Bayer and Onyx Initiate Phase 3 Trial of Nexavar in Non-Small Cell Lung Cancer
WAYNE, N.J. and EMERYVILLE, Calif., June 1 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced that the companies have begun enrolling patients in an international Phase 3 trial to evaluate Nexavar(R) (sorafenib) tablets...
Low Vitamin D Levels May Initiate Cancer Development
Study suggests loss of communication among cells tied to this nutritional deficit
FRIDAY, May 22 (HealthDay News) -- Low levels of vitamin D may contribute to cancer development, U.S. researchers have found.
"The first event in cancer is loss of communication among cells due to, am...
Aethlon Medical Announces Engagement of RedChip Companies to Initiate Investor and Media Relations Programs
SAN DIEGO, April 21 /PRNewswire-FirstCall/ -- Aethlon Medical, Inc. (OTC Bulletin Board: AEMD), developer of the Hemopurifier(R), a first-in-class medical device to treat infectious disease, today announced that it has hired RedChip Companies, Inc. to lead its investor relations outreach pr...
Medivation Receives FDA Permission to Initiate Phase 3 Trial of MDV3100 in Castration-Resistant Prostate Cancer
SAN FRANCISCO, March 18 /PRNewswire-FirstCall/ -- Medivation, Inc. (Nasdaq: MDVN ) today announced that it has received written permission from the U.S. Food and Drug Administration (FDA) to begin a pivotal Phase 3 trial of MDV3100, its novel androgen receptor antagonist, in patients with metast...
Cardiologists initiate STILETTO study to investigate treatment options for women with chest pain
CHICAGO Women who experience chest pain are sent to a cardiologist to go through a standard battery of tests, and often times test results show no evidence of coronary artery disease which is the most common cause of chest pain. This is a less common occurrence in men, and these women are sent ho...
Eisai Will Initiate First Head-to-Head Study Comparing Dacogen(R) (decitabine for injection) and Vidaza(R) (azacitidine) in Patients with Myelodysplastic Syndromes
Randomized Comparator Study to Evaluate Efficacy of Commercially Available Hypomethylating Agents
WOODCLIFF LAKE, N.J., Dec. 2 /PRNewswire/ -- Eisai Corporation of North America today announced that it plans to initiate
the first clinical trial evaluating the activity of Dacogen(R) (deci...
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Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
Start of trial triggers $10 million milestone payment to Pharmasset
PRINCETON, N.J., April 24 /PRNewswire-FirstCall/ -- Pharmasset, Inc. (Nasdaq: VRUS ) and Roche (Roche SWX: RO, ROG; Pink Sheets: RHHBY) today announced that the first patient has been dosed in a Phase IIb study of R7128, th...
Pfizer and Medivation Initiate Phase 3 Trial of Dimebon Added to Donepezil in Patients with Alzheimer's Disease
--New 12-month study broadens Phase 3 clinical program to further evaluate the benefits of Dimebon in Alzheimer's Disease--
NEW YORK and SAN FRANCISCO, April 15 /PRNewswire-FirstCall/ -- Pfizer (NYSE: PFE ) and Medivation, Inc. (Nasdaq: MDVN ) today announced the initiation of a 12-mont...
American Oriental Bioengineering to Initiate a Phase One Clinical Trial in the United States of AOBO-001 Oral Capsule
NEW YORK, March 9 /PRNewswire-Asia-FirstCall/ -- American Oriental
Bioengineering, Inc. (NYSE: AOB ), a China-based pharmaceutical company
dedicated to improving health through the development, manufacture and
commercialization of a broad range of prescription and over the counter ("OTC")
TissueGene Announces Regulatory Allowance to Initiate Phase IIa Study of TG-C in South Korea for Osteoarthritis of the Knee
ROCKVILLE, Md., March 2 /PRNewswire/ -- TissueGene, Inc. announced today that its South Korean licensing partner Kolon Life Science, Inc. (KLS) has received regulatory allowance from the Korea Food and Drug Administration (KFDA) to initiate
a Phase IIa clinical trial of TissueGene-C (TG-C) in pati...
