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inhibits in Medical News

JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab

A novel anticancer agent, consisting of a monoclonal antibody linked to a chemotherapy drug, showed substantial antitumor activity in ovarian cancer cell lines and in mice, according to a study published online July 29 in the Journal of the National Cancer Institute . The agent, known as an im...

Survey Finds 64% of Americans Unaware Sunscreen Inhibits Vitamin D Production

FERNDALE, Wash., July 28 /PRNewswire/ -- Nearly 64 percent of Americans surveyed are unaware sunscreen hinders the body's ability to produce vitamin D - a nutrient found to support the immune system, bone strength, colon health and more.* The survey was conducted by WELLESSE...

Drug inhibits neuroblastoma blood supply in pre-clinical tests

SAN DIEGO - Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a way to prevent blood vessels from aiding the growth of neuroblastoma, a childhood cancer. The pre-clinical study was presented today in a platform session at the 22nd an...

Researchers find drug that inhibits acute leukemia cell growth

SAN DIEGO - Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered how to turn off a certain receptor that promotes the growth of leukemia cells. The pre-clinical study was presented today in a platform session at the 22nd annual mee...

Progen Technology Switches on Cancer Fighting Genes and Inhibits Tumor Growth

BRISBANE, Australia, April 20 /PRNewswire-FirstCall/ --Progen Pharmaceuticals Limited (ASX: PGL; Nasdaq: PGLA ) has released data that shows its epigenetic technology successfully inhibits tumor growth. The results of the pre-clinical experiments, presented by Progen's collaborators at the ...

Drug Inhibits Colon Cancer in Mice

Treated with enzastaurin, even tumors that did develop weren't as advanced, study finds THURSDAY, Feb. 12 (HealthDay News) -- A drug called enzastaurin significantly reduced the development of colon cancer in mice, and tumors that did develop were less advanced and aggressive than thos...

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inhibits in Medical Technology

Portola Announces Data Showing Its Anti-Platelet Drug Inhibits Platelets in Clopidogrel (Plavix(R)) Non-Responders

- Direct-Acting PRT060128 Provides Reversible, High-level Platelet Inhibition with Immediate Onset of Action - NEW ORLEANS and SOUTH SAN FRANCISCO, Calif., Nov. 12 /PRNewswire/ -- Portola Pharmaceuticals, a biopharmaceutical company developing innovative drugs that provide sign...

SuperGen's JAK2 Inhibitor, SGI-1252, Inhibits in Vivo Tumor Cell Proliferation

DUBLIN, Calif., June 16 /PRNewswire-FirstCall/ -- SuperGen Inc. (Nasdaq: SUPG ), a pharmaceutical company dedicated to the discovery, rapid development and commercialization of therapies for solid tumors and hematological malignancies, today announced at the 13th Congress of the European Hema...

New Study Demonstrates ACTEMRA(R) (tocilizumab) Inhibits Progression of Joint Damage in Rheumatoid Arthritis Patients

- Fifth International Phase III Study Shows Positive Results with X-ray Data - NUTLEY, N.J., May 9 /PRNewswire/ -- Roche today announced one-year results from a new two-year Phase III study showing that ACTEMRA(TM) (tocilizumab) can significantly inhibit progres...

Addition of INTEGRILIN(R) (Eptifibatide) to Bivalirudin Plus Standard of Care Inhibits Platelet Aggregation in Patients Undergoing Elective Coronary Stenting

ORLANDO, Fla., Nov. 5 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) and The Sinai Center for Thrombosis Research at Sinai Hospital of Baltimore today announced results of the recently completed CLEAR PLATELETS 2 (Clopidogrel Loading with Eptifibatide to Arrest the Reactiv...

Preclinical Data Show Alfacell's Onconase Inhibits Tumor Growth of Non-Small Cell Lung Cancer, Breast Cancer Cells

Poster Presented at AACR Annual Meeting BLOOMFIELD, N.J., April 16, 2007 /PRNewswire-FirstCall/ -- Alfacell Corporation today announced that in vivo and in vitro preclinical data presented in a poster at the American Association for Cancer Research (AACR) Annual Meeting show that ONCONASE (ranpirn...

Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome

...There remains a need for effective, well tolerated therapies for MDS having novel mechanisms of action. TELINTRA has a novel mechanism of action that inhibits a target enzyme called glutathione S- transferase P1-1 which in turn facilitates the activation of JNK kinase, a key regulator of cellular growth and ...
inhibits in Medical Products

Free Testosterone RIA Test

Description:...ity [1], while the remainder is loosely bound to albumin. Both the albumin-bound and free fractions may be biologically active, while SHBG effectively inhibits testosterone action. Measurement of the free or unbound fraction of serum testosterone has been proposed as a means of estimating the physiologically ...
Company:Diagnostic Systems Laboratories, Inc.

Growth Hormone Binding Protein ELISA Test

Description:...n plasma in nanomolar concentrations, sufficient to complex approximately 50% of plasma GH. GHBP modulates GH action via a variety of mechanisms. It inhibits GH action by competing with the GH receptor for ligand and by generating unproductive heterodimers with the GH receptor at the cell surface, as oppose...
Company:Diagnostic Systems Laboratories, Inc.

Free Testosterone EIA Test

Description:...ity [1], while the remainder is loosely bound to albumin. Both the albumin-bound and free fractions may be biologically active, while SHBG effectively inhibits testosterone action. Measurement of the free or unbound fraction of serum testosterone has been proposed as a means of estimating the physiologically ...
Company:Diagnostic Systems Laboratories, Inc.

Penicillin-Streptomycin

Description:... Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the aminoglycoside antibiotics and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin i...
Company:Roche Applied Science

Gentamicin Sulfate

Description:...5 to 5.5 Loss on drying: Residue on Ignition: Gentamycins content: C 1 : 25-50% C 2 + C 2a : 25-55% C 1a : 10-35% Mode of Action: Bactericidal, inhibits normal protein synthesis. Applications: Very stable Autoclavable Requires no refrigeration Effective when combined with an antibiotic ...
Company:USB Corporation

Gentamicin Sulphate

Description:... Gentamicin Sulphate : Antibiotic that inhibits normal protein synthesis. USBio analysed. Autoclavable....
Company:Amersham Biosciences (A Division of GE Healthcare)
inhibits in Medical Dictionary

Yeast

...living, microscopic, single-cell organism that, as it grows, converts ... Active dry yeast is in the form of tiny, dehydrated granules. ... Salt inhibits the growth of yeast . Learn about the different types of yeast , plus how to use and store it. ... Yeast also thrives on starch, which it converts...

Vasodilation

...on ... BK promotes vasodilation ,1 exerts antiproliferative effects,2 inhibits thrombin ... Although BK is known to cause vasodilation through the B2 re...w complete and up to date Fentanyl Citrate ... peripheral vasodilation ; inhibits intestinal peristalsis and sphincter of Oddi ... This vasodilation...

Haptoglobin

...ans is encoded by the HP gene. In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The... Haptoglobin is a protein produced by the liver. ... When the haptoglobin and hemoglobin attach, the new mol...

Disinfectant

...er complete and full sterilisation, without ... disinfectant n. An agent, such as heat, radiation, or a chemical, that destroys, neutralizes, or inhibits the growth of disease-carrying potassium permanganate n. A dark purple crystalline compound, KMnO 4 , used as an oxidizing agent and disinfectant...

Digoxin

...ing digoxin , tell your doctor ... Accurate, FDA approved Digoxin information for healthcare professionals and patients - brought ... Digoxin inhibits sodium-potassium ATPase, an enzyme that ... Specifies the medication digoxin (Lanoxin), a drug used to treat congestive ... Digoxin also s...

Contraction

....com. Thousands of Brands. Hundreds of Stores. Calcium cycling/excitation- contraction coupling. Heart failure - basic studies ... FABP4 Acutely inhibits Cardiomyocyte Contraction ... A contraction stress test checks to see if your baby (fetus) will be okay with the reduced oxygen levels tha...
inhibits in Biological News

Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?

This release is available in Chinese . Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by ca...

Herpes drug inhibits HIV in patients infected with both viruses

This release is available in French . Researchers at the U.S. National Institutes of Health (NIH), McGill University and other institutions have discovered how a simple antiviral drug developed decades ago suppresses HIV in patients who are also infected with herpes. Their study was publi...

A compound extracted from olives inhibits cancer cells growth and prevents their appearance

A research group of the University of Granada has found out that maslinic acid, a compound present in the leaf and the olive skin wax extracted from alpeorujo (crushed olive pulp), has the capacity of preventing cancer as well as regulating apoptosis in carcinogenic processes. Maslinic acid is ...

