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Influenzae in Medical News

Supply of Key Children's Vaccine Almost Back to Normal

..., the agency recommended that parents forego booster shots for Haemophilus influenzae type B (Hib), an infection that can lead to bacterial meningitis. A booste...noted that tracking Hib cases isn't easy. There are many different types of influenzae and there are many steps involved in testing and reporting the various type...

Advanced Life Sciences Announces Posting of Briefing Documents for FDA Advisory Committee Meeting on Restanza(TM) (cethromycin)

... of death in the United States. CAP and other respiratory tract infections are caused by pathogens such as Streptococcus pneumoniae and Haemophilus influenzae . CAP affects 5.6 million patients in the United States each year, with 10 million physician visits and 2 million hospitalizations occurring annually....

J. Craig Venter Institute Awarded $43 Million, Five Year Contract From NIAID to Continue to Develop and Provide Sequencing, Genotyping, and Bioinformatics Expertise and Services in Infectious Diseases

...es makes our work more necessary than ever," said J. Craig Venter, Ph.D., founder and president, JCVI. "Since our first sequencing of the Haemophilus influenzae genome in 1995, to our most recent work in sequencing the isolates from the 2009 H1N1 flu outbreak, JCVI is committed to being a major source for lea...

Pediatric Ear Infection Vaccine Shows Promise

...ek for three weeks. A fourth group received a placebo. After receiving the vaccines or placebo, the animals were infected with nontypeable haemophilus influenzae (NTHi), one of the three main bacterial causes of otitis media, an infection/inflammation of the middle ear. The chinchillas that received the vacc...

Sanofi-aventis Announces Good First-quarter 2009 Performance

...oosted by the success of Pentacel (R) , the first 5-in-1 pediatric combination vaccine against diphtheria, tetanus, pertussis, polio and haemophilus influenzae type b to be licensed in the United States. Launched in the United States in July 2008, Pentacel(R) achieved net sales of euro 73 million in the first...

Smoking Ups Infection Risk for Lung Disease Patients

...mice was exposed to cigarette smoke for four days. After the cigarette smoke exposure, both groups of mice received a dose of nontypeable Haemophilus influenzae (NTHI) bacteria, which causes many COPD exacerbations. Mice in a control group weren't exposed to cigarette smoke but were inoculated with NTHI. ...

Cigarette smoke may alter immune response in COPD exacerbations

...how cigarette smoke would change the inflammatory response to the bacteria that is the culprit behind many COPD exacerbations, nontypeable Haemophilus influenzae or NTHI." Their results were published in the second issue of April of the American Journal of Respiratory and Critical Care Medicine . Dr. Stm...

Sagent Pharmaceuticals Announces U.S. FDA Approval of Azithromycin for Injection

...eptible strains of the designated microorganisms in the following conditions: community-acquired pneumonia due to Chlamydia pneumoniae , Haemophilus influenzae , Legionella pneumophila , Moraxella catarrhalis , Mycoplasma pneumoniae , Staphylococcus aureus , or Streptococcus pneumoniae in patients who r...

FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia

...eptible isolates), including cases with concurrent bacteremia, Haemophilus influenzae (beta-lactamase negative isolates), and Legionella pneumophila . In... in vitro profile of TYGACIL has now been expanded to include: Haemophilus influenzae (ampicillin-resistant) and Haemophilus parainfluenzae . The clinical si...

Sanofi-aventis Delivers 2008 Results Above Guidance

...ne to protect against diphtheria, tetanus, pertussis, polio and haemophilus influenzae type b licensed in the United States-- confirmed its success with strong sa...hich protects against diphtheria, tetanus, pertussis, polio and haemophilus influenzae type b -- in the "other countries" region. EUR million ...
Influenzae in Medical Technology

Advanced Life Sciences Announces Outcome of FDA's Anti-Infective Drugs Advisory Committee Review of Restanza(TM) (cethromycin)

... of death in the United States. CAP and other respiratory tract infections are caused by pathogens such as Streptococcus pneumoniae and Haemophilus influenzae . CAP affects 5.6 million patients in the United States each year, with 10 million physician visits and 2 million hospitalizations occurring annually....

Novexel to Present Four Posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases in Helsinki

...tant Staphylococcus aureus (MRSA) and organisms responsible for lower respiratory tract infections, including Streptococcus pneumoniae and Haemophilus influenzae , (Poster P 1393). The second poster contains in vivo data demonstrating that, following oral administration, NXL103 was able to kill intracellular dr...

Two New Studies in the New England Journal of Medicine Show Malaria Vaccine Candidate Advancing in Africa

...to each of the vaccine components. The childhood vaccine contained antigens for Diphtheria (D), Tetanus (T), whole-cell pertussis (Pw) and haemophilus influenzae B (Hib). In countries where a malaria vaccine is needed most, the current immunization schedule for infants, called the WHO Expanded Program on Immuni...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Next Generation Oxazolidinone at 2008 ICAAC/IDSA Joint Meeting

...roshauer, PhD, President and CEO of Rib-X Pharmaceuticals. "In particular, radezolid offers a broader spectrum that includes atypicals and Haemophilus influenzae and a once-a-day option at a significantly lower dose than linezolid. Additionally, these results further validate Rib-X's proprietary discovery and d...

