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Hypotension in Medical News

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...s including, but not limited to, flushing, shortness of breath, facial swelling, headache, chills, back pain, tightness in the chest or throat, and/or hypotension have occurred in up to 10 percent of patients treated with DOXIL. In most patients, these reactions have resolved within several hours to a day once t...

Favorable Vote From FDA Advisory Committee on SEROQUEL Pediatric Supplemental New Drug Applications

...4% vs. 3%-13%), dizziness (9%-18% vs. 5%-7%), constipation (8%-10% vs. 3%-5%), asthenia (5%-10% vs. 3%-4%), abdominal pain (4%-7% vs. 1%-3%), postural hypotension (4%-7% vs. 1%-2%), pharyngitis (4%-6% vs. 3%), weight gain (5%-6% vs. 1%-3%), lethargy (5% vs. 2%), nasal congestion (5% vs. 3%), SGPT increased (5% v...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

... higher levels of prolactin elevation than other antipsychotic agents. Orthostatic Hypotension: RISPERDAL(R) CONSTA(R) may induce orthostatic hypotension associated with dizziness, tachycardia, and in some patients, syncope, especially during the initial dose-titration period. Monitoring should be consi...

Olanzapine Long-Acting Injection (LAI) Efficacy and Safety Data Presented at American Psychiatric Association Annual Meeting

... antipsychotic increase. The syndrome may remit, partially or completely, if antipsychotic treatment is withdrawn. Zyprexa may induce orthostatic hypotension associated with dizziness, tachycardia, bradycardia, and in some patients, syncope, especially during the initial dose-titration period. Particular ca...

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

... higher levels of prolactin elevation than other antipsychotic agents. Orthostatic Hypotension: RISPERDAL(R) CONSTA(R) may induce orthostatic hypotension associated with dizziness, tachycardia, and in some patients, syncope, especially during the initial dose-titration period. Monitoring should be consi...

AZOR(R) Receives FDA Approval as First-Line Treatment for High Blood Pressure

...NS, Fetal/Neonatal Morbidity and Mortality . hypotension in Volume- or Salt-Depleted Patients In patient...volume- and/or salt-depleted patients, symptomatic hypotension due particularly to the olmesartan component may o...e to amlodipine in AZOR is gradual in onset, acute hypotension has rarely been reported after oral administration...

Video: FDA approves Exforge HCT(R) - the Only High Blood Pressure Treatment to Combine Three Medications in a Single Pill

...ia or hypersensitivity to other sulfonamide-derived drugs. Excessive hypotension was seen in 0.4% of patients treated with EXFORGE and in 1.7% of patients t...r salt-depletion before administering EXFORGE or EXFORGE HCT or symptomatic hypotension may occur. Caution should be observed when initiating therapy with EXFORGE...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

...), dyspepsia (5%-7% vs. 1%-4%), dizziness (10%-13% vs. 4%-11%), orthostatic hypotension (7% vs. 5%), weight gain (7% vs. 1%), increased appetite (12% vs. 6%), fati...%), asthenia (5%-10% vs. 3%-4%), abdominal pain (4%-7% vs. 1%-3%), postural hypotension (4%-7% vs. 1%-2%), pharyngitis (4%-6% vs. 3%), weight gain (5%-6% vs. 1%-3%...

What do neurologists do for entertainment?

... of his feet. What is the diagnosis? (Answer: arsenic neuropathy.) A 17-year-old girl falls from a horse and develops a headache. (Cerebrospinal fluid hypotension syndrome.) A lung cancer patient suffers progressive weakness and numbness in the legs. (Leptomeningeal carcinomatosis.) And there's the occasional...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

...), dyspepsia (5%-7% vs. 1%-4%), dizziness (10%-13% vs. 4%-11%), orthostatic hypotension (7% vs. 5%), weight gain (7% vs. 1%), increased appetite (12% vs. 6%), fati...%), asthenia (5%-10% vs. 3%-4%), abdominal pain (4%-7% vs. 1%-3%), postural hypotension (4%-7% vs. 1%-2%), pharyngitis (4%-6% vs. 3%), weight gain (5%-6% vs. 1%-3%...
Hypotension in Medical Technology

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... antipsychotic increase. The syndrome may remit, partially or completely, if antipsychotic treatment is withdrawn. Zyprexa may induce orthostatic hypotension associated with dizziness, tachycardia, bradycardia, and in some patients, syncope, especially during the initial dose-titration period. Particular ca...

Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables

...tandard of care includes diuretics and vasodilators. Available agents from both of these classes of agents have been associated with renal impairment, hypotension and adverse outcomes. About Relaxin Relaxin is a naturally occurring peptide hormone that acts as a systemic and renal vasodilator. Elevated...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... higher levels of prolactin elevation than other antipsychotic agents. Orthostatic Hypotension: RISPERDAL(R) CONSTA(R) may induce orthostatic hypotension associated with dizziness, tachycardia, and in some patients, syncope, especially during the initial dose-titration period. Monitoring should be consi...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

...Mortality in the prescribing information . hypotension in Volume- or Salt-Depleted Patients In patient...treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with BENIC...t should start under close medical supervision. If hypotension does occur, the patient should be placed in the su...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

...rug-related AEs included: dizziness (3.4 percent), hypotension (2.2 percent), and/or headache (1.1 percent). ... patients, 2.2%), headache (4 patients, 2.2%), and hypotension (4 patients, 2.2%). Among individual treatment reg...nd Mortality in the prescribing information. hypotension in Volume- or Salt-Depleted Patients In patient...

New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure

...NS, Fetal/Neonatal Morbidity and Mortality. hypotension in Volume- or Salt-Depleted Patients In patient...volume- and/or salt-depleted patients, symptomatic hypotension due particularly to the olmesartan component may o...e to amlodipine in AZOR is gradual in onset, acute hypotension has rarely been reported after oral administration...

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

...ble treatment effect, led to treatment discontinuation in only 2.8 percent of patients, and does not pose a safety concern. Incidences of orthostatic hypotension among RAPAFLO(TM)- and placebo-treated patients were similar and low (2.6% and 1.5%, respectively). In addition, the incidence of treatment-related d...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

...sometimes resulted in accidents. Hallucinations and postural (orthostatic) hypotension may occur. In clinical trials for early PD using immediate release tablets,...fects of pramipexole that were more frequent than with placebo are postural hypotension (53% vs. 48%), dyskinesia (47% vs. 31%), extrapyramidal syndrome (28% vs. 2...

Watson Announces United States Availability of RAPAFLO(TM) (silodosin), a Novel New Treatment in Benign Prostatic Hyperplasia (BPH)

...east a three-point improvement in IPSS score, regardless of age or severity of symptoms. RAPAFLO(TM) is associated with a low incidence of orthostatic hypotension and the associated symptoms of syncope, fainting and dizziness. "The launch of RAPAFLO(TM) is an important milestone and, coupled with the forthc...

Results From Study Show Promising Efficacy and Safety Results for Corthera's Relaxin in Acute Heart Failure

...andard of care includes diuretics and vasodilators. Available agents from both of these classes of agents have been associated with renal impairment, hypotension and adverse outcomes. About Relaxin Relaxin is a naturally occurring peptide hormone that acts as a systemic and renal vasodilator through...
Hypotension in Medical Definition

Space medicine

...ial edema and other unwelcome side effects. Upon return to earth, the blood begins to pool in the lower extremities again, resulting in orthostatic hypotension . External links Description of space medicine References http://science.nasa.gov/headlines/y2002/25mar_dizzy.htm ...
Hypotension in Medical Dictionary

Hypotension

In physiology and medicine, hypotension refers to an abnormally low blood pressure. This is best understood as a physiologic state, rather than a disease. It is often associated with shock, though not necessarily indicative of it. Hypotension is the opposite of... In physiology and me...

Syncope

...ated from other conditions that may cause a ... Pain and emotional stress can trigger vasovagal syncope in susceptible people. ... Orthostatic hypotension — Another cause of syncope is orthostatic hypotension. ... Syncope - Cleveland Clinic Heart and Vascular Institute, leader in heart care and...

Low blood pressure

...er and to weight ... Overview of the condition featuring common causes, care options, and more. Information about low blood pressure or hypotension which occurs when the blood pressure during and after each heartbeat is much lower than usual. There are many potential causes of low bloo...

CSF leak

... CSF leaks can also occur in the nose after trauma or surgery, and following ... considering the diagnosis of CSF leak are orthostatic hypotension (which can ... ... used in the past was that a definitive CSF leak exists when the glucose content ... of CSF rhinorrhea is the identif...

