Hydroxyapatite

Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix

...with and its ability to provide a superior scaffold for growth and differentiation of cells. It has also been used in combination with nanocrystalline hydroxyapatite to provide an innovative osteopromotive bone graft and also with human demineralized bone matrix (DBM) to improve the healing response of DBM containi...

Smith & Nephew Endoscopy's OSTEORAPTOR(TM) Anchor Provides Bioabsorbable Solution for Labral Tears in the Hip and Shoulder

... First hip anchor made from bioabsorbable hydroxyapatite (HA) ANDOVER, Mass., Feb. 25 /PRNewswire-Firs...hor is the first hip anchor to use Polylactic Acid hydroxyapatite (PLLA-HA). The key ingredient, hydroxyapatite (HA), is a mineral found naturally in bone. Studie...

Growing Preference for Composite Materials in Shoulder Fixation and Knee Ligament Reconstruction Markets

...rs in shoulder fixation. Suture anchors composed of composite materials are often embedded with various biocompatible and bioactive materials, such as hydroxyapatite and tricalcium phosphate. In 2008, many companies, including market leader Arthrex, launched composite suture anchors to compete with DePuy Mitek -- t...

Enhanced Cosmetic Procedures Plus New At-Home Treatments Give Patients More Options

...e once natural collagen was the only filler available, now the advent of synthetic collagens, several hyaluronic acids, L-polylactic acid, and calcium hydroxyapatite allow dermatologists to correct signs of aging from sunken cheeks to fine lines around the eyes and lips. "Fillers represent the most visible area of ...

Toothpick: New molecular tag IDs bone and tooth minerals

...pecific, practical method to spot the formation of hydroxyapatite in living systems or tissue samples. Materials sci...s of amorphous calcium phosphatea precursorand the hydroxyapatite crystal. To find a more specific, less destruct... chemical composition and the crystal structure of hydroxyapatite to bind to the mineral's surface. The peptide's ab...

Pioneer(R) Surgical Technology Introduces the BacJac(TM) Interspinous Decompression System to the European Spine Market

...Matrix(TM) for tissue regeneration. Angstrom(TM) Medica, Inc. is the first company to obtain FDA approval for a nanotechnology device - NanOss(TM) - a hydroxyapatite bone void filler. Pioneer's three divisions ... Orthopedic, Spinal and Biologic ... produce innovative, cost-effective solutions for surgical proced...

Pioneer(R) Surgical Technology, Inc. Continues to Prove Science Behind PEEK-on-PEEK(TM) Technology for Motion Preservation Devices

...Matrix(TM) for tissue regeneration. Angstrom(TM) Medica, Inc. is the first company to obtain FDA approval for a nanotechnology device -- NanOss(TM) -- hydroxyapatite bone void filler. The company's three divisions ... Orthopedic, Spinal and Biologic ... all work to produce state of the art, cost-effective solutions...

Collagen Matrix, Inc. Receives FDA 510(k) Clearance for SynOss(TM) Synthetic Mineral Bone Graft Material

...ss Synthetic Mineral is an osteoconductive calcium phosphate based bone graft material with an apatite structure similar to that of human bone. Unlike hydroxyapatite materials, SynOss' has a carbonate apatite structure which is comparable to the mineralized matrix structure of human bone. The similarity in structur...

Detection of Malignant Breast Tumors Made Simpler and More Effective

...ocation of hydroxyapatite, and therefore the breast cancer cells themselves, Frangioni notes. His group began working to develop agents to target hydroxyapatite six years ago, but efforts were stalled by the inability to manufacture large quantities of the agent. “It was a chemical catch–22,” he says. “Bispho...

Link Between Nanoparticles and Kidney Stones

...ristics with calcified bacteria that exist in freshwater lakes. However, studies could not confirm whether the nanoparticles are calcified bacteria or hydroxyapatite crystals that precipitated upon proteins present in the culture medium used to replicate the nanoparticles. Researchers did, however, identify chemica...

Hydroxyapatite in Medical Technology

MIV Therapeutics Announces Pivotal Test Results Further Validating Company Stent Coatings Meet Critical FDA Fatigue Guidelines

...otentially harmful interactions with bare metallic stents. The Company's unique ultra-thin coating platform is derived from an organic material called hydroxyapatite (HAp) which has demonstrated excellent safety and biocompatibility in vivo animal studies. Hydroxyapatite is a porous material that makes up the bone ...

MIV Therapeutics Announces Renowned Researcher to Detail Milestone Pre-Clinical Results at Prominent International Conference EuroPCR 2007

...otentially harmful interactions with bare metallic stents. The Company's unique ultra-thin coating platform is derived from an organic material called hydroxyapatite (HAp) which has demonstrated excellent safety and biocompatibility in vivo animal studies. Hydroxyapatite is a porous material that makes up the bone ...

