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Hypersensitivity in Medical News

Is somatic hypersensitivity a predictor of irritable bowel syndrome?

Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported si...

Settlers Suffered from Nightmares, Hypersensitivity in Eve of Disengagement

Harsh figures regarding the mental state of the evacuated settlers from Gaza Strip, eve of the disengagement plan led by the Israeli government, were exposed// in a new study conducted by the National Security Center in the University of Haifa. 54% of the respondents reported difficulty in concentr...

FDA Approves New 3000 IU Vial Size for Kogenate(R) FS, antihemophilic factor (recombinant)

... The most serious adverse reactions are systemic hypersensitivity reactions and the development of high titer inhibi...ted or minimally treated patients, skin-associated hypersensitivity reactions, infusion site reactions, and central ve...nts who have manifested life-threatening immediate hypersensitivity reactions, including anaphylaxis, to the product o...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

...) injection site reactions occurred in two percent or less of patients receiving FIRMAGON. FIRMAGON is contraindicated in patients with known hypersensitivity to degarelix or to any of the product components. FIRMAGON is not indicated in women or pediatric patients. Long-term androgen deprivation therapy p...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

...ings & Precautions Severe Skin Reactions : Severe and potentially life-threatening skin reactions, including Stevens-Johnson Syndrome, hypersensitivity reaction, and erythema multiforme, have occurred (<0.1%) in patients taking INTELENCE. Treatment with INTELENCE should be discontinued and appropri...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...evere side effects. Do not substitute for doxorubicin HCl on a mg per mg basis Contraindications Patients with a history of hypersensitivity reactions to a conventional doxorubicin formulation or the components of DOXIL Nursing mothers Additional Safety Information ...

Wyeth's Prevenar 13* Receives First Approval

...sed sleep. Risks are associated with all vaccines, including Prevenar 13. hypersensitivity to any vaccine component, including diphtheria toxoid, is a contraindicatio...sh. Risks are associated with all vaccines, including Prevenar. hypersensitivity to any vaccine component, including diphtheria toxoid, is a contraindicatio...

Watson Pharmaceuticals Resumes Shipment of INFeD(R) (Iron Dextran Injection, USP)

... INFeD should be used with caution in individuals with histories of significant allergies and/or asthma, and is contraindicated in patients with hypersensitivity to the product and patients with all anemias not associated with iron deficiency. Allergic reactions may potentially still occur in patients who have...

Bayer HealthCare Launches Hemophilia Self-Infusion Training Program

... The most serious adverse reactions are systemic hypersensitivity reactions and the development of high titer inhibi...ted or minimally treated patients, skin-associated hypersensitivity reactions, infusion site reactions, and central ve...nts who have manifested life-threatening immediate hypersensitivity reactions, including anaphylaxis, to the product o...

Dry mouth linked to prescription and over the counter drugs

...g, swallowing, or speaking. Foamy or stringy saliva, irritation of the tongue, burning of the tissues inside the mouth, painful ulcerations and dentin hypersensitivity (extreme sensitivity in one or more teeth) are also dry mouth symptoms. Over time, xerostomia sufferers may experience extensive tooth decay, tooth l...
Hypersensitivity in Medical Technology

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

... used to treat acute asthma episodes (including status asthmaticus) where extra measures are required. ASMANEX is not for patients who have a hypersensitivity (including allergic reactions) to mometasone or any of the ingredients in ASMANEX. There have been cases of hypersensitivity, allergic reactions, faci...

ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients

...t be used to treat acute asthma episodes (including status asthmaticus) where extra measures are required. ASMANEX is not for patients who have a hypersensitivity (including allergic reactions) to mometasone or any of the ingredients in ASMANEX. There have been cases of hypersensitivity, allergic reactions, faci...

Dry Mouth Linked to Prescription and Over the Counter Drugs

...g, swallowing, or speaking. Foamy or stringy saliva, irritation of the tongue, burning of the tissues inside the mouth, painful ulcerations and dentin hypersensitivity (extreme sensitivity in one or more teeth) are also dry mouth symptoms. Over time, xerostomia sufferers may experience extensive tooth decay, tooth l...

Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets

...tation, flatulence, exacerbation of UC, headache, rhinitis, nasopharyngitis and pain. Asacol and Asacol HD are contraindicated in patients with hypersensitivity to salicylates. Caution should be exercised when using these products in patients with known renal dysfunction or history of renal disease. It is rec...

Data Demonstrated ACTEMRA(R) (tocilizumab) Significantly Inhibited Progression of Structural Joint Damage in Rheumatoid Arthritis Patients

...zerland and India. The serious adverse events reported in ACTEMRA clinical studies include serious infections, gastrointestinal perforations and hypersensitivity reactions including anaphylaxis. The most common adverse events reported in clinical studies were upper respiratory tract infection, nasopharyngitis, ...

Study Results Present Efficacy and Safety Findings from the PHIRST-1 Study of Patients with Pulmonary Arterial Hypertension Taking Tadalafil Tablets Once Daily

...pressure. If a patient experiences anginal chest pain after taking ADCIRCA they should seek immediate medical attention. Patients with a known serious hypersensitivity to tadalafil (ADCIRCA or CIALIS) should not take ADCIRCA. PDE5 inhibitors, including tadalafil, have mild systemic vasodilatory properties that m...

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

...in 2003. Certican is not approved for use in the US. Afinitor important safety information Afinitor is contraindicated in patients with hypersensitivity to everolimus, to other rapamycin derivatives or to any of the excipients. Potentially serious adverse reactions include non-infectious pneumonitis an...

Shire Presented Results of a New Database Analysis on Lialda(R) (Mesalamine) and Other 5-ASAs for Ulcerative Colitis at Digestive Disease Week

... have not been established. Lialda is contraindicated in patients with hypersensitivity to salicylates (including mesalamine) or to any of the components of Lialda...ome is suspected, prompt withdrawal is required. Mesalamine-induced cardiac hypersensitivity reactions (myocarditis and pericarditis) have been reported. Reports of ren...

Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting

...tions Leukine is contraindicated in patients with excessive leukemic blasts in bone marrow or peripheral blood (10 percent), in patients with known hypersensitivity to GM-CSF, yeast derived products or any component of Leukine, and for concomitant use with chemotherapy and radiotherapy. Serious allergic or anaphy...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...treat patients with advanced renal cell carcinoma after failure of treatment with sunitinib or sorafenib. Afinitor is contraindicated in patients with hypersensitivity to everolimus, to other rapamycin derivatives or to any of the excipients. Potentially serious adverse reactions include non-infectious pneumonitis an...
Hypersensitivity in Medical Products

SAFESKIN* PURPLE NITRILE* Exam Gloves

Description:...oduct family offers a comprehensive line of non-sterile and sterile gloves. The gloves were designed as an alternative for those who may have a Type 1 hypersensitivity to natural rubber latex proteins. The unique COLOR PURPLE* provides quick, visual differentiation from latex and other synthetic gloves. Custom de...
Company:Kimberly-Clark/Ballard Medical Products

SAFESKIN* PURPLE NITRILE* Sterile Single

Description:...inical procedures when an exceptionally resistant non-latex glove is required. Theyre designed as an alternative for individuals who may have a Type 1 hypersensitivity to natural rubber latex proteins. Reaching for a single glove enhances convenience and prevents waste. And textured fingertips enhance grip in wet and...
Company:Kimberly-Clark/Ballard Medical Products
Hypersensitivity in Medical Definition

Pathology

... external agents Coalworker's pneumoconiosis - Pneumoconiosis - Silicosis - Bauxite fibrosis - Berylliosis - Siderosis - Byssinosis - hypersensitivity pneumonitis ( Farmer's lung , Bird fancier's lung ) Other, principally affecting the interstitium Acute respiratory distress syndrome - ...
Hypersensitivity in Medical Dictionary

Vasculitis

...oms, causes, treatment of this inflammation of the blood vessels. ... hypersensitivity vasculitis . ... This section of the Lupus Foundation of America's web...iety. ... can target the blood vessels resulting in vasculitis . ... hypersensitivity Vasculitis . Kawasaki Disease. Microscopic Polyangiitis. Polyarteritis Nod...

