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Intramuscular in Medical News

FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...noCrystal(R) Technology. Using this technology increases the rate of dissolution and enables the formulation of an aqueous suspension for once-monthly intramuscular administration. INVEGA SUSTENNA is manufactured by Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc, in the U.S. About J&JPR...

Tips from the journals of the American Society for Microbiology

... DNA vaccine including various immunoadjuvants (substances to improve the immune response) and monitored anti-GRP antibody levels in vaccinated mice. intramuscular injections induced high levels of specific antibodies against GRP as well as suppressed the growth of melanoma cells. Additionally, researchers intra...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

...with pcDNA"3.1D/V5-His-TOPO and purified these using Qiagen Endo-Free Giga Prep Kit. Eight groups of 6 week-old female BALB/c mice (13/group) received intramuscular injections of 100 micrograms of the vaccination preparation at days 2 and 9. At day 16, mice were induced with experimental SLE. Serum samples were ...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

...eridone is encapsulated in microspheres made of a biodegradable polymer, which are suspended in a water-based solution and administered to patients by intramuscular injection once every two weeks. RLAT is manufactured by Alkermes, Inc. and marketed by Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc....

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

...eridone is encapsulated in microspheres made of a biodegradable polymer, which are suspended in a water-based solution and administered to patients by intramuscular injection once every two weeks. RLAT is manufactured by Alkermes, Inc. and marketed by Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc....

Henry Ford Hospital: Unique Patient Study -- No Informed Consent

...use of the seizure is unknown, but some causes include previous trauma, stroke, tumor, or infection. The study, called RAMPART, will compare an intramuscular injection of midazolam (Versed) to an intravenous (IV) dose of lorazepam (Ativan). Both drugs are better than the most common current prehospital tre...

Gene Therapy Improves Diabetic Neuropathy in Study

...lyneuropathy, a disorder that commonly affects diabetics who've had the disease for many years, a new study finds. Researchers in Boston found that intramuscular injections of vascular endothelial growth factor (VEGF) gene may help patients with diabetic polyneuropathy. The study included 39 patients who receiv...

Testosterone Undecanoate Achieves and Maintains Normal Testosterone Levels in Hypogonadal Men With Five Injections Per Year, New Data Show

...SULTS This open-label study enrolled 130 hypogonadal men with serum testosterone levels below 300 ng/dL at study entry. NEBIDO was dosed as an intramuscular injection (750 mg) at baseline, at week four, and then every 10 weeks throughout the remainder of the 21-month study. Approximately 70 percent of pat...

Surveyed Specialists Foresee Greater Use of Parenteral Outpatient Therapy for the Treatment of Osteomyelitis

...overage of methicillin-resistant Staphylococcus aureus (MRSA) will increase, they foresee greater use of parenteral outpatient therapy (intravenous or intramuscular injection) for the treatment of osteomyelitis. Osteomyelitis is an infection of bone or bone marrow caused by bacterial infections. "Osteomyeliti...

New Approach to Progesterone Supplementation in ART Revealed in Recently Published White Paper

...in ART and that vaginal progesterone provides improved patient comfort over intramuscular (IM) progesterone without compromising pregnancy rates. The objective ...perspective. The vaginal progesterone formulations that were compared with intramuscular progesterone included: Crinone(R), Prometrium(R) oral tablets, compounded ...
Intramuscular in Medical Technology

BioCryst Announces Initiation of Phase II Study of Intramuscular Peramivir for the Treatment of Seasonal Influenza

BIRMINGHAM, Ala., July 10 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX ) today announced the initiation of a Phase II study of intramuscular (i.m.) peramivir for the treatment of seasonal influenza. The double-blind, placebo-controlled, parallel group Phase II tria...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...Crystal((R)) Technology. Using this technology increases the rate of dissolution and enables the formulation of an aqueous suspension for once-monthly intramuscular administration. INVEGA(R) SUSTENNA(TM) is manufactured by Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc, in the U.S. About J...

