Early Prediction of Huntingtons Disease is Possible by Subtle Signs
US researchers have shown that subtle signs may enable early prediction of Huntingtons
disease, an incurable genetic disorder that affects movement , thinking, and some aspects of personality.
Dr. Jane S. Paulsen of the University of Iowa Roy J. and Lucille A. Carver College of Medicine in...
Research identifies trigger that sets of Huntingtons disease
Researchers have discovered the key molecule that gets over activated by the protein of the Huntingtons
disease// and sets way for the condition to be expressed.
Huntingtons disease is a genetic disorder that slowly destroys the ability of the person to think or move by himself. Early symptoms o...
Researchers develop first transgenic monkey model of Huntington's disease
...tments for a range of neurological diseases.
is an inherited disease caused by a defective gene...changes in the brain and behavior that humans with huntingtons
disease experience, said John D. Harding, Ph.D., d...irector of the NINDS. Now, with a primate model of huntingtons
disease, we are one large step closer to finding b...
Business of drug development on verge of great change
...mission is to develop new therapeutics for diseases with no disease modifying treatments such as Parkinsons and Alzheimers, or orphan diseases such as huntingtons
and Amyotrophic Lateral Sclerosis (Lou Gehrigs), she states. There are smaller numbers of patients affected by orphan diseases -- treatments for them ...
Spit tests may soon replace many blood tests
...pse of the function of the core proteins. In addition, a number of the salivary proteins were found to match proteins with known roles in Alzheimers, huntingtons
and Parkinsons diseases; breast, colorectal and pancreatic cancer; and type I and II diabetes. Specifically, a majority of the proteins were found to ...
Increased level of magnetic iron oxides found in Alzheimer's disease
... dysregulation of iron transport and storage has been found to be associated with many other neurodegenerative conditions,
such as Parkinsons disease, huntingtons
disease (HD), multiple sclerosis and Amyotrophic Lateral Sclerosis. In recent years, a hereditary neurodegenerative disease, neuroferritinopathy, has ...
New stem cell technique improves genetic alteration
...ientists to study and potentially treat thousands of disorders ranging from huntingtons
disease to muscular dystrophy and diabetes.
The technique for the first ...are monogenic, according to the World Health Organization. Examples include huntingtons
disease, sickle cell anemia, cystic fibrosis and hemophilia.
UCI is at t...
Iron banded worms drying out of blood could be linked to Parkinson's and Alzheimer's
...to cause some forms of Parkinsons & Alzheimers and huntingtons
Human blood relies on a protein calle... in neurodegenerative diseases such as Parkinsons, huntingtons
Transferrin takes up iron out of... cause of some forms of Parkinsons, Alzheimers and huntingtons
diseases. Until now there has been no real idea as...
Mental and physical exercise delays dementia in fatal genetic disease
...harajah and Dr Anthony Hannan showed mice with the huntingtons
disease gene displayed impairments on learning and...lems. This closely correlates with observations in huntingtons
However, Dr Jess Nithiananth...hianantharajah said.
We also showed that in the huntingtons
disease mice, specific molecular changes occur tha...
International consortium announces the 1000 Genomes Project
...d to disease. The first type is very rare genetic variants that have a severe effect, such as the variants responsible for causing cystic fibrosis and huntingtons
disease. To find these rare variants, which typically affect fewer than one in 1,000 people, researchers often must spend years on studies involving a...
22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey
... in animal studies has elucidated mechanisms involved in mental disorders. Breakthroughs in molecular genetics shed light on hereditary diseases, i.e. huntingtons
disease and other life-threatening disorders.
The interaction between nerve cells that underlies complex mental functions such as thinking, learni...
Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain
...ovel therapies to treat Alzheimer's disease, amyotrophic lateral sclerosis, huntingtons
disease, epilepsy, stroke/ischemia, dementia and malignant gliomas
RICH...ions, which eventually could lead to therapies to treat Alzheimers disease, huntingtons
disease, epilepsy, stroke, dementia and malignant gliomas.
Promising new drug targets identified for Huntington's disease
...r Rubinsztein. "In collaboration with Cahir OKanes group in Cambridge and Summit Plc, we have shown that these drugs can alleviate the toxicity of the huntingtons
disease mutation in cell-based, fly and zebrafish models. The big question for us is whether they will do the same in humans."
One of the drugs tes...
Overexcited neurons not good for cell health
...sts wanted to see if they could cause the protein, which is associated with huntingtons
disease, to show its toxicity prematurely. (If misfolded or damaged protein...ounding cells, influencing protein homeostasis, said Morimoto, an expert on huntingtons
disease, amyotrophic lateral sclerosis (ALS) and the cellular and molecular...
Genetic contributions to human brain morphology and intelligence
... approach to find genes involved in brain structure that has been applied in several studies is that of diseases with a clear genetic etiology such as huntingtons
disease, Down syndrome, Williams syndrome, and Velocardiofacial syndrome. A review reveals for these diseases besides disease specific brain changes, ...
Tufts University biologists link Huntington's disease to health benefits in young
...rchers in neurology have believed that people with huntingtons
disease have more children than the general popula...llenged that notion by suggesting that people with huntingtons
have more children because they are healthier - no...dical Hypothesis and will soon appear in print.
is a disease that may have beneficial health effec...
Antioxidant overload may underlie a heritable human disease
...l. Our findings open up a whole new line of investigation in protein aggregation diseases, including neurodegenerative diseases such as Alzheimers and huntingtons
disease, Benjamin said. ...
Angel groups in Chicagoland beginning to sprout
... New York City and spent a good portion of his life there.
He finally died at age 55 on Oct. 3, 1967 at Creedmore State Hospital in Queens, N.Y. of huntingtons
Chorea (a debilitative disease he had been diagnosed with 13 years earlier). Early in his career, Bob Dylan traveled to New York City from his native ...
Antibodies for Studying NMDA Receptor Protein Expression and
...y. 1 This receptor has also been linked to
conditions involving injury neurotoxicity and in pathological states, such as
epilepsy and Parkinsons, huntingtons
and Alzheimers diseases. 2
Molecular cloning studies indicate that five NMDA receptor genes exist,
including NMDAR1 (NR1) and four NR2 subunits...