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Insensitive in Medical News

Furious Reaction to insensitive Caption of the Picture of Abandoned Baby Girl

Several Australian feminists have denounced Telegraph, a popular daily, for carrying a large picture of an abandoned infant girl and a caption alongside , How could she? The all too obvious reference to the mother who abandoned the girl, for whatever reason, has infuriated many who say the...

HIV Positive Individuals Say Media Is Insensitive

People with HIV/AIDS in the Northeast say that the media is insensitive to the disease and hence social stigma is being attached to them// . "I have come across journalists refusing to shake hands, sat a few meters away from me, and didn't even look at my eyes during interview sessions. I al...

Variants of 'umami' taste receptor contribute to our individualized flavor worlds

...riminate the taste of weak L-glutamate from salt. Approximately 5% were unable to tell the two tastes apart, indicating that certain people are highly insensitive to umami and thus have difficulty detecting low levels of this taste quality. An additional 87 individuals were asked to assess the intensity of ...

Teen Stress May Have Roots in First Three Years of Life

... Overuse of day care, insensitive moms linked to higher stress levels in adolescence THURSDAY, Ma...young children who spent excessive time in child-care facilities or who had insensitive mothers may be more prone to stress in their teen years, a long-term study ...

Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report

...t the need of additional therapy," he says. However, about 5 percent of these patients experience rapidly progressing life-threatening disease that is insensitive to radioiodine and other treatment approaches. "Until only recently, we have not had any effective therapies for such patients." Pazopanib is an ...

Don't Let Your Summer Vacation Be Threatened by 'Guilty Vacation Syndrome'

...ks at the beach each year to refresh and rejuvenate," says Pete J., a GVS sufferer. "This year we've decided to cut back since we don't want to appear insensitive to the economic situation." Symptoms include misplaced emotions, indecisiveness and sadness. "People with 'Guilty Vacation Syndrome' must p...

Drug that targets vasculature growth attacks aggressive thyroid cancer

...t the need of additional therapy," he says. However, about 5 percent of these patients experience rapidly progressing life-threatening disease that is insensitive to radioiodine and other treatment approaches. "Until only recently, we have not had any effective therapies for such patients." Pazopanib is an ex...

Palliative care skills training needed for health-care staff in sub-Saharan Africa

...ymptoms and future care. Other patients talked about not receiving the results of blood tests, and described the trauma of being broken bad news in an insensitive manner. Carers reported not being told the patient's diagnosis directly, but learning it from his or her medical notes or from simply being sent on an...

Yale researchers discover mechanism for

...ically-developing two-year-olds perceived human motion in these moving points of light. They saw people," said Jones. "But children with autism were insensitive to the socially relevant cues in that motion, and they focused instead on physical cues that typically-developing children disregarded." Previous s...

Cell pathway on overdrive prevents cancer response to dietary restriction

...n insulin and IGF1 levels. Because the difference between the two groups was sensitivity or insensitivity to insulin and IGF1, Kalaany thought the insensitive tumors may have something amiss in a cellular process called the PI3K pathway, which is activated by insulin/IGF1. A search for mutations in two genes...
Insensitive in Medical Technology

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

...n the signal transduction protein S6K, while the other, TORC2, regulates cell survival through Akt. These complexes define the rapamycin-sensitive and insensitive branches of the PI3K/Akt/mTOR pathway. Inhibitors of TORC2 may have beneficial effects without toxicity to normal tissues since loss of TORC2 in gene...

Neurocrine Announces Top-Line Results From 702 Study (Lilac PETAL Study) of Elagolix for Treatment of Endometriosis Pain

... 250 mg (Week 12 value, p=0.068). Two of the exploratory scales (daily NRS and non-menstrual pelvic pain, each averaged monthly) were relatively insensitive to treatment effects. Although the daily pain scores improved numerically over the course of treatment on the primary endpoint NRS, the change from b...

