IIa

InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early

OXFORD, England, May 18 /PRNewswire/ -- PharmaVentures Ltd, announced today that it has been engaged by InDex Pharmaceuticals AB to advise and assist in out-licensing its first in class therapeutic, Kappaproct (DIMS 0150), for the treatment of steroid resistant / dependent Inflammatory Bowel Disea...

Arete Therapeutics Initiates Phase IIa Clinical Trial for AR9281, a Novel s-EH Inhibitor to Treat Type 2 Diabetes

HAYWARD, Calif., Feb. 10 /PRNewswire/ -- Arete Therapeutics Inc. today announced the initiation of a Phase IIa clinical trial for AR9281, an orally- administered soluble epoxide hydrolase (s-EH) inhibitor being developed for the treatment of type 2 diabetes. S-EH is an enzyme involved in the m...

MDS Announces Strategy to Focus MDS Pharma Services on Early Stage Operations - Discovery Through Phase IIa

Company to Divest Late Stage Operations, Signs Agreement to Sell Phase II-IV Operations to INC Research TORONTO, June 1 /PRNewswire-FirstCall/ - MDS Inc. (TSX: MDS; NYSE: MDZ ), a leading provider of products and services to the global life sciences markets, today announced that i...

Maxygen Initiates Phase IIa Clinical Trial of MAXY-G34 in Breast Cancer Patients

Maxygen, Inc. today announced that it has initiated a phase IIa trial to evaluate the efficacy, safety and tolerability of MAXY-G34 in the treatment of chemotherapy-induced neutropenia . MAXY-G34 is a novel pegylated granulocyte colony stimulating factor (PEG-GCSF) shown in preclinical and Phase I ...

Mount Sinai researchers find new Alzheimer's disease treatment promising

...nts with mild to moderate Alzheimer's disease. The two investigators, Giulio Maria Pasinetti, M.D., Ph.D. , and Hillel Grossman, M.D., presented Phase iia preliminary clinical findings at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD) in Vienna on Sunday, July 12....

New Report Just Published: World Hepatitis C Virus And Therapeutics Market Report

...ial of Telaprevir II-54 Amarillo and CytoPharm to Initiate Phase II Study of Novel Oral Interferon II-54 Biolex Releases Locteron(R) Phase iia Trial Results II-54 Schering-Plough Releases Details of Boceprevir Phase II Study II-54 Progenics Releases Pre-Clinical Results of PRO 206 II-...

Arete Therapeutics Presents Positive Clinical and Preclinical Data for AR9281

...f Executive Officer. "We anticipate that the results from our ongoing phase iia clinical program in pre-diabetic patients will establish proof of concept t... AR9281 Phase II Program Underway Arete is conducting a Phase iia multicenter, double-blind, placebo-controlled study of AR9281 in pre-diabet...

Migraine prevention by targeting glutamate receptors?

...tle (April 25 May 2), Addex Pharmaceuticals (SIX: ADXN) will present Phase iia data on ADX10059, a negative mGluR5 allosteric modulator, which shows effic...of of concept study in acute treatment of migraine attacks. In the Phase iia clinical trial of 129 migraine patients, significantly more patients taking...

PRA SPEAKING EVENT: Phase I Studies with Hepatitis C Compounds in Healthy Volunteers and Patients: Views from Inside

... on hepatitis C. Since 1995, he has supervised all aspects of Phase I and iia drug research for PRA's EDS group. With 228 beds in Europe and the U...rope, PRA's EDS group provides comprehensive services for Phase I and Phase iia studies. In the Netherlands, PRA EDS initiated the "Dutch Hepatitis Resear...

Novavax Reports Fourth Quarter and 2008 Year-End Financial Results

...favorable results from the second stage of a Phase iia clinical trial of its pandemic flu VLP vaccine can...nogenicity results in December 2008 from its Phase iia seasonal flu VLP vaccine dose-ranging study that started in September 2008. The Phase iia randomized, placebo controlled clinical trial eval...

IIa in Medical Technology

BioCis Pharma Reports Positive Phase IIa Clinical Results in Atopic Dermatitis

TURKU, Finland, July 3 /PRNewswire/ -- BioCis Pharma Ltd., a privately held drug development company with its headquarters in Turku, Finland, announced positive results from its Phase IIa clinical trial of ProtoCure(TM) emulsion cream, the company's novel topical drug for dermatology. This dou...