Abbott and Enanta Initiate Phase 1 Clinical Trial on ABT-450 HCV Protease Inhibitor
ABBOTT PARK, Ill., and WATERTOWN, Mass., Feb. 18 /PRNewswire-FirstCall/ --
Abbott ( NYSE: ABT ) and Enanta Pharmaceuticals announced today the advancement
of their Hepatitis C (HCV) collaboration with a first-in-human study
evaluating ABT-450, an oral protease inhibitor for the treatment of ...
ImQuest Submits Investigational New Product Application to the Food and Drug Administration to Initiate HIV Therapeutic Clinical Trials with IQP-0410
FREDERICK, Md., Jan. 7 /PRNewswire/ -- ImQuest Life Sciences announced today the successful submission of an IND application to the Food and Drug Administration to initiate
human clinical trials for their lead pyrimidinedione HIV inhibitor IQP-0410. ImQuest anticipates initiating their Phase 1 stu...
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Schwartz Principles of Surgery
Description:...m-designed user interface, Schwartz Principles of Surgery, PDA Edition enables you quick access to the answers you need to make the right diagnosis or initiate
Rhein Tubular Capsulorrhexis Forceps
Description:... 1-Millimeter Incision.
Special Curved Shaft Provides A More Comfortable Approach To The Incision.
Cystotome Tips Are Used To Pinch The Capsule To initiate
And Complete A Circular Tear.
Titanium Handle Is Lighter In Weight For Improved Ergonomic Feel. Ideal For Bi-Manual Phaco Micro-Surgery.
Company:Rhein Medical, Inc.
Acuity® Central Station
Description:... from a single computer workstation. The clinician interface uses simple point and click actions with a computer mouse or trackball. The clinician can initiate
or change monitoring functions from either the Acuity Central Station or the bedside monitor....
Company:Welch Allyn Medical Products
VNS Therapy System
Description:... nerve, which then sends signals to the brain. Each device is programmed for the individual patient, and the patient or a caregiver has the ability to initiate
or abort stimulation with the use of a hand-held magnet....
Features:...eration in the WMTS band Distributed antenna system Choice of 3- and 5-lead ECG or EASI derived 12-lead ECG Configurable button that can be used to initiate
waveform strips or a STAT SpO2 measurement User-defined SpO2 measurement intervals Ability to forward alarms to pagers, marquees, or other wireless ...
Company:Philips Medical Systems
Radianse Indoor Positioning Context-sensitive Medicine
Features:...fied period of time, the Radianse IPS recognizes this context as "Patient transfer", sending a message to a hospital or clinical information system to initiate
the transfer. ...
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... Non-profit foundation providing reliable, scientifically accurate, personalized ... Thus, research is showing that vitamin K not only helps to initiate
blood ... and Vitamin K . The food you eat can affect how your medicine works. ... Do you want to know more about vitamin K ? ... Watch ...
...me diseases by vaccination . ... Why do puppies and kittens require a series of vaccinations ? ... Immunizations ( vaccinations ) are given to initiate
or augment resistance to an ... Vaccinations against the following disorders are also recommended routinely for ... Immunizations . Alternati...
...ct thyroxine levels. Thyroxine contains iodine. ... A Practical Approach to the Treatment of Subclinical Hypothyroidism at ... Many clinicians initiate
thyroxine replacement therapy for all patients with TSH ... Thyroxine , as noted above, affects most tissues, but there is usually a ... It has...
...gnant potential, has experienced a ... Hypoxia in the intestinal mucosa causes oxidative and nitrosative stress, but ... the mucosa , and might initiate
the cascade of events leading to hyperdynamic ... ... whites • sodium channels • amiloride • nasal mucosa • membrane potentials ... was then...
...eat items like the Lipid Complex. (PUFAs) that are substrates of lipid peroxidation that may lead to loss of the ... In particular, they can initiate
lipid peroxidation ... surfactant protein a.pdf'> Lipid peroxidation of membrane polyunsaturated fatty acids by reactive oxygen ... Conj...
