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Inactivated in Medical News

Sanofi Pasteur Begins Shipments of Fluzone(R), Influenza Virus Vaccine for 2009-2010 Seasonal Influenza

... vaccine licensed in the United States for children as young as 6 months of age through adults. Sanofi Pasteur, the only U.S. manufacturer of inactivated influenza vaccine, is committed to supporting the U.S. Centers for Disease Control and Prevention's (CDC) recommendation for annual immunization again...

Eliminating polio requires global, coordinated effort -- Health Affairs article highlights risks, rewards of eradication

...al fronts, including lowering the cost for poor countries to vaccinate with inactivated polio vaccine (IPV), says a leading global health researcher in the July/Au...ill depend as much on the steps being taken now to improve the economics of inactivated polio vaccination," he concludes. In a related paper, Judith Kaufmann an...

Intercell Supports the Japanese Encephalitis Vaccination Recommendations of CDC's Advisory Committee on Immunization Practices

...l who live in or travel to areas where the virus circulates. About IXIARO Intercell's novel Japanese Encephalitis vaccine is a purified, inactivated vaccine for active immunization of adults against the Japanese Encephalitis virus. The total development time for this vaccine was more than 10 years....

New Vaccine from Intervet/Schering-Plough Animal Health is First for Canine Influenza Virus

...een demonstrated to reduce the incidence and severity of lung lesions, as well as the duration of coughing and viral shedding. The vaccine, made from inactivated virus, is intended as an aid in the control of disease associated with canine influenza virus infection, a type A, subtype H3N8. It is administered b...

Health Secrets of Red Wine Uncovered

... improve blood supply to cells. Scientists are also studying how the body absorbs resveratrol into the blood stream, since the compound is largely inactivated in the gut and liver. "Most of the resveratrol in imbibed red wine does not reach the circulation," Stephen Taylor, a professor of pharmacology at...

U-M researchers link pathway to breast cancer stem cells

... journal from the Public Library of Science. PTEN is the most frequently inactivated tumor suppressor gene in several cancers, including breast cancer, where it is inactivated in about 40 percent of patients. PTEN is linked to poor outcomes and is ass...
Inactivated in Medical Technology

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...voltage-gated sodium channel blocker designed to selectively inhibit the rapid firing of nerve cells that causes seizures. It specifically targets the inactivated state of the ion channel, preventing its return to the active state, and thereby reduces repetitive neuronal firing. The efficacy of ESL has been demo...

Plasma Products Safe Despite Swine Influenza Outbreak, Assures International Biopharmaceutical Company Octapharma

...ve and unable to infect. All influenza viruses are lipid enveloped viruses and not very resistant to inactivation. The H1N1 virus is completely inactivated by the procedures used in the manufacture of Octaplas(R) and other blood-derived biopharmaceutical products. Notes for editors Octaphar...

Nobilon Advances First Vaccine Into Human Trials - Intranasal Influenza Vaccine Begins Phase I Clinical Development

...althy adults. Vaccination of elderly generally has a lower impact on prevalence, but is up to 80% effective in preventing death. Nevertheless, current inactivated influenza vaccines have limitations and are underutilized. Intramuscular vaccination with needles is an important barrier for the acceptance of annual...

Millennium Presents New Data on Investigational Drugs for Novel Cancer Targets at EORTC-NCI-AACR Symposium

...vorable pharmacokinetics and tumor distribution, efficacy in EGFR- and HER2-expressing xenograft models, activity in tumors harboring activated RAS or inactivated LKB1 mutations and activation of AMPK pathways in cardiac cells. -- Tyrosine kinase inhibitors, such as TAK-285, GW572016 or SU11248, protect ...

Sinovac Initiates Phase II Volunteer Enrollment for Split Viron Pandemic Influenza (H5N1) Vaccine

...r 2007, Sinovac reported positive top-line results from the completed Phase II clinical trial of Panflu(TM), its pandemic influenza (H5N1) whole viron inactivated vaccine. In April 2008, Panflu(TM) was granted a production license by the China State Food and Drug Administration (SFDA). Panflu(TM) is the first an...