Michael J. Fox Foundation Awards $2 Million for Research on Cognitive and Mood Symptoms of Parkinson's Disease

...itive Assessment (MoCA), for diagnosing Parkinson's-related cognitive changes. Currently available tests for detecting cognitive impairment are either insensitive to the specific changes that occur in Parkinson's, test only some of the brain functions that can be impaired in PD-related dementia, and/or can be hi...

BioNumerik Pharmaceuticals Observes Evidence of a Survival Increase in Lung Cancer Patients Participating in Tavocept(TM) Clinical Trial

...d survival observed in both the U.S. and Japan Tavocept trials appears to involve the novel pharmacological mechanisms of Tavocept, which appear to be insensitive to ethnicity or region. In addition, both trials showed a reduction in chemotherapy-induced toxicities in the Tavocept group with no dose limiting tox...

Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)

...idly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non- proliferating cells are relatively insensitive to Vidaza. Vidaza was approved in the U.S. for IV administration in January 2007. About Epigenetics Vidaza is the first of a new class of anti-can...

Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

...idly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non- proliferating cells are relatively insensitive to Vidaza. Vidaza was approved for IV administration in January 2007. About Epigenetic Therapy DNA methylation and histone deacetylation are the t...

Chroma Announces Positive Phase I Efficacy Data for Novel Cancer Therapy CHR-2797

...t cell growth or cause apoptosis (cell death) in a large number of cancer cell lines. Conversely, normal (non-tumour) cell lines have been shown to be insensitive to aminopeptidase inhibition. CHR-2797 is a potent inhibitor of aminopeptidases that has demonstrated strong preclinical efficacy as monotherapy and h...

MDS Patients on Five-Day Vidaza(R) Dosing Schedules Achieve Transfusion Independence Consistent with Seven-day Schedule

...idly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non- proliferating cells are relatively insensitive to Vidaza. Vidaza was approved for IV administration in January 2007. About Epigenetics Azacitidine is the first of a new class of anti-cancer com...

Instrumentation Laboratory Receives FDA Clearance for HemosIL RecombiPlasTin 2G Assay

...ecombinant tissue factor and a blend of synthetic phospholipids, which allow high sensitivity and lot-to-lot consistency. Additionally, the reagent is insensitive to the new antibiotic Cubicin (daptomycin for injection) and has an ISI value of approximately 1.0 on IL's ACL analyzers, traceable to WHO standards. ...

First Patient Enrolled in Europe in Ovature Phase III Ovarian Cancer Trial

...tcome of this multi-centre study will be a significant medical advance for thousands of women with late stage ovarian cancer whose tumours have become insensitive to the existing chemotherapeutic drugs," Professor Vergote said. "As one of Europe's largest cancer institutions, it is important for us to be a part...
Insensitive in Medical Products

CoaguChek XS

Features:...ed during the measuring process (e.g. check for sufficient blood volume application). Automatic control of internal system functions. Reagent is insensitive to heparin, allowing continuous vitamin K antagonist (VKA) therapy management, e.g. during transition from heparin to VKA therapy. Better clinical ...
Company:Roche Diagnostics

Soft Line Silicone Foot Orthotics

Features:...e relief Soft line silicone construction and dynamic adaptation to the feet for greater patient comfort Silicone products have skin tolerance, are insensitive to perspiration, easily washable and fit into any athletic, dress or walking shoe ...
Company:Bird & Cronin Inc.
Insensitive in Medical Dictionary

Papule

...n. , pl. -ules also -ulae ( ). A small, solid, usually inflammatory elevation of the skin that does not contain pus chancre n. A dull red, hard, insensitive lesion that is the first manifestation of ... This single red papule (bump), usually occurring about three weeks after ... Online Medical Di...

Endocrine

...experienced ... Advanced Parathyroid Endocrine Surgical Procedures - Video Education ... WASHINGTON -- Breast cancer that has become hormone insensitive may revert to sensitive status with targeted therapy, investigators reported here. Describes Graves' disease, an autoimmune disorder and the most ...

