SANCUSO(R), the First and Only Patch for Preventing Nausea and Vomiting in Chemotherapy Patients, Now Available

... contraindicated in patients with known hypersensitivity to granisetron or to any of the components of the patch. Granisetron may mask a progressive ileus and/or gastric distention caused by the underlying condition. Mild application site reactions have occurred; remove patch if severe reactions or a gen...

An unlikely contender for speedy surgery recovery: Chewing gum

...tal one day sooner than the other group. A possible explanation is that chewing gum after surgery can help prevent or reduce postoperative ileus. ileus refers to a condition where the digestive system remains inactive for a period of time post-surgery. Gum chewing stimulates the digestive system, maki...

Ileus in Medical Technology

RAD001 Phase II Trial Results Positive in Patients with Advanced Gastric Cancer After Failure of One or More Prior Treatments

...rade 3 or 4; >3% of patients) included anemia, hyponatremia, raised liver function, fatigue, stomatitis, anorexia, hyperglycemia, hypophosphatemia, ileus and lymphopenia. About RAD 001 RAD001, an oral once-daily inhibitor of mTOR, is an investigational drug being studied in multiple tumor t...

F.D.A. Approves SANCUSO(R), the First and Only Patch for Preventing Nausea and Vomiting in Cancer Patients Undergoing Chemotherapy

... contraindicated in patients with known hypersensitivity to granisetron or to any of the components of the patch. Granisetron may mask a progressive ileus and/or gastric distention caused by the underlying condition. Mild application site reactions have occurred; remove patch if severe reactions or a gen...

New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study

...is developing RELISTOR for the treatment of opioid-induced side effects, including constipation (oral and subcutaneous formulations) and postoperative ileus (intravenous formulation). In the area of HIV infection, the Company is developing the viral-entry inhibitor PRO 140, a humanized monoclonal antibody ...

Wyeth and Progenics Announce Preliminary Clinical Trial Results for RELISTOR Oral and Intravenous Formulations

...avenous formulation of RELISTOR for post-operative ileus (POI). In this study, the drug did not meet its pr...ation of RELISTOR for patients with post-operative ileus (POI) did not meet the primary or secondary end po...utaneous and oral formulations) and post-operative ileus (intravenous formulation). In the U.S., RELISTOR (...

Monogram Biosciences Provides Progenics Pharmaceuticals with HIV Assays for Use in Clinical Trials

...ping methylnaltrexone for the treatment of opioid-induced side effects, including constipation (oral and subcutaneous formulations) and post-operative ileus (intravenous formulation). In March 2007, the Company submitted a New Drug Application to the United States Food and Drug Administration for the subcu...

Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis

...latory Affairs. Tranzyme is developing TZP-101 as a first-in-class gastroprokinetic agent for the treatment of severe gastroparesis and post-operative ileus (POI). Using scintigraphy and a standardized meal, this double blind, randomized, four-way crossover study assessed the efficacy of three different d...

Ileus in Medical Dictionary

Ileus

Ileus is a disruption of the normal propulsive gastrointestinal motor activity from non-mechanical mechanisms . Motility disorders that result from structural abnormalities are termed mechanical bowel obstruction. Some... Ileus commonly occurs for 24 to 72 hours after abdominal surgery,...

Postoperative

...festation of sinus node dysfunction is usually ... Postoperative ileus is a common and potentially serious complication seen in the ... Typically, uncomplicated postoperative ileus will resolve within 5 to 7 days ... Postoperative Care: Book Chapter...

Gallstone

...A gallstone that sticks in the common bile duct obstructs the flow of bile into the duodenum. ... This article aims to review gallstone ileus in the literature addressing the ... Mirizzi syndrome, cholecystocholedochal fistula, and gall- stone ileus. ... Gallstones — Comprehensive o...

Ileus in Biological Technology

Wyeth and Progenics Receive Positive Opinion From European Committee for RELISTOR for the Treatment of Opioid-Induced Constipation in Advanced-Illness Patients

...oping methylnaltrexone for the treatment of opioid-induced side effects, including constipation (oral and subcutaneous formulations) and postoperative ileus (intravenous formulation). In the area of HIV infection, the Company is developing the viral-entry inhibitor PRO 140, a humanized monoclonal antibody ...

ActivBiotics Sells Proprietary Assets, Including Drug Product Candidates

...00 patients/subjects, has an active IND, and a protocol on file with the FDA under which a Phase II clinical trial for the treatment of post-operative ileus can be conducted, and a protocol to initiate a Phase II clinical trial for the treatment of oral mucositis. The Company has submitted and expects to s...