Steroids Provide No Survival Benefit for Children With Bacterial Meningitis

... Previous studies had shown that corticosteroids had a clear benefit in preventing hearing loss in children whose meningitis was caused by Hemophilus influenzae type b (Hib) bacteria. However, since the Hib vaccine was approved for routine use in childhood immunizations in 1985, cases of Hib meningitis have dr...

Annual Conference on Vaccine Research to Highlight Not Only Health Benefits But Also Economic Gains

... conference's first Robert Austrian Memorial Lecture. Dr. Levine is an expert on respiratory infections in developing countries, including Haemophilus influenzae type B (Hib) and Streptococcus pneumoniae. He currently heads a $30 million effort by the Global Alliance for Vaccines and Immunization aimed at getti...

Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... In Vitro Activity of Cethromycin Against Strains of Haemophilus Influenzae" Cethromycin demonstrated potent in vitro activity against all Haemophius influenzae isolates studied regardless of beta-lactamase status. Based on the MIC data, cethromycin potency was comparable to telithromycin and azithromycin, and...

Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... In Vitro Activity of Cethromycin Against Strains of Haemophilus Influenzae" Cethromycin demonstrated potent in vitro activity against all Haemophius influenzae isolates studied regardless of beta-lactamase status. Based on the MIC data, cethromycin potency was comparable to telithromycin and azithromycin, and...

Advanced Life Sciences to Present Data on Selected Cethromycin Therapeutic Studies at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

...n Against Strains of Streptococcus pneumoniae -- Poster E-1631: Assessment of In Vitro Activity of Cethromycin Against Strains of Haemophilus influenzae -- Poster E1634: Antimicrobial Activity of Cethromycin, a Novel Ketolide, Tested against a Diverse Collection of Francisella tularensis Strains ...
Influenzae in Medical Products

Haemophilus influenzae b Antibody, IgG

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Directigen™ N. meningitidis Group B/ E. coli K1 Test Kit

Description:...he Directigen™ Meningitis Individual Tests are presumptive latex slide agglutination tests for the direct qualitative detection of antigens to H. influenzae type b, S. pneumoniae, N. meningitidis Group B and Escherichia coli K1 in cerebrospinal fluid (CSF), serum or urine....
Company:BD Diagnostic Systems
Influenzae in Medical Dictionary

Infections

... Staphylococcal infections , children, MRSA ... Infections . Kidney and Urinary Tract Disorders. Liver and Gallbladder Disorders ... Haemophilus influenzae Infections . Symptoms and Diagnosis. Prevention and ... ... kinds of E. coli can cause diarrhea, while others cause urinary tract infections ,...

Hib

... Haemophilus influenzae type B vaccine is a conjugate vaccine develope...ion of invasive disease caused by Haemophilus influenzae type b bacteria. The Centers for Disease Control a...ib vaccine. Due to... Learn about haemophilus influenzae type B and Hib vaccine. ... How do you catch Hi...

Epiglottitis

... is an emergency condition that blocks the flow of air into your lungs. ... The most common cause of epiglottitis is infection with Haemophilus influenzae ... Epiglottitis : Provides comprehensive information concerning causes, Epiglottitis , including what to do, what to expect and when to call th...

Antiserum

... the Day, and word games. ... Listeria Antiserum , Listeria Antigen, Mycobacterium, Neisseria Meningitidis, ... DIFCO ANTISERUM ... Haemophilus influenzae Antiserum Poly. 1mL $134.40. 222501 ... Pronunciation of antiserum . antiserum synonyms. antiserum usage examples and antiserum quotes. ....
Influenzae in Biological News

Genome Sequence for Haemophilus Influenzae Completed

Otters cavorting in the water is a scene with which we're all familiar. Yet, unlike many other mammals that spend a considerable amount of time in the water–polar bears, seals, dolphins, and whales–river otters do not have a thick layer of body fat to keep warm. They rely, instead, on a few unique ...

Preventing ear infections in the future: Delivering vaccine through the skin

..., inexpensive and potentially transformative way to deliver vaccines," says Laura Novotny, one of the study researchers. Nontypeable Haemophilus influenzae (NTHi) is one of the three main bacterial causes of otitis media (OM), an infection or inflammation of the middle ear. OM is one of the most signific...

Breakthrough in the treatment of bacterial meningitis

...is in childhood is almost exclusively caused by the respiratory tract pathogens Streptococcus pneumoniae , Neisseria meningitidis , and Haemophilus influenzae . The mechanism used by these lethal germs to break through the blood brain barrier (BBB) has, until now, been unknown. The team led by Dlawer Ala...

Nanoemulsion potent against superbugs that kill cystic fibrosis patients

... than 400 nanometers in size. These emulsions have already proved to be non-toxic, potent killers of bacteria such as Streptococcus pneumoniae, H. influenzae and gonorrhea, of viruses such as herpes simplex and influenza A, and of several fungi. Nanoemulsion treatments for cold sores and toenail fungus are ...

