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Hypercalcemia in Medical News

Product Shifts are Occurring in the Renal Anemia and Bone and Mineral Metabolism Markets According to the Most Recent TreatmentTrends(R): US Nephrology Report from BioTrends Research Group

...tion. Nephrologists report that barriers to increased use of both Zemplar and Genzyme's Hectorol in CKD center around reimbursement and incidences of hypercalcemia and hyperphosphatemia. Amgen's Sensipar continues to be used in less than one third of dialysis patients, although Nephrologists continue to project ...

Cytochroma Announces Positive Comparative Data on CTA018 in Chronic Kidney Disease Model

...that CTA018 has significantly reduced activity and half-life in human enterocytes (intestinal cells), making CTA018 Injection far less likely to cause hypercalcemia (excessive blood calcium) or hyperphosphatemia (excessive blood phosphorus). (3) CTA018 Preserves Vitamin D Status Currently available vitamin D h...

FDA Accepts Genta's NDA Amendment as Complete Response for Genasense(R) Treatment of Chronic Lymphocytic Leukemia

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Announces Licensing Agreement for Worldwide Development and Commercialization of a Leading Oral Taxane, Tesetaxel

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, which has recently entered cl...

Firefly genes allow testing of new therapy against lymphoma

...doing so, the researchers developed what they hope will be the first animal model for the disease that includes a severe bone depletion called humoral hypercalcemia of malignancy (HHM), a condition that can affect four out of every five ATLL patients and shorten their lives. The study is published in the onlin...

Bradley Pharmaceuticals to Feature Elestrin(TM) at North American Menopause Society Annual Meeting

...n increase in gallbladder disease requiring surgery in postmenopausal women receiving estrogens has been reported. Estrogen therapy may lead to severe hypercalcemia in patients with breast cancer and bone metastases. Retinal vascular thrombosis has been reported in patients receiving estrogens. Estrogen products ...

Novartis files application with FDA for Zometa

...pproved by the FDA just two weeks ago (20 August 2001) for the treatment of hypercalcemia of malignancy (HCM), the most common life-threatening metabolic complicatio..., Novartis has received marketing clearances for Zometa in the treatment of hypercalcemia of malignancy (HCM) in more than 30 countries. "Bone complications can...
Hypercalcemia in Medical Technology

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...o/Forteo(R) groups. In addition, the occurrence of hypercalcemia was half that of Forteo(R) in the highest dose of ...natomic sites with less resorptive effect and less hypercalcemia compared to PTH and its analogs," said Louis O'Dea...alogs do not stimulate adverse bone resorption and hypercalcemia to the same extent as PTH, highlighting differing ...

New Analyses Indicate that Divigel(R) (estradiol gel) 0.1% Is a Valuable Option for Certain Postmenopausal Women With Hot Flashes

...but serious risks reported with estrogen therapy include certain cardiovascular disorders, certain malignant neoplasms, dementia, gallbladder disease, hypercalcemia and visual abnormalities. The most frequently reported adverse events in Divigel(R) clinical trials were nasopharyngitis, upper respiratory tract infe...

Genta Updates Progress of its Phase 3 Trial of Genasense(R) in Patients with Advanced Melanoma

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

FDA Lifts Clinical Hold on Genta's Tesetaxel, a Leading Oral Taxane

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genasense(R) Chemotherapy Program Yields High Response Rate in Patients with Stage 4 Melanoma

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Long-Term Followup in Phase 3 CLL Trial Shows Genasense(R) is Associated with Significantly Increased Survival in All Responders

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Clinical Programs Featured in Multiple Abstracts at the Annual Meeting of the American Society of Clinical Oncology

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Receives Key Patent Related to Oral Gallium Compound G4544

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Specialized Genasense(R) Clinical Trials Featured at AACR Meeting

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Radius Completes Enrollment of Phase II Clinical Trial of BA058 for Osteoporosis

...: i.e., stimulating bone formation with a limited effect on bone resorption. In Phase I studies, BA058 generally was well tolerated and did not induce hypercalcemia in doses up to 80 mcg. About Osteoporosis Osteoporosis is a leading cause of morbidity and mortality in elderly people worldwide. In the U.S. alon...
Hypercalcemia in Medical Products

MM-PTH RIA Test

Description:...ntrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients. Endres DB, et ...
Company:Diagnostic Systems Laboratories, Inc.

