Extensive Clinical Data on Erbitux Presented at the 2007 ASCO
...nfirmed that ERBITUX, an IgGI monoclonal
antibody, induces antibody-dependent cellular cytotoxicity (ADCC)
in contrast to the lack of such activity in igg2
-- Erbitux plus radiation is currently a standard of care for
patients with locally advanced Head and Neck cancer. The Easter...
IgG2 in Biological Products
IgG2 in Biological Definition
...nt activation (classic pathway), opsonization for phagocytosis and neutralisation (immunology) of their toxins. There are 4 subclasses: IgG1 (66%), igg2
(23%), IgG3 (7%) and IgG4 (4%).
IgA represent about 15 to 20% of immunoglobulins in the blood although it is primarily secreted across the ...