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Intercalation in Medical News

Sunesis Pharmaceuticals Presents Nonclinical Data on SNS-595 at the Annual Meeting of the American Association for Cancer Research

... presented today at the AACR Annual Meeting in three posters: -- SNS-595 is a potent anti-tumor agent that has a dual mechanism of action: DNA intercalation and site-selective topoisomerase II poisoning [Abstract #1860] -- Ex vivo activity of SNS-595 against biopsies of acute myeloid leukemia, tri...

Vet school in £10.7 million initiative to boost veterinary research training

...pecialist postgraduate training in laboratory animal medicine. In addition, leading to these centrepiece awards will be 175 Vacation Scholarships, 175 intercalation Awards, support for 5 Summer Schools, and 9 one-year Research Entry Scholarships. To coincide with the announcement of the new programme, the Royal...
Intercalation in Medical Technology

Sunesis Pharmaceuticals Initiates Phase 2 Clinical Trial of Voreloxin (SNS-595) in Acute Myeloid Leukemia

...se II, resulting in replication-dependent, site- selective DNA damage, irreversible G2 arrest and rapid apoptosis. The topoisomerase II-associated DNA intercalation and DNA damage produced by voreloxin show greater selectivity for proliferating cells. In nonclinical evaluations, voreloxin demonstrates broad and ...

Sunesis Pharmaceuticals to Present Non-Clinical Data at the Annual Meeting of the American Association for Cancer Research

...ngoing. SNS-595 Poster Presentations Monday, April 14, 2008 -- SNS-595 is a potent anti-tumor agent that has a dual mechanism of action: DNA intercalation and site-selective topoisomerase II poisoning Session: Stress Responses Abstract #1860 8:00 a.m. - 12:00 p.m. Exhibit Hall B-F, San Diego ...
Intercalation in Biological Technology

Real-Time PCR: General Considerations, Rev A

...polymerase Primer concentration (100500 nM) An asymmetric primer concentration may be helpful Fluorescent probe or intercalation dye concentration Conditions Optimization of the following amplification conditions will be required to obtain the m...
Intercalation in Biological Dictionary

Intercalation

In chemistry, intercalation is the reversible inclusion of a molecule (or group) between two other molecules (or groups). Examples include DNA intercalation and in graphite intercalation compounds. Intercalation is the insertion of a leap day, week or month into some calendar years t...

Dorsal

... dorsal splint offers. Compare and buy dorsal splint products at the lowest prices. Comparison shopping made easy. Video sequence 1: dorsal intercalation in wild-type and die-1 embryos visualized ... is expressed at high levels in the C-derived posterior dorsal hypodermis. ... The word dorsal...

Buccal cavity

...ithin the oral cavity (i.e., sublingual, buccal , and local drug delivery) ... ... 1 - Structure of the buccal . cavity . InterFIG 2 - Dorsal intercalation of ... development of buccal cavity . InterFIG 6 - Arcade cells in tadpole. embryo ... Development - Buccal Cavity & Epithelium - M...

AP endonuclease

...... ... the ExoIII family AP endonucleases ... site might be recognized by the AP endonuclease (28,29) ... AP endonuclease through intercalation of the aromatic side ... In addition to its AP endonuclease activity, it exhibits other DNA repair ... In contrast, Nfo (an AP endonuclease...
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