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Irradiated in Medical News

Experimental agents may prevent radiation-induced leukemia

...ts they prevent bone metastasis and because they have an ability to remove uranium from the body. For the current study, Miller and her colleagues irradiated laboratory mice at 3.5 Gy; all of the mice who were not treated with either EHBP or CAPBP developed leukemia. By contrast, if they were treated with...

Cat Food-Linked Illness Yields Clues to MS

...entists say. While looking into why pregnant cats on a special diet of irradiated food began to have problems with movement, including paralysis and vision, ...t was a "species specific" malady and that it was "extremely unlikely" that irradiated food posed a problem to humans. "The key thing is that it absolutely c...

Discovery may result in new test to determine predisposition to cancer

...iciently repair itself could result in cancer. In the study, researchers irradiated cells to create double strand breaks. They wanted to determine if a double ... instability all over the genome," Schiestl said. Specifically, the team irradiated cells and then transformed them with a DNA fragment that detects the effici...

Hollow gold nanospheres show promise for biomedical and other applications

...peptide to the nanospheres that enabled the particles to bind to tumor cells. After injecting the nanospheres into mice with melanoma, the researchers irradiated the animals' tumors with near-infrared light from a laser, heating the gold nanospheres and selectively killing the cancer cells to which the particle...

What is the mechanism of the chronic radiation enteritis?

...e IFNgamma /STAT1 pathway. At the same time-point, the immunosuppressive IL-10/STAT3 pathway, known to regulate the Th1/Th2 balance, was expressed, in irradiated rats, at approximately half its level as compared to controls. This suppression was associated with an overexpression of SOCS3, which inhibits the fee...

Dormant stem cells for emergencies

...dormant cell population awakes. Once awakened, it shows the highest potential for self-renewal ever to be observed in stem cells. If transplanted into irradiated mice, these cells replace the destroyed bone marrow and restore the whole hematopoietic system. It is possible to isolate new dormant stem cells from ...

Cancer research highlights

...modulated electron therapy (MERT). That's because the radiation dose of an electron beam falls off rapidly with distance, which allows the tumor to be irradiated at doses sufficient to kill cancerous cells, but spares the healthy tissue beneath from exposure to too much radiation. Murat Surucu ( msurucu@rad...

Math could help cure leukemia

...g. The authors suggest that such a stimulation can be provided in the form of "cancer vaccines," in which pre-therapy blood taken from patients is irradiated to kill active cancer cells, then introduced back to the patient. A strong stimulation of the immune system was shown to be active in vitro in Lee's l...

Sounding out Congo Red

... ultrasound, has so far been investigated only rarely as an alternative remediation technology. Under well-established 'extreme' conditions, materials irradiated with sound at frequencies around 50 kHz are essentially ripped apart by the formation of free radicals, say the researchers. Carbon dioxide and water ...

Irradiation Almost Erases Risk of Food Poisoning

...ripening of fruits or the sprouting of vegetables. irradiated foods, except for spices, must be labeled as such,...ain unchanged. "All the researchers showed that irradiated food is perfectly safe," Niemira said. "Do people want to approach the subject of irradiated food from a straight scientific standpoint -- as s...
Irradiated in Medical Technology

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...nge 2.4 to 7.4) for the 30 surviving patients. Although not a direct comparison, the results are superior to those observed following vaccination with irradiated tumor cells in 48 melanoma patients in a previous trial (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced rem...

Phase 1 Trial of Whole-Parasite Malaria Vaccine to Begin

...ia vaccine candidate. Unlike other malaria vaccine candidates, Sanaria's approach deploys a weakened form of the whole malaria parasite harvested from irradiated mosquitoes instead of small portions of the parasite. Having met the US Food and Drug Administration's (FDA) rigorous safety, sterility, purity, ...

Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects

...es investigating the preventative effects of Muscadine grape skin powder on irradiated mice. The mice consumed the powder two days before radiation and showed si... able to measure early gene defects in the stem cells in the bone marrow of irradiated mice. These cell changes precede cancer of the blood cells seen in leukemi...

