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INR in Medical News

New Immune Approach for Treatment of Alzheimer's Disease

...ncept of these novel methods which Dr. Tobinick invented (8, 9), which include both perispinal and epidural etanercept for treatment of sciatica (see inr sciatica website ) (8), are now supported by additional, independent studies from academic centers, including a new randomized, double-blind, placebo-...

AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances

...azole, of which NEXIUM is an enantiomer. As with all PPIs, patients treated concomitantly with warfarin may need to be monitored for increases in inr and prothrombin time. Like other proton pump inhibitors, esomeprazole may interfere with the absorption of drugs where gastric pH is an important dete...

Research Validates Safety of Dawn AC Anticoagulation Management Software

... thrombosis were almost identical. ·   Therapeutic inr control improved from 63.4 percent with manual dosage to 66.8 percent with ... the two legs of the trial was statistically highly significant in terms of inr control. "The results should reassure hospitals and community clin...

Twenty New Abstracts on Oral Xeloda(R) (capecitabine) Featured at the 31st San Antonio Breast Cancer Symposium

...een reported. Clinically significant increases in prothrombin time (PT) and inr have been observed within days to months after starting Xeloda, and infrequ...a. For patients receiving both drugs concomitantly, frequent monitoring of inr or PT is recommended. Age greater than 60 and a diagnosis of cancer indepe...

Excellence in Supply Chain and Manufacturing Recognized at Frost & Sullivan's India Manufacturing Excellence Awards 2008

...lip Oommen, CEO, Essar Steel (India). IMEA 2008 saw both Large and Emerging Enterprises (defined as SMEs or companies with turnover less than inr 100 Crore) presented the Corporate Platinum Award and Corporate Gold Award across sectors such as Automotive, Automotive Ancillaries, Engineering,...

Research highlights new approaches to prevent blood clots

... four fixed-dose regimens of DU-176b (30 mg once-daily, 30 mg twice-daily, 60 mg once-daily, 60 mg twice-daily) or warfarin (dose-adjusted to a target inr of 2.0 to 3.0) for 12 weeks. The primary endpoints of the study were the incidence of bleeding events (major and clinically relevant non-major) and el...

New Drug May Help Combat Alzheimer's

... For a further description of the attached video, please see the Medscape J Med. 2008; 10(6): 135. Physician training is available; please contact the inr for further information. The new articles are open access, and available directly at the following links: http://www.medscape.com/viewarticl...

Computers as safe as medical experts in prescribing blood thinning drugs

...easured as the 'international normalised ratio' or inr resulted in clinical benefit and improved safety...., at prescribing the correct dosage to prolong the inr in patients as dosages given by expert medical pro...e than 13,000 patients. It analysed nearly 400,000 inr tests, divided evenly between manual and computer-...

Xeloda(R), Taxotere(R) and Herceptin(R) Combination Study Suggests Clinical Benefit in Invasive Breast Cancer with Shortened Treatment Cycle

...een reported. Clinically significant increases in prothrombin time (PT) and inr have been observed within days to months after starting Xeloda, and infrequ...da. For patients receiving both drugs concomitantly, frequent monitoring of inr or PT is recommended. Age greater than 60 and a diagnosis of cancer indepen...

Cipla Offers Modest AIDS Drug Price Cut: 'Not Nearly Enough,' says AHF

...red in both Indian rupees and US dollars: Cipla Drug Old Price inr (US $) New Price inr (US $) Viraday 54000 (US $1341) 46800 (US $1163) ...
INR in Medical Technology

Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing

...80 administered twice daily), or warfarin (N=250) dose-adjusted locally to a target International Normalized Ratio (INR) of 2.0-3.0 for 12 weeks. The inr was determined weekly for four weeks and every two weeks thereafter. Investigators, sponsors and study subjects were blinded to the edoxaban dose; ho...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

...azole, of which NEXIUM is an enantiomer. As with all PPIs, patients treated concomitantly with warfarin may need to be monitored for increases in inr and prothrombin time. Like other proton pump inhibitors, esomeprazole may interfere with the absorption of drugs where gastric pH is an important dete...

New Overall Survival Study Results Confirm Oral Xeloda(R) plus Oxaliplatin (XELOX) is Comparable to FOLFOX-4 for the First-Line Treatment of Advanced Colorectal Cancer

...een reported. Clinically significant increases in prothrombin time (PT) and inr have been observed within days to months after starting Xeloda, and infrequ...a. For patients receiving both drugs concomitantly, frequent monitoring of inr or PT is recommended. Age greater than 60 and a diagnosis of cancer indepe...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

...four fixed-dose regimens of DU-176b (30 mg once-daily, 30 mg twice-daily, 60 mg once-daily, 60 mg twice- daily) or warfarin (dose-adjusted to a target inr of 2.0 to 3.0) for 12 weeks. The primary endpoints of the study were the incidence of bleeding events (major and clinically relevant non-major) and el...

