Ranbaxy Secures Final FDA Approval for Quinapril Hydrochloride + Hydrochlorothiazide Tablets

PRINCETON, N.J., March 5 /PRNewswire/ -- Ranbaxy Pharmaceuticals Inc. (RPI), a wholly owned subsidiary of Ranbaxy Laboratories Limited (RLL), announced today that RLL has received approval from the U.S. Food and Drug Administration to manufacture and market Quinapril Hydrochloride & Hydrochlor...

Video: FDA approves Exforge HCT(R) - the Only High Blood Pressure Treatment to Combine Three Medications in a Single Pill

...maximum dose of Exforge HCT (amlodipine/valsartan/ hydrochlorothiazide 10 mg/320 mg/25 mg) demonstrated significantly gre...ecautions (5.1 )] Because of the hydrochlorothiazide component, EXFORGE HCT is contraindicated in patie...required. Important considerations due to the hydrochlorothiazide component of EXFORGE HCT: Thiazides have been rep...

One Pill Might Prevent Heart Disease

...ogy annual meeting in Orlando, Fla., and online in The Lancet . The polypill contains generic versions of the blood pressure medications atenolol, hydrochlorothiazide and rampiril, as well as simvastatin (Zocor) and aspirin. It is designed to attack three major risk factors of cardiovascular disease -- high blood pr...

Mylan Announces Tentative FDA Approval for Generic Version of Antihypertensive Avalide(R) Tablets

...A) for its Abbreviated New Drug Application (ANDA) for Irbesartan and Hydrochlorothiazide Tablets, 150 mg/12.5 mg and 300 mg/12.5 mg. Irbesartan and hydrochlorothiazide Tablets, indicated for the treatment of hypertension, are the generic version of Sanofi Aventis' Avalide(R) Tablets, which had U.S. sales of approxima...

2-drug blood pressure therapy lowers cardiovascular risk

...nts in the study received no more than 40 milligrams of benazepril in each dose; amlodipine doses began at 5 mg and could be increased to 10 mg, while hydrochlorothiazide doses began at 12.5 mg and could be increased to 25 mg. Many studies have already shown that reducing blood pressure can reduce the risk of stroke,...

Sanofi-aventis Announces a Good Third Quarter Performance; Increase in 2007 full-year earnings growth guidance

...ittee of the FDA recommended approval of Avalide(R) as an initial treatment for hypertension. Avalide(R) is a fixed-dose combination of irbesartan and hydrochlorothiazide that is currently approved for the treatment of hypertension in patients with blood pressure uncontrolled on monotherapy. If approved, the new indicat...

Beta-Blockers Should Not Be First Choice for High Blood Pressure

...than patients who use calcium channel blockers such as Norvasc and Cardizem to manage their blood pressure. Patients who take diuretics such as hydrochlorothiazide or a group of drugs called RAS inhibitors (brand names include Altace, Lotensin, and Cozaar) have risks similar to those taking beta-blockers. D...

Hydrochlorothiazide in Medical Technology

King Pharmaceuticals Announces Plan to Present Results from Phase III Clinical Trial Evaluating ALTACE as Monotherapy and in Combination with Hydrochlorothiazide at the American Society of Hypertension Annual Meeting

BRISTOL, Tenn.--(BUSINESS WIRE)--May 8, 2007 - King Pharmaceuticals, Inc. (NYSE:KG) announced today that the results from a Phase III clinical trial for its ALTACE(R) (ramipril) diuretic combination product will be presented at the American Society of Hypertension's Twenty-Second Annual Scientific ...

King Pharmaceuticals Reports Efficacy of Altace 20mg And Efficacy of a Combination of Altace 20mg And Hydrochlorothiazide 25mg For 24-hour Blood Pressure Control

BRISTOL, Tenn.--(BUSINESS WIRE)--May 19, 2007 - King Pharmaceuticals, Inc. (NYSE:KG) reported today that data from its Phase III clinical trial evaluating Altace (ramipril) 20mg and the combination of ALTACE 20mg and hydrochlorothiazide (HCT) 25mg were presented this weekend at the American Society...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... approved direct renin inhibitor, and the diuretic hydrochlorothiazide (HCTZ), one of the most commonly-used high blood p...us combinations of Tekturna (75 mg to 300 mg) plus hydrochlorothiazide (6.25 mg to 25 mg) once daily (without titrating u...pressure response. The combination of Tekturna and hydrochlorothiazide resulted in additive placebo-adjusted decreases in...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

...ormation for BENICAR HCT also includes the following warnings regarding its hydrochlorothiazide component: BENICAR HCT is not recommended in patients with severe renal ...atic coma. Hypersensitivity Reaction Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial ast...

New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering

...ormation for BENICAR HCT also includes the following warnings regarding its hydrochlorothiazide component: BENICAR HCT is not recommended in patients with severe renal i...e hepatic coma. Hypersensitivity Reaction Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial ast...

New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)

...ormation for BENICAR HCT also includes the following warnings regarding its hydrochlorothiazide component: BENICAR HCT is not recommended in patients with severe renal i...e hepatic coma. Hypersensitivity Reaction Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial ast...

Lotrel, a Single-Pill Combination for Treating High Blood Pressure, Reduced Cardiovascular Events by 20% in High-Risk Patients

...essure patients treated with Lotrel(R) (amlodipine besylate and benazepril HCl) had 20% fewer cardiovascular events than those taking a benazepril and hydrochlorothiazide (HCTZ) combination. This is the first cardiovascular outcomes trial in a hypertensive population where all patients were randomized to receive a singl...

Powerful New Efficacy Data in Moderate and Severe Hypertensive Patients Supports FDA Approval of AVALIDE(R) (Irbesartan-Hydrochlorothiazide) as the First Combination Therapy for Initial Use in Patients Likely to Need Multiple Drugs to Achieve Their Blood

...(n=328), irbesartan 150 mg monotherapy (n=106), or hydrochlorothiazide 12.5 mg monotherapy (n=104). After two weeks, all ...cified adverse events on AVALIDE vs. irbesartan or hydrochlorothiazide monotherapy were: hypotension (0.9% vs. 0% and 0%)...onatal Morbidity and Mortality. -- Because of the hydrochlorothiazide component, AVALIDE is contraindicated in patie...

New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard Therapy in Treatment of Hypertension

...with hypertension who do not respond to first-line hydrochlorothiazide treatment J Jordan, SW Boye, S Le Breton, DL Keefe...; Poster 401 * The combination of aliskiren with hydrochlorothiazide provided significant additional blood pressure red...eeks of treatment. Aliskiren in combination with hydrochlorothiazide is effective and well tolerated during long-term t...

Benicar HCT Reductions in Seated Systolic Blood Pressure for Stage 2 Patients Compared With Amlodipine + Benazepril

...ormation for BENICAR HCT also includes the following warnings regarding its hydrochlorothiazide component: BENICAR HCT is not recommended in patients with severe renal i...e hepatic coma. Hypersensitivity Reaction Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial ast...

Hydrochlorothiazide in Biological Technology

Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure

...CT combines first approved direct renin inhibitor with the diuretic hydrochlorothiazide (HCTZ) in a single tablet - Data show combination of Tekturna and HCTZ res...R) (aliskiren), the first approved direct renin inhibitor, and the diuretic hydrochlorothiazide (HCTZ). To view the Multimedia News Release, go to: http://www.prnewsw...