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Hypoglycemia in Medical News

Use of Mealtime Pramlintide Added to Basal Insulin Showed Similar Improvements in Glycemic Control Compared to Rapid-Acting Insulin, With Lower Risk of Hypoglycemia and Without Weight Gain: Data Presented at ADA 2009

Additional Analyses Showed Pramlintide Improved Treatment Satisfaction and Quality of Life NEW ORLEANS, June 6 /PRNewswire-FirstCall/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN ) today announced data showing that the use of mealtime SYMLIN(R) (pramlintide acetate) injection improved gluc...

Comprehensive Review on Sulfonylureas in the Latest Issue of Diabetic Hypoglycemia (05 June 2009)

LONDON, June 4 /PRNewswire/ -- The latest issue of the online journal Diabetic Hypoglycemia ( http://www.hypodiab.com ) features an authoritative review on sulfonylureas by Professor Ian Campbell, a leading expert in oral hypoglycemia therapy. Professor Campbell's review focuses on sulf...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

New data presented at the 61st Annual Scientific Meeting of the Gerontological Society of America showed JANUVIA™ (sitagliptin), a diabetes medicine from Merck & Co., Inc., significantly reduced blood sugar levels in elderly patients with type 2 diabetes and was not associated with hypo...

A rare association: Non-islet cell tumor hypoglycemia

Non-islet cell tumor hypoglycemia (NICTH) is a rare association between spontaneous hypoglycemia and tumors derived from tissues other than the pancreatic islets. It was initially associated with abdominal soft tissue sarcomas, although other tumor types have been described. The pathogenesis o...

Severe Hypoglycemia And Spatial Memory In Children With Type 1 Diabetes

A new study, which appears in the October issue of the journal Diabetes Care, demonstrates that high frequency of and early exposure to severe hypoglycemia during development negatively affects spatial long-term memory performance//. Severe hypoglycemia is a significant and relatively common com...

New Book Helps Those with Bipolar Disorder Manage Diets - and Lives

...h from diabetes, heart disease and stroke. "I read a medical textbook that explained how many people with bipolar disorder also have reactive hypoglycemia -- that is low blood sugar that occurs one to three hours after a meal," she said. "The symptoms include fatigue, depression, irritability, ...

Determining Insulin Pump Need for Diabetics

...on't achieve tight glycemic control and the hemoglobin A1c rises above the recommended seven percent set by the American Diabetes Association, or when hypoglycemia continues despite adjusting insulin doses. "Programming the pump to adjust basal insulin delivery rates and boluses throughout the day allows for more...

Tight Management of Type 1 Diabetes Worth the Effort

...lication -- low blood sugar (hypoglycemia). Severe hypoglycemia that resulted in either a coma or seizure occurred...ber of severe episodes, but a lack of awareness of hypoglycemia and hypoglycemia remain big problems. The bottom line, she said,...

Amylin Pharmaceuticals Reports Second Quarter Financial Results

...injection. Treatment with exenatide once weekly also led to statistically significant improvements in body weight, with reduced incidence of confirmed hypoglycemia Signed joint supply agreement with Lilly to develop a pen device for exenatide once weekly that will enable patients to mix and administer the m...

Patients Suffering from Diabetes Now Have the Option to Suffer No More with Diabetic Free All Natural Medical Herbal Extracts Capsules

...process which enhances the efficacy of blood-sugar utilization, thus stabilizing and balancing both blood sugar levels and blood pressure Treats hypoglycemia and hyperglycemia   The capsules treat conditions in which a drastic drop of blood sugar level occurs (hypoglycemia), as well as cond...
Hypoglycemia in Medical Technology

Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients

Latest data on ultra rapid acting insulin presented at the American Diabetes Association's 69th Scientific Sessions NEW ORLEANS, June 6 /PRNewswire-FirstCall/ -- The findings of two 52-week studies show that the investigational ultra rapid acting insulin AFRESA(R) (insulin human [rDNA or...

DiObex, Inc. Awarded Patent for the Prevention of Insulin-Induced Hypoglycemia

Patent Protects Very Low Dose Glucagon ahead of Phase 2 Clinical Trials in 2008 SAN FRANCISCO, Jan. 8 /PRNewswire/ -- DiObex, Inc., a privately held biotechnology company developing treatments for metabolic diseases, announced today that it has secured a critica...