Vantia Therapeutics' Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia

SOUTHAMPTON, England, June 29 /PRNewswire/ -- Vantia Therapeutics, an emerging pharmaceutical company developing novel, small molecule drugs targeting large, underserved medical markets, announces positive results from a Phase IIa clinical trial of its lead development compound VA106483 for no...

Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial

Results show improved insulin sensitivity and lower glucose levels without the side effects of current therapies KALAMAZOO, Mich., May 14 /PRNewswire/ -- Metabolic Solutions Development Company (MSDC) announced today that its lead compound, MSDC-0160, can improve insulin sensitivity and lo...

TissueGene Announces Regulatory Allowance to Initiate Phase IIa Study of TG-C in South Korea for Osteoarthritis of the Knee

ROCKVILLE, Md., March 2 /PRNewswire/ -- TissueGene, Inc. announced today that its South Korean licensing partner Kolon Life Science, Inc. (KLS) has received regulatory allowance from the Korea Food and Drug Administration (KFDA) to initiate a Phase IIa clinical trial of TissueGene-C (TG-C) in pati...

Solace Pharmaceuticals Initiates Phase IIa Trial of Glial Cell Modulator SLC022 in Post-Herpetic Neuralgia

CAMBRIDGE, Mass., Jan. 12 /PRNewswire/ -- Solace Pharmaceuticals, a private biotechnology company discovering and developing innovative treatments for pain, announced the initiation of a proof-of-concept clinical trial of SLC022 in patients with post-herpetic neuralgia (PHN). PHN, a painful co...

Novavax Announces Top Line Results of Phase IIa Clinical Trial for Its Seasonal Influenza VLP (Trivalent) Vaccine Candidate

Favorable immunogenicity results for seasonal vaccine program follows positive results from its pandemic influenza vaccine Phase IIa trial in July 2008; plans to initiate a study of the seasonal vaccine in the elderly in 2009 ROCKVILLE, Md., Dec. 11 /PRNewswire-FirstCall/ -- Novavax, Inc...

Raptor Pharmaceuticals Corp. Announces Positive Phase IIa Clinical Study Results for Convivia(TM) Program

Reduction in Tachycardia and Blood Acetaldehyde Levels in Subset of Subjects with Inborn Error of Alcohol Metabolism NOVATO, Calif., Nov. 11 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced positive results in its ...

Regado Biosciences Completes Patient Enrollment for Phase IIa Study of REG1 Anticoagulation System

DURHAM, N.C., Oct. 10 /PRNewswire/ -- Regado Biosciences, Inc., announced today the Company has completed enrollment in the Phase IIa clinical study of its REG1 Anticoagulation System in patients undergoing elective percutaneous coronary intervention (PCI). REG1 is a two-component system compo...

Nile Therapeutics Announces Dosing in Phase IIa Study of CD-NP in Heart Failure Patients

SAN FRANCISCO, July 11 /PRNewswire-FirstCall/ -- Nile Therapeutics, Inc. (Nasdaq: NLTX ), today announced that it has dosed the first acute setting heart failure patient in its Phase IIa, multi-center, open-label, ascending dose clinical study of the company's lead product candidate, CD-NP, a...

Alba Therapeutics Announces the Presentation of Results of a Phase IIa Clinical Trial for Larazotide Acetate for the Treatment of Celiac Disease at the Digestive Disease Week Conference

BALTIMORE, May 21 /PRNewswire/ -- Alba Therapeutics Corporation announced today that data from its Phase IIa clinical trial were presented in the Clinical Advances in Celiac Disease session at the Digestive Disease Week (DDW) meeting in San Diego, California. Results of the randomized, double-...

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IIa in Biological News

UC Davis bench-to-bedside research: Promising treatment in clinical trials

...lood pressure, inflammation and diabetes is very attractive." The Phase iia clinical trial is a double-blind, placebo-controlled study. Officials will ...gimens." Said Arte's chief medical officer Randall Whitcomb: "The Phase iia trial will further validate the role of s-EH in the pathophysiology of dise...

Anabolic steroids provide a competitive edge in power lifting years after doping has ended

... relies heavily on muscle. The body's main muscle fiber types: type I, type iia and type IIB. Type I is the weakest and slowest, but has the most endurance. Type iia is the strongest and fastest, but has the least endurance. Human muscles oc...

Active ingredient in common Chinese herb shown to reduce hypertension

...nd treats cardiovascular disease. Tanshinone iia is an active ingredient of danshen. Since tanshinone iia is widely available, a team of researchers has use...l model, the scientists have found that tanshinone iia does reduce blood pressure. Summary of Me...