Juvaris BioTherapeutics Announces Cooperative Research and Development Agreement With The Centers for Disease Control and Prevention

... up to fifty-fold, which would be beneficial in case of limited vaccine supply during an influenza pandemic. Furthermore, preclinical experiments with inactivated virus have shown greater cross-protection when our adjuvant is used." About Juvaris Juvaris BioTherapeutics was created in 2003 to develop an immu...
Inactivated in Medical Products

Candida albicans IgG / IgM / IgA ELISA

Description:... antigens used in Virion\Serions assay systems are produced in their own laboratories under the control of their experienced staff. These antigens are inactivated and non-infectious and available to our customers as stand-alone products....
Company:QED Bioscience Inc.

SERODIA®-Chagas

Description:...ibodies to Trypanosoma cruzi in human serum/plasma. This test is based on Fujirebio's particle-agglutination assay using gelatin particles coated with inactivated Trypanosoma cruzi antigens. These coated gelatin particles are agglutinated in the presence of antibodies to Trypanosoma cruzi in human serum/plasma....
Company:Fujirebio Diagnostics, Inc.

QualiCode™ B. burgdorferi IgG/IgM Western Blot Kits

Description:...IgG/IgM Western Blot Kits provide a sensitive and specific means for detection of antibodies to Borrelia burgdorferi. Proteins from the spirochete are inactivated by detergent disruption. Purified B. burgdorferi antigens are fractionated according to molecular weight by electrophoresis on a polyacrylamide slab g...
Company:Immunetics, Inc.

XSera Rapid HIV-1/2 Antibody Controls

Features:... Liquid-ready (no reconstitution required) Evaluated on FDA cleared rapid HIV kits 60 day open-bottle storage (room temperature) Heat inactivated human plasma with antibodies to HIV-1 or HIV-2 Convenient plastic screw top vial ...
Company:RNA Medical

Liquichek Seroconversion Panels

Features:... of time Panels are native, naturally occurring, undiluted single donor plasma Panels are neither pooled patient samples nor prepared from viral inactivated cell lines Sufficient numbers of vials in each kit to detect a slow rise in titer Panels are at clinically significant levels appropriate for as...
Company:Bio-Rad Laboratories

Liquichek Antigen Panels

Features:... Panels are native, naturally occurring, undiluted donor samples Panels are neither pooled patient samples nor prepared from viral inactivated cell lines Panels are at clinically significant levels appropriate for assay evaluation comparison studies ...
Company:Bio-Rad Laboratories
Inactivated in Medical Definition

Artificial induction of immunity

...ed the infectious agent from anthrax . He then derived a vaccine by altering the infectious agent so as to make it harmless and then introducing this inactivated form of the infectious agents into farm animals, which then proved to be immune to the disease. Pasteur also isolated a crude preparation of the inf...
Inactivated in Medical Dictionary

Typhoid

...ices. In PDF format. Explains the causes, symptoms, diagnosis, treatment, and prevention using a fictitious medical case of typhoid fever. inactivated Typhoid Vaccine (Shot) • Should not be given to children younger than 2 ... Typhoid causes a high fever, weakness, stomach ... Typhoid is ...

Spores

...ed in each ... The collateral spread of exposure to spores was a sobering reminder of the ... Samples suspected of containing spores should be inactivated with 10 ... These spores , each of which can develop into a new anthrax bacterial cell, are ... Spores may survive in an environment for ma...

Influenza immunization

...eed only one dose in their first season of immunization . ... Influenza Immunization . Two types of influenza vaccine are now available: inactivated (or killed) ... Side Effects from Influenza Immunization ... ... strong voice the need to make influenza immunization a national health ...

Aflatoxins

... byproducts produced during the growth of several ... In South Dakota, aflatoxins are primarily a problem in corn but can ... Aflatoxins are inactivated by a wide range of reagents. ... The aflatoxins are synthesized by the filamentous fungus Aspergillus flavus and ... Aflatoxin ,toxin,micotox...
Inactivated in Biological News

Pushmi-pullyu of B-cell development discovered

...d both EBF and the two chromatin remodeling complexes. When the researchers inactivated the SWI/SNF complex, that activation fell to 8-fold, suggesting that SWI/SNF helped promote B-cell development. When they inactivated Mi-2/NuRD instead, expression of the B-cell gene increased 1,727-fold. Mi-2...

