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Homeobox in Medical News

Catastrophic Epilepsy Caused by Defect in One Gene

...ith a new class of drugs not previously explored for this disorder." Noebels and his team found that a mutation on a gene called Aristaless-related homeobox (ARX) caused catastrophic epilepsy-like symptoms in mice, including muscle spasms, seizures, learning disabilities and reduced social interaction. ...

Findings in Epilepsy Gene in Animals May Guide Treatment Directions for Infants

...of these later problems could be prevented," added Golden. Neurologists previously knew that mutations in Arx , the X-linked aristaless-related homeobox gene, were associated with abnormal brain development, neurocognitive problems, and with childhood neurological conditions involving seizures and spas...

Findings in epilepsy gene in animals may guide treatment directions for infants

...ome of these later problems could be prevented," added Golden. Neurologists previously knew that mutations in Arx, the X-linked aristaless-related homeobox gene, were associated with abnormal brain development, neurocognitive problems, and with childhood neurological conditions involving seizures and spas...

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

...ol. According to Testa, Dlx5 is basically a good gene that starts to do bad things when it moves into a dangerous neighborhood. Dxl5 is part of the homeobox family of genes, which direct the timing of events in the physical development of a growing fetus, such as when to sprout a limb, for example. In adul...
Homeobox in Biological News

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... active in healthy adult cells, so it represents a much more 'druggable' target for cancer inhibition." According to Testa, DLX5 is a member of the homeobox family of genes, which direct the timing of events in the physical development of a growing fetus, such as when to sprout a limb, for example. In adul...

A big bunch of tomatoes?

...se mutant tomato plants. They identified the genes responsible: the anantha (AN) and compound inflorescence (S) genes. S is a member of the well known homeobox gene family, which plays a crucial regulatory role in patterning both animals and plants. Lippman et al. have shown that manipulation of these genes i...

Genomics of large marine animals showcased in the biological bulletin

...drothermal vent tubeworm Ridgeia piscesae, by Spencer V. Nyholm, Julie Robindart and Peter R. Girguis Does the high gene density in the sponge NK homeobox gene cluster reflect limited regulatory capacity? by Bryony Fahey, Clair Larroux, Ben Woodcroft and Bernard M. Degnan Insights from a sea lamprey ...
Homeobox in Biological Technology

Quantitative Analysis of Protein-DNA Associations in Vivo Using Real-Time PCR, Rev A

... promoter, Mol Cell Biol 20, 900911 (2000) Waeber G et al., Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor, Mol Endocrinol 10, 13271334 (1996) Watada H et al., The human glucokinase gene β-cell-type promoter: an essential ro...
Homeobox in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... CDX2, a member of the caudal-related homeobox family, is an intestine-specific transcription factor that regulates both proliferation and differentiation in intestinal epithelial cells. It plays a...
Company:BioGenex
Homeobox in Biological Definition

Homeobox

A homeobox is a stretch of DNA sequence found in genes involved in the regulation of the development ( morphogenesis ) of animals , fungi and plants . Genes that have a homeobox are called homeobox genes and form the homeobox gene family . A homeobox is about 180 base pairs long; ...

Gene

...nce been shown to have exceptions, such as reverse transcription in retroviruses . See also Genetics , Gene expression , Gene therapy , homeobox , Human Genome Project , Genomics , DNA , Protein , Gene family Genetic programming , Genetic algorithm Meme , Memetics List of not...

List of gene families

...rotein families 3.1 Motor proteins 3.2 Signal transducing proteins 3.3 Transporters Genes-encoding regulatory proteins homeobox ( Hox gene family) Achaete-scute complex ( Neuroblast formation) Genes-encoding immune system proteins Major histocompatibility ...
Homeobox in Biological Dictionary

Homeobox

A homeobox is a DNA sequence found within genes that are involved in the regulation of patterns of development (morphogenesis) in animals, fungi and plants. 1 The homeobox . 2 Sequence conservation. 3 The homeodomain. 4 Genes Regulated by Hox Genes ... The homeobox sequence codes ...