Chancre

...to Treponema pallidum, the gram-negative spirochaete bacterium yielding syphilis. Chancres transmit the sexually... chancre n. A dull red, hard, insensitive lesion that is the first manifestation of syphilis. ... A chancre is a painless ulceration formed during the primary ... chancre a sma...

Anesthetic

.... ... Anesthetic drugs that have exceeded their ... anesthetic also anaesthetic adj. Relating to or resembling anesthesia. Causing anesthesia. insensitive ... the aid of an anesthetic , people can undergo surgery ... anesthesia also anaesthesia n. Total or partial loss of sensation, especially ....

Anesthesia

...ergo surgery and other procedures without the distress and pain they would... Local anesthesia is any technique to render part of the body insensitive to pain ... Surface anesthesia - application of local anesthetic spray, solution or cream to ... Anesthesia , absence of physical sensati...
Insensitive in Biological News

Bright lights, not-so-big pupils

...ctrical current generated by one cell. They found that these cells are very insensitive to light, in contrast to rods, which are very sensitive and therefore enabl... for our vision in daylight. "The next question was, What makes them so insensitive to light? Perhaps each photon they capture elicits a tiny electrical signal...

Researchers find chink in the armor of viral 'tummy bug'

...y, 3D modelling and cell-based assays to observe the interaction between the virus and host cells. "We found that a human strain previously through insensitive to sialidase does in fact recognise and bind to sialic acid, but it is a sialic acid not accessible to sialidase treatment." Professor von Itzstein sa...

Brain enzyme may play key role in controlling appetite and weight gain

...ct against the natural tendency of mammals on a high-fat diet to overeat. People deal with all those calories by putting on extra weight and becoming insensitive to insulin two of the hallmarks of metabolic syndrome, a group of risk factors that raise the risk of heart disease and type 2 diabetes. When anim...

Early parenting plays key role in infants' physiological response to stress

...tive now showed the expected cardiac response while they were exposed to the stressful situation. Those infants with the risk form of the gene who had insensitive mothers continued to show the ineffective cardiac response to the stressor. These findings suggest that although genes play a role in the development ...

Scientists develop new method to investigate origin of life

... The conventional method for estimating evolutionary relationships, called multiple sequence alignment, also produces evolutionary trees, but can be insensitive to relationships among the most distantly related proteins, in large part because it makes only one simultaneous comparison across all of the genetic/...

Why a common treatment for prostate cancer ultimately fails

...ir grows. When it's very active on the top of the skull, toward the front, hair falls out and men become bald. And the hair on the back of the head is insensitive to the receptor. The effects of hormones depend on the location. "We found that the same is true within the cells of the prostate itself," said Cha...

UCLA researchers locate and image prostate cancer as it spreads to lymph nodes

... Currently, physicians don't know if a treatment is attacking cancer cells until, using traditional imaging, they see a decrease in tumor size, an insensitive approach that can take weeks and months. And if the treatment isn't working, the patient is exposed to a toxic therapy that isn't helping them. If Wu ...

A new idea for how anti-aging products delay ripening of fruit and wilting of flowers

... 1-MCP works by beating ethylene to the receptors. By binding with a sufficient number of receptors chemically and permanently, it forever makes them insensitive to ethylene. The plants do not perceive ethylene thereafter, preventing ripening and wilting. Furthermore, unlike ethylene, 1-MCP does not inacti...

Eliminating germline lengthens fly lifespan, Brown study shows

...r than typical flies results that matched Kenyons finding in worms. Flatt and Tatar speculated that these flies might live longer because they are insensitive to the effects of insulin. Past research at Brown, and other universities, shows that when animals such as flies, worms and mice live longer when they...

