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Lack of enzyme turns fat cells into fat burners

Lack of the enzyme, acetyl CoA carboxylase 2or ACC2, appears to turn the adipose or fat cells of mice into fatburners, explaining in part why the animals can eat more and weigh lessthan their normal counterparts, said Baylor College of Medicineresearchers.The report that appears online today in the Proceedings of the NationalAcademy of Sciences. "Westudied the fat cells in these mic...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

Few things about growing older are asinevitable and obvious as “going gray,?yet scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a report posted today on the Web site of the journal Science,researchers from Dana-Farber Cancer Institute and Children’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating th...

Transport System Smuggles Medicines Into Brain

Parrots, long a favorite pet animal, are attractive to owners because of their vibrant colors. But those colors may mean more to parrots than what meets the eye. For more than a century, biochemists have known that parrots use an unusual set of pigments to produce their rainbow of plumage colors, but their biochemical identity has remained elusive. Now, an Arizona State University researc...

UCLA scientists transform HIV into cancer-seeking missile

Camouflaging an impotent AIDS virus in new clothes enables it to hunt down metastasized melanoma cells in living mice, reports a UCLA AIDS Institute study in the Feb. 13 online edition of Nature Medicine. The scientists added the protein that makes fireflies glow to the virus in order to track its journey from the bloodstream to new tumors in the animals' lungs. "For the past 20 years, ge...

New insight into people who 'see' colors in letters and numbers

People with a form of synesthesia in which they see colors when viewing letters and numbers really do see colors, researchers, led by Edward M. Hubbard of the University of California San Diego, have found. What's more, functional magnetic resonance imaging (fMRI) of their brains reveals that they show activation of color-perception areas. The researchers said their findings lend support t...

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EasyCode Macintosh Software from AutoMate Scientific, Inc

Description:Expand the computing power of your ValveBank system! Program your valve and TTL on-off sequences with a Macintosh computer using graphic 'click-and-drag' timebars. Save and load unlimited programs to disk, print out program listings, then download your programs into the ValveBank's memory in one simple step. EasyCode is used for programming before -- not during -- an experiment, leavi...
Company:AutoMate Scientific, Inc

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Efficiently Insert Unique Restriction Sites into Plasmid Vectors

Stratagene A 28-base insertion was introduced into a plasmid vector using theQuikChange site-directed mutagenesis kit.* Theinsertion created three unique restriction enzyme digestion sites. Plasmid DNAisolated from 9 o...

Transfection of Green Fluorescent Protein into Human Adrenalcarcinoma Cells

Department of Cell Biology, Neurobiology, and Anatomy University of Cincinnati College of Medicine, Cincinnati, OH 45267 Transfection of mammalian cell lines is enhanced by the use ofliposome-based reagents. Here we compare the transfection e...

Deliver siRNAs Into Primary Cells

Deliver siRNA into primary cells, cells grown in suspension, and other difficult-to-transfect cells Maintain high cell viability under a wide range of conditions Optimize electroporation of your...

Selecting siRNA Sequences to Incorporate into the pSilencer Vectors

The first step in preparing a plasmid for siRNA experiments is to identify target sequences in the gene of interest that are susceptible to siRNA-induced degradation. We have found that a little more than half of the siRNAs provide at least a 50% reduction in target mRNA levels and approximately 1 out of 4 siRNAs...

A Robust LC/MS/MS Method for the Quantitation of Very Long Chain Fatty Acids for Research into the Characterization of Peroxisomal Disorders

The peroxisome is a cellular organelle that plays an important role in a number of functions, including the beta-oxidation of very long chain fatty acids (VLCFA). Peroxisomal disorders are characterized by impaired, reduced or total absence of peroxisomes in cells, which can result in the accumulation of VLCFAs, such as tetracosanoic and hexaco...

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Clinton's new problem - Is the outgoing American president suffering from skin cancer?

The outgoing U.S. president Bill Clinton will be remembered as one of the most controversial presidents ever. He created history by becoming the first American president in history to be impeached by the House of Representatives. Only because he managed to win at the senate did he save himself and his country further damage. He has been the center of many burning controversies throughout...

Parke-Davis (India) runs into rough weather – Court orders attachment of asset

The global merger between Warner-Lambert and Pfizer on the Indian front has run into rough weather due to the legal problems faced by Warner-Lambert’s subsidiary Parke-Davis (India). A local court in Hyderabad has ordered the attachment of its assets located in the city. The vacation court of the Ranga Reddy district civil courts has ordered attachment of plant and machinery of Parke-...

