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Keratinocyte in Medical News

Derma Sciences Enrolls First Patient in DSC127 Phase II Study

...could have blockbuster potential." DSC127, a topically applied pharmaceutical, has been shown to promote healing in a variety of ways; by increasing keratinocyte proliferation, extracellular matrix production, and vascularization. Peer reviewed articles on the technology as applied to wound healing and scar r...

Protein 'switch' suppresses skin cancer development

...'s group found evidence that IKKα functions as a sentry that monitors keratinocyte proliferation and then induces terminal differentiation. In one experiment,...p that activates EGFR and other growth factors previously found to regulate keratinocyte proliferation and differentiation. Another experiment demonstrated that...

Cellular decision on the computer

...d is relevant not only for basic medical research, but also forges new paths in cancer medicine. H. Busch et al. Gene network dynamics controlling keratinocyte migration. DOI:10.1038/msb.2008.36 The task of the Deutsches Krebsforschungszentrum in Heidelberg (German Cancer Research Center, DKFZ) is to system...
Keratinocyte in Medical Technology

Derma Sciences to Enter Phase II Development of Wound Healing Product That May Use Body's Own Naturally Occurring Stem Cells

...t the rapid healing of tissue. Application of DSC127 in various animal models has resulted in the increased pace of angiogenesis, as well as increased keratinocyte and extracellular matrix production, all key drivers for dermal repair. U.S. Biotest, founded by Drs. Gere diZerega and Kathleen Rodgers, maintains ...

Dr. Gabriel Sosne to Present New TB4 Data at 2007 ARVO Meeting

...nt in virtually all human cells. It is a first-in-class drug candidate that promotes endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition, and down-regulates inflammation. One of TB4's key mechanisms of action is its ability to regulate the cell-building pr...
Keratinocyte in Biological News

Tips from the American Journal of Pathology

...al testing of new therapeutics." Wolfram JA, Diaconu D, Hatala DA, Rastegar J, Knutsen DA, Lowther A, Askew D, Gilliam AC, McCormick TS, Ward NL: keratinocyte but not endothelial cell specific over-expression of Tie-2 leads to the development of psoriasis. Am J Pathol 2009, 174: 1443-1458 New Mark...

Time (and PPAR-beta/delta) heals all wounds

...blasts and therefore reduce the growth factor signals sent back to the keratinocytes. But in PPARβ/δ's absence, fibroblasts keep stimulating keratinocyte division. Similarly, PPARβ/δ knockout mice expressed less sIL-1ra after wounding and produced more growth factors that stimulate the epiderm...

Salk researchers successfully reprogram keratinocytes attached to a single hair

...luding heart muscle cells and dopamine-producing neurons, which are affected by Parkinson's disease. Taking advantage of the high efficiency of the keratinocyte reprogramming process, Aasen decided to test whether he could establish KiPS cells from minute amounts of biological samples. "We plucked a single hai...

Story ideas from the Journal of Lipid Research

...of skin cells, the scientists concluded. Article: Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation , by Yoo Bin Kwon, Chang Deok Kim, Jong-Kyung Youm, Hyung Sub Gwak, Byeong Deog Park, Seung Hun Lee, Saewha Jeon, Bo Joong Kim, Young-...

Molecular thermometers on skin cells detect heat and camphor

... that they have severe deficiencies in their ability to detect warm and hot temperatures. Patapoutian and his colleagues also showed that, in cultured keratinocyte cells, TRPV3 is activated by the compound camphor, which is one of the main ingredients in many warming rubs. TRPV3 is the first known receptor for ca...
Keratinocyte in Biological Technology

Histogen Aesthetics Launches ReGenica Rejuvenation System

...maintain an embryonic-like environment, including low oxygen and low gravity conditions. During this process, the cells secrete growth factors such as keratinocyte Growth Factor and Vascular Endothelial Growth Factor, and soluble extracellular matrix proteins such as collagens, laminin and decorin, which are asso...

Stratatech and Virent Win $4M in U.S. Grants

...as in automobiles." Stratatech: Artificial Skin Dr. Lynn Allen-Hoffmann, who discovered and developed the NIKS technology (Normal Immortalized keratinocyte that produce skin), founded the company in 1999 as a spinout of the University of Wisconsin-Madison to develop a range of living skin tissue products ...

Proteomics in Bladder Cancer Research: Protein Profiling of Bladder Squamous Cell Carcinomas, Rev C

... Characterization of SCC Proteins Utilizing the keratinocyte 2-D PAGE Database To date, ...tric focusing) 2-D PAGE image of noncultured human keratinocyte proteins as depicted on the Web (http:/..., 9397 (1990) Celis JE et al., The human keratinocyte two-dimensional gel protein database (u...
Keratinocyte in Biological Products

Vaginal Keratinocyte Progenitors, Rabbit from CHEMICON

Description: Kit containing Vaginal Keratinocyte Progenitors, Rabbit, and media. Cryo-preserved cells in medium containing 20% FBS and 10% DMSO at passage 25 (approx), supplied with kit (500 mL) of optimized medium.This cell culture is supplied as a long-term culture, and is guaranteed to provide an additional ...
Company:CHEMICON
Keratinocyte in Biological Dictionary

Fibroblast

...%, buy or rent. New and used books like Cell Surface Heparan Sulfate Proteoglycans As Co Receptors for Fibroblast ... Fibroblast Cell Solutions. keratinocyte Cell Solutions ... Cultures and Products "Tissue Biology "Primary Cells " Fibroblast Cell Solutions. How to Order ... What is fibroblast ? Meanin...
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