St. Jude projects 90 percent cure rate for ALL
The cure rate for the once almost universally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital. Almost 4,000 cases of ALL are diagnosed in the United States each year, about two-thirds of which are in...St. Jude test of bird flu vaccine proves successful
A commercially developed vaccine has successfully protected mice and ferrets against a highly lethal avian influenza virus, according to the investigator who led the study at St. Jude Children's Research Hospital. The vaccine was developed by Vical Incorporated in San Diego, California. This finding, coupled with results of previous studies that showed protection against multiple human inf...St. Jude finds clues to hearing loss from chemotherapy
Children with cancer who suffer hearing loss due to the toxic effects of chemotherapy might one day be able to get their hearing back through pharmacological and gene therapy, thanks to work done with mouse models at St. Jude Children's Research Hospital. Mice with a variety of genetic mutations that disrupt different parts of the ear will also help scientists understand age-related hearing loss...St. Jude announces breakthrough in eye cancer treatment
Scientists at St. Jude Children's Research Hospital have demonstrated in a mouse model a new, locally applied treatment for the eye cancer retinoblastoma that not only greatly reduces the size of the tumor, but does so without causing the side effects common with standard chemotherapy. The treatment also appears to be suitable for certain forms of breast, lung, prostate and colon cancer, and is s...St. Jude study shows genes play an unexpected role in their own activation
The “on switch,” a protein called CREB, is a transcription factor—a molecule that binds to a section of DNA near a gene and triggers that gene to make t...GE, St. Jude to collaborate on visualization technology
Under terms of the agreement, the health organizations will develop a system with fully integrated intracardiac echocard...Inexpensive ALL Follow-Up Test Developed By St. Jude Researchers
A simple and an affordable follow-up test to identify children with acute lymphoblastic anemia (ALL), who respond well to their first chemotherapy regimen, // has been developed by researchers at St. Jude Children's Research Hospital. Such children who have a good response may then be treated by a less aggressive treatment, during subsequent follow up visits. This new test is based on...