New Phase II Data Show Safety of Once-Daily Oral Factor Xa Inhibitor, DU-176b, Comparable to Warfarin in Patients With Non-Valvular Atrial Fibrillation

...80 administered twice daily), or warfarin (N=250) dose-adjusted locally to a target International Normalized Ratio (INR) of 2.0-3.0 for 12 weeks. The inr was determined weekly for four weeks and every two weeks thereafter. Investigators, sponsors and study subjects were blinded to the DU-176b dose; howe...

Pharmacyclics Announces Completion of Phase 1 Clinical Trial of Factor VIIa Inhibitor PCI-27483

...rognosis." In the recently completed study, PCI-27483 increased the inr with minimal intra-subject variation and a half-life of ten hours. At the h...doses of PCI-27483, which upon repeated dosing are expected to maintain the inr in the range of 2.0 to 3.0, the target window for treatment and prevention ...

AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication

...eprazole, of which NEXIUM is an enantiomer. As with all PPIs, patients treated concomitantly with warfarin may need to be monitored for increases in inr and prothrombin time. Like other proton pump inhibitors, esomeprazole may interfere with the absorption of drugs where gastric pH is an important dete...

Nearly 60 New Studies of Oral Xeloda(R) (capecitabine) Featured at the 44th American Society of Clinical Oncology Annual Meeting

...een reported. Clinically significant increases in prothrombin time (PT) and inr have been observed within days to months after starting Xeloda, and infrequ...da. For patients receiving both drugs concomitantly, frequent monitoring of inr or PT is recommended. Age greater than 60 and a diagnosis of cancer indepen...

Novel Xeloda(R) Dosing Schedule May Offer Well-Tolerated Alternative for Treatment of Advanced Breast Cancer

...een reported. Clinically significant increases in prothrombin time (PT) and inr have been observed within days to months after starting Xeloda, and infrequ...da. For patients receiving both drugs concomitantly, frequent monitoring of inr or PT is recommended. Age greater than 60 and a diagnosis of cancer indepen...

Medicare Announces Expanded Coverage for Anticoagulation Patients, Opening the Door for More Patients to Test PT/INR at Home

...han C., Alonso-Coello P, Garcia-Alamino JM, Perera R, Meats E, Glasziou P. Lancet. 2006; 367:404-411. (2) Kortke H, Minami K, Breymann T, et al. inr self-management after mechanical heart valve replacement: ESCAT. Z Kardiol. 2001;90(6)118- 124. (3) Oral Anticoagulation Group. American Jo...
INR in Medical Products

CoaguChek XS

Description:...low-up system to the proven CoaguChek S system. It encompasses several innovative technical developments which offer more security and confidence with inr results....
Company:Roche Diagnostics

Immedia PT System

Description:... The Immedia PT System is an in vitro diagnostic device that provides quantitative prothrombin time (PT) results, expressed in seconds and inr units. The System uses fresh capillary whole blood. It is intended for use by health care professionals at the point of care to monitor patients who a...
Company:Farallon Medical, Inc.

HEMOCHRON Response Coagulation Monitoring Instrument

Features:... Results displayed as whole blood, plasma equivalent, or inr for PT assay only Store 600 patient tests per well Store Operator and Patient Identification Allows supervisor to create and lock OID table ...
Company:ITC
INR in Biological News

American College of Medical Genetics responds to new FDA labeling decision for warfarin

...ypes can reasonably be used as part of diagnostic efforts to determine the cause of an unusually low maintenance dose of warfarin or an unusually high inr (the test used to monitor warfarin) during standard dosing, said Michael S. Watson, PhD, FACMG, Executive Director of the American College of Medical ...

Genetics determine optimal drug dose of common anticoagulant

... For the first time, a group of St. Louis researchers combined the standard inr method with genetic testing to predict the therapeutic warfarin dose. Since...d several weeks later. By combining variants in these genes with initial inr response and other clinical factors, the researchers derived a dosing equat...
INR in Biological Technology

Growing Awareness and Increased Investments Lead to Growth of Biotechnology Applications in the Food & Beverage and Dietary Supplements Sector, Reveals Frost & Sullivan

...Omega-3 PUFA for food and dietary supplement applications were an estimated inr 40 Crore. Supplement applications command the major market share with over ...s technology so powerful. The total Indian F&B enzymes market was worth inr 88 Crore in 2008. The market grew at 11 percent from 2007 to 2008. The mark...

New 200 mg Vial for Eloxatin(R) (Oxaliplatin Injection) Offers Greater Convenience and Efficiency of Preparation

...is. Injection site reaction, including redness, swelling and pain, has been reported -- There have been reports of prolonged prothrombin time and inr occasionally associated with hemorrhage in patients receiving Eloxatin(R) plus 5-FU/LV while on anticoagulants. Patients receiving Eloxati...
INR in Biological Definition

Blood plasma

...sit between the liquid and cellular layers in the tube after centrifugation, making separation more convenient. Tests of coagulation (such as the inr and APTT ) require all clotting factors to be preserved. Serum, therefore, is inappropriate for these tests. A citrated evacuated blood collection t...
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