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IgA in Medical News

BioMarin Announces Second Quarter 2009 Financial Results

...tnering options for this program. BMN-185 - iga protease for iga nephropathy: BioMarin is completing early preclin...e continuation of the program by the end of 2009. iga proteases have been shown to cleave...

HHS Secretary Sebelius Highlights Michigan's MHA Keystone Center in Inaugural Health Care 'Success Story' Report

...se good exam ples across the country," said Sebelius. "Our reports will showcase succe s s stories like the Mic h iga n Keystone ICU Project and highlight how health reform can improve the quality of care for all Americans." "When we enact ...

How to confirm the causes of iron deficiency anemia in young women

...isease with the use of two tests (human recombinant tissue transglutaminase iga antibodies and anti- H. pylori IgG antibodies) in women aged In this s...mples and widely available tests, such as those for tissue transglutaminase iga antibodies and anti- H. pylori IgG antibodies, were able to select women w...

BioRay's CytoFlora Reduces Digestive and Behavioral Issues in Autistic Children

... One May 22 - 25, 2009 CytoFlora decreases iga and IgM antibodies to intestinal bacteria in child...system response. Baseline results showed elevated iga and IgM levels, signifying an immune response to b...pletion results revealed a 55% overall decrease in iga levels and a 27% decrease in IgM levels. Parents...

Landmark Rh Immune Globulin Celebrates 40 Years of Saving Babies' Lives

...AM(R) and MICRhoGAM(R) contain a small quantity of iga and physicians must weigh the benefit against the .... There is a potential risk of hypersensitivity in iga deficient individuals. Patients treated fo... RhoGAM and MICRhoGAM contain a small quantity of iga (less than 15 micro grams per dose). Although high...

Nose-spray vaccine against botulism effective in first tests

...in, another name for antibody, and the specific response to vaccine in the current study consisted of IgG, IgG1, and IgG2a activation in the blood and iga activation in mucous membranes. In mice injected with lethal doses of BoNT/C toxin, all mice (8/8, or 100 percent) that received larger dose (2 10...

NIDDK publishes new resources about urologic and kidney disorders

... tract infections (UTIs) in children, prostatitis, iga nephropathy, and home hemodialysis. What I ....niddk.nih.gov/kudiseases/pubs/prostatitis . iga Nephropathy. This fact sheet explains iga nephropathy, a kidney disorder that occurs when Ig...

'Study Shows Mothers Who Take Chlorella Boost Babies' Antibodies During Breast Feeding'

...plements during pregnancy had significantly higher iga antibody concentrations in their breast milk(1). The higher levels of iga resulted in a reduced risk of infection in nursing..., IgM, IgE, and IgD. All are found in breast milk. iga antibodies protect body surfaces that are exposed ...

JCI online early table of contents: Jan. 2, 2008

...IgA1 is prematurely sialylated in individuals with iga nephropathy Among individuals with the relatively common kidney disease iga nephropathy, 2040% go on to develop end-stage kidn...l lines from the peripheral blood of patients with iga nephropathy and demonstrated that premature sialyl...

Gene responsible for immune deficiency discovered

..., and help clinical practitioners identify problems at an early stage. This will be boon for most sick children because they can have normal levels of iga and IgG, and have poor antibody responses, that make their condition difficult to diagnose. Reference: Nature Genetics, July 2005...

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IgA in Medical Technology

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

Trial to Evaluate Safety of CCL2-LPM for Inflammatory Kidney Disease SAN FRANCISCO, April 14 /PRNewswire/ -- Osprey Pharmaceuticals U.S.A., Inc. announced today that patient dosing has commenced in a Phase Ib clinical trial of the company's lead compound, CCL2-LPM, for the treatment of IgA ne...

Mymetics' HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model

NYON, Switzerland, June 07, 2007 /PRNewswire-FirstCall/ -- Mymetics Corporation announced today analysis of results demonstrating that the Company's HIV vaccine elicited neutralizing IgA mucosal antibodies in a non-human primate model. Mucosal IgA antibodies are considered as a possible first line...

Baxter Initiates Phase III Trial for the Treatment of Alzheimer's Disease

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) p...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

...e Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA a...elective IgA deficiency (IgA < 0.05 g/L) where the iga deficiency is the only abnormality of concern. I...ctions or anaphylaxis in the setting of detectable iga levels following infusion of GAMMAGARD S/D. Immu...

Baxter Presents Latest Clinical Trial Results of GAMMAGARD LIQUID Administered Subcutaneously

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) p...

