An efficient approach to monitor gastrointestinal microflora changes
...sses this question. The research team led by Prof. Li from School of Pharmacy of Shanghai Jiao Tong University, China, used enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR), which is a PCR-based molecular method, and utilizes oligonuleotides targeting short repetitive sequences ERIC which are disp...What are the predominant bacilli in the intestines ducklings infected with S. enteritidis?
... The enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR) method has been used to fingerprint the kinetics of microbial community of fecal samples of ducklings orally infected with S....Genomatix integrates genome-wide open chromatin from next generation sequencing
... correlation studies show that the majority of open chromatin is located in intergenic and intronic regions. Additionally a strong correlation is shown between...nt handle on localizing and elucidating the role of enhancers/repressors in intergenic regions. Dr. Seifert continues: Several in-house projects which we condu...Genetic Variations In Detoxifying Genes Lead To Lou Gehrig's diseases
...the chromosome region encompassing PON2-PON3 were strongly associated with sporadic ALS. "Thus, single nucleotide polymorphism genotyping in the intergenic regions of the PON gene cluster, and replication, gene expression, gene-gene interaction and PON serum/enzymatic studies may help elucidate the comple...Study finds DNA barcoding requires caution without closer examination
...include a section of the nuclear ribosomal DNA: the internal non-transcribed spacer region (ITS); and various plastid regions to include the trnH-psbA intergenic spacer and the plastid genes rpoC1, rpoB, and matK. Spooner tested the utility of barcoding in a well-studied but complex plant group, wild and cu...2009 Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research
...d his colleagues have discovered a new class of molecule that may have important implications for understanding and treating cancer. lincRNAs large intergenic non-coding RNAs are unique from other materials in cells, however, their precise function remains unknown. Dr. Rinn aims to decipher the workings of...BIDMC scientist John Rinn, Ph.D., receives Damon-Runyon Rachleff Innovation Award
...We're delighted to once again be funding such innovative ideas." Rinn's work focuses on a class of molecule known as lincRNAs, an acronym for large intergenic non-coding RNAs. Based on earlier research that identified the first lincRNA a molecule called HOTAIR that plays a major role is establishing the di...New gene-silencing pathway found in plants
...tches of DNA that lie between genes, the so-called intergenic regions. Biologists have long been baffled by thi...ined that Pol V was indeed hard at work within the intergenic region. In this space between genes, Pol V makes ...nal part of the genome, since transcription of the intergenic regions is necessary to keep potentially harmful g...Researchers develop new self-training gene prediction program for fungi
...ic mathematical model called the Hidden Markov Model to pinpoint the boundaries between coding sequences (exons) and non-coding sequences (introns and intergenic regions). Most introns start from the dinucleotide guanine-thymine (abbreviated GT) and end with the dinucleotide adenine-guanine (abbreviated AG)...Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
...s. The researchers found that genes of these organisms are more stable than intergenic regions near their 3?end. In addition, introns (internal non-coding regions...ell," says Stoynov. The researchers also observed that, in contrast to intergenic regions, genes have more stable sense RNA/DNA duplexes than potential antis...Variations in detoxifying genes linked to Lou Gehrig's disease
...n the chromosome region encompassing PON2-PON3 were strongly associated with sporadic ALS. "Thus, single nucleotide polymorphism genotyping in the intergenic regions of the PON gene cluster, and replication, gene expression, gene-gene interaction and PON serum/enzymatic studies may help elucidate the comple...Tandem transcripts team together
... They found that genes involved in TIC events often reside closer together than other gene pairs in the genome. In addition, they discovered that the intergenic sequences of TICs were processed via the same standard eukaryotic splicing machinery that removes introns from RNA transcripts. Following a similar...Whole genome fine map of rice completed
...genes are unique to any one of the two strains. Even though the genetic difference between the two strains is small, there are large differences in intergenic regions. The study also analyzed the duplication history of the rice genome. Eighteen pairs of apparent duplications were discovered, covering 65.7% o...