Gene Therapy Cures Inherited Liver Disease In Rats
A single dose of gene-virus combination cured rats of a inherited liver disease in which lack of a gene causes the accumulation of bilirubin –which, untreated, results in jaundice and brain damage, said researchers at Baylor College of Medicine in a report in the Proceedings of the Natural Academy of Sciences. "This is the first time this disease (Crigler-Najjar syndrome) has been complete...Genetic therapy reverses nervous system damage in animal model of inherited human disease
By injecting a therapeutic gene directly into the brain, researchers have treated a naturally occurring genetic disease in cats. This is the first genetic disease affecting the central nervous system to be successfully treated in an animal larger than mice and rats. If this approach can be successfully applied to humans, say the researchers, it might one day treat an entire class of diseases call...Tendency to hair loss inherited from the mother
It begins with receding hairlines, the forehead becomes higher, the hair at the back of the man's head gets thinner and thinner. Every second man suffers from greater or lesser hair loss. There are hardly any successful counter-measures ?despite an enormous range of obscure lotions and tinctures. It has long been suspected that hereditary factors are important in causing hair loss. However...Gene therapy cures inherited liver disease in rats
A single dose of gene-virus combination cured rats of a inherited liver disease in which lack of a gene causes the accumulation of bilirubin –which, untreated, results in jaundice and brain damage, said researchers at Baylor College of Medicine in a report in the Proceedings of the Natural Academy of Sciences. "This is the first time this disease (Crigler-Najjar syndrome) has been complet...Defective Gene Linked to Two Inherited Immune Deficiencies
Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics. The discovery may lead to new diagnostic tests for these two inherited conditions ?immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID). Currentl...Inherited gene important in ovarian cancer
A gene causes significant complications in ovarian cancer. A gene implicated in inherited ovarian cancer is more significant in the disease than previously realised. Up to 10 per cent of cases of ovarian cancer arise from a mutation in a gene called BRCA1.// In these cases, the woman usually has a strong family history of the disease. We know that BRCA1 prevents tumours from developing, although...Sudden Cardiac Death due to inherited Heart Disease
Unexplained sudden cardiac death is termed sudden arrhythmic death syndrome or SADS.Over 1,000 individuals die suddenly each day in the United States.// Most of these sudden deaths involve middle-aged or elderly individuals with heart problems. While sudden deaths in young people are rare, experts say they do have a tremendous impact on the medical community and the families. Previous...Persistent Childhood Wheeze Probably Inherited
Childhood wheezing has been linked to many different causes, some of which are typical of childhood asthma and some // of which are not. Previous studies have suggested early onset wheezing is associated with high levels of allergies, impaired lung function, and bronchial hyper-responsiveness. Children with the longest duration of wheezing also appear to have more severe asthma. However, some chi...Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Thrombotic Risk, Inherited Etiologies (Uncommon)
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Introgen's Advexin Demonstrates Clinical Benefit in Inherited Cancer
AUSTIN, Texas--(BUSINESS WIRE)--May 30, 2007--IntrogenTherapeutics, Inc. (NASDAQ:INGN) announced today the publication ofdata describing the dramatic clinical benefit of its lead productAdvexin in a patient with a rare inherited form of cancer known asLi-Fraumeni Syndrome (LFS), a genetic disorder characterized byinherited mutations i...