Biotechnology industry expected to grow into a three billion dollar industry by 2002

The biotech products market in India is expected to grow into a three billion dollar industry by 2002 according to a Rabo India finance report. The big leap is expected to triple the industry's size from its 1999 value of one billion dollars. Biogenerics, biopharmaceuticals, agriculture, food and nutrition sectors are all poised for the big leap, both nationally and internationally. Th...

New scalpel probes into cancer

A smart scalpel which is able to detect the presence of cancer cells beneath layers skin, blood and muscle have been developed by US researchers. The bottle-top sized microcavity laser developed by the US department of Energy will enable surgeons to operate more accurately on tumours without cutting large amounts of tissue.// This device could detect which cells were cancerou...

Lancing tumours into the body

A team of micromachine experts report this week that they have developed tiny spinning screws that could swim along veins, ferrying drugs to infected tissues, or even burrow into tumours to kill them off with a hot lance.Kazushi Ishiyama at Tohoku University in Japan has designed swimming micromachines based on cylindrical magnets.// Measuring 8 milllimetres long and less than a millim...

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MacIntosh English Profile Conventional Laryngoscopes

Description:CCR Medical conventional laryngoscopes....
Company:CCR Medical

MacIntosh American Profile Conventional Laryngoscopes

Description:CCR Medical conventional laryngoscopes....
Company:CCR Medical

MacIntosh English Profile Fiberoptic Laryngoscopes

Description:CCR Medical fiberoptic green system laryngoscope handles. OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
Company:CCR Medical

MacIntosh American Profile Fiberoptic Laryngoscopes

Description:CCR Medical fiberoptic green system laryngoscope handles. OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
Company:CCR Medical

German Style MacIntosh Fiber Optic Blade Laryngoscopes

Description:German Style MacIntosh Fiber Optic Blade Laryngoscopes...
Company:CCR Medical

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Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics

PHILADELPHIA, July 3, 2007 ? Researchers in Slovakia havebeen able to derive mesenchymal stem cells from human adipose, orfat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack smalltumor metastases that evade current detection techniques andtreatments, the researchers...

Stanford Researchers Track Human Stem Cells Transplanted Into Rat Brain

STANFORD, Calif.--(BUSINESS WIRE)--Jun 4, 2007 - Researchers at theStanford University School of Medicine have illuminated the pathtaken by human neural stem cells that were transplanted into thebrains of rats and mice, and found that the cells successfullynavigate toward areas damaged by stroke. The research group placed miniscule particles of iron insidestem cells to act as cellular bea...

FDA Announces Results of Investigation Into Illegal Promotion of OxyContin by The Purdue Frederick Company, Inc.

Company Misrepresented Prescription PainReliever to Health Care Professionals ROCKVILLE, Md., May 10, 2007-The U.S. Food and DrugAdministration's (FDA) Office of Criminal Investigations (OCI)announced today that The Purdue Frederick Company, Inc. has agreedto pay more than $700 million to resolve criminal charges and civilliabilities in connection with...

Schepens Scientists Identify Key to Integrating Transplanted Nerve Cells Into Injured Tissue

Discovery promises to make retina, spinal cord and other centralnervous system transplants possible BOSTON, April 26, 2007 /PRNewswire/ -- Scientists at theSchepens Eye Research Institute, an affiliate of Harvard MedicalSchool, have identified a key mechanism for successfullytransplanting tissue into the adult central nervous system. Thestudy found that a molecule known as MMP-2 (which is...

Callisto Intends to Move Guanilib into Clinical Trials in Ulcerative Colitis

Announces Positive Data in Animal Models of Ulcerative Colitis NEW YORK, April 05, 2007 /PRNewswire-FirstCall/ -- CallistoPharmaceuticals, Inc. , a developer of new drug treatments in thefight against cancer and other major health threats, announcedtoday additional data confirming efficacy of Guanilib, afirst-in-class compound currently being developed for the treatmentof inflammatory bow...

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European Prospective Investigation into Cancer and Nutrition

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into at Medicine Dictionary

Lactose intolerance

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Intoxication

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Heat intolerance

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Food intolerance

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Cold intolerance

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