PharmAthene Submits SparVax(TM) Regulatory Strategy to FDA

... About SparVax(TM) SparVax(TM) is a novel second generation recombinant protective (rPA) anthrax vaccine being developed for administration by intramuscular injection. Phase I and Phase II clinical trials involving more than 700 healthy human subjects have been completed and showed that SparVax(TM) appear...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...eridone is encapsulated in microspheres made of a biodegradable polymer, which are suspended in a water-based solution and administered to patients by intramuscular injection once every two weeks. RISPERDAL(R) CONSTA(R) is manufactured by Alkermes, Inc. and marketed by Janssen, Division of Ortho-McNeil-Janssen Pha...

BioCryst Provides Peramivir Update and Reports First Quarter 2009 Financial Results

...vity to peramivir and all ten isolates were susceptible to peramivir. intramuscular Peramivir Phase 2 Study Results for Seasonal Influenza BioCryst also announced preliminary results from its Phase 2 study of intramuscular (i.m.) peramivir for the treatment of seasonal influenza. While the study d...

Nobilon Advances First Vaccine Into Human Trials - Intranasal Influenza Vaccine Begins Phase I Clinical Development

...evalence, but is up to 80% effective in preventing death. Nevertheless, current inactivated influenza vaccines have limitations and are underutilized. intramuscular vaccination with needles is an important barrier for the acceptance of annual influenza vaccination, which may be overcome by intranasal application. ...

FDA Accepts Complete Response Submission to New Drug Application for NEBIDO(R)

...rug Administration (FDA) has accepted for review the complete response submission to the new drug application for NEBIDO(R) (testosterone undecanoate) intramuscular injection, an investigational testosterone preparation for the treatment of male hypogonadism. FDA is targeting September 2, 2009 as the action date ...

Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections

...being studied in hospitalized and outpatient influenza, utilizing either an intramuscular or intravenous formulation. A Phase 2 trial in outpatient influenza is cur...the Phase 2 clinical trials of peramivir did not receive adequate dosing by intramuscular injection may not be correct, that HHS and the Food & Drug Administrati...

Reproductive Partners Participates in New IVF Progesterone Delivery System Study

...a national study to explore new IVF progesterone delivery systems replacing intramuscular injections. LOS ANGELES, Jan. 12 /PRNewswire/ -- Reproductive Partner..., multi-center study exploring new progesterone delivery systems to replace intramuscular injections. Patients going through in vitro fertilization (IVF) often des...

Fertility Physicians of Northern California Researchers Test New Forms of Progesterone Medication for Luteal Support During IVF

... Calif., Jan. 5 /PRNewswire/ -- Women undergoing in vitro fertilization (IVF) require progesterone medication to help support early pregnancy, but the intramuscular injections for some forms of this medication can be painful for patients. Formulations of progesterone medication which can be administered by subcut...
Intramuscular in Medical Products

Medtronic Model 4351 Lead (Enterra™ Therapy)

Description:... The new 4351 intramuscular Lead is a unipolar lead intended for use with an implantable neurostimulator. The 4351 lead has a ski needle design for easier use with laparoscopic p...
Company:Medtronic Gastroenterology
Intramuscular in Medical Dictionary

Intramuscular

Intramuscular (or IM) injection is the injection of a substance directly into a muscle. In medicine, it is one of several alternative methods for the administration of medications . It is used for particular forms of medication that are administered in small amounts. Depending on the chemical...

Parenteral

... A.S.P.E.N. American Society for Parenteral and Enteral Nutrition ... Injection/ parenteral . Subcutaneous · Intravenous · intramuscular · Intrathecal · Intracavernosal ... Parenteral nutrition (PN) is feeding a person intravenously, bypassing the usual process of eating and dig...

Lymphatic system

...lymphatic system and what exactly do they do? ... The second function of the lymphatic system is the absorption of fats and fat ... An intramuscular system of lymphatic vessels that parallels the ... Guyton AC: The lymphatic system , interstitial fluid dynamics, edema, and pulmonary fluid...