Multiple malaria infection inhibits spread of parasite

People who are frequently infected with malaria parasites can develop immunity against the gametocyte, the infectious stage. This immunity inhibits the spread of the parasite. Dutch researcher Mike van der Kolk discovered this during his research into malaria transmission under the inhabitants of C...

Antibiotic inhibits cancer gene activity

A little-known antibiotic shows early promise as an anti-cancer agent, inhibiting a gene found at higher-than-normal levels in most human tumors, according to researchers at the University of Illinois at Chicago College of Medicine. Their findings appear in the Oct. 1 issue of Cancer Research. ...

Gene therapy inhibits epilepsy in animals

For the first time, researchers have inhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signaling pathways in the brain, neurology researchers found that they could significantly reduce the development of epileptic seizures in rats. "We have sh...

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inhibits in Biological Technology

Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice

San Diego-Based Carolus Therapeutics Focuses on Discovery and Development of Anti-Inflammatory Drugs Based on Collaborators' Findings at RWTH Aachen University in Germany SAN DIEGO, Jan. 5 /PRNewswire/ -- Research published in Nature Medicine shows that the disruption of the interactions be...

ARIUS presents new findings showing therapeutic antibody inhibits human leukemic cancer stem cells

- Data on ARIUS' novel CD9 therapeutic antibody to be presented at AACR Special Conference on Cancer Stem Cells - TORONTO, Feb. 13 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX: ARI), a biotechnology company discovering and developing the next wave of antibody therapeutics, ...

QSB Anti-Virulence Platform Inhibits Biofilm Formation by Staphylococcus Aureus MRSA and Candida sp

MELBOURNE, Florida, February 7 /PRNewswire/ -- QuoNova LLC, which is 88.7% owned by XL TechGroup, Inc. (AIM: XLT), has generated preliminary in-vitro data indicating high efficacy of selected Quorum Sensing Blockers ("QSB") in inhibiting biofilm formation by MRSA (methicillin-resistant Staphyl...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

...t advances through the clinic." These data are published in the August 7, 2009 edition of Cell Stem Cell in an article titled "DLL4 Blockade inhibits Tumor Growth and Reduces Tumor Initiating Cell Frequency." The authors of the article include Dr. Michael Clarke of Stanford University, Dr. Hoey and...

Keryx Biopharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results

...atients with end-stage renal disease. Keryx is also developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 ...

Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Second Quarter 2009 Financial Results on Thursday, August 6, 2009 at 8:30am EDT

...atients with end-stage renal disease. Keryx is also developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 ...
inhibits in Biological Products

Anti-Factor XII Light Chain Monoclonal Antibody, Unconjugated from QED Bioscience Inc.

Description:... This monoclonal antibody recognizes the light chain of human Factor XII and at 100 nM inhibits 50% of Factor XII activity. It may be used in ELISA to detect human Factor XII and in coagulation assays. Product Category: Coagulation Factor Antibo...
Company:QED Bioscience Inc.

Anti-Acetylcholine Receptor-alpha (AChR-alpha) Monoclonal Antibody, Unconjugated from CHEMICON

Description:... Human acetylcholine receptor (AChR)-alpha. Exhibits homogenous, high affinity binding to the receptor. Binds weakly to a64-78. inhibits binding of many myasthenia gravis sera to human AChR....
Company:CHEMICON

Rosmarinic acid from Biotrend Chemikalien GmbH

Description:... Antiinflammatory, cytostatic and anti-viral agent. inhibits several important steps of angiogenesis including proliferation, migration, adhesion and tube formation of HUVEC cells. Also reduces intracellular rea...
Company:Biotrend Chemikalien GmbH

Curcumin (technical grade) from Cayman Chemical

Description:... Curcumin is an extract of turmeric root with antioxidant, anti-tumor promoter, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages....
Company:Cayman Chemical

Anisomycin from Sigma-Aldrich

Description:... Antibiotic isolated fromStreptomyces griseolusthat inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in euka...ted protein (MAP) kinases (JNK/SAPK and p38/RK). Antiprotozoal agent.• inhibits formation of the 80S ribosomal complex from 60S subunits• From Strept...
Company:Sigma-Aldrich