Graft Versus Host Disease
...re transplantation, rid ... graft - versus - host disease n. A pathological condition in which cells from the transplanted tissue of a donor initiate
an immunologic attack on the Overview: Barnes and Loutit first described (in mice) what is now known as graft versus host disease (GVHD)...
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Biologists visualize protein interaction that may initiate viral infection
Biologists at Purdue University have taken a "snapshot" of a Velcro-like protein on a cell's surface just after it attached to the dengue virus, a linkup thought to initiate
the early stages of infection.
The virus, which is spread by mosquitoes, infects more than 50 million people annually, kill...
Carnegie donates landmark clones to biology
...ence Foundation funding, researchers at the Carnegie Institution's Department of Plant Biology have cloned genes to produce membrane proteins that may initiate
the instructions for genes to turn on in the nucleus. They just donated 2010 of the clones for genes that function in the cell's interaction with its ...
Plankton Power and RTDC announce proposed algae-to-biofuels pilot facility on Cape Cod
...rch. The use of algae as a fuel has major potential and can be nurtured right on Cape Cod."
Beginning in autumn 2010, Plankton Power expects to initiate
pilot-scale operations to generate up to one million gallons of biodiesel per yearenough fuel to supply Cape Cod's current biodiesel usage. The compan...
Protecting cells from their neighbors
...y in the advanced online edition of EMBO Reports .
In the first hours of embryonic life, the egg cells show intense gene transcription activity to initiate
development, with the exception of germ cells which are totally inert and repressed. The DNA of the "sex" cells will pass from parents to offspring, a...
Discovery to aid in future treatments of third-world parasites
...briele Schramm of the Research Centre Borstel in Germany had previously shown that a protein called alpha-1 can support Th2 responses but is unable to initiate
However, new findings from an international study between Mohrs, Schramm, and Maria Yazdanbaksh of the Leiden University Medical Center in th...
The value of variation: Ecologists consider the causes and consequences
...involving both biologists and mathematicians to studying the issue.
"By establishing connections between these usually separate fields, we hope to initiate
a new field of mathematical ecology that melds genetics, evolution, and dynamic foraging behavior into ecological models that will determine how intra...
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Orcrist Bio Inc. Receives Approval from European Competent Authority to Initiate its Planned Phase I, Open-label, Single-ascending-dose, Safety Study of HYC750
CALGARY, April 6 /PRNewswire/ - Orcrist Bio Inc. (ORC) a biotechnology company developing stem cell-mobilizing pharmaceuticals, announced today the approval of its Phase I, open-label, single-ascending-dose, safety study of HYC750 in healthy male volunteers, by the European Competent Authority in ...
Helix BioPharma Receives Approval to Initiate Phase II Pharmacokinetic Clinical Study of Topical Interferon Alpha-2b in Patients with Low-Grade Cervical Lesions
AURORA, Ontario, March 16 /PRNewswire/ -- Helix BioPharma Corp. (TSX, FSE: "HBP") announced that it has received the necessary regulatory approvals in Germany to initiate
its planned Phase II pharmacokinetic study of Topical Interferon Alpha-2b in patients with low-grade cervical lesions.
YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER
MISSISSAUGA, ON, Jan. 5 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Alternext US:YMI, TSX:YM, AIM:YMBA), an oncology company that identifies, develops and commercializes differentiated products for patients worldwide, today announced that it has received clearance from Canadian regulatory a...
Virginia Tech engineers identify conditions that initiate erosion
Blacksburg, Va. -- Wind, water, and waves erode billions of tons of soil from the earth's surface. As a result, many rivers are plagued with excessive amounts of suspended sediment. According to the U.S. Environmental Protection Agency, such eroded sediment is the largest nonpoint source pollution...
DermTech and Rady Children's Hospital-San Diego, Initiate Study to Understand Effects of Vitamin D as a Treatment for Atopic Dermatitis in Children and Young Adults
DermTech's Non-invasive EGIR Technology to be Employed to Generate Genetic, Objective Data on Therapy Response
LA JOLLA, Calif., Oct 27 /PRNewswire/ -- DermTech, a biotechnology
company developing EGIR(TM) (Epidermal Genetic Information Retrieval)
technology for the non-invasiv...