How an enzyme tells stem cells which way to divide

... is pretty simple," he said, when viewed from a biochemical perspective. "What happens is that Miranda gets phosphorylated by aPKC, turning it into an inactivated substrate and pushing it into another location in the cell." Much of the paper in Current Biology is devoted to why the more complex scenarios are ...

Phasic firing of dopamine neurons is key to brain's prediction of rewards

...The research has significant applications for the improvement of health, because the dopamine neurons we are studying are the same neurons that become inactivated during Parkinson's Disease and with the consumption of psychostimulants such as cocaine and amphetamine," said Paladini, who is also a member of UTSA'...

Two Hutchinson Center researchers named HHMI Early Career Scientists

...Hutchinson Center, Taniguchi studies the role of DNA repair in promoting drug resistance in cancer cells. He identified a repair pathway that is often inactivated in patients with breast and ovarian cancers, as well as the childhood predisposition to cancer known as Fanconi anemia. Reactivation of the pathway, h...

Newly discovered gene plays vital role in cancer

...uture cancer therapies. "Mutations in the p53 gene contribute to about half of all cancer cases," she says. "In the remaining half, p53 is probably inactivated in other ways, such as damage to Wrap53 knocking out the production of the p53 protein." The study is also one of the first to show how antisense R...

Suppressing cancer with a master control gene

...n cancer in mice. The gene regulates the last step in the specialization to epithelial cells of the colon. Humans with colon cancer frequently have an inactivated ATOH1 gene, the researchers show. The researchers could reactivate the gene in human colon cancer cells grown in culture. This caused the tumor cel...
Inactivated in Biological Technology

Sinovac Enters Veterinary Vaccine Market with Inactivated Rabies Vaccine

BEIJING, Jan. 26 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. (NYSE Alternext US: SVA), a leading provider of vaccines in China, today announced its wholly owned subsidiary, Tangshan Yian Biological Engineering Co., Ltd, has obtained approval from China's Ministry of Agriculture to conduct field ...

Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants

Sanofi Pasteur and Chumakov Institute Russian Academy Medical Sciences Providers of Inactivated Polio Vaccine (IPV) IMOVAX PolioTM for Russia National "Project Health" PARIS, November 12 /PRNewswire-FirstCall/ -- Sanofi Pasteur, the vaccines division of sanofi-aventis...

Sinovac Initiates Clinical Trials for Inactivated Hepatitis A Vaccine in Ukraine

BEIJING, Sept. 15 /Xinhua-PRNewswire/ -- Sinovac Biotech Ltd. (Amex: SVA), a leading provider of vaccines in China, today announced the initiation of clinical trials in Ukraine for its inactivated hepatitis A vaccine, Healive, in September, 2008. The trials are being conducted by Biolik Biopha...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...for Hib vaccination through the use of its two Hib-containing vaccines: Pentacel(R) (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, inactivated Poliovirus and Haemophilus b Conjugate [Tetanus Toxoid Conjugate] Vaccine) and ActHIB(R) (Haemophilus b Conjugate Vaccine [Tetanus Toxoid Conjugate])....

Sinovac Completes Construction of H1N1 Virus Seed Bank

...ese encephalitis vaccine, and human rabies vaccine. Its wholly owned subsidiary, Tangshan Yian, is conducting field trials for independently developed inactivated animal rabies vaccines. Safe Harbor Statement This announcement contains forward-looking statements. These statements are made under t...