Puromycin, Dihydrochloride from Calbiochem

Description:...p- methoxyhydrocinnamamido)-3′-deoxy-N,N-dimethyladenosine, 2HCl White to off-white solid. PROTECT FROM MOISTURE. Protein synthesis inhibitor. inhibits translation by causing premature release of nascent polypeptide chains. Induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells. Pu...
Company:Calbiochem
inhibits in Biological Definition

Cell growth

...ally phosphorylates the Cdc2 cell cycle regulatory protein on a tyrosine residue. This covalent modification of the molecular structure of Cdc2 inhibits the enzymatic activity of Cdc2 and prevents cell division. In Wee1 mutants, there is less Wee1 activity and Cdc2 becomes active in smaller cells, caus...

Colchicine

...ahydro-1,2,3,10-tetramethoxy-9-oxobenzo[ a ]heptalen-7-yl)acetamide] . It inhibits the cytoskeleton by binding to tubulin , one of the main constituents of...ing mitosis , a process heavily dependent on cytoskeletal changes, it also inhibits neutrophil motility and activity, leading to a net anti-inflammatory ef...

Enzyme

...edback inhibition mechanism, where the product (P) inhibits the committed step (A->B). (2) Sequential feedbac...ocked. This leads to a buildup of C, which in turn inhibits the first common committed step A->B. (3) Enzyme multiplicity. Each end product inhibits both the first individual committed step and one o...

Insulin

...ake – forces cells to absorb circulating amino acids; lack of insulin inhibits absorption increased potassium uptake – forces cells to absorb serum potassium; lack of insulin inhibits absorption arterial muscle tone – forces arterial wall muscle to ...

Neurotransmitter

...MPT prevents the conversion of tyrosine to L-DOPA , the precursor to dopamine; reserpine prevents dopamine storage within vesicles; and deprenyl inhibits monoamine oxidase (MAO) B and thus increases dopamine levels. Diseases may affect specific neurotransmitter pathways. For example, Parkinson's di...

Tubulin

...uring mitosis. Pharmacology Tubulins are targets for anticancer drugs like taxol . The anti- gout agent colchicine binds to tubulin and inhibits microtubule formation, arresting neutrophil motility and decreasing inflammation . ...
inhibits in Biological Dictionary

Tetracycline

... synthesis inhibitor. It is commonly used... Tetracycline antibiotics are protein synthesis inhibitors, inhibiting the ... Tetracycline inhibits cell growth by inhibiting translation. ... Tetracycline ... Tetracycline , is used to treat bacterial infections, including pneumonia and ... ...

Telomere

...fication and deletion ... Negative regulator of telomere length (telomerase-dependent pathway) ... Tankyrase-mediated ADP-ribosylation of TRF1 inhibits binding to telomere repeats ... ...

S phase

...ion ... This page describes S phase control in fission yeast, and provides links to ... Damage to DNA after S phase (the G2 checkpoint), inhibits the action of Cdk1 ... A check on the successful replication of DNA during S phase . ... S phase - The second, middle part of interphase...

RNA interference

...nhibition of gene expression by small double ... use of RNA interference for artificially ... RNA interference (RNAi) is a process that inhibits the flow of genetic ... Zamore PD (2006) Essay: RNA interference : big applause for silencing in Stockholm. ... This chapter of the Promega Prot...

Repressor

...s by decreasing the rate of transcription. This blocking of expression is called repression. The lac repressor is a DNA-binding protein which inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria. It is active in the absence of lactose, ensuring ...

RecA protein

... buffer should be used with RecA Protein ? ... The Escherichia coli RdgC protein is a potential negative regula- tor of RecA function. RdgC inhibits RecA protein -promoted DNA ... In this case the mutant RecA protein is unable to bypass the medial heterology ... However RecA (wt) protei...
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Breaking Medicine News(10 mins):Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the ... APAC Region 2015-2019"  report to their offering. ... market is advances in technology. With continuous advances ... solutions to the latest standard that meets the ...
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(Date:12/10/2014)... , Dec. 08, 2014 Research and Markets ... addition of the "Biometrics Market in Japan ... http://photos.prnewswire.com/prnh/20130307/600769 The ... such as rural banking and upgradation of the ... witnessed in the market. Besides the aforementioned projects, ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
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