Exenatide Once Weekly Provided Superior Glucose Control Compared to Lantus(R) in Head-to-Head DURATION-3 Study

...atide once weekly experienced less confirmed hypoglycemia: the incidence of hypoglycemia was 4 percent with exenatide once weekly versus 19 percent with Lantus for ...ight along with other parameters of glucose control, cardiovascular health, hypoglycemia and patient-reported outcomes. Subjects in both treatment groups are contin...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

...d with a significantly greater incidence of severe hypoglycemia than was insulin glargine (11.1% vs 7.6% respectiv...ly, p=0.0439) and mean yearly rates of symptomatic hypoglycemia (7.08+/-16.49 vs 5.13+/-12.79, p=0.0017). The...d with a significantly greater incidence of severe hypoglycemia than was insulin glargine (11.1% vs 7.6% respectiv...

Spherix Announces Positive Phase 2 Study Results

...cluded from the study, as well as any having one or more episodes of severe hypoglycemia within six months prior to entry into the study, or currently diagnosed as having hypoglycemia unawareness. In this trial, Naturlose was safe and well tolerated. Lo...

Meta-Analysis of Clinical Data Showed No Increased Risk of Cardiovascular Events Associated With Exenatide Use: Data Presented at ADA 2009

...iazolidinedione. BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight loss...ey. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, th...

Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009

...ts were receiving exenatide once weekly. No severe hypoglycemia was observed. The safety profile of patients treat...rovides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, w...used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To re...

Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride: Oral 162

...increase in the glimepiride group (+1.1 kg). hypoglycemia is a condition where blood sugar levels become too low. Minor hypoglycemia was more than six times less frequent in the lirag... tolerability of liraglutide The rate of minor hypoglycemia was statistically significantly lower with both li...

New Study Showed Lantus(R) Plus One, Two or Three Shots of Apidra(R) Lowered Patients' Blood Sugar

...er but nonsignificant proportion of patients experienced serious and severe hypoglycemia with Apidra(R) 3 times daily compared with those receiving Apidra(R) once or twice daily. The rates of symptomatic or severe hypoglycemia were not statistically significant between groups. "By combining basal...

Boehringer Ingelheim Unveils Diabetes Pipeline

...agliptin compared to placebo were nasopharyngitis, (7.1 vs. 9.9 percent) diarrhea (2.5 vs. 4.2 percent) and nausea (3.5 vs. 4.2 percent). No cases of hypoglycemia were reported in patients receiving linagliptin.(1) "Many patients don't achieve adequate blood sugar control with commonly used diabetes medica...
Hypoglycemia in Medical Products

ACS:180 C-Peptide Assay

Description:... For The Detection Of Serum C-Peptide Levels. Clinical Uses Of C-Peptide Measurement: Evaluating patients with fasting hypoglycemia Assisting in the classification of diabetes mellitus Differentiating insulin dependent patients from noninsulin - dependent patients ...
Company:Siemens Medical Solutions Diagnostics

ADVIA Centaur C-Peptide Assay

Description:... For The Detection Of Serum C-Peptide Levels. Clinical Uses Of C-Peptide Measurement: Evaluating patients with fasting hypoglycemia Assisting in the classification of diabetes mellitus Differentiating insulin dependent patients from noninsulin - dependent patients ...
Company:Siemens Medical Solutions Diagnostics

AutoDELFIA® Insulin Kit

Description:... and heparin plasma using the AutoDELFIA Automatic Immunoassay System. The assay is used in the investigation, diagnosis and treatment of diabetes and hypoglycemia (low blood glucose level). The analytical sensitivity is typically better than 0.5 U/mL (3 pmol/L)....
Company:PerkinElmer Life And Analytical Sciences, Inc.
Hypoglycemia in Medical Definition

Pathology

...tis ) Pancreas Diabetes mellitus ( type 1 , type 2 , coma , angiopathy , ketoacidosis , nephropathy , neuropathy , retinopathy ) - hypoglycemia - Hyperinsulinism - Zollinger-Ellison syndrome Parathyroid Hypoparathyroidism ( Pseudohypoparathyroidism ) - Hyperparathyroidism ( ...
Hypoglycemia in Medical Dictionary

Hypoglycemia

Hypoglycemia or hypoglycaemia is the medical term for a state produced by a lower than normal level of blood glucose. The term literally means "under-sweet blood" . Support network for those who are troubled with blood-sugar disorders. Find out more about Hypoglycemia . What ...

Low blood sugar

...a reference range between about 3.6 and 5.8... hypoglycemia — Comprehensive overview covers symptoms, causes, ...akes your blood sugar level rise and fall. ... hypoglycemia and diabetes: How to treat low blood sugar ....sugar . Emergency treatment guide printouts. hypoglycemia is a condition that occurs when your blood suga...