Acute tubular necrosis

...) ... ... most common causes of acute tubular necrosis (ATN) are hypotension and nephrotoxins. ... Acute Tubular Necrosis . Prerenal Azotemia. Rat...Nephritis ... most common causes of acute tubular necrosis (ATN) are hypotension and nephrotoxins. ... ACUTE TUBULAR NECROSIS . by Geoffrey K. Dub...
Hypotension in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...s including, but not limited to, flushing, shortness of breath, facial swelling, headache, chills, back pain, tightness in the chest or throat, and/or hypotension have occurred in up to 10% of patients treated with DOXIL. In most patients, these reactions have resolved within several hours to a day once the infu...

Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting

...sychosis; QT prolongation; neuroleptic malignant syndrome; tardive dyskinesia; hyperglycemia and diabetes mellitus; weight gain; seizures; orthostatic hypotension and syncope; leukopenia, neutropenia and agranulocytosis; hyperprolactinemia; body temperature regulation; dysphagia; suicide; priapism; potential for...

Nile Therapeutics Announces Focus on CD-NP for Acute Heart Failure and Termination of 2NTX-99 Program

...ute heart failure, including B-type natriuretic peptide, have been associated with favorable pharmacologic effects, but have also been associated with hypotension and decreased renal function which limit their utility in clinical practice. CD-NP was designed to preserve the favorable effects of current therapie...

Sangart, Inc. Announces Key Executive Appointments and Company Restructuring

...art. "Our recent successful Phase III clinical studies of Hemospan demonstrated very encouraging efficacy results for the prevention and treatment of hypotension in hip replacement procedures. These trials provide a platform from which to conduct the pivotal clinical studies that will be necessary to establish...

Nile Therapeutics Announces Positive Results from Phase 1b Safety and Pharmacodynamics Study of CD-NP in Patients with Heart Failure

...es up to an MTD of 20 ng/kg/min. Dose escalation was limited by symptoms of hypotension observed at 30 ng/kg/min, which represents a dose of approximately 3- to 6-...ed with favorable pharmacologic effects, but have also been associated with hypotension and decreased renal function which limit their utility in clinical practice...

Interim Analysis of Top-Line Data From Phase II/III Study Shows Favorable Efficacy & Safety for Corthera's Relaxin in Acute Heart Failure

...atients, the current standard of care includes diuretics and vasodilators. Both of these classes of agents have been associated with renal impairment, hypotension and adverse outcomes. About Relaxin Relaxin is a naturally occurring peptide hormone that acts as a systemic and renal vasodilator. Elevated level...

Top-Line Preliminary Data From Phase II/III Study of Corthera's Relaxin in Acute Heart Failure to be Presented in Satellite Symposium at AHA Scientific Sessions 2008

...atients, the current standard of care includes diuretics and vasodilators. Both of these classes of agents have been associated with renal impairment, hypotension and adverse outcomes. About Relaxin Relaxin is a naturally occurring peptide hormone that acts as a systemic and renal vasodilator. Elevated level...

FDA Approves Astellas' Vaprisol(R) (Conivaptan Hydrochloride Injection) Premixed in 5% Dextrose for the Treatment of Hyponatremia

...d patients (3%) than among placebo-treated patients (0%). Other common adverse reactions were headaches (8%, 10%), hypokalemia (22%, 10%), orthostatic hypotension (14%, 6%), and pyrexia (11%, 5%) for Vaprisol 20mg/day and 40mg/day, respectively. For full prescribing information, please visit http://www.Vaprisol...

Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure

... right atrial pressure -- Trend toward increase in cardiac output -- No hypotension -- No change in serum creatinine About the Study The objective of the ...ed with favorable pharmacologic effects, but have also been associated with hypotension and decreased renal function which limit their utility in clinical practice...

FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania

... (25-52% vs. 10-13%), dry mouth (12-37% vs. 1-7%), constipation (6-10% vs. 3-6%), dyspepsia (5-7% vs. 1-4%), dizziness (10-13% vs. 4-11%), orthostatic hypotension (7% vs. 5%), weight gain (7% vs. 1%), increased appetite (12% vs. 6%), fatigue (6-7% vs. 2-4%), dysarthria (5% vs. 0%), and nasal congestion (5% vs. 1...
Hypotension in Biological Definition

Yellow fever

... proteinuria. If the disease progresses, delirium, seizures and coma ensue. hypotension and dehydration are also common. Mortality is around 5%. Patients who die u... Treatment is symptomatic and supportive only. Fluid replacement, fighting hypotension and transfusion of blood derivates is mostly needed in severe cases. In ren...
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