Vaccines and autism: Many hypotheses, but no correlation

...g down immunization rates and having a real impact on public health, he added. Vaccine refusal is contributing to the current increase in Haemophilus influenzae cases in Minnesotaincluding the death of one childand was a factor in last year's measles outbreak in California. The controversy began with a 1998...

Just a little squeeze lets proteins assess DNA

...e structure of a protein called HincII that snips up DNA. The protein is a type of enzyme called a restriction endonuclease and comes from Haemophilus influenzae bacteria. Since that time, Horton has been trying to learn how HincII interrogates the DNA to find the right place to cut. The protein protects...

Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes

...ne system would fail to detect. "With conjugate technology, NIH researchers have developed effective vaccines against such scourges as Haemophilus influenzae type B meningitis and typhoid fever," said Elias A. Zerhouni, M.D., Director of the National Institutes of Health. "The experimental malaria vaccine ...

Study suggests that publicly available genome data may contain small but significant errors

... Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been...

$5.1 billion would save 6 million children

...lated to obtain the average cost to save a child's life. The cost of some of the interventions, such as vaccines to prevent infection with Haemophilus influenzae type b, may drop substantially as more extensive use reduces the price. According to the study authors, full implementation of preventive intervent...
Influenzae in Biological Technology

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Radezolid in Community-Acquired Pneumonia

...ccus pneumoniae, methicillin-sensitive Staphylococcus aureus, Haemophilus influenzae and atypical respiratory pathogens . Additionally, radezolid was well to...erial CAP is most often caused by pathogens such as S. pneumoniae and H. influenzae . CAP affects approximately 5.6 million patients in the United States each ...

Advanced Life Sciences Receives Complete Response Letter From FDA for Restanza(TM) (Cethromycin) in Community Acquired Pneumonia

... of death in the United States. CAP and other respiratory tract infections are caused by pathogens such as Streptococcus pneumoniae and Haemophilus influenzae . CAP affects 5.6 million patients in the United States each year, with 10 million physician visits and 2 million hospitalizations occurring annually....

Sanofi-aventis Announces Second Quarter 2009 Results

...he first 5-in-1 pediatric combination vaccine licensed in the United States in June 2008 against diphtheria, tetanus, pertussis, polio and Haemophilus influenzae type b) reached euro 83 million for the quarter. Net sales of seasonal influenza vaccines rose by 3.3% to euro 32 million. In May 2009, the...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...at children receive a booster dose of Haemophilus influenzae type b (Hib) vaccine after 12 months of age. The...hort term. About Hib Disease Haemophilus influenzae type b, or Hib, is a bacterium that resides in th...myelitis, and invasive disease due to Haemophilus influenzae type b. Pentacel vaccine is approved for use in ...

Professor Hanna Nohynek Joins Encorium as Head Consultant of its Clinical Vaccine Research Team

...products. She has also recently been the Scientific Coordinator and/or co-investigator in seven Phase II trials on a number of vaccines ( Haemophilus influenzae type b, meningococcal conjugate, and pneumococcal conjugate among infants, and pneumococcal polysaccharide among pregnant mothers and infants), as we...

Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants

...'s IPV containing pediatric combination vaccine, Pentaxim(R) (Diphtheria, tetanus, acellular pertussis, inactivated poliomyelitis vaccine, Haemophilus influenzae type b conjugate vaccine). Turkey also chose to include Pentaxim(R) in its national immunization program. In Indonesia the World Health Organization...

Innovative Fosshield(R) Antimicrobial Technology Shown to Continuously Kill MRSA 'Superbug'

...uously kill MRSA and a number of other bacteria including Streptococcus pyogenes (strep), Legionella pneumonphila (Legionnaries' disease), Haemophilus influenzae (flu) and Tuberculosis (TB). Results indicated a consistent and significant reduction in bacteria after one hour. More extensive evaluation studies ar...
Influenzae in Biological Definition

Genetics

...estriction enzymes were discovered in studies of a bacterium, Haemophilius influenzae , enabling scientists to cut and paste DNA 1977 DNA is sequenced for ... in this gene cause cystic fibrosis 1995 The genome of Haemophilus influenzae is the first genome of a free living organism to be sequenced 1996 Sa...

Genomics

...uenced in its entirety was that of bacteriophage FX174 (5,368 kb) in 1980 . The first free-living organism to be sequenced was that of Haemophilus influenzae (1.8Mb) in 1995 , and since then genomes are being sequenced at a rapid pace. A rough draft of the human genome was completed by the Human Genome P...

Restriction enzyme

...ns 5'GGATCC 5'---G GATCC---3' 3'CCTAGG 3'---CCTAG G---5' HindIII Haemophilus influenzae 5'AAGCTT 5'---A AGCTT---3' 3'TTCGAA 3'---TTCGA A---5' MstII Microcoleus sp...
Influenzae in Biological Dictionary

Phase variation

...on and off at high frequencies. ... We have examined phase variation in more detail, and we report that in most P ... Phase variation of H. influenzae fimbriae: Transcriptional control of two ... is subject to reversible phase variation between three expression levels. ... Providing a micro...
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