Insulin Shock

... Insulin shock is a term that refers to severe hypoglycemia (low blood glucose) ... Insulin reactions...s and symptoms Diagnosis Treatment Alternative ... hypoglycemia (also known as a hypo, insulin shock , and a lo... ... Home " Health " Conditions & Treatments " hypoglycemia " How to Treat Insulin Shock ... What Is ...

Insulinoma

...or Insulinoma signs or Insulinoma symptoms. ... Books for Insulinoma . hypoglycemia (Algorithmic Diagnosis ... Insulinoma is a pancreatic tumor commonl...al of patients: ... Overview: Insulinomas are the most common cause of hypoglycemia resulting from endogenous hyperinsulinism.In a large single-center series ...

Hyperinsulinism

...g to a variety of congenital disorders in which hypoglycemia is caused by excessive insulin secretion. Congenital forms of hyperinsulinemic hypoglycemia can be transient or persistent, mild or severe. T...bout 60% of babies with hyperinsulinism develop hypoglycemia during the first ... Title: Practical manag...

Hyperinsulinemia

...ession, dyslipidemia, diabetes, hyperinsulinemia , asthma, sleep apnea, ... Overview: Primary hyperinsulinism is a rare but important cause of hypoglycemia ... Hyperinsulinemia ... Ketonuria does not rule out hyperinsulinemia . ... Hyperinsulinemia High blood insulin levels. ... the differen...

Glucagonoma

...nd prognosis. ... diagnoses, misdiagnosis, and correct diagnosis for Glucagonoma signs or Glucagonoma symptoms. ... Books for Glucagonoma . hypoglycemia (Algorithmic ... Glucagonoma - Overview, Glucagonoma is a very rare tumor of the islet cells of the pancreas, which release the hormones in...

Epinephrine

... More about Hypoglycemia: Causes and symptoms Diagnosis Treatment Alternative treatment Prevention ... Epinephrine : should be elevated during hypoglycemia ... Learn about the prescription medication Marcaine (Bupivacaine Hydrochloride and Epinephrine Injection), drug uses, dosage, side effects...

Acanthosis nigricans

... ... Acanthosis Nigricans may lighten up and possibly go away by treating the root ... Acanthosis Nigricans . Growth in Children. Diabetes. hypoglycemia (Low Blood Sugar) ... Acanthosis nigricans can affect otherwise healthy people, or it can be ... Obesity can lead to acanthosis nigricans...
Hypoglycemia in Biological News

Fear of hypoglycemia a barrier to exercise for type 1 diabetics

This press release is available in French . Montreal, November 26, 2008 According to a new study, published in the November issue of Diabetes Care , a majority of diabetics avoid physical activity because they worry about exercise-induced hypoglycemia (low blood sugar) and severe conseque...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

...and; How Do Beta Cells Respond to Increased Demand in People? Lessons from Pregnancy, Gestational Diabetes, and the Evolution of Type 2 Diabetes). hypoglycemia Casey Donovan, Ph.D., professor of kinesiology and biology, will discuss his research on the role of the brain and the portal vein in sensing and ...

Study shows CGM devices also benefit people with type 1 diabetes

.... Today, the JDRF study has shown that, with CGM, hypoglycemia can be reduced while maintaining excellent blood s...y with glucose values in the potentially dangerous hypoglycemia range. The authors demonstrated a number of other...d sugar levels without increasing the frequency of hypoglycemia in adults over 25 years of age in a randomized tri...

Master gene plays key role in blood sugar levels

...ne called a coactivator fast for a day, their blood sugar levels plummet. If they go another day without food, they will die. The severity of the hypoglycemia (low blood sugar) was unexpected, said Dr. Bert W. O'Malley, chair of molecular and cellular biology at Baylor College of Medicine and senior author o...

JDRF to provide $1M in funding to SmartCells, Inc.

...unlike currently available insulins, SmartInsulin is designed to maintain continuous, tight control of blood glucose levels while reducing the risk of hypoglycemia like the pancreas does automatically in the absence of diabetes. As part of the agreement, JDRF will provide $1 million in first-year funding to supp...

New once-a-week treatment for type 2 diabetes developed by Mount Sinai researcher

...s defined by reaching target glucose levels. Patients treated with Exenatide once weekly also experienced fewer side effects, had no increased risk of hypoglycemia (decrease in blood sugars) and saw reductions in body weight. Dr. Drucker has studied the gut hormone GLP-1 for over 20 years. Multiple drugs base...

Treatment corrects severe insulin imbalance in animal studies

...eting beta cells in the pancreas. Insulin levels rage out of control and severely reduce blood glucose, a condition called hypoglycemia. If untreated, hypoglycemia may cause irreversible brain damage or death in children. Congenital HI occurs in an estimated one in 50,000 U.S. children, with a somewhat higher inc...