Serum sickness

...of hypersensitivity, specifically immune complex hypersensitivity (type III). The term serum sickness–like reactio...... Overview: Serum sickness is a type III hypersensitivity reaction that results ... The incidence of seru.... Background: Serum sickness is a type III hypersensitivity reaction that results ... The incidence of seru...

Radiculopathy

...tions which have caused damage to ... Doctors use the term radiculopathy to specifically describe pain, and other ... Radiculopathy can create hypersensitivity to touch as well as numbness in the ... A cervical radiculopathy is a problem that results when a nerve in the neck is ... Let's look at the...

Purpura

... Purpura may be secondary to thrombocytopenia, platelet dysfunction, coagulation ... Henoch-Schönlein purpura is an IgA-mediated, autoimmune, hypersensitivity ... Purpura may be defined as visible, unblanching hemorrhages in the skin or mucous ... Purpura - Overview, Purpura is purple-colored spo...

Peanut Allergy

... Peanut allergy is a type of food allergy distinct from nut allergies. It is a hypersensitivity to dietary substances from peanuts causing an overreaction of the immune system which in a small percentage of people may lead to... Informati...

Nephritis

... is Allergy information includes articles on allergies, symptoms, treatment, medications, food ... Acute nephritis is most commonly caused by hypersensitivity ... What is lupus nephritis ? Lupus nephritis is an inflammation of the kidney caused ... Lupus nephritis may cause weight gain, high ...

Latex Allergies

... ... Latex allergy can cause symptoms of stuffy nose, hives, wheezing and ... also can have food allergies . ... A latex allergy is a hypersensitivity to latex , which is used in the manufacture of a number of health-care and consumer products. NY Allergist for Allergy , Sinus & Asthma Cent...

Immunology

...y members ... The study of immunology has been both a source of important discoveries for many ... Immunology Animations IgE Mediated (Type I) hypersensitivity ... The IMMUNOLOGY ® 2006 Md. Abraham LICHTMAN. All the material in these site is protected by ... Immunology . Vols. 1 to 124; 1958 to 2008. V...

Hives

...s firmly stroked. ... Read an article explaining a common rash and its many causes. ... Hives are a sign that the whole body is experiencing a hypersensitivity reaction. ... Urticaria is another term for " hives . ... An episode of hives can start as itching, followed by swollen, red welts. ... Infectio...

Henoch

...0 criteria for the classification of Henoch -Schönlein purpura" ... hypersensitivity vasculitis and Henoch -Schönlein purpura: a comparison between the 2 d...rpura, Henoch -Schönlein purpura ... Henoch -Schonlein is a type of hypersensitivity vasculitis and inflammatory ... Symptoms of Henoch -Scholnlein purpura ...
Hypersensitivity in Biological News

Common chemotherapy drug triggers fatal allergic reactions

... School of Medicine identified 287 unique cases of hypersensitivity reactions submitted to the FDA's Adverse Event Rep...o 10 percent of actual incidence, so the number of hypersensitivity reactions and deaths is likely significantly highe...ions before the chemotherapy to reduce the risk of hypersensitivity reactions. The study was led by Charles Bennet...

American Chemical Society's Weekly PressPac -- May 20, 2009

...mmunogenum ) was first identified in 2000 as the potential cause of a mysterious disease that had been occurring among machinists. The illness, called hypersensitivity pneumonitis (HP), is an inflammation of the lung resulting from the body's immune reaction to bacteria, mold, and other airborne particles. At HP outb...

Even natural perfumes may cause allergies

... hypersensitivity to perfumes is the most common contact allergy in adults. Research at the University of Gothenburg has demonstrated that even natural aromatic oils, w...