Cutanea Announces Promising Phase II Results in Rosacea with Omiganan

...s at Week nine and at each interim visit, the percent change in number of inflammatory lesions at interim visits, the absolute change from Baseline in iga score and other signs and symptoms of rosacea at Week nine and each interim visit, and Treatment Success at Week nine and each interim visit. Althoug...

Baxter and The Alzheimer's Disease Cooperative Study Group to Pursue a Phase III Study of Gammagard Liquid in Patients With Alzheimer's Disease

...e Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA a...selective IgA deficiency (IgA, 0.05 g/L) where the iga deficiency is the only abnormality of concern. Im...ctions or anaphylaxis in the setting of detectable iga levels following infusion of GAMMAGARD S/D. Immun...

Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers' Diarrhea Patch Vaccine

...i patch, regardless of age, seroconverted with IgG antibodies. Moreover, 18 of 19 elderly subjects and 15 of 17 adult subjects also seroconverted with iga antibodies. The study was conducted in Belfast, Ireland, and subjects received two patches, 21 days apart, containing "heat labile" toxin, or LT, and ...

Mymetics' HIV Vaccine Achieves Research Breakthrough, Eliciting Protective Antibody Response in Mucosal Tissues of Non-Human Primate Model

...nced today that the Company's HIV vaccine elicited iga mucosal antibodies in a non-human primate model. Mucosal iga antibodies are considered a possible first line of...eptides from the MPR can Elicit Protective Mucosal iga in Vaccinated Macaques," at the Keystone Symposium...

Ceragenix Announces Results from Phase IV Study of EpiCeram Meet All Primary and Secondary Endpoints

... Percentage of subjects reaching clear or almost clear on IGA at Day 28 Assessment of the disease progression showed significant improvements in the iga scores over time for both EpiCeram(TM) and Cutivate(R) cream with 61.1% of the EpiCeram(TM) patients assessed as clear or almost clear after 28 days o...

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IgA in Medical Products

Goat Anti-Human IgA Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Goat anti-human IgA (Alpha Chain) - 12 OD...
Company:BioAssay Works, L.L.C.

Yersinia Species Antibody, IgA by Western Blot

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Yersinia Species Antibodies, IgA & IgG by Western Blot

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Yersinia IgA & IgG by Western Blot

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Yersinia IgA by Western Blot

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Tissue Transglutaminase Antibody, IgA with Reflex to Endomysial Antibody, IgA Titer by IFA

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Rheumatoid Factor, IgM, IgG, & IgA by EIA

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Reticulin Antibody, IgA with Reflex to Titer

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Pemphigus IgA Antibodies

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Linear IgA Bullous, Tissue

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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IgA in Biological News

UT pathologists believe they have pinpointed Achilles heel of HIV

...re able to fragment it and destroy its function. Their recent work indicates that naturally occurring catalytic antibodies, particularly those of the iga subtype, may be useful in the treatment and prevention of HIV infection," said Steven J. Norris, Ph.D., holder of the Robert Greer Professorship in th...

UAB microbiologist wins top Czech science honor

...which in later years turned out to be a first step toward convincing many scientists that the mouth is integral to mucosal immunity, Mestecky said. iga researchers like Mestecky continue to break ground on a better understanding and new treatment options for deadly conditions like kidney failure, myel...

Biologists Crack Genetic Code for Specialized Spider Silk

...sts to detect the two disorders. A deficiency of iga ?an important type of infection-fighting antibody ...cells, cells that produce antibodies. Furthermore, iga deficiency and CVID can predispose to autoimmune d...own tissues and organs. “Most cases of CVID and iga deficiency are of unknown cause,?notes Josiah Wedg...

Agreement will speed research on microbicides for women

...sts to detect the two disorders. A deficiency of iga ?an important type of infection-fighting antibody ...cells, cells that produce antibodies. Furthermore, iga deficiency and CVID can predispose to autoimmune d...own tissues and organs. “Most cases of CVID and iga deficiency are of unknown cause,?notes Josiah Wedg...

Defective Gene Linked to Two Inherited Immune Deficiencies

...sts to detect the two disorders. A deficiency of iga ?an important type of infection-fighting antibody ...cells, cells that produce antibodies. Furthermore, iga deficiency and CVID can predispose to autoimmune d...own tissues and organs. “Most cases of CVID and iga deficiency are of unknown cause,?notes Josiah Wedg...

Protein amplification in melanoma is possible drug target

...go unrecognized because of a lack of good tests. iga deficiency affects 1 in 600 people; CVID is less c...hitis, pneumonias and gastrointestinal infections. iga deficiency and CVID can occur in the same family, ...s with CVID and in 1 of 16 unrelated patients with iga deficiency. None of 50 healthy people tested had a...