Hydroxyapatite in Medical Products

ApaPore Hydroxyapatite Bone Graft Substitute

Description: ApaPore is a synthetic and porous hydroxyapatite. ApaPore is disease free, readily available and manufactured to a highly controlled specification providing a cost-effective bone graft. Surgical applications include spinal fusions, fracture fixation, treating bone defects....
Company:Apatech

Bio-Eye Hydroxyapatite (HA) Orbital Implant

Description: The Bio-eye hydroxyapatite (HA) orbital implant was conceived by Arthur C. Perry, M.D., in the early 1980s, after a comprehensive review of the literature on orbital implants, which included the earliest manuscripts dating back to 1885 (Mules 1885). This review, along with an ongoing dissatisfactio...
Company:Bio-Eye Orbital Implants

Pro Osteon 200R Bone Graft Substitute

Description:... Pro Osteon 200R is a resorbable, osteoconductive matrix consisting of hydroxyapatite and calcium carbonate. Originally cleared for use in oral maxillofacial procedures as a very slow resorbing material, the faster-resorbing Pro Osteon ...
Company:Biomet, Inc.

Bi-Ostetic Slow Resorbtion Bone Filler

Description:... Bi-Ostetic is a cost-effective synthetic bone filler tailored for slow resorbtion. Based on Tricalcium Phosphate (TCP) and hydroxyapatite (HAP), its composition mimics that of human bone. BAB formulates the chemistry and microstructure of Bi-Ostetic to enhance bone regeneration. This for...
Company:Berkeley Advanced Biomaterials

Healos Bone Graft Replacement

Description:... Healos is an osteoconductive matrix constructed of cross-linked collagen fibers that are fully coated with hydroxyapatite through a proprietary 360 accretion process. When combined with autogenous bone marrow aspirate, Healos provides an excellent environment for osteopro...
Company:DePuy Orthopaedics, Inc.

Ti/HA Peg & Sleeve System

Description:... The titanium sleeve is coated with hydroxyapatite (HA) which allows vascular ingrowth, firmly secures the peg in the sphere, and enhances biocompatibility. To hold prosthetic eye. For improved occular...
Company:FCI Ophthalmics Inc.

Ocu-pore Porous Orbital Implants

Description:... Ocu-pore Porous Orbital Implants are comprised only of synthetic, medical grade, hydroxyapatite and have a controlled microstructure designed to support soft tissue ingrowth. Ocu-pore is available in a range of convenient sizes. The material is m...
Company:Ceramisys

BiHAPro Acetabular Cup

Features:... Available in diameters 46 mm to 70 mm to meet all patient needs. Closed pore porous coating with hydroxyapatite coating for minimal wear debris ingress and long term fixation. (1, 2, 3, 4). Incorporates 3 radial fins and a rim flare for primary fixation and rota...
Company:Biomet Orthopedics, Inc

The Natural-Hip Family - Specialty Porous collarless HA

Features:...mily offers a variety of stem options to address high, medium, and low demand patients, as well as revision and other special patient needs. The first hydroxyapatite (HA) coating over CSTi. HA porous surfaces encourage effective filling of the proximal femur, avoiding further degeneration....
Company:Zimmer, Inc.

The Natural-Hip Family - Specialty Porous Collared HA

Features:...mily offers a variety of stem options to address high, medium, and low demand patients, as well as revision and other special patient needs. The first hydroxyapatite (HA) coating over CSTi. HA porous surfaces encourage effective filling of the proximal femur, avoiding further degeneration....
Company:Zimmer, Inc.

Hydroxyapatite in Medical Definition

Nuclear medicine

...an be preferentially taken up by bone . By chemically attaching technetium-99m to MDP, radioactivity can be transported and attached to bone via the hydroxyapatite for imaging. Any increased physiological function, such as due to a fracture in the bone, will usually mean increased concentration of the tracer. Th...

Hydroxyapatite in Biological News

Can a new implant coating technique create a new six million dollar man?

... Prof. Eliaz has discovered that his method of coating circumvents the disadvantages of plasma- spraying. The electrochemical process allows synthetic hydroxyapatite to more closely mimic the real material. Examined under a microscope, it is virtually indistinguishable from the body's own material ― which hel...

Crowning glory

...te. An example of such a coating material is the commercially available composite materials, such as "Bonelike" which is a synthetic bone material, hydroxyapatite reinforced with tiny glass particles. This material can be used to provide a layer on the surface of pure titanium that its developers hoped will lead...

Human embryonic stem cell -- derived bone tissue closes massive skull injury

...dable scaffold followed the endochondral lineage. Those grown on a composite scaffold made of biodegradable polymers and a hard, gritty mineral called hydroxyapatite went to the intramembraneous side. Biomaterial scaffolds provide a three-dimensional framework on which cells can proliferate and differentiate, s...