12-month ATLANTA trial data show sustained benefit of Catania Stent

...the questions and issues surrounding drug-eluting stents and the increased risk of late and very late stent thrombosis, malapposition, inflammatory or hypersensitivity reactions, as well as the economic impact of maintaining long-term dual antiplatelet therapy," said Corrado Tamburino, MD, PhD, FESC, FSCAI, FSICI-GIS...

Alcohol is associated with risk of perennial allergic rhinitis

...been proposed that alcohol consumption may be one of the factors contributing to the rise in AR, especially because alcohol is a well-known trigger of hypersensitivity reactions and there is evidence that it influences the immune system. The 5,870 women studied were aged 20-29 years and free of seasonal and perenn...

Eribulin mesylate demonstrated anti-tumor activity in patients with advanced breast cancer

...infusion on Days 1 and 8 of a 21-day cycle. Patients received a median of four cycles of eribulin mesylate (range 1-27). No premedication to prevent hypersensitivity was required. Two-hundred sixty-nine patients met the key inclusion criteria. In patients who received a median of four cycles of eribulin mesylat...

Biomarkers allow doctors to match therapy to patient

...r-expressors had hormone receptornegative tumors (P = 0.02). Following vaccination, immunologic responses were similar as measured by delayed-type hypersensitivity reaction; however, patients in the vaccination arm who were low-expressors of HER2 demonstrated an increased number of E75-specific CD8+ T cells when ...

Researchers expand efforts to explore functional landscape of the human genome

...n of Active Functional Elements in Human Chromatin. These researchers will seek to identify and characterize regions of open chromatin through DNase I hypersensitivity assays, formaldehyde-assisted isolation of regulatory elements and chromatin immunoprecipitation for a few key DNA-binding factors. Chromatin is the c...

A new target for painkillers

... snail toxins named RgIA and Vc1.1 can treat nerve hypersensitivity and pain by blocking a molecule in cells known as ...as given. The highest dose completely reversed the hypersensitivity caused by sciatica, with no adverse effects. Daily...that "about 10 billionths of an ounce reversed the hypersensitivity to pain," McIntosh says. Vc1.1 had a similar ...

Langerhans cells regulate immune reactions in the skin

...l Chromosome transgenics to develop a mouse model that lacks Langerhans cells in the skin from birth. They stimulated the skin of these mice to create hypersensitivity similar to a poison ivy reaction. They expected that mice without Langerhans cells would have less immune response in the skin. "Unexpectedly, ins...
Hypersensitivity in Biological Technology

ANX-514 Reduces Hypersensitivity Reactions Without Impacting Pharmacokinetics or Antitumor Activity in Preclinical Tests

ADVENTRX Presents Results at 2007 AACR-NCI-EORTC International Conference SAN DIEGO, Oct. 25 /PRNewswire-FirstCall/ -- ADVENTRX Pharmaceuticals, Inc. (Amex: ANX ), a biopharmaceutical research and development company focused on commercializing proprietary product candidates for the treatment o...

FluMist(R) Begins Shipping for 2009-2010 Influenza Season

...istration only. Who may not be able to get FluMist? FluMist is not right for everyone. FluMist must not be given to: people with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine; people with life-threatening reactions to previous influenza vaccinations; and children and ad...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...r, fussiness, and crying. Other adverse reactions may occur. Known systemic hypersensitivity reaction to any component of Pentacel vaccine or a life-threatening reactio...eactions may occur. ActHIB vaccine is contraindicated in persons with known hypersensitivity to any component of the vaccine. The decision to give ActHIB vaccine shoul...

New Test from Quest Diagnostics Helps Physicians Choose HIV Antiretroviral Therapy in Patients with History of Drug Resistance

...diagnostic testing to monitoring HIV viral load, determining a viral genotype, and testing for the HLA-B*5701 genetic marker as an aid in predicting a hypersensitivity reaction to abacavir (Ziagen(R)), an antiretroviral therapy. About HIV and AIDS HIV, or the human immunodeficiency virus, is a retrovirus th...

