Navigation Links
IKK in Medical News

Instead of fighting breast cancer, immune cell promotes its spread

... by activating cells that help break down bone. Along with another protein, ikk alpha, it has been implicated both in tumor formation and metastasis. Th... Tan noted that additional experiments showed that blocking both RANKL and ikk alpha in those breast tumor cells inhibited lung metastases. "More importan...

Oncoproteins double-team and destroy vital tumor-suppressor

...r had an average volume of more than 600 cubic millimeters. ERK, AKT and ikk are three separate cancer-causing kinases - proteins that phosphorylate oth...of human cancers." "Pharmaceutical companies work to target ERK, AKT and ikk separately," Hung notes. "But activating their forkhead target would work a...

Pathway links inflammation, angiogenesis and breast cancer

...a, a protein kinase activated by TNFa," Hung says. ikk inactivates a cancer-suppressing protein complex, ... colleagues works like this: TNFa activates ikk , which as a kinase works by attaching phosphate groups to other proteins. ikk phosphorylates tuberous sclerosis 1 (TSC1) blockin...

Repeated Liver Cell Proliferation, a Cause for Liver Cancer

... colleagues strongly suggest that the control of tissue renewal through the ikk and JNK pathways plays a key role in liver cancer in mouse models. One ... 2005, Karin and his colleagues at UCSD implicated the pathway's activator, ikk , in chemically induced liver cancer. However, the surprising outcome of th...

TNF Helps in the Understanding of the Immune System and Development of Drugs against Various Ills

...NF's warning message travels from the surface of a cell to its nucleus a molecule called Inhibitor of KappaB Kinase (IKK) plays a very important role. ikk carefully controls the level of the immune system's response. Hence by altering this molecule one can develop new medications designed to boost or sup...
IKK in Medical Technology

Nereus Pharmaceuticals to Present Data at the American Association for Cancer Research 2007 Annual Meeting

...nd a new preclinical candidate NPI-1387, a highly selective, small molecule ikk modulator. Nereus will also present preliminary data from its Phase I dose ... has a family of over 400 synthetic small molecule diterpenes that modulate ikk and many downstream cytokines including TNF-alpha, IL-6, IL-8 and others. T...
IKK in Biological News

NCI renewal grant to develop new cancer therapies

...ion as a platform to develop novel combination regimens incorporating histone deacetylase inhibitors and NF-kappa B antagonists such as proteasome and ikk beta inhibitors in the treatment of acute leukemia and other hematologic malignancies." Grant and his team are already leading a multi-institutio...

Cycles of cell death, proliferation key to liver cancer

... colleagues strongly suggest that the control of tissue renewal through the ikk and JNK pathways plays a key role in liver cancer in mouse models. One l... 2005, Karin and his colleagues at UCSD implicated the pathway's activator, ikk , in chemically induced liver cancer. However, the surprising outcome of t...

Protein finding could lead to treatment for inflammatory diseases

...appa Kinase (IKK) complex. The normal function of ikk is to trigger the degradation of a protein that in...bits NF-kB activity. MC160 subsequently causes the ikk complex to fall apart to prevent the phosphorylati...y, than any identified before, by focusing on this ikk complex." Shisler has obtained a patent to purs...

Infection 'alarm' yields clues to immune system behavior

...arefully controls the level of the immune system's response." That makes ikk a very promising target for new medications designed to boost or suppress t...erized by a weak inflammatory response might be helped by a drug that makes ikk even more sensitive to infection messages. The researchers believe their...

Firefly protein lets researchers monitor molecule linked to cancer

...l other disorders. The target molecule, known as ikk (for IKappa kinase), regulates processes that can ...t from the firefly protein, luciferase, to monitor ikk activity in tumor cells and inflamed liver cells i...ear in the August 2005 issue of Nature Methods. ikk stands at a pivot point in the middle of an import...
Other Tags
(Date:7/11/2014)... WWTrek Human Outreach Project Team ... in Tanzania. Opened in 2012, the KKC is now home ... HOP Founder, Dean Cardinale, started the KKC to create a ... children he encountered while running treks on Tanzania's Mount Kilimanjaro. ... have all made astounding progress in school over the three ...
(Date:7/11/2014)... prescribed exercise as medicine, according to a QUT ... is essential to reducing the risk of death ... QUT,s Institute of Health and Biomedical Innovation, said ... and mental health, health professionals should be prescribing ... Anderson and QUT,s Dr Charlotte Seib co-authored a ...
(Date:7/11/2014)... Emily Johnson, owner of the Portland Fit Body Boot ... camp has held two charity workout events and is about ... from 7:15 - 8:30 at Col Summers City Park, SE 20th ... session raised $510 for Medical Teams International. Their second workout event ... Dream. On July 26th, Johnson and Portland Fit Body Boot ...
(Date:7/11/2014)... CO (PRWEB) July 11, 2014 H.E.A.R ... A new organization launches this week to provide comprehensive ... Reaching almost half a million Coloradoans with hearing ... to provide all encompassing information of the local and ... the deaf and hearing impaired. , H.E.A.R. Me Out ...
(Date:7/11/2014)... Leeds, England (PRWEB) July 11, 2014 Having ... later as a member of mental hospital staff, Roger Grainger ... among medical professionals in his new book, “You Never Get ... 4 people in the United Kingdom will experience some kind ... , “Society still needs to take a look at ...
Breaking Medicine News(10 mins):Health News:Human Outreach Project Sees Incredible Progress in the Kilimanjaro Kids Community 2Health News:Exercise is the best medicine: QUT study 2Health News:Portland Fit Body Boot Camp Invites Public to Fitness Boot Camp Session Benefiting Children’s Cancer Association 2Health News:Portland Fit Body Boot Camp Invites Public to Fitness Boot Camp Session Benefiting Children’s Cancer Association 3Health News:H.E.A.R Me Out Listens to Needs of Hearing Impaired 2Health News:H.E.A.R Me Out Listens to Needs of Hearing Impaired 3Health News:Psychiatric Hospital Patient and Registered Psychologist Explores Mental Health and Therapy in New Book "You Never Get Out" 2
(Date:7/10/2014)... , June 27, 2014  The American Academy ... Institute of Standards and Technology (NIST) and the ... academic research and forensic science expert members to ... is an element of the NIST,s Organization of ... among the first appointments made to the new ...
(Date:7/10/2014)... 2014 Smart technology emphasis grows in ... improved security: NXT-ID, Inc. (OTCBB: NXTD), eBay Inc. (NASDAQ: ... Apple Inc. (NASDAQ: AAPL ), Visa Inc. (NYSE: ... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused on ... second series of 30 second spots on CNBC for its ...
(Date:7/10/2014)... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused on the growing ... was interviewed on July 1 st on the Downtown ... Mr. Pereira discusses the company,s next generation smart wallet with ... Wocket™ aims to replace a traditional wallet with a new ... tells Gino he has never heard of the Wocket and ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 4
Other Contents