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Intradermal in Medical News

1st EMEA application filed for product using innovative intradermal microinjection system BD Soluvia

Franklin Lakes, NJ, USA (February 13, 2008) -- Sanofi Pasteur, the vaccines division of sanofi-aventis Group, has submitted the first application in Europe to deliver a vaccine using BD Soluvia, the innovative microinjection system developed by BD (Becton, Dickinson and Company). The submission ...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...y genetically modifying autologous antigen-loaded dendritic cells to express an inducible costimulatory CD40 (iCD40) receptor. Twenty-four hours after intradermal administration, these genetically modified dendritic cells are activated in draining lymph nodes by intravenous administration of AP1903, a small-mole...

Sanofi-aventis Announces Good First-quarter 2009 Performance

...Intanza (R) , the first influenza vaccine to be administered using a novel intradermal microinjection system. The benefits of this vaccine, in particular its conv...boembolic events after abdominal surgery; -- the intradermal influenza vaccine Intanza(R) in Europe, and the pandemic inf...

TorreyPines' NGX426, an Oral AMPA/Kainate Receptor Antagonist, Meets Primary Endpoints in Reducing Capsaicin-Induced Pain in Healthy Subjects

...rom normally non-painful stimuli to the skin) compared to placebo following intradermal injections of capsaicin in a human experimental model of cutaneous pain, hy...ale subjects. Using a three-period cross-over design, subjects received two intradermal injections of capsaicin at 30 minutes and 120 minutes after administration ...

TorreyPines Therapeutics Announces Management Change and Second Quarter 2008 Financial Results

...of NGX426 on hyperalgesia, an abnormally increased pain state, and allodynia, pain resulting from normally non-painful stimuli to the skin, induced by intradermal injections of capsaicin. This study, if successful, will allow the company to further benefit from of the versatility of NGX426. -- Presented data f...

Therapeutic DNA Vaccine Company Inovio Biomedical Reports Second Quarter 2008 Financial Results

... plasmid DNA-based universal influenza vaccine candidates using the company's proprietary electroporation delivery technology and, specifically, a new intradermal device, showed that 100% of immunized mice given a lethal challenge of highly pathogenic H5N1 influenza virus (A/Vietnam/1203/04) survived and showed ...

Johnson & Johnson Reviews Growth Strategies for Medical Devices & Diagnostics and Consumer Businesses

...Ethicon's PRINEO(TM) Skin Closure System is a new product designed to reduce skin closure time an average of 75 percent compared to standard intradermal suturing in procedures such as body contouring, which some patients choose after having experienced significant weight loss. PRINEO was lau...

Anesiva Announces Hiring of Sales Force for FDA-Approved Product Zingo(TM)

...s hospital-focused sales force to support the commercial introduction of Anesiva's FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, in the second quarter of 2008. "By adding a sales force and sales leadership team with substantial hospital sales experience to ou...

Anesiva Announces Upcoming Webcasts and Conference Participation

...cialization of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in Anesi...

Anesiva to Announce Third Quarter 2007 Financial Results and Host Webcast Conference Call on November 1, 2007

...cialization of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in Anesi...
Intradermal in Medical Technology

Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

...scle. The proposed KI/SMI study would mark the first human test of a Vaxfectin(R)-formulated vaccine delivered by needle-free injection into the skin. intradermal delivery by needle-free injection and use of the Vaxfectin(R) adjuvant may increase the immune responses to the vaccine. About Vaxfectin(R) Vaxfec...

Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

...e proposed Karolinska/SMI study would mark the first human test of a Vaxfectin(R)-formulated vaccine delivered by needle-free injection into the skin. intradermal delivery by needle-free injection and use of the Vaxfectin(R) adjuvant may increase the immune responses to the vaccine. About Vaxfectin(R) Vaxfec...

TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel

...of NGX426 on hyperalgesia, an abnormally increased pain state, and allodynia, pain resulting from normally non-painful stimuli to the skin, induced by intradermal injections of capsaicin. The primary endpoint is subject self-report of spontaneous pain following the injection of capsaicin. "We believe there is ...

Halozyme Therapeutics Presents Findings on Combinations of rHuPH20 Enzyme With Bisphosphonates at the American Association for Cancer Research Conference

...us infusion. Key findings from the study were as follows: -- In rodent intradermal models, injection of bisphosphonates without rHuPH20 created injection...uration, and ulceration in a concentration dependent manner. -- In rodent intradermal models, the maximal concentration of bisphosphonates that could be adm...

Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer

...te GM- CSF (granulocyte-macrophagecolony-stimulating factor), an immune stimulatory cytokine, and then irradiated for safety. GVAX is administered via intradermal injections on an outpatient basis. To date, over 600 patients have been treated with GVAX cancer immunotherapies in Phase 1 and Phase 2 clinical trial...

Interim Analysis Supports Continuation of Cell Genesys' VITAL-1 Phase 3 Clinical Trial of GVAX Immunotherapy for Prostate Cancer

...cyte-macrophage colony stimulating factor), an immune stimulatory hormone, and then irradiated for safety. GVAX is designed to be administered through intradermal injections on an outpatient basis. To date, over 600 patients have been treated with GVAX cancer immunotherapies in Phase 1 and Phase 2 clinical trial...

