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ImmuKnow in Medical News

Cylex Announces Significant Expansions and Reassignments of Personnel

...ole in business development. About ImmuKnow(R) immuknow is the immune cell function assay cleared by the F...d from CD4 cells following cell stimulation. The immuknow test is a qualitative assay and does not directly ...uantify the level of immunosuppression. Results of immuknow assays should be used in conjunction with clinical...

Cell-Mediated Immunity and Anti-HLA Antibody Tests Provide Insight to Immune Response in Renal Transplant Patients

... "Cell-mediated immunity, as measured with Cylex's immuknow test, may indicate the effectiveness of augmented ...tly shown that immune function, assessed using the immuknow assay for cell-mediated immunity, may correlate wi...l sensitization in serially matched samples. The immuknow assay of cell-mediated immunity is used to measure...

Multiple Independent Studies Report on Use of Cylex's Immune Cell Function Assay in Postoperative Monitoring of Kidney, Liver, and Heart Transplant Recipients

...r report specifically on studies of the use of the immuknow assay or will include information on the use of th...ding of the possible applications of the Cylex(TM) immuknow assay (in clinical practice and in the clinical re...cus on or include explicit reference to use of the immuknow assay for CMI is as follows: Saturday, May 31,...
ImmuKnow in Medical Technology

Three Independent Studies Include the ImmuKnow(R) Assay to Manage and Optimize Immunosuppression Therapy in Transplant Patients

...ant recipients to determine whether the use of the immuknow assay to guide immunosuppression therapy would red...einer, the lead investigator in this study, "Using immuknow in liver transplant recipients may help minimize r...nagement of immunosuppression therapy was based on immuknow assay levels. In 32 other patients, changes in imm...

Living Donor Kidney Transplants Using Alemtuzumab Pre-Conditioning and Tacrolimus Monotherapy: Long-Term Safety and Efficacy

...antibody titers, donor-specific antibodies and the immuknow assay beginning 6 months posttransplant and at 2-6...ee on tacrolimus monotherapy. The use of the immuknow assay as described in these studies has not been c...U.S. Food & Drug Administration. About immuknow ...

An Independent Study Reports on the Utility of ImmuKnow(R), the Cylex(TM) Immune Cell Function Assay, for Monitoring Heart Transplant Recipients

...have contributed to defining the role of the Cylex immuknow assay among recipients of solid organ transplants....cine followed 337 cardiac transplant patients with immuknow to determine whether immuknow assay values can be correlated with the incidence ...

Cylex Announces Plan for Multi-Center Trial of ImmuKnow(R) Assay in South Korea

...our support for a major, multi-center trial of the immuknow assay for cell-mediated immunity at seven highly r...to be able to demonstrate the effectiveness of the immuknow assay in transplant populations of different ethni...nsortium of kidney transplant centers will use the immuknow assay to assess cell-mediated immunity of 238 pati...

New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation

...ent number of patients to validate the role of the immuknow assay in monitoring risk for organ rejection. The ...y support earlier published data on the use of the immuknow assay in monitoring adult patients after a renal t...ransplant patients, and the potential value of the immuknow assay in monitoring immune status." *Sanchez-Vel...

New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients

...and his colleagues focused on the use of the Cylex immuknow assay to monitor cell-mediated immunity post-trans...ents, cell-mediated immunity as measured using the immuknow assay is classified into three categories, as defi...>12 years of age. -- During clinical quiescence, immuknow assay results correlated with clinical status of t...

University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients

...togen-stimulated peripheral CD4+ T-cells using the immuknow assay has previously be shown to have utility in t...no, "In this study, we wanted to learn whether the immuknow test data correlated with data from other tests an...in terms of levels of ATP, were measured using the immuknow assay and categorized according to the tests label...

Penn State Hershey Transplant Program Uses Assay to Monitor Cell-Mediated Immunity

...urgery at Penn State Hershey Medical Center. The immuknow cell function test measures cell-mediated immunity... 340 ng ATP/ml (within the "moderate" range of the immuknow assay). However, for patients undergoing chemother...f their cancer. "It is clear that we can use the immuknow cell function assay to manage immunosuppression mo...

Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients

...unoreactivity, as measured prospectively using the immuknow assay of CMI, would be different for patients with... preliminary results." "Our study has shown that immuknow values are significantly different for patients wi...suppression to prevent organ rejection. Results of immuknow assays of CMI were included in the analysis if and...

Independent Studies Report on Possible Roles for Cylex's Immune Cell Function Assay in Monitoring of Heart and Lung Transplant Recipients

... Six different studies will report on use of immuknow assay in presentations at the annual meeting of...entations will report on studies of the use of the immuknow assay in a variety of heart and lung transplant re...y, April 11 -- "Success of immune monitoring with immuknow (Cylex) to assess rejection/infectious risk in...
ImmuKnow in Biological Technology

New Independent Research Study Indicates That Cylex's ImmuKnow Test May Identify Kidney Transplant Patients at Risk for Early Acute Rejection

COLUMBIA, Md., Feb. 20 /PRNewswire/ -- Cylex, Inc., today announced the publication of an independent, peer reviewed, clinical research study in which the level of cellular immune response measured prior to kidney transplantation using the Company's proprietary ImmuKnow(R) immune cell function...

Serial Monitoring With ImmuKnow(R) is Useful in the Risk Assessment of Kidney Transplant Recipients

...sity of Miami , evaluated whether single or serial immuknow assessments are most useful in determining rejecti...plant baseline readings and serial monitoring with immuknow are crucial for posttransplant risk assessments. Our results suggest that an isolated immuknow test is insufficient to aid in the management of p...

Cylex(TM) Receives ISO 13485:2003 and 9001:2000 Quality Certifications

...erefore supports the Company's plans to market its immuknow immune cell function assay to customers around the world. About ImmuKnow(R) immuknow is the immune cell function assay cleared by the F...d from CD4 cells following cell stimulation. The immuknow test is a qualitative assay and does not directly ...

Immune Function in Adult Heart Transplant Patients Reflects Risk for Organ Rejection and Infection

...in Boston, MA. "Based on our experience with the immuknow assay we believe it is possible to assess the prob...oring of adult heart transplant patients using the immuknow assay may have the potential to aid in the assessm...n was entitled, "Success of immune monitoring with immuknow (Cylex(TM)) to assess rejection/infectious risk in...

Cylex Announces Brad L. Stewart as President of the Company

...celerate understanding of the value of this technology in specific therapeutic areas. We are also convinced that Cylex can rapidly expand ex-US use of immuknow to support patient care in many other countries. This is an exciting challenge for me personally, and I will have the backing of a talented team of pr...
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