Neogen Honored by Forbes; Two Brokerage Firms Initiate Coverage
LANSING, Mich., Oct. 15 /PRNewswire-FirstCall/ -- Forbes Magazine has
named Neogen Corporation (Nasdaq: NEOG ) to its annual list of the 200 Best
Small Companies in America for the fourth consecutive year and seventh time
in the last nine years.
"Conventional wisdom would have investors fle...
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ARCA (Anti Reverse Cap Analog) from Ambion
Description:...RCA) is a modified cap analog in which the 3 OH group (closer to m7G) is replaced with OCH3. Because of this substitution, the RNA polymerase can only initiate
transcription with the remaining hydroxyl group thus forcing ARCA incorporation in the forward orientation. As a result, unlike transcripts synthesize...
Cell Invasion Colorimetric Assay Kit from CHEMICON
Description:... Invasion through the extracellular matrix (ECM) is an important step in tumor metastasis. Cancer cells initiate
invasion by adhering to and spreading along the blood vessel wall. Proteolytic enzymes, such as MMP collagenases, dissolve tiny holes in the sheath-l...
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... The activation energy in chemistry is the energy needed by a system to initiate
a particular process. Activation energy is often used to denote the minimum energy needed for a specific chemical reaction to occur. For a reaction ...
...an organism's life cycle. For example, the differentiation of human fingers in the developing embryo requires the cells in between the fingers to initiate
apoptosis so that the fingers can separate. As will be explained further on, the way the apoptotic process is executed facilitates the safe disposal o...
...ing genes, which together form pili on the cell surface, polymeric proteins that can attach themselves to the surface of F-negative bacteria and initiate
the mating. The pili themselves do not seem to be the structures through which the actual exchange of DNA takes place; rather, some proteins coded in ...
... The distinction between plasmids and chromosomes is poorly defined, though size and necessity are generally taken into account. Bacterial chromosomes initiate
replication and one origin of replication.
Two types of chromatin can be distinguished:
Euchromatin , which consists of DNA ...
...hin the cytoplasm or the nucleoplasm . The hormone has to pass through the plasma membrane, usually by passive diffusion, to reach the receptor and initiate
the signal cascade . The nuclear receptors are ligand -activated transcription activators; on binding with the ligand (the hormone), they will pas...
...ves synaptic "inputs" from many others. When action potentials "fire" simultaneously in several neurons that weakly synapse on a single cell, they may initiate
an impulse in that cell even though the synapses are weak. On the other hand, a pre-synaptic neuron releasing an inhibitory neurotransmitter such as ...
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...re... Salivary glands produce the saliva used to moisten your mouth, initiate
... You may have a secondary infection of salivary glands from nearby ...m ... Salivary glands produce the saliva used to moisten your mouth, initiate
... Secondary infection of salivary glands from adjacent lymph nodes ...
...d through... In addition, plastid metabolism is responsible for generating economically ... A number of plastid types have also been shown to initiate
protrusions from the ... Plastid genes in higher plants are transcribed by two distinct RNA polymerases: ... plants a small family of nuclear g...
...e cells (Fig. 3B), and these primordia emerged ... proximity to lateral roots that emerged from the pericycle tissue ... Lateral roots initiate
from internal cells of the pericycle . ... A small group of pericycle cells reorient their axis of polarity to the radial ... A. epidermi...
...ment, organogenesis is the process by which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. Internal organs initiate
development in humans within the 3rd to 8th weeks in... organogenesis n. , pl. -ses ( ). The formation and development of the organs of living th...
...n a single neuron would serve no purpose ... that travel from one neuron to the other to regenerate the nerve impulse . ... ... which do not initiate
the nerve impulse are called "submiminal. ... may ultimately cause the discharge of a nerve impulse . ... Nerve Impulse ... Nerve cel...
...monas ... amplification of Phytomonas minicircles . ... Mitochondrial minicircles contain the genes for guide ... Here, the free minicircles initiate
unidirectional theta structure replication. ... When all the minicircles have been replicated and reattached, the final gaps are ... Replication ...