Hemangioma

...her infantile hemangioma (birthmark) in the lower lip. ... Hemangioma and hemangioma -like vascular tumors and vascular and lymphatic ... intramuscular hemangioma case treated with a wide surgical excision ... hemangioma n. , pl. -mas also -mata . A benign skin lesion consisting of den...

Gamma globulin

...ons ... Gamma globulin is the component of human blood which ... But intramuscular gamma globulin , which has been available for ... Immune globulin ...ulin was measured by the zinc sulfate turbidometric technique as ... intramuscular gamma globulin , which has been available for ... first tried gamma ...
Intramuscular in Biological News

Tips from the journals of the American Society for Microbiology

... intranasally with H1N1 VLPs mice were highly protected against a lethal challenge with both the 1918 and H5N1 virus. In contrast, mice receiving two intramuscular immunizations of 1918 VLPs were only protected against the 1918 viral challenge. Mucosal vaccination with 1918 VLPs induced higher levels of cross-re...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

...act, by up to 50 percent. "This work demonstrates a novel non-invasive mesenchymal stem cell (MSC) therapeutic regimen for heart failure based on an intramuscular delivery route," said Techung Lee, Ph.D., UB associate professor of biochemistry and senior author on the paper. Mesenchymal stem cells are found i...

Tips from the Journals of the American Society for Microbiology

...avalent dengue virus vaccine by combining genes and proteins from all four dengue virus types as well as incorporating an adenovirus agent. Following intramuscular vaccination, rhesus macaques showed high antibody levels that neutralized all four of the dengue virus types. To further test the sustainability of t...

New technology may prevent vitamin B12 deficient seniors and vegetarians from needing injections

... TORONTO, Canada (June 17, 2008) For those patients who receive the nearly 40 million intramuscular injections per year to treat their B12 deficiency, a new oral option may soon exist. According to the National Institutes of Health, vitamin B12 d...

New computer applications allow to classify Iberian pig meat automatically

...ybrid breed, Iberian pig, lamb, cow of the Galician Blonde breed, Kobe ox and pigeon. The designed application permitted to quantify automatically the intramuscular connective tissue and the retraction of the muscular fibres in images taken by a system or artificial vision coupled to a microscopy. Second, the stud...

Testosterone replacement theraphy beneficial in men 60 and older

... of enrollment. (Normal limits are considered 250-800.) Each was enrolled in one of three double-blinded groups: (1) those receiving continuous weekly intramuscular injections of testosterone (100 mg testosterone-enanthate) for the entire five month period (TE; n=4); (2) those receiving weekly testosterone every o...

Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength

... one day. Over three months, says Dr. Trappe, the chronic consumption of ibuprofen or acetaminophen during resistance training appears to have induced intramuscular changes that enhance the metabolic response to resistance exercise, allowing the body to add substantially more new protein to muscle. The amount o...

Peramivir protects mice from lethal H5N1 infection

...f peramivir (intramuscular injections alone versus intramuscular injections followed by oral administration) and fr... 100 percent survival among 10 infected mice given intramuscular injections of peramivir daily for eight days. The ...he treatment for eight days. In contrast, a single intramuscular injection resulted in a 40 percent survival rate, ...

'Smart' genetic therapy helps the body to heal itself

...nternational Duchenne Parent Projects, and governmental and charity funds, Dr. J. van Deutekom and her team will soon start a clinical trial, based on intramuscular injection of a single dose of an anti-sense drug that induces the skipping of exon 51 from the DMD gene. Six Dutch DMD patients aged between 8 and 16...

