Navigation Links
IKK in Medical News

Instead of fighting breast cancer, immune cell promotes its spread

... by activating cells that help break down bone. Along with another protein, ikk alpha, it has been implicated both in tumor formation and metastasis. Th... Tan noted that additional experiments showed that blocking both RANKL and ikk alpha in those breast tumor cells inhibited lung metastases. "More importan...

Oncoproteins double-team and destroy vital tumor-suppressor

...r had an average volume of more than 600 cubic millimeters. ERK, AKT and ikk are three separate cancer-causing kinases - proteins that phosphorylate oth...of human cancers." "Pharmaceutical companies work to target ERK, AKT and ikk separately," Hung notes. "But activating their forkhead target would work a...

Pathway links inflammation, angiogenesis and breast cancer

...a, a protein kinase activated by TNFa," Hung says. ikk inactivates a cancer-suppressing protein complex, ... colleagues works like this: TNFa activates ikk , which as a kinase works by attaching phosphate groups to other proteins. ikk phosphorylates tuberous sclerosis 1 (TSC1) blockin...

Repeated Liver Cell Proliferation, a Cause for Liver Cancer

... colleagues strongly suggest that the control of tissue renewal through the ikk and JNK pathways plays a key role in liver cancer in mouse models. One ... 2005, Karin and his colleagues at UCSD implicated the pathway's activator, ikk , in chemically induced liver cancer. However, the surprising outcome of th...

TNF Helps in the Understanding of the Immune System and Development of Drugs against Various Ills

...NF's warning message travels from the surface of a cell to its nucleus a molecule called Inhibitor of KappaB Kinase (IKK) plays a very important role. ikk carefully controls the level of the immune system's response. Hence by altering this molecule one can develop new medications designed to boost or sup...
IKK in Medical Technology

Nereus Pharmaceuticals to Present Data at the American Association for Cancer Research 2007 Annual Meeting

...nd a new preclinical candidate NPI-1387, a highly selective, small molecule ikk modulator. Nereus will also present preliminary data from its Phase I dose ... has a family of over 400 synthetic small molecule diterpenes that modulate ikk and many downstream cytokines including TNF-alpha, IL-6, IL-8 and others. T...
IKK in Biological News

NCI renewal grant to develop new cancer therapies

...ion as a platform to develop novel combination regimens incorporating histone deacetylase inhibitors and NF-kappa B antagonists such as proteasome and ikk beta inhibitors in the treatment of acute leukemia and other hematologic malignancies." Grant and his team are already leading a multi-institutio...

Cycles of cell death, proliferation key to liver cancer

... colleagues strongly suggest that the control of tissue renewal through the ikk and JNK pathways plays a key role in liver cancer in mouse models. One l... 2005, Karin and his colleagues at UCSD implicated the pathway's activator, ikk , in chemically induced liver cancer. However, the surprising outcome of t...

Protein finding could lead to treatment for inflammatory diseases

...appa Kinase (IKK) complex. The normal function of ikk is to trigger the degradation of a protein that in...bits NF-kB activity. MC160 subsequently causes the ikk complex to fall apart to prevent the phosphorylati...y, than any identified before, by focusing on this ikk complex." Shisler has obtained a patent to purs...

Infection 'alarm' yields clues to immune system behavior

...arefully controls the level of the immune system's response." That makes ikk a very promising target for new medications designed to boost or suppress t...erized by a weak inflammatory response might be helped by a drug that makes ikk even more sensitive to infection messages. The researchers believe their...

Firefly protein lets researchers monitor molecule linked to cancer

...l other disorders. The target molecule, known as ikk (for IKappa kinase), regulates processes that can ...t from the firefly protein, luciferase, to monitor ikk activity in tumor cells and inflamed liver cells i...ear in the August 2005 issue of Nature Methods. ikk stands at a pivot point in the middle of an import...
Other Tags
(Date:9/1/2014)... More than 200 Lipitor lawsuit ( http://www.thelipitorlawsuit.com/ ... that continues to progress in the U.S. District Court, ... , A federal Case List published on August 15th ... medication by plaintiffs who developed Type 2 diabetes allegedly ... failed to adequately warn patients and their doctors about ...
(Date:9/1/2014)... HealthDay Reporter FRIDAY, Aug. 29, 2014 (HealthDay ... American aid workers successfully cured a group of monkeys infected ... The drug, ZMapp, prompted recovery in all 18 monkeys who ... five days after infection. ZMapp even cured monkeys with ... away from death, said study senior author Gary Kobinger, chief ...
(Date:9/1/2014)... (PRWEB) September 01, 2014 As well ... training, Derek is currently pursuing counselor certification in Louisiana. ... advance through the CPI training program as well as ... I have grown both personally and professionally. I ... I am competently able to do so. As ...
(Date:9/1/2014)... York (PRWEB) September 01, 2014 ... retrieve, organize and analyze biological and genetic data. ... the activity of developing software tools to generate ... to be confused with biological computation. While bioinformatics ... understanding of biology can its related concepts, biological ...
(Date:9/1/2014)... Secaucus, NJ (PRWEB) September 01, 2014 Registration ... For The Warriors® 5K and 1-Mile Race to be held ... at The Plaza Court Yard at Harmon Meadow in Secaucus, ... For The Warriors®, a national nonprofit dedicated to restoring a ... for our service members and our military families. , General ...
Breaking Medicine News(10 mins):Health News:South Carolina Litigation Adds 200 Lipitor Lawsuits in a Month, as Plaintiffs File Suits Alleging New-Onset Diabetes, Bernstein Liebhard LLP Reports 2Health News:South Carolina Litigation Adds 200 Lipitor Lawsuits in a Month, as Plaintiffs File Suits Alleging New-Onset Diabetes, Bernstein Liebhard LLP Reports 3Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 2Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 3Health News:Narconon Louisiana Announces New Certifications For Staff 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 3Health News:Bioinformatics Market: A fusion of Computers and Biological Data 4Health News:Hope For The Warriors New Jersey Run to Honor Wounded and Families of the Fallen 2
(Date:9/1/2014)... increasing amount of research shows an association between TV ... lifestyle. Now, a new Cornell University study points out ... might lead people to eat twice as much as ... action movie while snacking your mouth will see more ... the new article just published in the Journal ...
(Date:9/1/2014)... quality in the U.S. has improved steadily in recent ... overall dietary quality remains poor and disparities continue to ... new study from Harvard School of Public Health (HSPH). ... date that the extensive efforts by many groups and ... payoff, but it also indicates that these efforts need ...
(Date:9/1/2014)... the U.S. diet showed some modest improvement in the ... in the consumption of unhealthy trans fats, but the ... and the poor. , , An unhealthy diet is ... Eating a healthy diet is an important part of ... trends in diet quality is important because it can ...
Breaking Biology News(10 mins):Can action movies make you fat? 2Quality of US diet shows modest improvement, but overall remains poor 2Quality of US diet shows modest improvement, but overall remains poor 3Quality of US diet improves, gap widens for quality between rich and poor 2Quality of US diet improves, gap widens for quality between rich and poor 3
Other Contents