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Hyponatremia in Medical News

FDA Approves SAMSCA(TM) (tolvaptan), the First and Only Oral Vasopressin Antagonist to Treat Patients With Clinically Significant Hypervolemic and Euvolemic Hyponatremia

Once-Daily SAMSCA Increases Serum Sodium Levels Through Increase in Free Water Clearance TOKYO and PRINCETON, N.J., May 21 /PRNewswire/ -- Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development and Commercialization, Inc. (OPDC) announced today that the U.S. Food and Drug...

Astellas Launches Vaprisol(R) (Conivaptan Hydrochloride Injection) Premixed in 5% Dextrose for the Treatment of Hyponatremia

Arginine vasopressin (AVP) receptor antagonist now available in new premixed formulation DEERFIELD, Ill., April 1 /PRNewswire/ -- Astellas Pharma US, Inc. today announced the commercial availability of Vaprisol (R) (conivaptan hydrochloride injection) Premixed in 5% Dextrose, a new premi...

ReachMD XM 157 Announces Medical Information Feature on Treatment Options for Management of Hyponatremia

CHICAGO, Oct. 27 /PRNewswire/ -- ReachMD XM 157 announces a new "Medical Industry Feature of the Week" highlighting a vasopressin receptor antagonist and its effects on management of euvolemic and hypervolemic hyponatremia in the hospital setting. ReachMD XM 157, the first and only network f...

Data Show Vaprisol(R) Is Effective & Safe in Promptly Increasing Serum Sodium Levels in Patients With Euvolemic or Hypervolemic Hyponatremia

DEERFIELD, Ill., Oct. 10 /PRNewswire/ -- Astellas Pharma US, Inc. today announced results of an analysis showing that Vaprisol (conivaptan hydrochloride injection) produced a prompt and sustained (over the 4-day treatment period) increase in serum sodium concentration [Na+] among hospitalized ...

Athletes Warned Of Exercise-Associated Hyponatremia

Novice athletes who are training for marathon running events may be a danger from exercise-associated //hyponatremia (EAH) that can develop from low levels of sodium in the body. The risk to the condition is heightened when the athletes drink excess amounts of fluids during exercises. Awarenes...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Commercial Availability of Savella(TM)

... other SNRIs and SSRIs withdrawal symptoms have been observed following discontinuation of milnacipran. A gradual dose reduction is recommended. hyponatremia may occur as a result of treatment with SSRIs and SNRIs, including Savella. Discontinuation should be considered for patients with symptomatic hypona...

FDA Approves Symbyax(R) as First Medication for Treatment-Resistant Depression

... warfarin or other drugs that affect coagulation. As with other antidepressants, Symbyax has been associated with cases of clinically significant hyponatremia that appeared to be reversible when Symbyax was discontinued. As with any CNS-active drug, Symbyax has the potential to impair judgment, thinkin...

Forest Laboratories, Inc. Announces FDA Approval of Lexapro(R) for the Treatment of Major Depressive Disorder in Adolescents

...tics or who are otherwise volume-depleted appear to be at a greater risk. Discontinuation of Lexapro should be considered in patients with symptomatic hyponatremia and appropriate medical intervention should be instituted. The concomitant use of Lexapro with other SSRIs, SNRIs, triptans, tryptophan, antipsy...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Revised Timing for Commercial Availability of Savella(TM)

... other SNRIs and SSRIs withdrawal symptoms have been observed following discontinuation of milnacipran. A gradual dose reduction is recommended. hyponatremia may occur as a result of treatment with SSRIs and SNRIs, including Savella. Discontinuation should be considered for patients with symptomatic hypona...

Prescription Copay Assistance for Patients taking Gleevec or Tasigna for Philadelphia chromosome-positive Chronic Myelogenous Leukemia (Ph+ CML)

...hosphatase. Check hepatic function tests periodically. Electrolyte abnormalities Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hyponatremia and hypocalcemia. Correct electrolyte abnormalities prior to initiating Tasigna and monitor periodically during therapy. Hepatic impairment Met...
Hyponatremia in Medical Technology

Study Shows VAPRISOL(R) is Effective in Increasing Serum Sodium Levels and Well-Tolerated in Patients With Euvolemic or Hypervolemic Hyponatremia

DEERFIELD, Ill., Oct. 25 /PRNewswire/ -- Astellas Pharma US, Inc. today announced data demonstrating that VAPRISOL(R) (conivaptan hydrochloride injection) effectively raises serum sodium concentration ([Na+]) and is well-tolerated among hospitalized patients with euvolemic or hypervolemic hypo...

Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia

- Phase III data published in the American Journal of Nephrology - DEERFIELD, Ill., Sept. 20 /PRNewswire-FirstCall/ -- Astellas Pharma US, Inc. today announced that its Phase III data on VAPRISOL was published in the September issue of the American Journal of Nephrology. In this study, VAPR...

Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)

...hopenia, ALT elevation, AST elevation and cholesterol elevation). Of these laboratory abnormalities in pirfenidone patients, all but one case each of hyponatremia and lymphopenia were Grade 3. In four of the laboratory tests, Grade 3/4 abnormalities were noted slightly more frequently in patients treated with p...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

...heck hepatic function tests periodically. Electrolyte abnormalities Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hyponatremia and hypocalcemia. Correct electrolyte abnormalities prior to initiating Tasigna and monitor periodically during therapy. Hepatic impairment ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...se. Check hepatic function tests periodically. Electrolyte abnormalities Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hyponatremia and hypocalcemia. Correct electrolyte abnormalities prior to initiating Tasigna and monitor periodically during therapy. Hepatic impairment ...

Study Demonstrates Lexapro(R) Significantly Improves Depression Symptoms in Adolescents

...tics or who are otherwise volume-depleted appear to be at a greater risk. Discontinuation of Lexapro should be considered in patients with symptomatic hyponatremia and appropriate medical intervention should be instituted. The most common adverse events with Lexapro versus placebo (approximately 5 percent or grea...

Everest Data on Short- and Long-Term Use of Otsuka's Investigational Novel Treatment, Tolvaptan, Published in Journal of the American Medical Association and Featured in ACC's Late Breaking Clinical Trials

...difference in body weight numerically favored tolvaptan through week 56. The long-term trial also documented that tolvaptan patients who enrolled with hyponatremia (serum sodium less than 134 mEq/L) exhibited significantly greater corrections in serum sodium at day seven or discharge, if earlier, (p less than 0.0...
Hyponatremia in Medical Products

PK Plasma-CISE/Plasma-CUT

Features:... Saline Safety- Increases safety and precision and eliminates dilutional hyponatremia Improved Visualization Limited thermal risk outside the target tissue Reduced Bleeding ...
Company:GYRUS ACMI
Hyponatremia in Medical Definition

Gastric lavage

...children, normal saline is used as children are more at risk of developing hyponatremia if lavaged with water. Because of the possibility of vomiting, a suction d...mplications include laryngospasm , hypoxia , bradycardia , epistaxis , hyponatremia , hypochloremia , water intoxication , or mechanical injury to the stomac...

Pathology

...calcaemia / Disorders of calcium metabolism Fluid, electrolyte and acid-base balance Electrolyte disturbance - Na + Hypernatremia / hyponatremia - Acidosis ( Metabolic , Respiratory , Lactic ) - Alkalosis ( Metabolic , Respiratory ) - Mixed disorder of acid-base balance - H 2 O Deh...
Hyponatremia in Medical Dictionary

Hemolytic anemia

.... The Merck Veterinary Manual (MVM) has served veterinarians and other animal health professionals as a concise and ... with hemolytic anemia , hyponatremia ... Hemolytic anemia - Washington Hospital Center is located in Washington DC ... Idiopathic autoimmune hemolytic anemia . Non-immune hemo...
Hyponatremia in Biological News

Runners -- Let thirst be your guide

... long distance cycling. This serious condition, known as exercise-induced hyponatremia (EAH), could be prevented if only people would respect their personal thirs...Verbalis, “and if they do, it can only be due to fluid retention.” The hyponatremia consensus panel has recommended that everyone, including endurance exercise...
Hyponatremia in Biological Technology

FDA Approves Astellas' Vaprisol(R) (Conivaptan Hydrochloride Injection) Premixed in 5% Dextrose for the Treatment of Hyponatremia

Arginine vasopressin (AVP) receptor antagonist now approved in single-use premixed formulation DEERFIELD, Ill., Oct. 22 /PRNewswire/ -- Astellas Pharma US, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new premixed formulation of V...

U.S. Food and Drug Administration Advisory Committee Recommends Approval of Tolvaptan, an Investigational Treatment for Hyponatremia

PRINCETON, N.J., Jun. 25 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) Advisory Committee on Cardiovascular and Renal Drugs voted to recommend the approval of tolvaptan, Otsuka Pharmaceutical Development & Commercialization, Inc.'s (OPDC) investigational treatment for patients wi...

New Drug Application for Tolvaptan, Otsuka's Investigational Novel Oral Treatment for Worsening Heart Failure and Hyponatremia, Accepted by the U.S. Food and Drug Administration

... known predictor of death in patients with serious underlying illnesses.(6) hyponatremia has long been associated with neurological symptoms including in its worst ...l serum sodium is between 135 to 145 mEq/L, whereas patients diagnosed with hyponatremia have sodium levels of less than 135 mEq/L.(8) About Otsuka Pharmaceutical...
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