St. Jude Study Finds Treatment With New Drug Might Make Tumor Cells More Sensitive to Therapy

...ts. This occurred not only in standard laboratory cells called HeLa cells, but also in human breast cancer cells. Overall, the response to CP466722 in irradiated cells was similar to that seen in cells lacking ATM, the team reported. The researchers also showed that CP466722 sensitized mouse cells to irradiatio...

Preclinical Study Presented at AACR Annual Meeting Shows Peregrine's Anti-PS Immunocytokines Can Generate Protective Immune Responses in a Highly Aggressive Breast Cancer Model

...ly aggressive cancer." In the study, researchers irradiated an aggressive and metastatic strain of breast canc...-cells. Mice were administered four doses of these irradiated immunocytokine-coated cells before receiving an im... or 80%, receiving prophylactic pre-treatment with irradiated breast cancer and immunocytokine cells did not dev...

Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer

...ole tumor cells that have been modified to secrete GM- CSF (granulocyte-macrophagecolony-stimulating factor), an immune stimulatory cytokine, and then irradiated for safety. GVAX is administered via intradermal injections on an outpatient basis. To date, over 600 patients have been treated with GVAX cancer immu...

A Functional Immune System Can Be Derived From Embryonic Stem Cells, Preliminary Study Finds

...Iowa, Taiwan, and Germany used HOXB4-containing ESCs to engraft the bone marrow and rescue mice that genetically lacked any immune system and had been irradiated to destroy their bone marrow. Only cells containing HOXB4 were able to engraft, rescue the mice, and produce blood cells long term. These engrafted ce...

Cancer Pioneer Reaches Key Agreement on Colon Cancer Drug OncoVAX(R)

...ars after surgical removal of the original tumor. Vaccinogen's scientists prepare a vaccine from the patient's own tumor. The cells are dissociated, irradiated to make them non-tumorigenic and administered to the patient by three weekly injections, starting four weeks after surgery. A booster vaccination is a...

Interim Analysis Supports Continuation of Cell Genesys' VITAL-1 Phase 3 Clinical Trial of GVAX Immunotherapy for Prostate Cancer

...hole tumor cells that have been modified to secrete GM-CSF (granulocyte-macrophage colony stimulating factor), an immune stimulatory hormone, and then irradiated for safety. GVAX is designed to be administered through intradermal injections on an outpatient basis. To date, over 600 patients have been treated wi...

Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche

...all of their worker bees. CCD has resulted in a loss of 50% to 90% of colonies in beekeeping operations across the United States. The observation that irradiated honeycombs from affected colonies could be repopulated with healthy bees, while non-sterilized combs could not, suggested an infectious basis for CCD....
Irradiated in Medical Products

Tipack (Sterilized) D1000

Description:... Packed conveniently in plastic-wrapped racks of 96 tips, Sterilized Diamond- Tips are ready to useno need to autoclave. Sterilized Diamond Tips are irradiated by gamma-rays for more efficient sterilization and are delivered with a certificate of sterilization, specifying the date of irradiation. Sterilized D...
Company:Gilson, Inc

Tipack (Sterilized) DL10

Description:... Packed conveniently in plastic-wrapped racks of 96 tips, Sterilized Diamond- Tips are ready to useno need to autoclave. Sterilized Diamond Tips are irradiated by gamma-rays for more efficient sterilization and are delivered with a certificate of sterilization, specifying the date of irradiation. Sterilized D...
Company:Gilson, Inc

Tipack (Sterilized) D10

Description:... Packed conveniently in plastic-wrapped racks of 96 tips, Sterilized Diamond- Tips are ready to useno need to autoclave. Sterilized Diamond Tips are irradiated by gamma-rays for more efficient sterilization and are delivered with a certificate of sterilization, specifying the date of irradiation. Sterilized D...
Company:Gilson, Inc

Finntip Filter Tips, 10mL

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 5mL

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 300 L

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 200ul ext

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 200ul

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 100ul ext

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific

Finntip Filter Tips, 100ul

Description:...A/RNA solutions, infectious materials, labelled samples, and other. For applications requiring absolute sterility, they are supplied in vacuum-sealed, irradiated tip racks....
Company:ThermoFisher Scientific
Irradiated in Medical Dictionary

Sterility

..... Sterility Assurance Tests. Service List/Test Codes. PHARM/BIOPHARM SERVICES ... A dose audit is a sterility test of samples which have been irradiated at a ... Shop for Sterility Testing in the Cameras section of Shop.com. Thousands of Brands. Hundreds of Stores. Female infertility causes...