Contrast agent trials in swine

...inistered Pam800 reveals the bones of pigs with very high sensitivity. When hydroxyapatite is injected into the soft tissues, the contrast agent marks only the tiny hydroxyapatite crystals with high selectivity and sensitivity. This could allow it to sele...

Nanotechnology being used to improve biocompatibility of human prosthetics and implants

...hosphate (CP) coatings on titanium alloy implants are proving their worth in orthopaedic and dental applications. The most promising form of CP are hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 , HA) coatings used to promote rapid bone remodelling on the titanium alloy implants. It is well known that the microstructure...

Protein-coated dental implants could improve bone regeneration

...ir effect on healing bone defects, they found some ?including some in use today ?that actually hinder tissue regeneration. "Some biomaterials like hydroxyapatite particles, which are chemically similar to the mineral component of bone, may actually interfere with regeneration," Dr. Wikesjö says. "They may not r...

Secrets of the sea yield stronger artificial bone

...froze it. Just like the impurities in sea ice, the hydroxyapatite concentrates in the space between the ice crystals...on, the result is a porous scaffolding composed of hydroxyapatite that exhibits striking similarities to nacre's mul...he scaffolding four times stronger than the porous hydroxyapatite materials currently used in bone substitutes." ...

'Nanospheres' that block pain of sensitive teeth

...creating tiny spheres of a ceramic material called hydroxyapatite could be a long term solution or cure for sensitiv...rying to synthesize nanospheres of hydroxyapatite. hydroxyapatite is a ceramic material which is highly compatible w...he bone material). Earl and his colleagues grew hydroxyapatite at various pH levels to vary the size of the parti...

Nanotubes inspire new technique for healing broken bones

...ssue is a natural composite of collagen fibers and hydroxyapatite crystals. Haddon and his coworkers have demonstrat...the role of collagen as the scaffold for growth of hydroxyapatite in bone. "This research is particularly notable... nanotubes are not sufficient, since the growth of hydroxyapatite crystals relies on the ability of the scaffold to ...

Hydroxyapatite in Biological Technology

Purification of Recombinant Flavonone 3beta-Hydroxylase Using Bio-Scale CHT5-1 Hydroxyapatite Column

Introduction Flavanone 3b-hydroxylase (FHT), a typical 2-oxoglutaratedependent dioxygenase, catalyzes the 3b-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavanoids, catechins, proanthocyanid...

Purification of Murine IgG1 Using UNOsphere S and CHT Ceramic Hydroxyapatite Chromatography, Rev A

Purification of Murine IgG1 Using UNOsphere S and CHT Ceramic Hydroxyapatite Chromatography, Rev A Henry Lai, PhD, and Samuel G Franklin, PhD, Bio-Rad Laboratories, Inc., 2000 Alfred Nobel Drive, Hercules, CA 94547 USA Introduct...

Pioneer(R) Surgical Technology Announces First Human Implants of New nanOss(TM)-Cervical Fusion Device

...machined from mechanically robust nano-crystalline hydroxyapatite (HA) and is designed to function as bone. The surg...man of the Board, Dr. Matthew N. Songer says, "The hydroxyapatite nanOss-Cervical design is the frontier of the new ...roval for a nanotechnology device -- nanOss(TM) -- hydroxyapatite bone void filler. Pioneer's Orthopaedic, Spine, an...

Pioneer(R) Surgical Technology Announces Market Release of FortrOss(TM), a Next Generation Bone Void Filler

...mimic the nanostructures inherent in bone tissue. According to Dr. Edward Ahn, Vice President of Biomaterials at Pioneer states, "Because the nanOss hydroxyapatite in FortrOss resembles the size, shape, and chemistry of native bone, bone tissue has a great affinity for nanOss and recognizes it as native tissue. T...

Pioneer(R) Surgical Technology Announces First Human Implants of its NuNec(TM) Cervical Arthroplasty Device

...E-Matrix(TM) for tissue regeneration. Angstrom(TM) Medica, Inc. is the first company to obtain FDA approval for a nanotechnology device - NanOss(TM) - hydroxyapatite bone void filler. The company's three division - Orthopedic, Spinal and Biologic - all work to produce state of the art, cost-effective solutions for ...

Biologics, Derma Fillers are Key to Dermatological Drug Market Growth

...riasis and a host of other conditions -- including bio-engineered collagen, hydroxyapatite fillers and new biologic agents," notes Mary Ann Crandall, the author of th...ed in the United States. For longer-lasting results there is the new filler hydroxyapatite with a methylcellulose vehicle and a recently approved permanent injectable...

Preparative Nondenaturing Gel Electrophoresis Used in the Purification of an Esterase Involved in Insecticide Resistance, Rev C

...ogenate by sequential ion exchange, hydrophobic interaction, and hydroxyapatite chromatography, followed by a final purification step using the ...ately 0.5 ml. The sample remained in the elution buffer from the hydroxyapatite column, that is, approximately 60 mM phosphate buffer (pH 6.8). ...