C-PTH RIA Test

Description:...ntrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients. Endres DB, et ...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH IRMA Test

Description:...ntrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients. Endres DB, et ...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH ELISA Test

Description:...ntrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and nonparathyroid hypercalcemia [3,4]. Additionally, PTH is helpful for assessing parathyroid function in renal failure and is often used for dialysis patients. Endres DB, et ...
Company:Diagnostic Systems Laboratories, Inc.
Hypercalcemia in Medical Dictionary

Hypercalcemia

familial hypocalciuric hypercalcemia /familial benign hypercalcaemia (Online ' ... ATC code V03#V03AG Drugs for treatment of hypercalcemia . v • d • e ... Find the causes, risk factors, symptoms, complications, tests, and treatment for it. ... Hypercalcemia affects a very smal...

Serum calcium

... metabolism or calcium homeostasis is the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcemia or hypocalcemia, which both can have important consequences... Serum calcium . Table of contents. Definition. Alternative Names. How the ... ...

Parathyroid adenoma

...he parathyroid glands, which are located in the neck. Parathyroid Adenoma . Ariane Staub Neish, MD. J Stevan Nagel, MD. B ... presented with hypercalcemia and elevated parathyroid hormone. ... Parathyroid ... Home. What are parathyroids? What can go wrong with them? What are the symptoms? ... da...

Milk-alkali syndrome

...rome , also called Burnett's syndrome in honour of Charles Hoyt Burnett, the American physician who first described it, is characterized by hypercalcemia caused by repeated ingestion of calcium and absorbable alkali . If untreated,... Milk - alkali syndrome is an acquired condition in which...

Hypervitaminosis A

... ( hypervitaminosis -D) in inflammatory disease ... A mild degree of hypercalcemia may not be immediately dangerous ... Severe hypercalcemia that has developed rapidly ( hypervitaminosis D) can result in death. ......

Hyperparathyroidism

...n by the authors of ... Hyperparathyroidism is a common cause of hypercalcemia. ... Primary hyperparathyroidism is the most frequent cause of hypercalcemia in ... A patient information handout on hyperparathyroidism , written by the author of ... Hyperparathyroidism is excessive production of para...

Calcitonin

... calcitonin receptor controls bone formation in ... Online Medical Dictionary and glossary with medical definitions ... Calcitonin is given in hypercalcemia (high blood calcium) to lower the calcium ... Calcitonin information including symptoms, causes, diseases, symptoms, treatments, and other ...
Hypercalcemia in Biological News

Gallium: A new antibacterial agent?

...ermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lung infections. As Ga is already FDA approved for the treatment of hypercalcemia of malignancy, these data suggest that Ga might be a promising new therapeutic for the treatment of infection with P. aeruginonsa, a major cause of in...
Hypercalcemia in Biological Technology

Independent Monitoring Board Recommends Completion of Accrual to Genasense(R) Phase 3 AGENDA Trial in Advanced Melanoma

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Incorporated Announces Second Quarter 2008 Financial Results and Corporate Highlights

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Announces Second Quarter 2008 Financial Results and Conference Call

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Fontus Pharmaceuticals Acquires Nephrology and Endocrinology Drug from Roche Laboratories Inc.

...herapy should always be started at the lowest possible dose and should not be increased without careful monitoring of serum calcium. In order to avoid hypercalcemia and related conditions, the optimal daily dose of ROCALTROL must be carefully determined for each patient. The safety and effectiveness of ROCALTROL i...

Genta Receives Notice of Allowances for European Patents Related to Composition and Processes for Tesetaxel, a Leading Oral Taxane

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Submits NDA Amendment to FDA for Genasense as Treatment of Chronic Lymphocytic Leukemia

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer-related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Secures Up to $40 Million Convertible Financing Facility to Fund Key Programs

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Incorporated Announces First Quarter 2008 Financial Results and Corporate Highlights

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Announces Transfer of its Common Stock to the OTC Bulletin Board

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...

Genta Announces Pending Transfer of its Common Stock to the Over-the-Counter Bulletin Board

...anite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. The Company has developed G4544, an oral formulation of the active ingredient in Ganite, that has recently entered cli...
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