Spermatogenesis

...a complex process by ... Spermatogenesis ... This page covers the topic of spermatogenesis , the production of the male gametes. ... Hedgehog homeobox signaling in Spermatogenesis Deletion of Dhh, a hedgehog ... Spermatogenesis summary with 9 pages of encyclopedia entries, essays, summaries, ...

Homeotic mutation

...eviations ... There are several homeotic mutations in flower s ... homeobox summary with 12 pages of encyclopedia entries, essays, summaries, research ...Homeotic mutation from Biology-Online.org dictionary. ... mutation in homeobox genes resulting in homeotic ... ... function of a homeotic gene i...

Gene regulatory network

...work studied by Sternberg and his colleagues controls the ... Gene Regulatory Networks for the 36 TF families in human, mouse, and rat. ... homeobox gene . HOXA, HOXB, HOXD series, CHX10, MSX1, MSX2, TLX1, PBX2. LEF ... A quartet of studies by researchers at the California Institute of Technol...

Dorsal lip

...ld it has been shown that the dorsal lip tissue is a ... Xnot2, a homeobox gene that is expressed in the dorsal lip ... descendant of the dorsal blastopore lip . MATERIALS AND METHODS ... homeobox gene expressed in the dorsal lip , then in head mesoderm. A. B. C. A. ...
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(Date:7/9/2014)... at the Perelman School of Medicine at the University ... Institute have received an $8 million grant from the ... photodynamic light therapy (PDT) in patients with malignant pleural ... often manifests itself in the lining of the lungs ... The grant will fund a clinical trial and additional ...
(Date:7/9/2014)... A network of signals active in almost all types ... into overdrive, and may help fuel a tumour,s uncontrolled ... of Cancer Research, London, identified a molecular trigger responsible ... the cellular factory that makes the building blocks ... in the TOR signalling pathway, called SREBP, controls the ...
(Date:7/9/2014)... researchers have uncovered mutations in a cell-signaling pathway that ... may expand treatments for patients because drugs targeting some ... in clinical trials. , Reporting July 9 in ... including researchers at Washington University School of Medicine in ... tumors from 230 patients with lung adenocarcinoma. , "This ...
(Date:7/9/2014)... Cancer Center paint a relatively optimistic picture of women,s ... have spread to the chest wall or skin, but ... skin, regardless of size and whether they have involved ... and called "locally advanced" tumors, suggesting that they are ... survival. Locally advanced breast cancers of this and other ...
(Date:7/9/2014)... used in policing injection drug users in Russia ... , A study, conducted by researchers from ... in collaboration with St. Petersburg Pavlov State University, ... on the health outcomes of a cohort of ... , Those who were arrested by police were ...
Breaking Medicine News(10 mins):Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Signal may send cancer's cellular factories into overdrive 2Health News:Lung cancer study hints at new treatments 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 3Health News:BU researchers relate arrests with HIV risk environment 2
(Date:7/9/2014)... bladders of healthy women differ from bacteria in ... to researchers from Loyola University Chicago Stritch School ... 9, 2014, in the American Society for Microbiology,s ... communities may play a role in female urinary ... common, yet poorly understood, condition with symptoms similar ...
(Date:7/9/2014)... RIVERSIDE, Calif. Jason Stajich , an associate ... the University of California, Riverside, has been awarded the ... of America, a scientific society dedicated to advancing the ... all kinds including mushrooms, molds, truffles, yeasts, lichens, plant ... peer-nominated and each year recognizes an outstanding early-career mycologist. ...
(Date:7/9/2014)... which animals can be found, concern mounts over the ... range for a host mean new territory for its ... of UC Santa Barbara scientists, including parasitologists Ryan Hechinger ... Journal of Biogeography , Hechinger, Kuris and colleagues ... Hosts may actually lose their parasites when the hosts ...
Breaking Biology News(10 mins):UC Riverside plant pathologist receives national recognition 2Not at home on the range 2Not at home on the range 3Not at home on the range 4
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