Plant-derived vaccines safeguard against deadly plague

...because we've come to the realization that plants also have the potential for the production of antigens that can be purified and delivered by typical intramuscular or subcutaneous injections -- the way most vaccines are normally given," said Mason, an associate professor in the School of Life Sciences. "This new ...
Intramuscular in Biological Technology

Delivery of pCMV-S DNA Using the Helios Gene Gun System Is Superior to Intramuscular Injection in Balb/c Mice

Andrew Conn, Lindy Durrant, and Ian Spendlove, Cancer Research Campaign Academic Unit, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK Introduction Gene gun immunization through the skin is a reliable and reproducible ...

PharmAthene's 2nd Generation rPA Anthrax Vaccine, SparVax(TM), Completes FDA Regulatory Strategy Review

... About SparVax(TM) SparVax(TM) is a novel second generation recombinant protective (rPA) anthrax vaccine being developed for administration by intramuscular injection. This product employs modern vaccine technology to provide a highly purified and well characterized modern vaccine for intended use by the ...

Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine

...izations and 36,000 deaths in the U.S. each year. The vaccine is currently in Phase 2 clinical testing. In this study, mice and ferrets received intramuscular injections of VLP vaccine which induced HAI antibodies against all three influenza strains represented in the vaccine and against a variety of drifted...

Flu vaccine given in microneedle skin patches proves effective in mice

...he skin and after a few minutes, the vaccine coating dissolved off within the skin. The coated microneedle immunizations were compared to conventional intramuscular hypodermic injections at the same dose in another group of mice. The researchers found that the microneedle vaccinations induced strong immune res...

NOVAVAX Announces Publication of a Preclinical Study Demonstrating that a Virus-like Particle Vaccine Provided Protection Against Highly Pathogenic H1N1 and H5N1 Influenza Strains

... ferrets were vaccinated with VLPs by one of two routes: either by standard intramuscular injection or by administering a small drop of the VLP vaccine in the nose (...ax has shown in clinical trials that an H5N1 VLP candidate vaccine given by intramuscular injection is well tolerated and immunogenic in humans. Preclinical researc...

BioCryst Reports Fourth Quarter and Year End 2008 Financial Results and Provides Corporate Update

...to be received from HHS related to costs incurred in the Phase 3 program of intramuscular (i.m.) peramivir for outpatient influenza. The Company initiated this prog...ects in the Phase 2 clinical trial of peramivir received adequate dosing by intramuscular injection for which HHS or the Food & Drug Administration (FDA) may not...

Sangamo BioSciences Reports Fourth Quarter and Full Year 2008 Financial Results

...observed in Sangamo's SB-509 trials in DN. The study is a randomized, repeat-dosing, open-label, multi-center study designed to evaluate the effect of intramuscular administration of SB-509 on the progression of the disease in subjects with ALS. In addition to gathering data on safety and tolerability of SB-509, t...

BioCryst to Present at the J.P. Morgan 27th Annual Healthcare Conference

... statements contained herein include that our belief that many subjects in the Phase 2 clinical trials of peramivir did not receive adequate dosing by intramuscular injection may not be correct, that HHS and the Food & Drug Administration (FDA) may not agree with our analysis, that HHS may further condition, r...

BioCryst to Present Three Posters During the 50th American Society of Hematology Annual Meeting and Exposition

... statements contained herein include that our belief that many subjects in the Phase 2 clinical trials of peramivir did not receive adequate dosing by intramuscular injection may not be correct, that HHS and the Food & Drug Administration (FDA) may not agree with our analysis, that HHS may further condition, r...

Sangamo BioSciences Announces Results From Diabetic Neuropathy Clinical Trial SB-509-601

...or neuropathy in the legs. 110 subjects were enrolled into the trial. Subjects were randomized to one of two groups. The larger group was treated by intramuscular injection of 60 mg of SB-509 (30 mg of SB-509 per leg) into the lower limb every two months. The remaining group received an equal volume of placebo o...
Intramuscular in Biological Products

15(S)-15-methyl Prostaglandin F2alpha from Cayman Chemical

Description:...acient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys....
Company:Cayman Chemical
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