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Homeobox in Medical News

Catastrophic Epilepsy Caused by Defect in One Gene

...ith a new class of drugs not previously explored for this disorder." Noebels and his team found that a mutation on a gene called Aristaless-related homeobox (ARX) caused catastrophic epilepsy-like symptoms in mice, including muscle spasms, seizures, learning disabilities and reduced social interaction. ...

Findings in Epilepsy Gene in Animals May Guide Treatment Directions for Infants

...of these later problems could be prevented," added Golden. Neurologists previously knew that mutations in Arx , the X-linked aristaless-related homeobox gene, were associated with abnormal brain development, neurocognitive problems, and with childhood neurological conditions involving seizures and spas...

Findings in epilepsy gene in animals may guide treatment directions for infants

...ome of these later problems could be prevented," added Golden. Neurologists previously knew that mutations in Arx, the X-linked aristaless-related homeobox gene, were associated with abnormal brain development, neurocognitive problems, and with childhood neurological conditions involving seizures and spas...

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

...ol. According to Testa, Dlx5 is basically a good gene that starts to do bad things when it moves into a dangerous neighborhood. Dxl5 is part of the homeobox family of genes, which direct the timing of events in the physical development of a growing fetus, such as when to sprout a limb, for example. In adul...
Homeobox in Biological News

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... active in healthy adult cells, so it represents a much more 'druggable' target for cancer inhibition." According to Testa, DLX5 is a member of the homeobox family of genes, which direct the timing of events in the physical development of a growing fetus, such as when to sprout a limb, for example. In adul...

A big bunch of tomatoes?

...se mutant tomato plants. They identified the genes responsible: the anantha (AN) and compound inflorescence (S) genes. S is a member of the well known homeobox gene family, which plays a crucial regulatory role in patterning both animals and plants. Lippman et al. have shown that manipulation of these genes i...

Genomics of large marine animals showcased in the biological bulletin

...drothermal vent tubeworm Ridgeia piscesae, by Spencer V. Nyholm, Julie Robindart and Peter R. Girguis Does the high gene density in the sponge NK homeobox gene cluster reflect limited regulatory capacity? by Bryony Fahey, Clair Larroux, Ben Woodcroft and Bernard M. Degnan Insights from a sea lamprey ...
Homeobox in Biological Technology

Quantitative Analysis of Protein-DNA Associations in Vivo Using Real-Time PCR, Rev A

... promoter, Mol Cell Biol 20, 900911 (2000) Waeber G et al., Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor, Mol Endocrinol 10, 13271334 (1996) Watada H et al., The human glucokinase gene β-cell-type promoter: an essential ro...
Homeobox in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... CDX2, a member of the caudal-related homeobox family, is an intestine-specific transcription factor that regulates both proliferation and differentiation in intestinal epithelial cells. It plays a...
Company:BioGenex
Homeobox in Biological Definition

Homeobox

A homeobox is a stretch of DNA sequence found in genes involved in the regulation of the development ( morphogenesis ) of animals , fungi and plants . Genes that have a homeobox are called homeobox genes and form the homeobox gene family . A homeobox is about 180 base pairs long; ...

Gene

...nce been shown to have exceptions, such as reverse transcription in retroviruses . See also Genetics , Gene expression , Gene therapy , homeobox , Human Genome Project , Genomics , DNA , Protein , Gene family Genetic programming , Genetic algorithm Meme , Memetics List of not...

List of gene families

...rotein families 3.1 Motor proteins 3.2 Signal transducing proteins 3.3 Transporters Genes-encoding regulatory proteins homeobox ( Hox gene family) Achaete-scute complex ( Neuroblast formation) Genes-encoding immune system proteins Major histocompatibility ...
Homeobox in Biological Dictionary

Homeobox

A homeobox is a DNA sequence found within genes that are involved in the regulation of patterns of development (morphogenesis) in animals, fungi and plants. 1 The homeobox . 2 Sequence conservation. 3 The homeodomain. 4 Genes Regulated by Hox Genes ... The homeobox sequence codes ...

Spermatogenesis

...a complex process by ... Spermatogenesis ... This page covers the topic of spermatogenesis , the production of the male gametes. ... Hedgehog homeobox signaling in Spermatogenesis Deletion of Dhh, a hedgehog ... Spermatogenesis summary with 9 pages of encyclopedia entries, essays, summaries, ...

Homeotic mutation

...eviations ... There are several homeotic mutations in flower s ... homeobox summary with 12 pages of encyclopedia entries, essays, summaries, research ...Homeotic mutation from Biology-Online.org dictionary. ... mutation in homeobox genes resulting in homeotic ... ... function of a homeotic gene i...

Gene regulatory network

...work studied by Sternberg and his colleagues controls the ... Gene Regulatory Networks for the 36 TF families in human, mouse, and rat. ... homeobox gene . HOXA, HOXB, HOXD series, CHX10, MSX1, MSX2, TLX1, PBX2. LEF ... A quartet of studies by researchers at the California Institute of Technol...

Dorsal lip

...ld it has been shown that the dorsal lip tissue is a ... Xnot2, a homeobox gene that is expressed in the dorsal lip ... descendant of the dorsal blastopore lip . MATERIALS AND METHODS ... homeobox gene expressed in the dorsal lip , then in head mesoderm. A. B. C. A. ...
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