Granulocyte

...by the presence ... Like all circulating granulocytes , basophils can be recruited out of the ... ... 9L inoculation, peripheral challenge with irradiated 9L cells and granulocyte ... localized infusion of granulocyte -macrophage colony-stimulating factor ... An analysis of neutrophil granulocy...
Irradiated in Biological News

First genetically-engineered malaria vaccine to enter human trials

..., the Walter Reed Army Institute for Research and the University of Maryland, had used knowledge from several decades ago when scientists proved that irradiated malaria parasites provide protection against subsequent malaria infection in animal models and humans in developing the vaccine. "Although vaccine...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

...nge 2.4 to 7.4) for the 30 surviving patients. Although not a direct comparison, the results are superior to those observed following vaccination with irradiated tumor cells in 48 melanoma patients in a previous trial (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced rem...

An easy way to find a needle in a haystack by removing the haystack

... Laser Desorption/Ionization (MALDI), wherein bio-molecules (e.g. proteins) are co-crystallized with a chemical substance called a matrix subsequently irradiated with a laser leads to the formation of protein ions which can be analyzed and detected. However, matrices used in the MALDI technique have a substa...

Lithium may help radiation target cancer, spare healthy tissue

...r Research found that lithium treatment protects cultured hippocampal neurons from radiation-induced cell death and improves cognitive performance in irradiated mice. But how lithium protects against radiation-induced damage is unclear. Radiation kills tumor cells by damaging their DNA, but it can also a...

Amniotic fluid may provide new source of stem cells for future therapies

...ing) potential in vivo. Therefore, adult mice were irradiated to destroy their capacity to produce blood cells a...es derived from AFKL cells appeared in most of the irradiated mice four weeks after the procedure. As expected, ...ntists continued to find AFKL-derived cells in the irradiated mice four months later, demonstrating the long-ter...

Single adult stem cell can self renew, repair tissue damage in live mammal

...as quantitative and kinetic analyses, Sacco and Blau tracked each transplanted stem cell as it rapidly proliferated and engrafted its progeny into the irradiated muscle tissue. The scientists then injured the regenerated tissue, setting off massive waves of muscle cell growth and repair, and subsequently sh...

Researchers discover atomic bomb effect results in adult-onset thyroid cancer

...ions for epidemiological risk analyses, early clinical diagnosis, and chemopreventive interventions," Hamatani said. He adds that there are several irradiated populations worldwide that have been shown to have an increase in thyroid cancer, and that children exposed to radioactive fallout from the 1986 Chern...

Molecular cubes in the sunlight

...water to date has been the lack of a robust catalyst that oxidizes water. In fact, the best known catalyst, which very effectively oxidizes water when irradiated with visible light, is a manganese-containing enzyme in the photosynthetic apparatus of living organisms. Robin Brimblecombe and Leone Spiccia at Mona...

Pesticide build-up could lead to poor honey bee health

...tion from a cobalt 60 source housed at Penn State's Breazeale Reactor, they irradiated the sheets of beeswax that beekeepers use as the structural foundation for ...using agents. However, it might be more efficient if the wax sheet supplier irradiated their product before sale to the beekeepers. Beekeepers cannot manage th...

Synergy between biology and physics drives cell-imaging technology

...roscopy, whereby optical microscopes are used to observe biological structures that have been tagged with fluorescent molecules that emit photons when irradiated with light of a specific wavelength, as these offer a resolution of at best 200 nanometres. Increasingly, biologists have turned to physicists for hel...
Irradiated in Biological Technology

First genetically engineered malaria vaccine to enter human trials

..., the Walter Reed Army Institute for Research and the University of Maryland, had used knowledge from several decades ago when scientists proved that irradiated malaria parasites provide protection against subsequent malaria infection in animal models and humans in developing the vaccine. "Although vaccine...

