Feb. 24 issue of the journal Nature, offer clues that will help guide vaccine and treatment approaches. Researchers led...Key molecule in plant photo-protection identified
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Researchers Uncover Key Step In Manufacture of Memory Protein
A cellular enzyme appears to play a crucial role in the manufacture of a protein needed for long-term memory, according to a team of researchers led by scientists at the National Institute of Child Health and Human Development of the National Institutes of Health. The protein is known as mBDNF, which stands for mature brain-derived neurotrophic factor. In an earlier study, another team of...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
The replenishment of missing neurons in thebrain as a treatment for Parkinson disease reached the stage of humantrials over 15 years ago, however the field is still in its infancy.Researchers from Kyoto University have now shown thatdopamine-producing neurons (DA neurons) generated from monkey embryonicstem cells and transplanted into areas of the brain where these neuronshave degenerated i...In the sea slug's defense against lobsters, confusion is key
Like many other marine creatures, Aplysia, a common sea slug, enlists chemical defenses against its predators, but the mechanisms by which such chemical attacks actually work against their intended targets are not well understood by researchers. New work has now shown that such chemical defenses can involve modes of trickery that had not previously been appreciated as components of chemical defen...Rhesus Monkey IFN Alpha from PBL InterferonSource
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Stratagene Cloning Systems Eagle Eyes Still Video System shown with Darkroom Cabinet Stratagenes new Eagle Sight software version 3.0 allows researchers to determine integr...DHC 2007: Controlling health IT costs the key to capturing value
Why that distortion exists could be the subject of an entire conference, and it occupied a fair amount of time during Digital Healthc...Regional collaboration is key to state's future
Our state boasts significant competitive advantages in terms of talent, technology, and capital, but alone we lack the critical mass needed to compete with our most significant competition - the East and West C...Lean Protein Could Be Key to Obesity Drugs
A protein that lets mice eat more but weigh less could prove the magic ingredient for diet drugs of the future.British scientists from drug giant SmithKline Beecham and the University of Cambridge have created mice with a human protein known as Uncoupling Protein 3 (UCP3) that increases their metabolism.In what is every dieter's dream, the mice were able to eat more than normal mice but s...Birth weight key factor in heart diseases
Sluggish growth in the first year of a boy's life greatly increases the risk of heart diseases as an adult, according to a study of Finnish children. The key factor in heart disease is not how much you weigh now, but how you grew in the past. It's long been known that babies with a low birth weight are roughly twice as susceptible to coronary heart disease in adulthood as heavier babi...Farm boy's death raises human bird flu fears in Turkey
A 14-year-old Turkish boy who worked on a poultry farm and was one of six people tested for bird flu died on Sunday, and his sister was in a critical // and worsening condition, doctors said. Doctors are still waiting for test results and could not immediately confirm whether the fatality was caused by bird flu. If confirmed, it would be the first human fatality in Turkey from the viru...Obese women likey for Cesarean
Fat women are more likely for Cesarean delivery, says Dr.Bell from Duke University NC. Years ago, anesthesia had been one of the major causes of maternal mortality.// Pregnancy and obesity both make it difficult to breathe under general anesthesia, so a woman's risk is doubled when the two conditions are combined. Bell and colleagues studied more than 3000 women and calculated e...Solstice Neurosciences Presents Escalating Dose Study at International Congress in Istanbul, Turkey
MALVERN, Pa., June 15, 2007 /PRNewswire/ -- SolsticeNeurosciences, Inc. today reported important results from amulticenter, forced dose escalation study of Botulinum Toxin Type BInjectable Solution (Myobloc(R)) recently presented at the 11thInternational Congress of The Movement Disorders Society inIstanbul, Turkey. This was the first multicenter study to confirm patient safetyand...Prana Biotechnology Presents New Key Findings on PBT2
PBT2 Alters Biomarkers and Rapidly Improves Cognition in twodistinct models of Alzheimer's Disease MELBOURNE, Australia - June 7, 2007 - Prana BiotechnologyLimited (NASDAQ: PRAN / ASX: PBT), a biopharmaceutical companyfocused on the research and development of treatments forneurodegenerative disorders, announced today that it will presentnew data on Prana's lead Alzheimer's disease (AD) d...BDSI Announces Positive Key Secondary Efficacy Endpoint Results for Bema Fentanyl
MORRISVILLE, N.C.--(BUSINESS WIRE)--May 14, 2007 - BioDeliverySciences International, Inc. (Nasdaq: BDSI) announced additionalstatistically significant results with BEMA Fentanyl in cancerpatients with breakthrough pain in its Phase III efficacy clinicaltrial for the product. Results were based on the company's continuing analysis of thesecondary efficacy endpoints from the study. A key s...Schepens Scientists Identify Key to Integrating Transplanted Nerve Cells Into Injured Tissue
Discovery promises to make retina, spinal cord and other centralnervous system transplants possible BOSTON, April 26, 2007 /PRNewswire/ -- Scientists at theSchepens Eye Research Institute, an affiliate of Harvard MedicalSchool, have identified a key mechanism for successfullytransplanting tissue into the adult central nervous system. Thestudy found that a molecule known as MMP-2 (which is...