Anesiva Announces Pivotal Phase 3 Trial of Zingo(TM) Meets Primary Endpoint and Significantly Reduces Venous Access Pain in Adults

...n those treated with Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system compared to placebo (p= 0.003). Patients received Zingo or...DA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access p...

Anesiva Defines Regulatory Pathway for Adlea with FDA

...cialization of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in Anesi...

Anesiva Initiates Phase 2 Trial with Adlea(TM) for Pain Relief Following Total Hip Replacement Surgery

...cialization of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in Anesi...

Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery

...cialization of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in Anesi...
Intradermal in Medical Dictionary

Intradermal

Online Medical Dictionary and glossary with medical definitions ... Intradermal tests are much used to diagnose allergy and to test cellular immunity. ... intradermal synonyms. intradermal usage examples and intradermal quotes. ... intradermal definition. intra·der·mal (in′trə dʉr...

Microorganism

...ormation on Microorganism from Biology-Online.org dictionary. ... Microorganism to man evolution--not natural selection or ... ... model, the intradermal tests) . This microorganism has been found capable of ... levels on populations of microorganisms , activities of urease, dehydrogenase, ... O...

Hyposensitization

...ictionary.com with free online dictionary, ... hyposensitization . hyposensitize. hyposensitized. hyposensitizing ... Allergy testing, including intradermal testing, and immunotherapy ( hyposensitization ) in dogs. ... The hyposensitization injections have had good results in ... Hyposensitization ...

Coccidioidin

...erance to coccidioidin lasted for 3 to 6 months. ... The adoptive transfer of coccidioidin sensitivity to tolerant animals by ... 2. Repeated intradermal coccidioidin testing of reactors with weak or latent ... allergic inflammatory response to coccidioidin need not necessarily be ... Coccidio...
Intradermal in Biological Technology

Helix BioPharma Receives Approval to Initiate Phase II Pharmacokinetic Clinical Study of Topical Interferon Alpha-2b in Patients with Low-Grade Cervical Lesions

...y favored due to the fact that conventional administration requires painful intradermal injection by a medical professional. Furthermore, intradermal injection is restricted to visible lesion administration, while HPV infecti...

First Multiple Dose Clinical Trial of TorreyPines Therapeutics' Oral Compound NGX426 Demonstrates Compound Is Safe and Well-Tolerated

...eralgesia (abnormally increased pain state) and allodynia (pain resulting from normally non-painful stimuli to the skin) compared to placebo following intradermal injections of capsaicin in a human experimental model of cutaneous pain, hyperalgesia and allodynia. In order to pursue the Phase II clinical dev...

Vaxfectin(R)-formulated Measles DNA Vaccine Could Address Unmet Need for Infants

... peaked at Week 5, and remained well above the accepted protection threshold for more than one year, with no difference noted between intramuscular or intradermal routes of administration. In the infant macaques, neutralizing antibody levels exceeded the accepted protection threshold prior to the second injectio...

Anesiva Announces First Quarter 2008 Financial Results

...nded March 31, 2008 and provided an update on its commercialization activities for FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, as well as clinical development milestones for Adlea(TM), the company's long-acting, localized, non-opioid analgesic drug candidate....

Anesiva Announces Expansion of Zingo Agreement in Europe

...d distribution agreement for Zingo(TM) with Sigma-Tau SpA to include additional European countries. Zingo (lidocaine hydrochloride monohydrate) powder intradermal injection system is approved in the United States to provide topical local analgesia prior to peripheral IV insertions or blood draws in children thre...

Anesiva Announces New Zingo Marketing and Distribution Agreement

...keting and distribution agreement, with Green Vision Company, for several Middle Eastern countries. Zingo (lidocaine hydrochloride monohydrate) powder intradermal injection system is approved in the U.S. to provide topical local analgesia prior to peripheral IV insertions or blood draws in children three to 18 y...

ProMetic presents preclinical data for prostate and pancreatic cancer at the AACR Meeting

...non, ProMetic's Director of Research and Development, Biology, presented preclinical data on the PBI-0110 alone and in combination with gemcitabine in intradermal and orthotopic pancreatic cancer. The study showed that PBI-0110 alone significantly inhibited pancreatic tumor growth in mouse models by as much as 5...

Anesiva Announces Fourth Quarter and Year-End 2007 Financial Results and Provides 2008 Outlook

...ishments and outlined its objectives for 2008 based on commercialization plans for FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, as well as clinical development milestones for Adlea(TM), the company's long-acting, localized, non-opioid analgesic drug candidate....

Microfabrica Introduces Set of Miniature 'Building Blocks' for Minimally-Invasive Medical Devices

... for distal protection or retrieval, especially in tortuous vessels, due to its unusual flexibility. Meanwhile, robust, hollow microneedles can enable intradermal and precision drug delivery systems." EFAB technology differs from conventional manufacturing processes in several ways. By applying to mechanical d...

Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM)

...and launch plans for Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access p...DA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access p...
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