IDO

Researchers work to boost effectiveness of the flu vaccine

...or and David Munn, showed in 1998 that fetuses use ido to avoid rejection by the mother's immune system. ...ne Development. "I think if we can understand how ido regulates the response to viral infections, we can...e. They also are using different methods to block ido in the mouse model then see what happens to the in...

Blue Cross and Blue Shield of Minnesota and American Well(TM) Join to Bring Online Care to Minnesota

...am for the state of Minnesota. "We are excited to partner with Blue Cross to bring on-demand health care access to the people of Minnesota," said ido Schoenberg, M.D., CEO of American Well Corporation. "The introduction of virtual clinics creates a model for new care options across the nation, while...

First in the Nation, HMSA's Online Care Goes Live

... use the new health care service to maintain their health. "We're proud to partner with HMSA to improve access to physician care in Hawaii," said ido Schoenberg, M.D., chairman and chief executive officer of American Well Corporation. "The results from early participants are encouraging and demonst...

American Well Selects First DataBank's Drug Data for Use in Online Physician-Patient Care Consultations

...y of patient care. "This integrated offering will put drug information at the fingertips of physicians during the actual care encounter," said ido Schoenberg, MD, Chief Executive Officer of American Well, Inc. "This information, together with other tools and the power of live interaction will pro...

New approaches to protecting transplanted organs make first steps toward patients

...exploring the most effective method for increasing ido levels to improve transplant survival. The grant a...transplant biologist in Dr. Mellor's lab, will use ido stimulators before, during and after a transplant. They'll also use ido inhibitors to further define IDO's role in graft s...

IDO2 an active enzyme to target in pancreatic cancer

...volved with the study. According to Dr. Brody, ido is an enzyme that represses the immune system, thu...R) in Wynnewood, Pa., previously reported that the ido inhibitor D-1-methyl-tryptophan (1-MT), preferenti...may respond to a therapeutic strategy including an ido inhibitor, a potential novel drug for pancreatic c...

Researchers aim to over-stress already taxed mantle cell lymphoma cells

... David Munn is exploring IDO's therapeutic potential in cancer. Fetuses use ido to avoid rejection by the mother's immune system and tumors appear to use it as well. Dr. Bhalla suspects an ido inhibitor, already under study for lung cancer and other tumors, likely wil...

Blue Cross Blue Shield of Hawaii and American Well Bring Online Care to the State of Hawaii

...vide the people of Hawaii access to Online Care. In realizing our collaborative vision, HMSA is leading major transformation in U.S. healthcare," said ido Schoenberg, M.D., CEO of American Well Corporation. "Together, we are bringing affordable and convenient quality healthcare to people's homes." In a...

American Well and Microsoft Enter Into a Strategic Collaboration to Bring Healthcare to People's Homes

...hael Gold, chief operating officer of HMSA. "Convenient, immediate and affordable online care in people's homes is becoming a reality in 2008," said ido Schoenberg, M.D., chief executive officer of American Well. "With HealthVault, we can offer better data-enriched communication, device connectivity, a...

Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread

...ntists looking at other cancers has indicated that ido (indolamine 23 dioxygenase) is critical to regulat...cancer cells residing in the lymph nodes expressed ido to avoid being found, and if so, could they target...rson Medical College and their co-workers analyzed ido expression in 14 lymph nodes to which pancreatic c...

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IDO in Biological News

Team identifies a molecular switch linking infectious disease and depression

... Journal of Immunology , is the first to identify ido (indoleamine 2,3 dioxygenase) as a molecular switc...body fight infection. These proteins also activate ido in the body and brain. ido degrades the amino acid tryptophan, producing meta...

Potential new HIV drug may help patients not responding to treatment

...to hold the immune system back. In healthy people, ido prevents the immune system from attacking the body. HIV and SIV hijack the machinery that makes ido and use it to stop the immune system from attackin... works," said Dr Boasso. In healthy people, the ido enzyme controls allergic reactions and autoimmune ...

Molecule that suppresses immune response under study in type 1 diabetes

...ansient defect in their dendritic cells that hurts ido expression. Dendritic cells, which can express IDO...r last year reported that when dendritic cells and ido are depleted in the mouse, the disease gets worse.... was formal evidence that the dendritic cells with ido were putting the brakes on the disease," said Dr. ...

DNA component can stimulate and suppress the immune response

...n MCG's Immunotherapy Center, they've also learned ido inhibits inflammation by blocking production of in...r that causes inflammation. "This suggests that ido is a counter-regulatory mechanism that serves as a...m occurring." The researchers already knew that ido protects tumors from the immune system. While work...

NSF funds new 'Center for the Physics of Living Cells' at Illinois

...al fellows to join the effort. The recruits will work with 12 center members, including physics professors Paul Selvin, Nigel Goldenfeld, Yann Chemla, ido Golding, Aleksei Aksimentiev and Karin Dahmen along with chemistry professors Zaida Luthey-Schulten and Martin Gruebele, biochemistry professor Stephe...

JCI table of contents: Aug. 16, 2007

...ting mice with both a chemotherapeutic drug and a chemical inhibitor of IDO, but not either agent alone, leading the authors to suggest that combining ido inhibitors with chemotherapeutic agents might improve the efficacy of chemotherapeutics in individuals with cancer. TITLE: Plasmacytoid dendritic c...