Blood sugar's manufacture limited by building blocks' supply

...esearchers found that mice with a targeted deletion of KLF15 display severe hypoglycemia after an overnight fast. They further found evidence that defective amino acid breakdown promotes the development of fasting hypoglycemia in the mutant animals by limiting the availability of a glucose substrate c...

Glucose triggers brain cell death in rats after hypoglycemic coma

...ood to extremely low levels –?a condition known as hypoglycemia –?and cause hypoglycemic coma, resulting in destru... was only when we gave them glucose to reverse the hypoglycemia that the oxidative stress occurred. This was a re... bad for rat brains. The way we treat patients for hypoglycemia may have to be reevaluated." Swanson adds two...

Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

...s. Both adult patients suffered skin irritation, while both adolescents had potentially life-threatening reactions, including liver toxicity and hypoglycemia (low blood sugar), as well as nausea, vomiting and dizziness. One of the teens also had disrupted heart rhythms. All four patients recovered afte...
Hypoglycemia in Biological Technology

New Drug Application for Exenatide Once Weekly Accepted for Review by FDA

...iazolidinedione. BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight loss...ey. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, th...

Glenmark's Novel Molecule for Diabetes, Melogliptin to Enter Phase III Trials

... best-in-class in achieving glycemic control with low incidence of hypoglycemia and neutral effect on body weight - Global Phase III trials likely to ...file. In addition, patients taking Melogliptin experienced low incidence of hypoglycemia and neutral effect on body weight. In this 12-week, randomized, doub...

Hospira Announces Plans to Integrate Symbiq(R) and EndoTool(R) Technologies

...the appropriate precision to manage blood glucose levels in a variety of hospital settings. Overly aggressive insulin therapy can increase the risk of hypoglycemia (low blood glucose), an independent risk factor for mortality (2)(3). EndoTool software can operate on a hospital's existing computer system, and is c...

Exenatide Once Weekly New Drug Application Submitted to FDA for Type 2 Diabetes

...iazolidinedione. BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight loss...ey. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, th...

Exenatide Clinical Data Analysis Shows No Increased Risk of Cardiovascular Events

...iazolidinedione. BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight loss...ey. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, th...

New Data From Head-to-Head Phase 3 Trial Demonstrate That Liraglutide is More Effective Than Exenatide in Treatment of Type 2 Diabetes

...tter blood glucose control and also had less minor hypoglycemia than those treated with exenatide." Fasting plas...rmin and/or a sulphonylurea. The overall rate of hypoglycemia in the study was low. Liraglutide patients experienced significantly less minor hypoglycemia compared to those on exenatide. Nausea was the m...

Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA

...n add-on therapy for people currently using metformin, a sulfonylurea, or a thiazolidinedione. BYETTA provides sustained A1C control, low incidence of hypoglycemia when used with metformin or a thiazolidinedione, and progressive weight loss. BYETTA was approved in April 2005 and has been used by approximately one...

ReceptorBio Announces Diabetes License Agreement With Telik

...single agents, lower glucose levels in models of diabetes. The compounds are active in the presence of sub-maximal levels of insulin, and do not cause hypoglycemia at the dose levels examined. This synergy with insulin suggests the compounds could potentially be co-administered with other anti-diabetic agents inc...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

...re hypoglycemia, particularly in patients with type 1 diabetes. When severe hypoglycemia associated with SYMLIN use occurs, it is seen within three hours following ... thiazolidinedione. BYETTA provides sustained A1C control, low incidence of hypoglycemia when used with metformin or a thiazolidinedione, and progressive weight los...

DiObex and Camurus Sign License Agreement for the Development of DIO-901 in FluidCrystal(R) Extended Release Technology

... Development program for prevention of insulin-induced hypoglycemia in diabetes SAN FRANCISCO and LUND, Sweden...ease formulation of low dose glucagon for the prevention of insulin-induced hypoglycemia in patients with diabetes. "Intensive glycemic control is beneficial for ...
Hypoglycemia in Biological Definition

Diabetes mellitus

...nd coma 3.5 Hyperosmotic diabetic coma 3.6 hypoglycemia 4 Long-term complications 5 Manag...ections , or delivering a baby with macrosomia or hypoglycemia . Criteria for diagnosis Diabetes melli...one; it is less common in type 1 diabetics. hypoglycemia ...

Insulin

...se 5 Signal transduction 6 The brain and hypoglycemia 7 Diseases and syndromes caused by an insulin...h restore satisfactory blood glucose levels after hypoglycemia must be quick and effective because of the immedi...ms are indeed generally efficient, and symptomatic hypoglycemia is found almost entirely in diabetics using insuli...
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