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

...randomized to receive Prevenar 13 or Prevenar along with Infanrix hexa(R) [GlaxoSmithKline], the combined diphtheria, tetanus, pertussis, hepatitis B, inactivated poliovirus, and Hib vaccine, at 3, 5, and 11 months of age. Assessment of functional antibody levels (serotype specific opsonphagocytic assay) one mo...
Inactivated in Biological Products

Newborn Calf Serum, Heat Inactivated from Sigma-Aldrich

Description: Collected from calves that are 10 days old or less. Sterile, cell culture tested, US Origin...
Company:Sigma-Aldrich

Mouse Anti-Salmonella 0 - 12 A B D group Monoclonal Antibody, Unconjugated, Clone 10D9H from ABR-Affinity BioReagents

Description:... Immunogen: Heat inactivated bacterial cells of Salmonella enteriditis,paratyphi and typhimurium Storage: 4 C...
Company:ABR-Affinity BioReagents

Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 8C11C from ABR-Affinity BioReagents

Description:... Salmonella typhimurium Immunogen: Heat inactivated bacterial cells of Salmonella typhimurium B Storage: 4 C...
Company:ABR-Affinity BioReagents

GeneRacer 3' Nested Primer from Invitrogen

Description:...e Transcriptase (RT) for improved amplification of the full-length 5 end from long and complex mRNA. The RNase H portion of SuperScript II RT has been inactivated to avoid cleaving mRNA during cDNA synthesis. This increases the size and yield of cDNA. SuperScript II RT is more thermostable than wild-type RTS. Th...
Company:Invitrogen

Tritirachium album Proteinase K from USB Corp.

Description:...0.05 - 1 mg/ml Activators: Stimulated by 0.2 - 1% SDS or 1 - 4M urea (8) inactivated by PMSF (1) ; Not inactivated by EGTA, thiol reagents or trypsin/chymotrypsin inhibitors (1) Form: Ly...
Company:USB Corp.

Anti-Taq Monoclonal Antibody, Unconjugated from eEnzyme LLC

Description:...he onset of thermal cycling, preven-ting nonspecific amplification and primer-dimer formation. When the temperature is raised, the antibody is quickly inactivated and PCR proceeds...
Company:eEnzyme LLC
Inactivated in Biological Definition

Lyon hypothesis

...hesis states that in cells with multiple X chromosomes , all but one is inactivated during mammalian embryogenesis . X-inactivation leads to clumped chroma...f Barr bodies is called Lyonization . In humans the X chromosome that is inactivated is determined by chance. In marsupials , however, the paternal X chromosom...

Vaccine

...ivial infections. Vaccines may also be killed or inactivated organisms or purified products derived from them. ...are three types of traditional vaccines [1] : inactivated - these are previously virulent micro-organisms th...s , rubella , and mumps . Toxoids - these are inactivated toxic compounds from micro-organisms in cases wher...

X chromosome

...opment in females, one of the two X chromosomes is randomly and permanently inactivated in somatic cells (cells other than egg and sperm cells). This phenomeno...and hence two copies of each gene. One of the two chromosomes appears to be inactivated ( Lyonization ) into a Barr body , and it was previously assumed that only...
Inactivated in Biological Dictionary

X chromosome

...tains considerably more genes than the Y, which has its ... The sex chromosomes raise an interesting dilemma: females (XX) carry twice as ... The inactivated X chromosome then condenses into a compact structure called a ... A single-source launchpad to information about each human chromosome . ......

Spermatogenesis

...he ... SPERMATOGENESIS . Spermatogenesis is the process of sperm cell development. ... the X chromosome that inhibit spermatogenesis are inactivated in XY somatic cells. ... Shop for Proteomics of Spermatogenesis - Books at Shop.com. Books|Non-Fiction|English |Hardcover|Science|Springer Verl...

Gene modification

... Unambiguous demonstration of triple-helix-directed gene modification ... To monitor endogenous gene modification by TFOs in a yeast model, we inactivated ... DELIVERY STRATEGIES FOR MYOCARDIAL GENE TRANSFER IN PRECLINICAL STUDIES ... with the differentiation potential of the cells after gene ...

Diploid Cell

...oid c four ... Human diploid cell vaccine A rabies vaccine in which the virus is grown in cultures of human cells , concentrated, and inactivated for IM or ID Mitosis produces cells with diploid numbers of chromosomes--46 in ... They reproduce by mitosis and have a diploid number of c...
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