A breakthrough toward industrial production of fluorescent nanodiamonds

...ubsequent milling and purification steps. In this novel process, substitutional nitrogen-containing microdiamonds with defined atomic composition were irradiated using a high-energy electron beam and then annealed at high temperature (800 C) to create the desired photoluminescent centres in an intact diamond la...

A molecular ripcord for chemical reactions

...tached two polymer chains to these caps, creating a long chain with a metal complex in the center. These complexes were dissolved in a liquid that was irradiated with ultrasound, causing bubbles to form in the liquid. When these bubbles imploded, they created an extremely strong current that stretched the chain...

Amniotic Fluid May Provide New Source of Stem Cells for Future Therapies

...g) potential in vivo . Therefore, adult mice were irradiated to destroy their capacity to produce blood cells a...es derived from AFKL cells appeared in most of the irradiated mice four weeks after the procedure. As expected, ...ntists continued to find AFKL-derived cells in the irradiated mice four months later, demonstrating the long-ter...

Finesse Demonstrates TruFluor(TM) pH, a Single-Use Optical pH Sensor and Transmitter

...sting of a disposable sheath, an optical reader, and a transmitter. The single-use sheath can be pre-inserted in a disposable bioreactor bag port, and irradiated with the bag, in order to both preserve and guarantee the sterile barrier. All wetted materials of the sheath are USP class VI compliant. The opt...

Finesse Announces TruTorr(TM) Single-Use Pressure Sensor

...essure are then set, and the sensor is ready for immediate use. The single-use sensor can be pre-inserted in a disposable bioreactor bag port and irradiated with the bag. Since the sensor is pre-inserted the sterile barrier is never broken. All wetted materials of the sensor are USP class VI compliant; e...

Gene-engineered flies are pest solution

...ontrolling it is the sterile insect technique (SIT), whereby male flies are irradiated to induce reproductive sterility and then released into the wild, where com...t population. This radioactive version of the SIT has the drawback that the irradiated males are often less competitive than their wild brethren and so an awkward...

Finesse Introduces TruFluor(TM) DO, a Single-Use Optical Dissolved Oxygen Sensor and Transmitter

...sting of a disposable sheath, an optical reader, and a transmitter. The single-use sheath can be pre-inserted in a disposable bioreactor bag port, and irradiated with the bag, in order to both preserve and guarantee the sterile barrier. All wetted materials of the sheath are USP class VI compliant. According ...

Nanoswitches toggled by light

...ould be of use in nanoelectronic applications. The investigation showed that these crystals stretch out to become longer (but not wider) when they are irradiated with laser pulses in the microscope. If the irradiation is switched off, they contract back to their original size. This effect was most obvious when ...

Special coating greatly improves solar cell performance

...de with a very thin (5 to 10 nanometers thick) and smooth layer of nickel oxide. This material is an excellent conductor for extracting holes from the irradiated cell but, equally important, is an efficient blocker which prevents misdirected electrons from straying to the wrong electrode (the anode), which woul...
Irradiated in Biological Products

ELISA Strips from Santa Cruz Biotechnology, Inc.

Description:... Immulon 2HB ELISA strips, high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes. Flat bottom works well for reagent injection while providing t...
Company:Santa Cruz Biotechnology, Inc.

Immulon 2 HB 1x8 Strip assembled from Thermo Scientific

Description:... Immulon 2 HB 1x8 Strip assembled, C-bottom; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes....
Company:Thermo Scientific

Immulon 2HB from Thermo Scientific

Description:... Immulon 2HB, Flat Bottom, 50/Bx; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes....
Company:Thermo Scientific

96 Well Plate EB from Thermo Scientific

Description:... 96 Well Plate EB, RE bottom; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes. Guaranteed coefficient of variation (CVs)....
Company:Thermo Scientific
Irradiated in Biological Dictionary

Seminiferous tubules

... Results: In the seminiferous tubules of the sham-operated rat testes, many small ... Fine structure of seminiferous tubules from prenatally irradiated rats. ... What is seminiferous tubules ? Meaning of seminiferous tubules medical term. ... seminiferous tubules channels in the testis i...
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