NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma
A team of researchers, led by Steven A. Rosenberg, M.D., at the National Cancer Institute, part of the National Institutes of Health, have found that patients with advanced melanoma who had not responded to previous therapies experienced a significant reduction in the size of their cancers as a result of receiving a new immunotherapy. This immunotherapy consisted of a combination of chemotherapy...First SCID gene chip to be introduced at Academy meeting on immunodeficiencies
The first gene chip ever to be developed for detecting SCID (primary immunodeficiency) in newborns will be presented to researchers for the first time at the New York Academy of Sciences' and Jeffrey Modell Foundation's one-day conference, Primary Immunodeficiencies: Past, Present, Future. The meeting will take place on April 25 at Rockefeller University, Caspary Auditorium, 1230 York Avenue, NY...Chemical guidance of T cells leads to immunologic memory and long-term immunity
In the latest issue of the journal Nature, scientists at the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) describe a new understanding about how long-term immunity works--findings that may lead to new ways of thinking about how to enhance certain immune responses and how to improve vaccines. Led by immunologist Ronald Germain, M.D...Immune cell communication key to hunting viruses, Jefferson immunologists show
Immunologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have used nanotechnology to create a novel "biosensor" to solve in part a perplexing problem in immunology: how immune system cells called killer T-cells hunt down invading viruses. They found that surprisingly little virus can turn on the killer T-cells, thanks to some complicated communication amon...Human CALCA EIA (Enzyme immunoassay) Kit, Host: Rabbit ; Extraction-free from BACHEM
Description:Antigen sequence: H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH )-&alpha...FLAG Immunoprecipitation Kit from Sigma-Aldrich
Description:Sigmas FLAG Immunoprecipitation kit allows a rapid and efficient immunoprecipitation and elution of an active FLAG-tagged protein. The immunoprecipitation is performed with ANTI-FLAG-M2 affinity gel, which is a highly specific monoclonal antibody covalently attached to agarose resin. The use of affinity resin allows an efficient binding of FLAG-tagged proteins without the need for preliminary ste...Catch & Release v2.0 High Throughput (HT) Immunoprecipitation Assay Kit- 96 well from Upstate
Description:This kit allows for quick and reproducible immunoprecipitation (IP) by using a 96 well filter plate. The system is more reproducible than regular IPs, which are problematic with regards to washing the protein A/G agarose without disrupting the agarose bed. The binding of the antibody/antigen complex in Catch and Release is reversible, and elution of the immune complex can occur with native or den...Terminal deoxynucleotidyl transferase (TdT) Immunofluorescence Assay Kit from AbD Serotec
Description:Terminal deoxynucleotidyl transferase (TdT) is an intracellular marker normally present at high levels in cortical thymocytes and minor subpopulation of bone marrow prelymphocytes. Elevated levels of the enzyme and increased numbers of TdT cells are found to be associated with some lymphoblastic leukaemias and lymphomas. Presence of TdT thus provides a useful adjunct in the differentiation of leu...Model 1575 Immunowash Microplate Washer from Bio-Rad
Description:The Model 1575 immunowash microplate washer, 100-240 V, is used for washing 96-well microplates that have flat-, U-, or V-bottom wells. This washer has programmability of horizontal and vertical needle positions to an accuracy of 0.1 mm for bottom washing, crosswise aspiration, and overflow washing. It can store up to 75 wash sequences for customized protocols and includes a bottle and tubing set...Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
Danny Q. Hoang Michael Browning Xinping Yang PeterPingerelli Stratagene Cloning Systems, Inc. Stratagene introduces affinity purified antibodies for NMDA receptorsubunits that are useful for studying expression of the NR2A, NR2B and NR2Csubunit proteins...Enzyme Immunoassay for Studying Intracellular Levels of cAMP
Sensitive, nonradioactive cyclic-AMP detection kit and adenylate cyclase(AC) toxin Stratagene Cloning Systems, Inc. American Qualex Stratagenes EIA cAMP Kit is a highly sensitive and specificantibody-based assay kit for no...Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B
Diana Davis, PhD, Aiguo Zhang, PhD, Chloe Etienne, Ivan Huang,and Michele Malit, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Drive,Hercules, CA 94547 USA Bio-Plex cytokine assays are bead-based multiplex sandwich immunoassays. The concentrations of analytes in a Bio-Plex cytokine immunoassay are...Real-Time Immuno-PCR on the iCycler iQ System, Rev A
Kristina Lind and Mikael Kubista, TATAA Biocenter, Medicinaregatan 7A/B,405 30 Gteborg, Sweden A technique for antigen detection, called immuno-PCR, was developed by Sano et al. (1992). It combines the molecular recognition of antibodies with the high DNA amplification capability of PCR. The procedu...Researchers Feel The Need For Standards Of Practice In Immunoglobulin Therapy
Nursing specialists feel that there is a requirement for having a standard of practice in immunoglobulin therapy. A review article published in the July/August 2005 Journal of Infusion Nursing examines the need for established treatment guidelines // to support doctors and nurses in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients w...Immunosuppressive drug shows promise in treatment of eye disorder
It is a routine practice to prescribe drugs called immunosuppressant to transplant patients to prevent the transplanted organs from being rejected. The medical community has only been interested in worrying about the problems caused due to immunosuppression. Looking at the other side of the coin, there seems to be benefits as well.// It has been found out that the immunosuppressive dr...Immunotherapy For Cancer Treatment
Dr. David McKean and Colleagues from Mayo clinic, is working on improving the host immune system by increasing the T cells by giving Anti-retroviral therapy with tumor components so that it produces immune cells specifically against the Cancer cells//. Anti-retroviral therapy has shown effective treatment against HIV treatment, by stimulating T cells against the virus by increasing the...Immunosuppressive Action Of Fungal Metabolite - Gliotoxin
Researchers from Japan have recently demonstrated the first evidence that mast cell is a direct target of gliotoxin. Fungal secondary metabolites such as gliotoxin, an epipolythiodioxopiperazine toxin produced by pathogenic fungi like Candida and Aspergillus//, possess immunosuppressive activities and have been thought to contribute to pathology of fungal infections in animals and human...Model 1575 Immunowash Microplate Washer
Description:Bio-Rad's Model 1575 immunowash microplate washer offers complete control of needle position to perform special wash routines and maximize wash efficiency. This system includes a large choice of wash that which facilitate easy wash protocol creation and storage....ADVIA Centaur Immunoassay System
Description:ADVIA Centaur delivers a new level of immunodiagnostic productivity. It provides the flexibility to integrate with any laboratory automation system, now and in the future. Most importantly, it offers a comprehensive disease-focused menu of immunoassays - a menu that is under constant expansion....When Volume Matters, Immunoassay Systems Deliver
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...Immunoassay Systems - Your Laboratory Workhorse
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...First Demonstration of nanoImmunology: a Nanomaterials-based Therapeutic Approach to Treat Allergy
ROANOKE, Va.--(BUSINESS WIRE)--Jun 20, 2007 - Researchers from LunaInnovations Incorporated (NASDAQ: LUNA) and Virginia CommonwealthUniversity (VCU) are the first to show that carbon nanospheres,sometimes referred to as "buckyballs," are able to block allergicresponse in human cell culture experiments and mice. These findingsare described in a paper entitled "Fullerene Nanomaterials Inhibit...