Gene for immune deficiency syndromes found

...go unrecognized because of a lack of good tests. iga deficiency affects 1 in 600 people; CVID is less c...hitis, pneumonias and gastrointestinal infections. iga deficiency and CVID can occur in the same family, ...s with CVID and in 1 of 16 unrelated patients with iga deficiency. None of 50 healthy people tested had a...

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IgA in Biological Technology

BioMarin and IGAN Biosciences to Collaborate on Development of an Enzyme Therapy to Treat IgA Nephropathy, a Rare and Life-Threatening Kidney Disease

NOVATO, Calif., Dec. 3 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq and SWX: BMRN) and IGAN Biosciences announced today that they have initiated a program to develop an IgA protease for treating IgA nephropathy. IgA proteases have been shown to cleave IgA complexes, the depos...

BioMarin Announces First Quarter 2009 Financial Results

...velopment by the end of 2009. BMN-185 - iga protease for iga nephropathy: BioMarin is completing lead optimiza...n continuation of the program by the end of 2009. iga proteases have been shown to cleave...

Pharmalink AB Completes Phase II Clinical Study With Renal Disease Drug Nefecon(R)

...valuating the efficacy and safety of Nefecon(R) in iga nephropathy, a glomerulonephritis leading to end-s...ephropathy Patients) and at the satellite meeting, iga Nephropathy, 26-28 May in Stresa, Italy. "I...t-licensing: Nefecon(R), an effective treatment of iga nephropathy; Xepol(R), the first effective treatme...

Pharmalink AB Strengthens its Board of Directors and Signals a Strategic Step Towards Late Phase Product Development

...products to market. Pharmalink currently has three clinical phase development projects mature for out-licensing: Nefecon(R), an effective treatment of iga nephropathy; Xepol(R), the first effective treatment of neurology indication post-polio syndrome; and Busulipo(TM), a safer alternative for myeloablat...

Phase III Trial Begins for GAMMAGARD LIQUID Plus rHuPH20 in Primary Immunodeficiency Patients

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (...

Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) p...

Baxter and Halozyme Announce Collaboration for Development of Subcutaneous GAMMAGARD LIQUID(TM) Administration Using Enhanze(TM) Technology

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) pr...

Baxter to Launch GARDian(TM), a Groundbreaking Initiative That Helps Provide Continued Access to GAMMAGARD for Current Patients

...selective IgA deficiency (IgA, 0.05 g/L) where the iga deficiency is the only abnormality of concern. About GAMMAGARD S/D with iga GAMMAGARD S/D is indicated for the treatment of ...elective IgA deficiency (IgA < 0.05 g/L) where the iga deficiency is the only abnormality of concern. Ab...

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IgA in Biological Products

Toxoplasma IgA ELISA Kit, Single from Bio-Quant Inc.

Description: Request Info...
Company:Bio-Quant Inc.

H. Pylori IgA ELISA Kit, Single from Bio-Quant Inc.

Description: Request Info...
Company:Bio-Quant Inc.

Chlamydia pneumonia IgA ELISA Kit, Single from Bio-Quant Inc.

Description: Request Info...
Company:Bio-Quant Inc.

EBV-VCA IgA ELISA Kit, Single from Bio-Quant Inc.

Description: Request Info...
Company:Bio-Quant Inc.

Chlamydia trachomatis IgA ELISA Kit, Single from Bio-Quant Inc.

Description: Request Info...
Company:Bio-Quant Inc.

Cat IgA ELISA Kit from Bethyl Laboratories

Description: Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Company:Bethyl Laboratories

Tissue Trans-glutaminase-directed IgA EIA Kit from Alpco Diagnostics

Description: Anti-Tissue Trans-glutaminase (IgA) EIA Sample Size: 10 l...
Company:Alpco Diagnostics

Ps-Aeruginosa-directed IgA EIA Kit from Alpco Diagnostics

Description: Ps-Aeruginosa (IgA) -Ab EIA Sample Size: 100 l...
Company:Alpco Diagnostics

Candida-directed IgA EIA Kit from Alpco Diagnostics

Description: Candida (IgA) -Ab EIA Sample Size: 5 l...
Company:Alpco Diagnostics

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IgA in Biological Definition

Antibody

...the antibody 3 Isotypes 3.1 IgG 3.2 iga 3.3 IgM 3.4 IgD 3.5 IgE 4 Functio...are grouped into five classes or isotypes: IgG , iga , IgM , IgD , and IgE . (The isotypes are also ...1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). iga ...
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