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KDR in Medical Technology

Entremed Presents Results of ENMD-2076 Phase 1 Study in Advanced Cancer Patients

...ncluding melanoma, renal cell, ovarian and colorectal cancer. ENMD-2076 was well-tolerated when administered daily. In addition, plasma soluble kdr (VEGFR2), a marker of effect against the VEGF receptor, was reduced in all patients when compared to baseline. Side effects included hypertension and...

EntreMed's Aurora Kinase Inhibitor Induces Tumor Regression in Preclinical Models

...athology of hematological cancers. Additionally, ENMD-981693 demonstrated potent inhibition of a spectrum of targets linked to angiogenesis, including kdr (VEGFR2) and FGFR1. The compound was also shown to induce apoptosis and cell cycle arrest in a broad range of cell lines. ENMD-981693 exhibited a...
KDR in Biological Technology

Large-scale genetic study sheds new light on lung cancer

...ptors (NTRK1 and NTRK3) and other receptor-coupled tyrosine kinases (ERBB4, kdr and FGFR4). These genes code for cell receptors coupled to members of the t... lung adenocarcinoma patients whose tumors have mutations that activate the kdr gene. In their Nature paper, TSP researchers also analyzed the patterns...
KDR in Biological Products

Anti-Human VEGFR-2 / KDR Antibody, Unconjugated from Cell Sciences

Description: Anti-human VEGFR-2/KDR (Protein-A Purified) Polyclonal Antibody...
Company:Cell Sciences
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