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Isoenzyme in Medical News

Gleevec(R) substantially reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors (GIST), The Lancet reports

...s become pregnant while taking Gleevec, the patient should be advised of the potential hazard to the fetus. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6 and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitor...

Prescription Copay Assistance for Patients taking Gleevec or Tasigna for Philadelphia chromosome-positive Chronic Myelogenous Leukemia (Ph+ CML)

...ntial toxicities--specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...

Photo: New Data Show Gleevec(R) Halts Progression to Advanced Stages of Life-Threatening Form of Leukemia in Sixth Year of Treatment

...otential toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...

Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies

...potential toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...

Fluorescent markers to distinguish Trypanosoma brucei strains causing Sleeping Sickness

... in this study broaden the spectrum of tools available for experimental studies on multiple-genotype infections. They are fundamentally different from isoenzyme analysis and other genotyping approaches in that they allow the distinction of parasite genotypes based on an easily recognizable phenotypic trait. ...
Isoenzyme in Medical Technology

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...ntial toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

...l toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...l toxicities--specifically liver, kidney and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6 and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitor...

Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease

...otential toxicities--specifically liver, kidney and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6 and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitor...

Positive Results Prompt US National Cancer Institute to Make Gleevec Available To Patients in Post-Surgical Gist Study

...th severe hepatic impairment should be treated at a starting dose of 300 mg/day and should be closely monitored Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...
Isoenzyme in Biological Technology

Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents

...t as a substrate of these same isoenzymes. The results of this in vitro metabolism study indicated that AHCC is not an inhibitor of the major CYP450 isoenzyme pathways. Therefore, AHCC is safe and unlikely to result in increased toxicity when used in combination with commonly used chemotherapeutic agents suc...

Gleevec Receives FDA Priority Review as First Therapy to Reduce Recurrence of Gastrointestinal Stromal Tumors After Surgery

...potential toxicities-specifically liver, kidney and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6 and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitor...

Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia

...otential toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use. Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monito...
Isoenzyme in Biological Products

Chicken Anti-Human Adenylate kinase isoenzyme 6 Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: Adenylate kinase isoenzyme 6...
Company:GenWay Biotech, Inc.

Mouse Anti-Human PDK2 Monoclonal Antibody, Unconjugated, Clone 2G1 from Novus Biologicals

Description:... Mouse monoclonal antibody to PDK2 - pyruvate dehydrogenase kinase, isoenzyme 2...
Company:Novus Biologicals
Isoenzyme in Biological Dictionary

Isoenzyme

Isozyme. From Wikipedia, the free encyclopedia (Redirected from Isoenzyme ) ... Isozymes (also known as isoenzymes) are enzymes that differ in amino acid ... Definition of isoenzyme from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and wor...
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