NC State researchers identify genes key to hormone production in plants

...out more about how auxin production is triggered, the NC State team identified a mutant strain of Arabidopsis or mustard weed that had a root system insensitive to the growth inhibitory effect of ethylene. When the team looked at the genome of this mutant strain of mustard weed, they discovered that its l...
Insensitive in Biological Technology

Brooks Instrument's New Mass Flow Controller Series Is Immune to Pressure and Temperature Fluctuations

... flow controller, a totally new family of mass flow products designed to be insensitive to fluctuations in pressure and temperature. Built on a standard 1.125-inch...flow controller , a totally new family of mass flow products designed to be insensitive to fluctuations in pressure and temperature. Built on a standard 1.125-inch...

MammaPrint(R) Breast Cancer Test Provides Valuable Insight for Personalized Treatment Decisions

...cancer recurrence with MammaPrint, 31% (20 of 64) were predicted to be highly sensitive to endocrine therapy while 88% (56 of 64) were predicted to be insensitive to chemotherapy. The remaining 134 patients who were considered to be at high risk for cancer recurrence, were predominantly predicted chemo-sensitive...

Sticky gecko feet: The role of temperature and humidity

...paratively poorly and the humidity level is less important. Previous work by other labs using isolated setae suggested that clinging ability should be insensitive to variation in both temperature and humidity. Our work with live geckos indicates a need to further explore the role of temperature and humidity on a...

EMEA Accepts for Review Vidaza(R) Marketing Authorization Application for Higher-Risk Myelodysplastic Syndromes

...idly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non- proliferating cells are relatively insensitive to Vidaza. Vidaza was approved for IV administration in January 2007. About Epigenetics Vidaza is the first of a new class of anti-cancer compound...

Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes

...pidly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non-proliferating cells are relatively insensitive to Vidaza. Important Safety Information Vidaza is contraindicated in patients with a known hypersensitivity to azacitidine or mannitol and in patien...

Geezers, grungers, gen-Xers and geeks - a look at workplace generational conflict

... your workplace. Is there a dominant view at work in your organization that is shaped by one generation of workers? Is that dominant generational view insensitive toward the perspectives of individuals from different generations? Our survey showed that the more experienced the workers, the less aware they were o...

BarCamp talk turns to Internet dating

...nce" for Wisconsin technology professionals, Huber provided advice about maximizing efficiency and minimizing hurt feelings in the sometimes gawky and insensitive world of online romance., which includes popular dating sites like eHarmony.com and Match.com . At BarCamp, there was little conversation about ...

Calcium Flux Assays using the LabChip 3000

... dye, the cells are suspended and washed to remove unincorporated dye. It is not critical to wash cells extensively as the LabChip assay is relatively insensitive to background fluorescence. Suspensions of adherent cell lines can be formed by a variety of methods such as trypsinizing or EDTA treatment. After lif...

DNA Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #37)

...despread popularity in the microplateformat. 1 However, A 260 measurements do not distinguish between dsDNA,ssDNA and RNA. Also, they are relatively insensitive (limit of quantitationapproximately 250 ng/mL in traditional spectrophotometers 2,3 and approximately 100 ng/well in a 96-well microplate 1 ). Below ...

UV Absorbance Measurements in SpectraMax Microplate Spectrophotometers MaxLine Application Note #32)

...oratories. Dust particles have not been a serious problem in the past because microplate readers had large optical beams and therefore were relatively insensitive to occasional particles in the light path. Modern microplate spectrophotometers, however, have optics designed for microplates with smaller wells and ...
Insensitive in Biological Products

pHyPer-dMito from Evrogen JSC

Description:...erted into the regulatory domain of Escherichia coli protein OxyR (OxyR-RD), HyPer demonstrates submicromolar affinity to H2O2 and at the same time is insensitive to other oxidants. HyPer does not cause artifactual ROS generation and can be used for detection of fast changes of H2O2 concentration in different ce...
Company:Evrogen JSC
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