Cumberland Pharmaceuticals Announces FDA Approval of Caldolor(TM)

...ll as the reduction of fever in adults. It is the first FDA approved intravenous therapy for fever. Caldolor is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, patients with asthma, urticaria, or allergic type reactions after taking aspirin or other NSAIDs. Caldolor is contraindi...

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

...ility, drowsiness, restless sleep, decreased appetite, vomiting, diarrhea, and rash. Risks are associated with all vaccines, including Prevenar. hypersensitivity to any vaccine component, including diphtheria toxoid, is a contraindication to its use. Prevenar does not provide 100% protection against vaccine se...

ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema

...upper respiratory infection, sinusitis, rash and headache. No drug-related serious adverse events (SAEs) have been observed in clinical trials. Severe hypersensitivity reactions may occur. Thrombotic events have occurred in patients receiving high dose off-label C1 inhibitor therapy well above the approved treatment ...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... in patients with CHF. Exercise caution when using CIMZIA in patients who have heart failure and monitor them carefully. Symptoms compatible with hypersensitivity reactions, including angioedema, dyspnea, hypotension, rash, serum sickness, and urticaria, have been reported rarely following CIMZIA administration....

HHS Awards MedImmune Contract to Manufacture Live Attenuated Nasal Spray Vaccine for Novel Influenza A (H1N1)

...uenza disease caused by influenza virus subtypes A and type B contained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life- threatening reactions to previous influenza vaccinations, and in children and ado...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... Contraindications Patients with a history of hypersensitivity reactions to a conventional doxorubicin formulation or the components of DO...is contraindicated in patients with uncontrolled hypertension or with known hypersensitivity to albumin (human) or mammalian cell-derived products. A...
Hypersensitivity in Biological Definition

Antibody

...s 190 kD. It can be found on the surface of the plasma membrane of basophils and mast cells of connective tissue . IgE plays a role in immediate hypersensitivity and the defense of parasites such as worms. The IgE antibodies are present also in outer excretions. They do not activate complement. Function...
Hypersensitivity in Biological Dictionary

Tetracycline

...infections, Rocky Mountain spotted fever, trachoma. Tetracycline may be confused with tetradecyl sulfate ... Tetracycline binds to calcium. ... hypersensitivity to tetracycline or any component of the ... Tetracycline (doxycycline, minocycline). Authoritative facts about the skin from the New Zealand .....

Norepinephrine

...e, norepinephrine also belongs to the family of compounds called ... hypersensitivity to norepinephrine , bisulfites (contains metabisulfite), or any ... Norep...agnostic group differences were seen for norepinephrine excretion. ... hypersensitivity to norepinephrine , bisulfites (contains metabisulfite), or any ... Norep...

Epinephrine

...inephrine also epinephrin n. A hormone secreted by the adrenal medulla that is released into the bloodstream in response to physical or mental hypersensitivity to epinephrine or any component of the ... Eligible patients were randomized to intravenous vasopressin (40 units) or epinephrine (1 mg) ... Al...

Colchicine

...ed colchicine patient information - includes colchicine description, dosage and directions. ... Because colchicine was developed prior to ... hypersensitivity to colchicine or any component of the formulation; severe renal, ... The amount of colchicine administered intravenously in an acute treatment per...

Cell-mediated immunity

...nvolves T lymphocytes) produced in the cells of ... cell - mediated immunity (CMI) ... Examples of Cell - Mediated Immunity . Delayed-Type hypersensitivity (DTH): the tuberculin test ... Cell Mediated and Humoral Immunity ... are produced primarily by B Cell lymphocytes. The body's cell medi...

Antigenic determinant

...e)) antibody, rabbit ... Immunochemistry: Uncertainty About the Antigenic Determinant : This article review of the role of cephalosporins in IgE hypersensitivity reactions in an attempt to ... Mouse protein-coding gene Kin. Represented by 87 ESTs from 57 cDNA libraries. ... Mus musculus antigenic determ...
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