IIa in Biological Technology

BioCis Pharma Starts Phase IIa Trial in Psoriasis

TURKU, Finland, March 12 /PRNewswire/ -- BioCis Pharma Ltd., a privately-held drug development company with its headquarters in Turku, Finland, announced that it has begun a new Phase IIa clinical testing of ProtoCure(TM) emulsion cream, the company's novel topical drug for dermatology. The do...

Novavax Completes Enrollment of Its Seasonal Influenza VLP Vaccine Phase IIa Clinical Trial

Rapid Seasonal influenza VLP vaccine trial enrollment positions Company to report top line data in fourth quarter of this year ROCKVILLE, Md., Sept. 19 /PRNewswire-FirstCall/ -- Novavax, Inc. (Nasdaq: NVAX ) announced today it has completed enrollment of healthy volunteers in a Phase ...

Presentation of Phase IIa Results for Cytos Biotechnology's Hypertension Vaccine at the American Heart Association Scientific Sessions 2007

Oral Presentation by Prof. Juerg Nussberger, MD, Today at 9.45am (EST): "CYT006-AngQb, a Vaccine Against Hypertension Targeting Angiotensin II, Reduces Early-Morning and Day-Time Blood Pressure." The American Heart Association Publishes Today an Independent News Release ...

Revotar Reports First Positive Clinical Results From Phase IIa Study in COPD

HENNIGSDORF and BERLIN, Germany, October 31 /PRNewswire/ -- Revotar Biopharmaceuticals AG., today announced first positive results from an investigator driven open labelled Phase IIa pilot study in 14 patients with stable COPD stage 0 to II (GOLD criteria) inhaling 70 mg of Bimosiamose twice a...

EnVivo Pharmaceuticals Announces Results and Successful Completion of EVP-6124 Phase Ib/IIa Trial at the International Conference on Alzheimer's Disease

...Cognitive Disorders and Schizophrenia. The company's lead product is an alpha-7 nicotinic acetylcholine receptor agonist and has been tested in Phase iia clinical trials for cognition disorders in Alzheimer's disease and Schizophrenia. The company's other programs include an epigenetics program based o...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

...t of viral diseases, Santaris Pharma is responsible for the discovery and development of RNA inhibiting drug candidates through to completion of Phase iia ("Clinical Proof of Concept") for four viral targets, at which point GlaxoSmithKline will have an exclusive option to license each compound for furthe...

Palkion Selects Novel Oral Development Candidate for the Treatment of Anemia

...lammation and novel antibiotics. The lead candidate, CG100649 is a next generation NSAID with high safety and efficacy, which recently completed phase iia of 248 patients for osteoarthritis in Europe. CG200745 is an oral/IV HDAC inhibitor for cancer and CG400549 is a novel antibiotic against MRSA and VRS...

Vantia Therapeutics Appoints Rachel Morten as Head of Regulatory Affairs

...ontinues to mature." Rachel Morten, Head of Regulatory Affairs, said: "Vantia has already made great progress with its pipeline, with the Phase iia trial of VA106483 for nocturia recently completed and dosing complete in the Phase I trial of VA111913 for dysmenorrhoea. These products target condit...

Aerovance Secures $38 Million in Equity Financing

...of uncontrolled asthma. AeroTrial is a late-stage clinical study using a dry powder formulation and follows positive clinical data from two Phase iia studies in which Aerovant demonstrated significant benefit in asthmatics who were experimentally challenged with inhaled allergen ( The Lancet 2007, ...

Orcrist Bio Inc. Receives Approval from European Competent Authority to Initiate its Planned Phase I, Open-label, Single-ascending-dose, Safety Study of HYC750

...is financed by its founders and by private investors. About InPEC BV InPEC BV is a clinical CRO that focuses on the execution of Phase I and iia clinical trials. Its professional and experienced team, and state of the art facilities, embedded within the care of a private hospital with an ICU un...

IIa in Biological Definition

Muscle

...use when a person excercises regularly, type IIx fibers tend to become type iia fibers (at least a fraction of them does). Thus, sedentary people have a higher proportion of type IIx fibers. type iia fibers : are also used for strength-and-power activities, but can sustain a...

IIa in Biological Dictionary

Gyrase

...e . Along with gyrase , most prokaryotes also contain a second type iia topoisomerase, ... Type I topoisomerase - Type II topoisomerase ( gyr...in the ... In addition to gyrase , many bacteria contain another Topo iia named Topo IV. ... The CTD of gyrase is indeed responsible for the positi...